Research graph
References from Pooled Human BM-MSCs and Hyaluronic Acid Restore Disc Matrix Homeostasis and Histological Architecture in a Rat Disc Degeneration Model of Lower Back Pain. Local targets link to admitted publications; unresolved targets remain external evidence.
Chronic Low Back Pain: Prevalence, Impact on Quality of Life, and Predictors of Future Disability
10.7759/cureus.45760 · 2023 · External reference
10.22203/ecm.v028a08
10.22203/ecm.v028a08 · 2014 · External reference
Intervertebral disc degeneration in warmblood horses: histological and biochemical characterization
2022 · External reference
Cell-based strategies for IVD repair: clinical progress and translational obstacles
2021 · External reference
Unresolved reference
2014 · External reference
The issue of heterogeneity of MSC-based advanced therapy medicinal products-a review
10.3389/fcell.2024.1400347 · 2024 · External reference
Small leucine-rich proteoglycans (SLRPs): characteristics and function in the intervertebral disc
2017 · External reference
Global, regional and national burden of low back pain 1990–2019: A systematic analysis of the Global Burden of Disease study 2019
10.1016/j.jot.2021.07.005 · 2022 · External reference
Intervertebral disc degeneration and inflammatory microenvironment: expression, pathology, and therapeutic strategies
2023 · External reference
Unresolved reference
2021 · External reference
Differential collagen expression by outer and inner annulus fibrosus and nucleus pulposus cells seeded in 3-d polymer scaffolds
2003 · External reference
Unresolved reference
2021 · External reference
Unresolved reference
2022 · External reference
Unresolved reference
2023 · External reference
Bone Marrow Multipotent Mesenchymal Stromal Cells as Autologous Therapy for Osteonecrosis: Effects of Age and Underlying Causes
10.3390/bioengineering8050069 · 2021 · External reference
Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix
2023 · External reference
Optimization of a rat lumbar IVD degeneration model for low back pain
10.1002/jsp2.1092 · 2020 · External reference
Unresolved reference
2018 · External reference
Mechanical and thermal sensory testing in normal chondrodystrophoid dogs and dogs with spinal cord injury caused by thoracolumbar intervertebral disc herniations
2016 · External reference
Targeted deletion of the SPARC gene accelerates disc degeneration in the aging mouse
2005 · External reference
Intervertebral disc human nucleus pulposus cells associated with back pain trigger neurite outgrowth in vitro and pain behaviors in rats
2023 · External reference
Advantages of pooling of human bone marrow-derived mesenchymal stromal cells from different donors versus single-donor MSCs
10.1038/s41598-024-62544-8 · 2024 · External reference
Co-regulation of Sox9 and TGF β 1 transcription factors in mesenchymal stem cells regenerated the intervertebral disc degeneration
2023 · External reference
Unresolved reference
2023 · External reference
Effect of the Microenvironment on Mesenchymal Stem Cell Paracrine Signaling: Opportunities to Engineer the Therapeutic Effect
10.1089/scd.2016.0349 · 2017 · External reference
Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section
2021 · External reference
Assessment of functional and behavioral changes sensitive to painful disc degeneration
10.1002/jor.22833 · 2015 · External reference
Complete Freund’s adjuvant-induced intervertebral discitis as an animal model for discogenic low back pain
2009 · External reference
Matrix remodeling during intervertebral disc growth and degeneration detected by multichromatic FAST staining
10.1369/jhc.2008.952184 · 2009 · External reference
Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor
10.1016/j.omtn.2019.02.012 · 2019 · External reference
Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor
10.1016/j.omtn.2019.02.012 · 2019 · External reference
Loss of tenomodulin expression is a risk factor for age‐related intervertebral disc degeneration
2020 · External reference
Effects of Chondroitinase ABC and Chymopapain on Spinal Motion Segment Biomechanics: An: In Vivo: Biomechanical, Radiologic, and Histologic Canine Study
1997 · External reference
Unresolved reference
2019 · External reference
Unresolved reference
2012 · External reference
Comparison of Gait Assessment Scales in Dogs with Spinal Cord Injury from Intervertebral Disc Herniation
10.1089/neu.2019.6804 · 2020 · External reference
Mesenchymal Stromal Cells: Heterogeneity and Therapeutical Applications
10.3390/cells12162039 · 2023 · External reference
Decellularized extracellular matrix-based scaffold and hypoxic priming: A promising combination to improve the phenotype of degenerate intervertebral disc cells
2022 · External reference
Intervertebral disc degeneration-Current therapeutic options and challenges
10.3389/fpubh.2023.1156749 · 2023 · External reference
Unresolved reference
2016 · External reference
Structure, function, aging and turnover of aggrecan in the intervertebral disc
2014 · External reference
Bone marrow-derived mesenchymal stem cells as autologous therapy in dogs with naturally occurring intervertebral disc disease: feasibility, safety, and preliminary results
2017 · External reference
Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier
10.1016/j.intimp.2022.108537 · 2022 · External reference
Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages
10.3389/fimmu.2022.976511 · 2022 · External reference
Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen
10.1016/j.arr.2019.100978 · 2020 · External reference
Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem Cells
10.1016/j.celrep.2020.01.100 · 2020 · External reference
