Research graph
References from White matter hyperintensities partly mediate genetically predicted blood pressure effects on vascular dementia. Local targets link to admitted publications; unresolved targets remain external evidence.
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
10.1016/s1474-4422(13)70124-8 · 2013 · External reference
Small vessel disease: mechanisms and clinical implications
10.1016/s1474-4422(19)30079-1 · 2019 · External reference
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis
10.1136/bmj.c3666 · 2010 · External reference
Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: the Three-City (3C)–Dijon Magnetic Resonance Imaging Study
10.1161/circulationaha.110.961052 · 2011 · External reference
Effect of intensive vs standard blood pressure control on probable dementia: a randomized clinical trial
10.1001/jama.2018.21442 · 2019 · External reference
Effect of the blood pressure and antihypertensive drugs on cerebral small vessel disease: a Mendelian randomization study
10.1161/strokeaha.123.045664 · 2024 · External reference
Cerebral small vessel disease genomics and its implications across the lifespan
10.1038/s41467-020-19111-2 · 2020 · External reference
Genetic complexities of cerebral small vessel disease, blood pressure, and dementia
10.1001/jamanetworkopen.2024.12824 · 2024 · External reference
New insights into the genetic etiology of Alzheimer's disease and related dementias
10.1038/s41588-022-01024-z · 2022 · External reference
The causes and consequences of Alzheimer's disease: phenome-wide evidence from Mendelian randomization
10.1038/s41467-022-32183-6 · 2022 · External reference
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
10.1038/s41588-018-0205-x · 2018 · External reference
Unresolved reference
External reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · 2023 · External reference
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases
10.1038/s41588-018-0047-6 · 2018 · External reference
Common protein-altering variant in GFAP is associated with white matter lesions in the older Japanese population
10.1038/s41525-024-00431-x · 2024 · External reference
A global reference for human genetic variation
10.1038/nature15393 · 2015 · External reference
Mendelian randomization analysis with multiple genetic variants using summarized data
10.1002/gepi.21758 · 2013 · External reference
A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization
10.1002/sim.7221 · 2017 · External reference
Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator
10.1002/gepi.21965 · 2016 · External reference
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
10.1093/ije/dyv080 · 2015 · External reference
Orienting the causal relationship between imprecisely measured traits using GWAS summary data
10.1371/journal.pgen.1007081 · 2017 · External reference
Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways
10.1093/ije/dyu176 · 2015 · External reference
Asymptotic confidence intervals for indirect effects in structural equation models
10.2307/270723 · 1982 · External reference
