Research graph
References from Metabolomics-Defined Subtypes of Prediabetes and Risk of Cardiovascular-Kidney-Metabolic Outcomes. Local targets link to admitted publications; unresolved targets remain external evidence.
Prediabetes
10.1038/s41572-025-00635-0 · 2025 · External reference
Diagnosis and management of prediabetes: a review
10.1097/ogx.0000000000001177 · 2023 · External reference
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
10.1002/(sici)1096-9136(199807)15:7<539::aid-dia668>3.0.co;2-s · 1998 · External reference
Global prevalence of prediabetes
10.2337/dc22-2376 · 2023 · External reference
Natural history of type 2 diabetes in Indians: time to progression
10.2337/dc23-1514 · 2024 · External reference
Safety and effectiveness of metformin plus lifestyle intervention compared with lifestyle intervention alone in preventing progression to diabetes in a Chinese population with impaired glucose regulation: a multicentre, open-label, randomised controlled trial
10.1016/s2213-8587(23)00132-8 · 2023 · External reference
Age-specific difference in the association between prediabetes and subclinical atherosclerosis: an analysis of a Chinese prospective cohort study
10.1186/s12933-022-01592-8 · 2022 · External reference
Predictive performance of established cardiovascular risk scores in the prediabetic population: external validation using the UK Biobank data set
10.1093/eurjpc/zwad106 · 2023 · External reference
Iohexol clearance, but not estimated GFR, reveals a steeper GFR decline in patients with prediabetes
10.1016/j.kint.2025.06.019 · 2025 · External reference
Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study
10.1016/s0140-6736(06)69701-8 · 2006 · External reference
Long-term effects of a randomised trial of a 6-year lifestyle intervention in impaired glucose tolerance on diabetes-related microvascular complications: the China Da Qing Diabetes Prevention Outcome Study
10.1007/s00125-010-1948-9 · 2011 · External reference
Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications: the DPP Outcomes Study
10.1016/s2213-8587(15)00291-0 · 2015 · External reference
Reduction in the incidence of type 2 diabetes with the Mediterranean diet
10.2337/dc10-1288 · 2011 · External reference
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
10.1056/nejmoa012512 · 2002 · External reference
Fast walking is a preventive factor against new-onset diabetes mellitus in a large cohort from a Japanese general population
10.1038/s41598-020-80572-y · 2021 · External reference
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study
10.2337/diacare.20.4.537 · 1997 · External reference
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
10.1056/nejm200105033441801 · 2001 · External reference
Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes
10.1038/s41591-020-1116-9 · 2021 · External reference
Data-driven subgroups of prediabetes and the associations with outcomes in Chinese adults
10.1016/j.xcrm.2023.100958 · 2023 · External reference
Prediabetes and what it means: the epidemiological evidence
10.1146/annurev-publhealth-090419-102644 · 2021 · External reference
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes
10.1007/s00125-020-05310-5 · 2021 · External reference
Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies
10.2337/dc21-1705 · 2022 · External reference
Integrative metabolomics differentiate coronary artery disease, peripheral artery disease, and venous thromboembolism risks
10.1161/atvbaha.124.321282 · 2024 · External reference
Associations of urine and plasma metabolites with kidney failure and death in a chronic kidney disease cohort
10.1053/j.ajkd.2024.03.028 · 2024 · External reference
Metabolites associated with uremic symptoms in patients with CKD: findings from the Chronic Renal Insufficiency Cohort (CRIC) study
10.1053/j.ajkd.2023.11.013 · 2024 · External reference
Dietary fats and cardiometabolic disease: mechanisms and effects on risk factors and outcomes
10.1038/s41569-019-0206-1 · 2019 · External reference
The UK Biobank resource with deep phenotyping and genomic data
10.1038/s41586-018-0579-z · 2018 · External reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · 2023 · External reference
Diagnosis and classification of diabetes mellitus
10.2337/dc10-s062 · 2010 · External reference
Association between a Mediterranean lifestyle and type 2 diabetes incidence: a prospective UK Biobank study
10.1186/s12933-023-01999-x · 2023 · External reference
Timing of moderate to vigorous physical activity, mortality, cardiovascular disease, and microvascular disease in adults with obesity
10.2337/dc23-2448 · 2024 · External reference
Improving 10-year cardiovascular risk prediction in patients with type 2 diabetes with metabolomics
10.1186/s12933-025-02581-3 · 2025 · External reference
Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications
10.1186/s12933-025-02899-y · 2025 · External reference
Unresolved reference
External reference
Comparison between data-driven clusters and models based on clinical features to predict outcomes in type 2 diabetes: nationwide observational study
10.1007/s00125-021-05485-5 · 2021 · External reference
Cluster-wise assessment of cluster stability
10.1016/j.csda.2006.11.025 · 2007 · External reference
Mendelian randomization
10.1038/s43586-021-00092-5 · 2022 · External reference
Trajectories of type 2 diabetes and cancer in 330 000 individuals with prediabetes: 20-year observational study in England
10.1016/s2213-8587(25)00285-2 · 2026 · External reference
Lipoprotein particle size and concentration by nuclear magnetic resonance and incident type 2 diabetes in women
10.2337/db09-1114 · 2010 · External reference
Dietary intake of linoleic acid, its concentrations, and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of prospective cohort studies
10.2337/dc21-0438 · 2021 · External reference
Metabolomic characterization of frailty identifies subtype-specific management strategies
10.1038/s41746-025-02075-2 · 2025 · External reference
HDL particle subspecies and their association with incident type 2 diabetes: the PREVEND study
10.1210/clinem/dgab075 · 2021 · External reference
High concentration of medium-sized HDL particles and enrichment in HDL paraoxonase 1 associate with protection from vascular complications in people with long-standing type 1 diabetes
10.2337/dc19-0772 · 2020 · External reference
Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts
10.1007/s00125-019-05001-w · 2019 · External reference
Lipoprotein characteristics and incident coronary heart disease: prospective cohort of nearly 90 000 individuals in UK Biobank
10.1161/jaha.123.029552 · 2023 · External reference