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References from In vitro and in vivo antifungal effects and mechanism of Daphnetin against Candida albicans. Local targets link to admitted publications; unresolved targets remain external evidence.
Europe is falling behind on targets to address AMR [J]
10.1016/s1470-2045(25)00711-9 · 2026 · External reference
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond [J]
10.1021/acs.chemrev.0c00199 · 2020 · External reference
Unresolved reference
2025 · External reference
Y132H substitution in Candida albicans sterol 14α-demethylase confers fluconazole resistance by preventing binding to haem [J]
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Plant phenolics and terpenoids as adjuvants of antibacterial and antifungal drugs [J]
10.1016/j.phymed.2017.10.018 · 2017 · External reference
Azole resistance inCandida albicansfrom animals: Highlights on efflux pump activity and gene overexpression [J]
10.1111/myc.12611 · 2017 · External reference
Natural product based approaches to overcome Candida glabrata and emerging AMR threats [J]
10.3389/frabi.2026.1767032 · 2026 · External reference
Bioactive Plant Compounds as Alternatives Against Antifungal Resistance in the Candida Strains [J]
10.3390/pharmaceutics17060687 · 2025 · External reference
Toxicological studies of daphnetin [J]
10.4103/pm.pm_523_17 · 2018 · External reference
Preparation and Antibacterial Activity Evaluation of Daphnetin-Loaded Poloxamers/Polyvinylpyrrolidone Thermosensitive Hydrogels [J]
10.1021/acsabm.4c01348 · 2024 · External reference
Effects of daphnetin on biofilm formation and motility of pseudomonas aeruginosa [J]
10.3389/fcimb.2022.1033540 · 2022 · External reference
Quantitative proteomics approach to investigate the antibacterial response of Helicobacter pylori to daphnetin, a traditional Chinese medicine monomer [J]
10.1039/d0ra06677j · 2021 · External reference
Silver Nanoparticles Prepared Using Magnolia officinalis Are an Effective Antimicrobial Agent on Candida albicans, Escherichia coli, and Staphylococcus aureus [J]
10.1007/s12602-023-10179-y · 2023 · External reference
Essential Oils From Citrus unshiu Marc. Effectively Kill Aeromonas hydrophila by Destroying Cell Membrane Integrity, Influencing Cell Potential, and Leaking Intracellular Substances [J]
10.3389/fmicb.2022.869953 · 2022 · External reference
Antibacterial and antibiofilm properties of dichloromethane fraction of extracts from adventitious roots of Eurycoma longifolia against Staphylococcus aureus [J]
10.1016/j.lwt.2022.113438 · 2022 · External reference
Amphipathic Peptide Antibiotics with Potent Activity against Multidrug-Resistant Pathogens [J]
10.3390/pharmaceutics13040438 · 2021 · External reference
Amino Acid Conjugated Polymers: Antibacterial Agents Effective against Drug-Resistant Acinetobacter baumannii with No Detectable Resistance [J]
10.1021/acsami.9b09016 · 2019 · External reference
Design and synthesis of new N-terminal fatty acid modified-antimicrobial peptide analogues with potent in vitro biological activity [J]
10.1016/j.ejmech.2019.111636 · 2019 · External reference
Bioactive Compounds of Ganoderma boninense Inhibited Methicillin-Resistant Staphylococcus aureus Growth by Affecting Their Cell Membrane Permeability and Integrity [J]
10.3390/molecules27030838 · 2022 · External reference
Strategic modification of low-activity natural antimicrobial peptides confers antibacterial potential in vitro and in vivo [J]
10.1016/j.ejmech.2023.115131 · 2023 · External reference
Application of 460 nm visible light for the elimination of Candida albicans in vitro and in vivo [J]
10.3892/mmr.2018.9196 · 2018 · External reference
Bactericidal versus bacteriostatic antibacterials: clinical significance, differences and synergistic potential in clinical practice [J]
10.1093/jac/dkae380 · 2025 · External reference
Antibacterial Effect and Possible Mechanism of Salicylic Acid Microcapsules against Escherichia coli and Staphylococcus aureus [J]
10.3390/ijerph191912761 · 2022 · External reference
Elucidating Antibacterial Activity and Mechanism of Daphnetin against Pseudomonas fluorescens and Shewanella putrefaciens [J]
10.1155/2020/6622355 · 2020 · External reference
Antimicrobial behavior and mechanism of clove oil nanoemulsion [J]
10.1007/s13197-021-05208-z · 2021 · External reference
Measuring Cell Death by Propidium Iodide Uptake and Flow Cytometry [J]
10.1101/pdb.prot087163 · 2016 · External reference
Propidium iodide enabled live imaging of Pasteuria sp.-Pratylenchus zeae infection studies under fluorescence microscopy [J]
10.1007/s00709-020-01567-0 · 2020 · External reference
Cec4 Derived Peptide Inhibits Planktonic and Biofilm Associated Methicillin Resistant Staphylococcus epidermidis [J]
10.1128/spectrum.02409-22 · 2022 · External reference
Detection of Total Reactive Oxygen Species in Adherent Cells by 2',7'-Dichlorodihydrofluorescein Diacetate Staining [J]
10.3791/60682 · 2020 · External reference
Synergistic antifungal effects of botanical extracts against Candida albicans [J]
10.1371/journal.pone.0340665 · 2026 · External reference
Strategies of targeting CYP51 for IFIs therapy: Emerging prospects, opportunities and challenges [J]
10.1016/j.ejmech.2023.115658 · 2023 · External reference
Trends towards lower azole susceptibility among 200 Candida tropicalis bloodstream isolates from Brazilian medical centres [J]
10.1016/j.jgar.2021.03.018 · 2021 · External reference
Research progress on the drug resistance mechanisms of Candida tropicalis and future solutions [J]
10.3389/fmicb.2025.1594226 · 2025 · External reference
Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001–2006: Overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database [J]
10.1086/651263 · 2010 · External reference
Global incidence and mortality of severe fungal disease [J]
10.1016/s1473-3099(23)00692-8 · 2024 · External reference
A polyene macrolide targeting phospholipids in the fungal cell membrane [J]
10.1038/s41586-025-08678-9 · 2025 · External reference
Innovative Strategies to Abolish Microbial Persistence in Biofilm Fortresses [J]
10.3390/biom16060887 · 2026 · External reference
Microbial extracellular polymeric substances in the environment, technology and medicine [J]
10.1038/s41579-024-01098-y · 2024 · External reference
Natural product-derived antifungals against Candida albicans: Chemical diversity and mechanisms of action [J]
10.1016/j.bmc.2025.118435 · 2026 · External reference
In Vitro Selection of Enterobacter cloacae with Cefepime, Meropenem, and Ceftazidime-Avibactam Generates Diverse Resistance Mechanisms [J]
10.1093/ofid/ofaa417.025 · 2023 · External reference
Reactive Oxygen Species (ROS)-Mediated Antibacterial Oxidative Therapies: Available Methods to Generate ROS and a Novel Option Proposal [J]
10.3390/ijms25137182 · 2024 · External reference
Oxidative Stress, Antioxidant Capabilities, and Bioavailability: Ellagic Acid or Urolithins? [J]
10.3390/antiox9080707 · 2020 · External reference
Staphylococcus aureus in Inflammation and Pain: Update on Pathologic Mechanisms [J]
10.3390/pathogens14020185 · 2025 · External reference
Design and Synthesis of 2-Methylthio-3-substituted-5,6-dimethylthieno [2,3-d] pyrimidin-4(3H)-ones as Analgesic, Anti-Inflammatory and Antibacterial Agents [J]
10.2174/157340607779317599 · 2006 · External reference
Synthesis, biological evaluation and molecular modeling of novel thienopyrimidinone and triazolothienopyrimidinone derivatives as dual anti-inflammatory antimicrobial agents [J]
10.1016/j.bioorg.2017.12.028 · 2018 · External reference
Biosynthetic Microcin J25 Exerts Strong Antibacterial, Anti-Inflammatory Activities, Low Cytotoxicity Without Increasing Drug-Resistance to Bacteria Target [J]
10.3389/fimmu.2022.811378 · 2022 · External reference
Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2–STAT3 pathway [J]
10.1038/s41598-021-91008-6 · 2021 · External reference
Daphnetin attenuates intestinal inflammation, oxidative stress, and apoptosis in ulcerative colitis via inhibiting REG3A-dependent JAK2/STAT3 signaling pathway [J]
10.1002/tox.23837 · 2023 · External reference
Characterization of Sodium Alginate—Locust Bean Gum Films Reinforced with Daphnetin Emulsions for the Development of Active Packaging [J]
10.3390/polym14040731 · 2022 · External reference
The therapeutic effects of daphnetin in collagen-induced arthritis involve its regulation of Th17 cells [J]
10.1016/j.intimp.2012.04.001 · 2012 · External reference
Regulatory effect of daphnetin, a coumarin extracted from Daphne odora, on the balance of Treg and Th17 in collagen-induced arthritis [J]
10.1016/j.ejphar.2011.08.019 · 2011 · External reference
Daphnetin inhibits the survival of hepatocellular carcinoma cells through regulating Wnt/β-catenin signaling pathway [J]
10.1002/ddr.21920 · 2022 · External reference
Daphnoretin Arrests the Cell Cycle and Induces Apoptosis in Human Breast Cancer Cells [J]
10.1021/acs.jnatprod.2c00504 · 2022 · External reference
Daphnetin attenuates LPS-induced osteolysis and RANKL mediated osteoclastogenesis through suppression of ERK and NFATc1 pathways [J]
10.1002/jcp.28408 · 2019 · External reference