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References from Accelerated Brain Aging in Type 1 Diabetes Across Painful and Painless Peripheral Neuropathy: MRI-Based Brain Age Estimates From Deep Learning. Local targets link to admitted publications; unresolved targets remain external evidence.
IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045
10.1016/j.diabres.2021.109119 · 2022 · External reference
Accelerated brain aging in individuals with diabetes: association with poor glycemic control and increased all-cause mortality
10.1016/j.psyneuen.2022.105921 · 2022 · External reference
Diabetes, prediabetes, and brain aging: the role of healthy lifestyle
10.2337/dc24-0860 · 2024 · External reference
Patterns of regional brain atrophy and brain aging in middle- and older-aged adults with type 1 diabetes
10.1001/jamanetworkopen.2023.16182 · 2023 · External reference
Advanced BrainAGE in older adults with type 2 diabetes mellitus
10.3389/fnagi.2013.00090 · 2013 · External reference
Diabetic neuropathy
2019 · External reference
Magnetic resonance neuroimaging study of brain structural differences in diabetic peripheral neuropathy
10.2337/dc13-2610 · 2014 · External reference
Gray matter brain alterations in type 1 diabetes - findings based on detailed phenotyping of neuropathy status
10.1055/a-1835-1877 · 2022 · External reference
Macrostructural brain changes in patients with longstanding type 1 diabetes mellitus - a cortical thickness analysis study
10.1055/s-0033-1345120 · 2013 · External reference
Structural and functional abnormalities of the primary somatosensory cortex in diabetic peripheral neuropathy: a multimodal MRI study
10.2337/db18-0509 · 2019 · External reference
Prevalence and impact on quality of life of peripheral neuropathy with or without neuropathic pain in type 1 and type 2 diabetic patients attending hospital outpatients clinics
10.1016/j.diabet.2008.11.004 · 2009 · External reference
Prevalence and determinants of painful and painless neuropathy in type 1 diabetes mellitus
10.3389/fendo.2019.00402 · 2019 · External reference
Prevalence of painful and painless diabetic peripheral neuropathy in the Northern Danish Region: a population-based study
10.1016/j.pcd.2024.08.006 · 2024 · External reference
Brain-predicted age difference estimated using DeepBrainNet is significantly associated with pain and function-a multi-institutional and multiscanner study
10.1097/j.pain.0000000000002984 · 2023 · External reference
Chronic pain is associated with a brain aging biomarker in community-dwelling older adults
10.1097/j.pain.0000000000001491 · 2019 · External reference
Painful diabetic neuropathy is associated with accelerated epigenetic aging
10.1007/s11357-025-01516-w · 2025 · External reference
Reduced gray matter brain volume and cortical thickness in adults with type 1 diabetes and neuropathy
10.1016/j.neures.2021.10.002 · 2022 · External reference
Cognitive performance in type 1 diabetes patients is associated with cerebral white matter volume
10.1007/s00125-007-0714-0 · 2007 · External reference
Altered surface-based brain morphometry in type 1 diabetes and neuropathic pain
10.1016/j.neuroscience.2024.12.033 · 2025 · External reference
Alterations of peripheral cytokines, BDNF, and surface-based morphometry indices in T2DM patients without cognitive impairment
10.3389/fnins.2023.1141261 · 2023 · External reference
Alterations in functional connectivity of thalamus and primary somatosensory cortex in painful and painless diabetic peripheral neuropathy
10.2337/dc22-0587 · 2023 · External reference
Altered functional connectivity between brain structures in adults with type 1 diabetes and polyneuropathy
10.1016/j.brainres.2022.147882 · 2022 · External reference
Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes
10.1016/j.jdiacomp.2018.12.016 · 2019 · External reference
Neuropathic phenotypes of type 1 diabetes are related to different signatures of magnetic resonance spectroscopy-assessed brain metabolites
10.1016/j.clinph.2024.06.017 · 2024 · External reference
Central nervous system microstructural alterations in type 1 diabetes mellitus: a systematic review of diffusion Tensor imaging studies
10.1016/j.diabres.2023.110645 · 2023 · External reference
Cerebrospinal fluid levels of Alzheimer’s disease biomarkers in middle-aged patients with type 1 diabetes
10.1007/s00125-014-3333-6 · 2014 · External reference
Quantification of white matter hyperintensities in type 1 diabetes and its relation to neuropathy and clinical characteristics
10.1016/j.brainres.2024.149288 · 2025 · External reference
Structural brain alterations in key somatosensory and nociceptive regions in diabetic peripheral neuropathy
10.2337/dc22-1123 · 2023 · External reference
Multimodal MRI analysis selecting key brain features for machine learning based classification of diabetic neuropathic pain and phenotypes
10.1016/j.jns.2025.123701 · 2025 · External reference
Unresolved reference
External reference
Brain structure ages-a new biomarker for multi-disease classification
10.1002/hbm.26558 · 2024 · External reference
Role of sural sensory nerve in the assessment of type 2 diabetes mellitus peripheral polyneuropathy in adults
10.25258/ijddt.12.3.33 · 2022 · External reference
Brain aging mechanisms with mechanical manifestations
10.1016/j.mad.2021.111575 · 2021 · External reference
A new look at painful diabetic neuropathy
10.1016/j.diabres.2018.08.020 · 2018 · External reference
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
10.1007/s11011-025-01700-z · 2025 · External reference
Brain age as a surrogate marker for cognitive performance in multiple sclerosis
10.1111/ene.15473 · 2022 · External reference
Brain age gap, dementia risk factors and cognition in middle age
10.1093/braincomms/fcae392 · 2024 · External reference
A nonlinear simulation framework supports adjusting for age when analyzing BrainAGE
10.3389/fnagi.2018.00317 · 2018 · External reference
Point-of-care nerve conduction device predicts the severity of diabetic polyneuropathy: a quantitative, but easy-to-use, prediction model
10.1111/jdi.13386 · 2021 · External reference
Validity and reliability of a point-of-care nerve conduction device in diabetes patients
10.1111/jdi.13007 · 2019 · External reference