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References from Gene network robustness as a multivariate character. Local targets link to admitted publications; unresolved targets remain external evidence.
Robustness from flexibility in the fungal circadian clock
10.1186/1752-0509-4-88 · 2010 · External reference
Erratum: Sexual reproduction selects for robustness and negative epistasis in artificial gene networks
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Evolutionary capacitance as a general feature of complex gene networks
10.1038/nature01765 · 2003 · External reference
Gene network simulations provide testable predictions for the molecular domestication syndrome
10.1093/genetics/iyab214 · 2022 · External reference
On the distribution of the mean and variance of a quantitative trait under mutation-selection-drift balance.
10.1093/genetics/138.3.901 · 1994 · External reference
Model transcriptional networks with continuously varying expression levels
10.1186/1471-2148-11-363 · 2011 · External reference
Innovation and robustness in complex regulatory gene networks
10.1073/pnas.0705396104 · 2007 · External reference
Perspective: evolution and detection of genetic robustness
10.1111/j.0014-3820.2003.tb00377.x · 2003 · External reference
Mapping phenotypes: canalization, plasticity and developmental stability
10.1016/s0169-5347(01)02266-2 · 2001 · External reference
The evolutionary dynamics of evolvability in a gene network model
10.1111/j.1420-9101.2008.01663.x · 2009 · External reference
xtending extitR with extitC++: A Brief Introduction to extitRcpp
10.7287/peerj.preprints.3188v1 · 2017 · External reference
Canalization, Genetic Assimilation and Preadaptation: A Quantitative Genetic Model
10.1093/genetics/149.4.2119 · 1998 · External reference
Phenotypic plasticity can facilitate adaptive evolution in gene regulatory circuits
10.1186/1471-2148-11-5 · 2011 · External reference
Phenotypic robustness can increase phenotypic variability after nongenetic perturbations in gene regulatory circuits
10.1111/j.1420-9101.2011.02261.x · 2011 · External reference
The origins of mutational robustness
10.1016/j.tig.2015.04.008 · 2015 · External reference
Pervasive robustness in biological systems
10.1038/nrg3949 · 2015 · External reference
Modeling the evolution of complex genetic systems: The gene network family tree
10.1002/jez.b.22597 · 2015 · External reference
The Evolutionary Genetics of Canalization
10.1086/432265 · 2005 · External reference
Modelling 'evo-devo' with RNA
10.1002/bies.10190 · 2002 · External reference
Theoretical Study of the One Self-Regulating Gene in the Modified Wagner Model
10.3390/math6040058 · 2018 · External reference
The developmental-genetics of canalization
10.1016/j.semcdb.2018.05.019 · 2019 · External reference
Measuring and comparing evolvability and constraint in multivariate characters
10.1111/j.1420-9101.2008.01573.x · 2008 · External reference
Modeling Genetic Architecture: A Multilinear Theory of Gene Interaction
10.1006/tpbi.2000.1508 · 2001 · External reference
Epistasis in Polygenic Traits and the Evolution of Genetic Architecture under Stabilizing Selection
10.1086/374204 · 2003 · External reference
Noise Propagation and Signaling Sensitivity in Biological Networks: A Role for Positive Feedback
10.1371/journal.pcbi.0040008 · 2008 · External reference
Evolution of Robustness to Noise and Mutation in Gene Expression Dynamics
10.1371/journal.pone.0000434 · 2007 · External reference
Homeostasis and Differentiation in Random Genetic Control Networks
10.1038/224177a0 · 1969 · External reference
Towards a general theory of adaptive walks on rugged landscapes
10.1016/s0022-5193(87)80029-2 · 1987 · External reference
The evolution of genetic canalization under fluctuating selection
10.1111/j.0014-3820.2000.tb00001.x · 2000 · External reference
Somatic mutations in aging, cancer and neurodegeneration
10.1016/j.mad.2011.10.009 · 2012 · External reference
Phenotypic Plasticity, Developmental Instability, and Robustness: The Concepts and How They Are Connected
10.3389/fevo.2019.00056 · 2019 · External reference
Phenotype–genotype relation in Wagner's canalization model
10.1016/j.jtbi.2012.08.020 · 2012 · External reference
Github Repository for the manuscript "Gene network robustness as a multivariate character". Version 3.1
10.5281/zenodo.6393075 · 2022 · External reference
The Evolution of Canalization and Evolvability in Stable and Fluctuating Environments
10.1007/s11692-012-9218-z · 2013 · External reference
The Genetics and Evolution of Fluctuating Asymmetry
10.1146/annurev.ecolsys.36.102003.152640 · 2005 · External reference
Genes Confer Similar Robustness to Environmental, Stochastic, and Genetic Perturbations in Yeast
10.1371/journal.pone.0009035 · 2010 · External reference
Toward a detailed computational model for the mammalian circadian clock
10.1073/pnas.1132112100 · 2003 · External reference
Canalization and genetic assimilation: Reassessing the radicality of the Waddingtonian concept of inheritance of acquired characters
10.1016/j.semcdb.2018.05.009 · 2019 · External reference
Genetic assimilation can occur in the absence of selection for the assimilating phenotype, suggesting a role for the canalization heuristic
10.1111/j.1420-9101.2004.00739.x · 2004 · External reference
Robustness: mechanisms and consequences
10.1016/j.tig.2009.07.005 · 2009 · External reference
Is evolution predictable? Quantitative genetics under complex genotype‐phenotype maps
10.1111/evo.13907 · 2020 · External reference
Emergence of cooperative bistability and robustness of gene regulatory networks
10.1371/journal.pcbi.1007969 · 2020 · External reference
The nature of robustness in development
10.1002/bies.10093 · 2002 · External reference
Systems biology of robustness and homeostatic mechanisms
10.1002/wsbm.1440 · 2019 · External reference
Modelling the influence of parental effects on gene‐network evolution
10.1111/jeb.13255 · 2018 · External reference
The causes of evolvability and their evolution
10.1038/s41576-018-0069-z · 2019 · External reference
Most Networks in Wagner's Model Are Cycling
10.1371/journal.pone.0034285 · 2012 · External reference
R: A Language and Environment for Statistical Computing
2020 · External reference
When Parameters in Dynamic Models Become Phenotypes: A Case Study on Flesh Pigmentation in the Chinook Salmon (<i>Oncorhynchus tshawytscha</i>)
10.1534/genetics.108.087064 · 2008 · External reference
Compensatory Evolution and the Origins of Innovations
10.1534/genetics.112.148627 · 2013 · External reference
Phenotypic plasticity and population viability: the importance of environmental predictability
10.1098/rspb.2010.0771 · 2010 · External reference
Why and how genetic canalization evolves in gene regulatory networks
10.1186/s12862-016-0801-2 · 2016 · External reference
Unresolved reference
1949 · External reference
Waddington's canalization revisited: Developmental stability and evolution
10.1073/pnas.102303999 · 2002 · External reference
Modeling Transcriptional Control in Gene Networks—Methods, Recent Results, and Future Directions
10.1006/bulm.1999.0155 · 2000 · External reference
Using evolutionary computations to understand the design and evolution of gene and cell regulatory networks
10.1016/j.ymeth.2013.05.013 · 2013 · External reference
Progress on canalization
10.1073/pnas.172388999 · 2002 · External reference
Fitness sensitivity and the canalization of life-history traits
10.1111/j.1558-5646.1994.tb02186.x · 1994 · External reference
Emergence of homeostasis and “noise imprinting” in an evolution model
10.1073/pnas.96.19.10746 · 1999 · External reference
Developmental instability is genetically correlated with phenotypic plasticity, constraining heritability, and fitness
10.1111/evo.12175 · 2013 · External reference
Canalization of development and the inheritance of acquired characters
10.1038/150563a0 · 1942 · External reference
Canalization of Development and Genetic Assimilation of Acquired Characters
10.1038/1831654a0 · 1959 · External reference
Evolution of gene networks by gene duplications: a mathematical model and its implications on genome organization.
10.1073/pnas.91.10.4387 · 1994 · External reference
Does evolutionary plasticity evolve?
10.1111/j.1558-5646.1996.tb02342.x · 1996 · External reference
10.1515/9781400849383
10.1515/9781400849383 · 2013 · External reference
Viral RNA and evolved mutational robustness
10.1002/(sici)1097-010x(19990815)285:2<119::aid-jez4>3.0.co;2-d · 1999 · External reference
A population genetic theory of canalization
10.1111/j.1558-5646.1997.tb02420.x · 1997 · External reference