Research graph
References from Molecular Targeting of UBR2 in Melasma Using Natural Compounds from Scutellaria baicalensis through Integrated Computational Approaches. Local targets link to admitted publications; unresolved targets remain external evidence.
Melasma: Update on Epidemiology, Clinical Presentation, Assessment, and Scoring
10.5812/jssc.120283 · 2022 · External reference
Decoding the Evolution of Melanin in Vertebrates
10.1016/j.tree.2020.12.012 · 2021 · External reference
Skin melanocytes: biology and development
10.5114/pdia.2013.33376 · 2013 · External reference
Signaling Pathways in Melanogenesis
10.3390/ijms17071144 · 2016 · External reference
Keratinocyte–Melanocyte Interactions During Melanosome Transfer
10.1034/j.1600-0749.2001.140402.x · 2001 · External reference
Unresolved reference
2019 · External reference
The dermal stem cell factor and c-kit are overexpressed in melasma: Dermal stem cell factor and c-kit in melasma
10.1111/j.1365-2133.2006.07179.x · 2006 · External reference
Senescent fibroblasts in melasma pathophysiology
10.1111/exd.13814 · 2019 · External reference
Transcriptional Profiling Shows Altered Expression of Wnt Pathway– and Lipid Metabolism–Related Genes as Well as Melanogenesis-Related Genes in Melasma
10.1038/jid.2011.109 · 2011 · External reference
Reduced WIF-1 Expression Stimulates Skin Hyperpigmentation in Patients with Melasma
10.1038/jid.2012.270 · 2013 · External reference
Secreted Frizzled-Related Protein 2 (sFRP2) Functions as a Melanogenic Stimulator; the Role of sFRP2 in UV-Induced Hyperpigmentary Disorders
10.1038/jid.2015.365 · 2016 · External reference
siRNA-mediated knock‐down of COX‐2 in melanocytes suppresses melanogenesis
10.1111/j.1600-0625.2012.01483.x · 2012 · External reference
10.6026/973206300220001
10.6026/973206300220001 · 2026 · External reference
Inhibitory Effect and Mechanism of Scutellarein on Melanogenesis
10.3390/cosmetics8010015 · 2021 · External reference
Pymol: An open-source molecular graphics tool
2002 · External reference
SWISS-MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling
10.1002/elps.1150181505 · 1997 · External reference
IMPPAT 2.0: an enhanced and expanded phytochemical atlas of Indian medicinal plants
10.1021/acsomega.3c00156 · 2023 · External reference
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
10.1002/jcc.21334 · 2009 · External reference
Unresolved reference
2008 · External reference
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
10.1021/acs.jmedchem.5b00104 · 2015 · External reference
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
10.1038/srep42717 · 2017 · External reference
GROMACS: Fast, flexible, and free
10.1002/jcc.20291 · 2005 · External reference
CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all‐atom additive biological force fields
10.1002/jcc.21367 · 2010 · External reference
Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing
10.1021/ci300363c · 2012 · External reference
Molecular dynamics simulation of highly charged proteins: Comparison of the particle-particle particle‐mesh and reaction field methods for the calculation of electrostatic interactions
10.1110/ps.03137003 · 2003 · External reference
Principal Component Analysis for Protein Folding Dynamics
10.1016/j.jmb.2008.10.018 · 2009 · External reference
Construction of the free energy landscape of biomolecules via dihedral angle principal component analysis
10.1063/1.2945165 · 2008 · External reference
SWISS-MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling
10.1002/elps.1150181505 · ExternalCitation · doi-reference
GROMACS: Fast, flexible, and free
10.1002/jcc.20291 · ExternalCitation · doi-reference
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
10.1002/jcc.21334 · ExternalCitation · doi-reference
CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all‐atom additive biological force fields
10.1002/jcc.21367 · ExternalCitation · doi-reference
Principal Component Analysis for Protein Folding Dynamics
10.1016/j.jmb.2008.10.018 · ExternalCitation · doi-reference
Decoding the Evolution of Melanin in Vertebrates
10.1016/j.tree.2020.12.012 · ExternalCitation · doi-reference
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
10.1021/acs.jmedchem.5b00104 · ExternalCitation · doi-reference
IMPPAT 2.0: an enhanced and expanded phytochemical atlas of Indian medicinal plants
10.1021/acsomega.3c00156 · ExternalCitation · doi-reference
Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing
10.1021/ci300363c · ExternalCitation · doi-reference
Keratinocyte–Melanocyte Interactions During Melanosome Transfer
10.1034/j.1600-0749.2001.140402.x · ExternalCitation · doi-reference
Transcriptional Profiling Shows Altered Expression of Wnt Pathway– and Lipid Metabolism–Related Genes as Well as Melanogenesis-Related Genes in Melasma
10.1038/jid.2011.109 · ExternalCitation · doi-reference
Reduced WIF-1 Expression Stimulates Skin Hyperpigmentation in Patients with Melasma
10.1038/jid.2012.270 · ExternalCitation · doi-reference
Secreted Frizzled-Related Protein 2 (sFRP2) Functions as a Melanogenic Stimulator; the Role of sFRP2 in UV-Induced Hyperpigmentary Disorders
10.1038/jid.2015.365 · ExternalCitation · doi-reference
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
10.1038/srep42717 · ExternalCitation · doi-reference
Construction of the free energy landscape of biomolecules via dihedral angle principal component analysis
10.1063/1.2945165 · ExternalCitation · doi-reference
Molecular dynamics simulation of highly charged proteins: Comparison of the particle-particle particle‐mesh and reaction field methods for the calculation of electrostatic interactions
10.1110/ps.03137003 · ExternalCitation · doi-reference
Senescent fibroblasts in melasma pathophysiology
10.1111/exd.13814 · ExternalCitation · doi-reference
The dermal stem cell factor and c-kit are overexpressed in melasma: Dermal stem cell factor and c-kit in melasma
10.1111/j.1365-2133.2006.07179.x · ExternalCitation · doi-reference
siRNA-mediated knock‐down of COX‐2 in melanocytes suppresses melanogenesis
10.1111/j.1600-0625.2012.01483.x · ExternalCitation · doi-reference
Inhibitory Effect and Mechanism of Scutellarein on Melanogenesis
10.3390/cosmetics8010015 · ExternalCitation · doi-reference
Signaling Pathways in Melanogenesis
10.3390/ijms17071144 · ExternalCitation · doi-reference
Skin melanocytes: biology and development
10.5114/pdia.2013.33376 · ExternalCitation · doi-reference
Melasma: Update on Epidemiology, Clinical Presentation, Assessment, and Scoring
10.5812/jssc.120283 · ExternalCitation · doi-reference
10.6026/973206300220001
10.6026/973206300220001 · ExternalCitation · doi-reference
