Research graph
References from Epigenetic Profiling for Early Detection and Treatment Response Monitoring in Non–Small Cell Lung Cancer: Protocol for a Prospective Translational Biomarker Study. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
The National Lung Screening Trial: overview and study design
10.1148/radiol.10091808 · External reference
Reduced lung-cancer mortality with volume CT screening in a randomized trial
10.1056/nejmoa1911793 · External reference
Impact of low-dose CT screening for lung cancer on ethnic health inequities in New Zealand: a cost-effectiveness analysis
10.1136/bmjopen-2020-037145 · External reference
Potential biomarkers for lung cancer screening
10.3978/j.issn.2218-6751.2014.06.04 · External reference
Volumetric computed tomography screening for lung cancer: three rounds of the NELSON trial
10.1183/09031936.00197712 · External reference
Reduced lung-cancer mortality with low-dose computed tomographic screening
10.1056/nejmoa1102873 · External reference
Barriers to low-dose CT lung cancer screening among middle-aged Chinese
10.3390/ijerph17197107 · External reference
Multilevel barriers to the successful implementation of lung cancer screening: why does it have to be so hard?
10.1513/annalsats.201703-204ps · External reference
Cost-effectiveness of a low-dose computed tomography screening programme for lung cancer in New Zealand
10.1016/j.lungcan.2018.08.004 · External reference
Circulating tumor DNA testing-liquid biopsy of a cancer
10.1001/jamaoncol.2020.0346 · External reference
Liquid biopsies come of age: towards implementation of circulating tumour DNA
10.1038/nrc.2017.7 · External reference
Potential applications of circulating tumor DNA technology as a cancer diagnostic tool
10.7759/cureus.4907 · External reference
Utility of circulating tumor DNA in cancer diagnostics with emphasis on early detection
10.1186/s12916-018-1157-9 · External reference
Clinical implications of circulating cell-free DNA quantification and metabolic tumor burden in advanced non-small cell lung cancer
10.1016/j.lungcan.2019.06.014 · External reference
Circulating free tumor DNA in non-small cell lung cancer (NSCLC): clinical application and future perspectives
10.21037/jtd.2018.12.18 · External reference
Prognostic relevance of circulating tumor cells and circulating cell-free DNA association in metastatic non-small cell lung cancer treated with nivolumab
10.3390/jcm8071011 · External reference
Current and future applications of liquid biopsy in nonsmall cell lung cancer from early to advanced stages
10.1183/16000617.0052-2019 · External reference
Liquid biopsy-based biomarkers of treatment response and resistance
10.1016/j.ccell.2020.03.012 · External reference
Detection and localization of surgically resectable cancers with a multi-analyte blood test
10.1126/science.aar3247 · External reference
Detection of circulating tumor DNA in early- and late-stage human malignancies
10.1126/scitranslmed.3007094 · External reference
Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA
10.1038/ng.3805 · External reference
Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma
10.1126/sciadv.abb5427 · External reference
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
10.1038/s41591-020-0933-1 · External reference
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
10.1038/s41586-018-0703-0 · External reference
Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma
10.1038/nmat4997 · External reference
Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
10.1038/s41467-018-07466-6 · External reference
Epigenetic drivers of tumourigenesis and cancer metastasis
10.1016/j.semcancer.2017.08.004 · External reference
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
10.1038/s41467-020-17316-z · External reference
Marked global DNA hypomethylation is associated with constitutive PD-L1 expression in melanoma
10.1016/j.isci.2018.05.021 · External reference
The genetic/non-genetic duality of drug “resistance” in cancer
10.1016/j.trecan.2018.01.001 · External reference
Persistent cancer cells: the deadly survivors
10.1016/j.cell.2020.10.027 · External reference
10.1101/2019.12.08.868828
10.1101/2019.12.08.868828 · External reference
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
10.1016/j.cell.2010.02.027 · External reference
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
10.1038/nature22794 · External reference
Cycling cancer persister cells arise from lineages with distinct programs
10.1038/s41586-021-03796-6 · External reference
The great escape: tumour cell plasticity in resistance to targeted therapy
10.1038/s41573-019-0044-1 · External reference
DMAP2: a pipeline for analysis of whole-genome-scale DNA methylation sequencing data
10.1002/cpz1.70003 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · External reference
Protocol for generating high-quality genome-scale DNA methylation sequencing data from human cancer biospecimens
10.1016/j.xpro.2023.102714 · External reference
Comparative assessment of DNA methylation patterns between reduced representation bisulfite sequencing and Sequenom EpiTyper methylation analysis
10.2217/epi-2016-0176 · External reference
Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis
10.18632/oncotarget.14042 · External reference
scan_tcga tools for integrated epigenomic and transcriptomic analysis of tumor subgroups
10.2217/epi-2016-0063 · External reference
Genome-wide DNA methylation map of human neutrophils reveals widespread inter-individual epigenetic variation
10.1038/srep17328 · External reference
DMAP: differential methylation analysis package for RRBS and WGBS data
10.1093/bioinformatics/btu126 · External reference
Comparison of alignment software for genome-wide bisulphite sequence data
10.1093/nar/gks150 · External reference
Generating multiple base-resolution DNA methylomes using reduced representation bisulfite sequencing
10.1007/978-1-4939-6685-1_16 · External reference
A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA
10.1186/s12920-017-0290-1 · External reference
Placental hypomethylation is more pronounced in genomic loci devoid of retroelements
10.1534/g3.116.030379 · External reference
Sex differences in DNA methylation and expression in zebrafish brain: a test of an extended “male sex drive” hypothesis
10.1016/j.gene.2016.05.042 · External reference
Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing
10.4161/epi.25797 · External reference
Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy
10.1038/s41568-019-0179-8 · External reference
Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer
10.1186/s43556-022-00107-x · External reference
A guide for designing and analyzing RNA-Seq data
10.1007/978-1-4939-7834-2_3 · External reference
Strategy for RNA-Seq experimental design and data analysis
10.1007/978-1-0716-2780-8_16 · External reference
An epigenetic signature of advanced colorectal cancer metastasis
10.1016/j.isci.2023.106986 · External reference
Multi-platform microRNA profiling of hepatoblastoma patients using formalin fixed paraffin embedded archival samples
10.1186/s13742-015-0099-9 · External reference
A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients
10.1038/srep10438 · External reference
RNA-Seq: a revolutionary tool for transcriptomics
10.1038/nrg2484 · External reference
Generating sequencing-based DNA methylation maps from low DNA input samples
10.1007/978-1-0716-2140-0_1 · External reference
Comparison of biomarker modalities for predicting response to PD-1/PD-L1 checkpoint blockade: a systematic review and meta-analysis
10.1001/jamaoncol.2019.1549 · External reference
Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support
10.1016/j.jbi.2008.08.010 · External reference
Comparison of enzymatic and bisulfite-based methods for sequencing-based cell-free DNA methylation profiling
10.3389/freae.2025.1693925 · External reference
Epidemiology and prognosis in young lung cancer patients aged under 45 years old in northern China
10.1038/s41598-021-86203-4 · External reference
Cancer statistics for adolescents and young adults, 2020
10.3322/caac.21637 · External reference
Management of acquired resistance to EGFR TKI-targeted therapy in advanced non-small cell lung cancer
10.1186/s12943-018-0777-1 · External reference
The relationship between tyrosine kinase inhibitor therapy and overall survival in patients with non-small cell lung cancer carrying EGFR mutations
10.5732/cjc.012.10160 · External reference
Osimertinib in NSCLC: real-world data from New Zealand
10.1016/j.jtocrr.2020.100022 · External reference
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
10.1056/nejmoa044238 · External reference
Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) program
10.1016/j.annepidem.2022.10.014 · External reference
Critical factors in the analytical work flow of circulating tumor DNA-based molecular profiling
10.1093/clinchem/hvad194 · External reference