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References from Mammalian TRIM21 Exhibits Gene-Wide Episodic Diversifying Selection with Statistically Supported and Structurally Positioned Evolutionary Candidate Residues. Local targets link to admitted publications; unresolved targets remain external evidence.
Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function
10.1073/pnas.0609174104 · 2007 · External reference
Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
10.1073/pnas.1014074107 · 2010 · External reference
Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
10.1038/ni.2548 · 2013 · External reference
TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved
10.1073/pnas.0800159105 · 2008 · External reference
Intracellular antibody receptor TRIM21 prevents fatal viral infection
10.1073/pnas.1301918110 · 2013 · External reference
Simultaneous neutralization and innate immune detection of a replicating virus by TRIM21
10.1128/jvi.00647-13 · 2013 · External reference
Positive selection of primate TRIM5α identifies a critical species-specific retroviral restriction domain
10.1073/pnas.0409853102 · 2005 · External reference
Viruses are a dominant driver of protein adaptation in mammals
10.7554/elife.12469 · 2016 · External reference
MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform
10.1093/nar/gkf436 · 2002 · External reference
PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments
10.1093/nar/gkl315 · 2006 · External reference
IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era
10.1093/molbev/msaa015 · 2020 · External reference
ModelFinder: fast model selection for accurate phylogenetic estimates
10.1038/nmeth.4285 · 2017 · External reference
Ultrafast approximation for phylogenetic bootstrap
10.1093/molbev/mst024 · 2013 · External reference
HyPhy: hypothesis testing using phylogenies
10.1093/bioinformatics/bti079 · 2005 · External reference
Gene-wide identification of episodic selection
10.1093/molbev/msv035 · 2015 · External reference
Not so different after all: a comparison of methods for detecting amino acid sites under selection
10.1093/molbev/msi105 · 2005 · External reference
FUBAR: a fast, unconstrained Bayesian approximation for inferring selection
10.1093/molbev/mst030 · 2013 · External reference
Detecting individual sites subject to episodic diversifying selection
10.1371/journal.pgen.1002764 · 2012 · External reference
Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection
10.1093/molbev/msv022 · 2015 · External reference
PAML 4: phylogenetic analysis by maximum likelihood
10.1093/molbev/msm088 · 2007 · External reference
Controlling the false discovery rate: a practical and powerful approach to multiple testing
10.1111/j.2517-6161.1995.tb02031.x · 1995 · External reference
The rapid generation of mutation data matrices from protein sequences
10.1093/bioinformatics/8.3.275 · 1992 · External reference
Evolutionary trees from DNA sequences: a maximum likelihood approach
10.1007/bf01734359 · 1981 · External reference
Toward defining the course of evolution: minimum change for a specific tree topology
10.2307/2412116 · 1971 · External reference