Research graph
References from PRL-1-Enhanced PD-MSCs Promote Liver Regeneration by Improving Endothelial Barrier Function via HGF/c-Met Signaling in Liver Injury. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Hepatic venous pressure gradient can predict the development of hepatocellular carcinoma and hyponatremia in decompensated alcoholic cirrhosis
10.1097/meg.0b013e32832a21c1 · 2009 · External reference
Endothelin and vascular function in liver disease
10.1136/gut.2003.024703 · 2004 · External reference
Pivotal role of liver sinusoidal endothelial cells in NAFLD/NASH progression
10.1038/labinvest.2015.95 · 2015 · External reference
Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD
10.1371/journal.pone.0032785 · 2012 · External reference
Liver-targeted nanoparticles delivering nitric oxide reduce portal hypertension in cirrhotic rats
10.1016/j.biopha.2024.116143 · 2024 · External reference
Nitric oxide synthase 3-dependent vascular remodeling and circulatory dysfunction in cirrhosis
10.1016/s0002-9440(10)64331-3 · 2003 · External reference
Adverse effects of immunosuppression after liver transplantation
10.1016/j.bpg.2021.101762 · 2021 · External reference
Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells
10.4252/wjsc.v11.i10.748 · 2019 · External reference
Mesenchymal stromal cells: promising treatment for liver cirrhosis
10.1186/s13287-022-03001-z · 2022 · External reference
Effect of bone marrow-derived mesenchymal stem cells on hepatic fibrosis in a thioacetamide-induced cirrhotic rat model
10.1186/s12876-014-0198-6 · 2014 · External reference
Human umbilical cord-derived mesenchymal stem cells attenuate hepatic stellate cells activation and liver fibrosis
10.1007/s11033-024-09664-6 · 2024 · External reference
Modulation of phosphatase of regenerating liver-1 within placental mesenchymal stem cells instigates the transition between epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition subsequent to hepatic fibrosis
10.3350/cmh.2024.0741 · 2025 · External reference
Enhanced PRL-1 expression in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model
10.1186/s13287-020-02029-3 · 2020 · External reference
Improved therapeutics of modified mesenchymal stem cells: an update
10.1186/s12967-020-02234-x · 2020 · External reference
Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration
10.1152/ajpgi.00084.2014 · 2015 · External reference
Hepatic PTP4A1 ameliorates high-fat diet-induced hepatosteatosis and hyperglycemia by the activation of the CREBH/FGF21 axis
10.7150/thno.79434 · 2023 · External reference
PRL-2 phosphatase is required for vascular morphogenesis and angiogenic signaling
10.1038/s42003-020-01343-z · 2020 · External reference
VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C
10.1371/journal.pone.0027165 · 2011 · External reference
Therapeutic effect of hepatocyte growth factor-overexpressing bone marrow-derived mesenchymal stem cells on CCl(4)-induced hepatocirrhosis
10.1038/s41419-018-1239-9 · 2018 · External reference
Effects of mesenchymal stem cells and VEGF on liver regeneration following major resection
10.1007/s00423-016-1380-9 · 2016 · External reference
Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions
1992 · External reference
Hepatocyte growth factor twenty years on: Much more than a growth factor
10.1111/j.1440-1746.2010.06549.x · 2011 · External reference
A novel vascular modulator, hepatocyte growth factor (HGF), as a potential index of the severity of hypertension
10.1006/bbrc.1997.7800 · 1998 · External reference
HGF/c-Met: A Key Promoter in Liver Regeneration
10.3389/fphar.2022.808855 · 2022 · External reference
Met provides essential signals for liver regeneration
10.1073/pnas.0403412101 · 2004 · External reference
Hepatocyte growth factor promotes liver regeneration and protein synthesis after hepatectomy in cirrhotic rats
2001 · External reference
Hepatocyte growth factor gene therapy of liver cirrhosis in rats
10.1038/5593 · 1999 · External reference
10.1046/j.1440-1746.2000.02146.x
10.1046/j.1440-1746.2000.02146.x · 2000 · External reference
Infusion of Human Mesenchymal Stem Cells Improves Regenerative Niche in Thioacetamide-Injured Mouse Liver
10.1007/s13770-020-00274-4 · 2020 · External reference
Anti-fibrotic effect of chorionic plate-derived mesenchymal stem cells isolated from human placenta in a rat model of CCl(4)-injured liver: potential application to the treatment of hepatic diseases
10.1002/jcb.22873 · 2010 · External reference
Efficacy of Gene Modification in Placenta-Derived Mesenchymal Stem Cells Based on Nonviral Electroporation
10.15283/ijsc20117 · 2021 · External reference
ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity
10.1158/1535-7163.mct-09-1173 · 2010 · External reference
Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers
10.1634/theoncologist.2010-0380 · 2011 · External reference
Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference
10.1002/hep.21570 · 2007 · External reference
Mesenchymal stem cell-conditioned medium reduces liver injury and enhances regeneration in reduced-size rat liver transplantation
10.1016/j.jss.2013.02.009 · 2013 · External reference
Angiogenesis and liver fibrosis
10.4254/wjh.v7.i3.377 · 2015 · External reference
Comprehensive Review of the Vascular Niche in Regulating Organ Regeneration and Fibrosis
10.1093/stcltm/szac070 · 2022 · External reference
The Importance of Increased Vascular Permeability for Stroma Formation in Tumors, Healing Wounds, and Chronic Inflammation
10.3389/fcell.2021.660609 · 2021 · External reference
Vascular endothelial growth factor signaling in health and disease: from molecular mechanisms to therapeutic perspectives
10.1038/s41392-025-02249-0 · 2025 · External reference
HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway
10.1096/fj.06-7660com · 2007 · External reference
VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
10.1038/ncb1486 · 2006 · External reference
Autocrine VEGF signaling is required for vascular homeostasis
10.1016/j.cell.2007.06.054 · 2007 · External reference
Endogenous vascular endothelial growth factor-A (VEGF-A) maintains endothelial cell homeostasis by regulating VEGF receptor-2 transcription
10.1074/jbc.m111.293985 · 2012 · External reference
Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition
10.1158/0008-5472.can-12-3256 · 2013 · External reference
Pentamidine is an inhibitor of PRL phosphatases with anticancer activity
2002 · External reference
Human mesenchymal stem cell transfusion is safe and improves liver function in acute-on-chronic liver failure patients
10.5966/sctm.2012-0034 · 2012 · External reference
Transplantation with autologous bone marrow-derived mesenchymal stem cells for alcoholic cirrhosis: Phase 2 trial
10.1002/hep.28693 · 2016 · External reference
Efficacy and safety of mesenchymal stem cell therapy in liver cirrhosis: a systematic review and meta-analysis
10.1186/s13287-023-03518-x · 2023 · External reference
