Research graph
References from Ehrlichia ruminantium uses its transmembrane protein Ape to adhere to host bovine aortic endothelial cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Natural history of Ehrlichia ruminantium
10.1016/j.vetpar.2009.09.014 · 2010 · External reference
Diverse Functions of Glycosaminoglycans in Infectious Diseases
10.1016/s1877-1173(10)93016-0 · 2010 · External reference
Glycobiology of syndecan-1 in bacterial infections
10.1042/bst20170395 · 2018 · External reference
Proteoglycans in host–pathogen interactions: molecular mechanisms and therapeutic implications
10.1017/s1462399409001367 · 2010 · External reference
Mapping the Subcellular Proteome of Shewanella oneidensis MR-1 using Sarkosyl-Based Fractionation and LC−MS/MS Protein Identification
10.1021/pr100215h · 2010 · External reference
An Entry-Triggering Protein of Ehrlichia Is a New Vaccine Candidate against Tick-Borne Human Monocytic Ehrlichiosis
10.1128/mbio.00895-20 · 2020 · External reference
Recombination Is a Major Driving Force of Genetic Diversity in the Anaplasmataceae Ehrlichia ruminantium
10.3389/fcimb.2016.00111 · 2016 · External reference
Efficient high-throughput molecular method to detect Ehrlichia ruminantium in ticks
10.1186/s13071-017-2490-0 · 2017 · External reference
Regulation of Type IV Secretion Apparatus Genes during Ehrlichia chaffeensis Intracellular Development by a Previously Unidentified Protein
10.1128/jb.01813-07 · 2008 · External reference
Adhesion of outer membrane proteins containing tandem repeats of and species (Rickettsiales: Anaplasmataceae) to tick cells
10.1016/j.vetmic.2003.11.001 · 2004 · External reference
Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells
10.1016/s0378-1135(02)00309-7 · 2003 · External reference
review of heartwater and the threat of introduction of Cowdria ruminantium and Amblyomma spp. ticks to the American mainland
1998 · External reference
The PyMOL Molecular Graphics
External reference
Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila.
10.1099/00207713-51-6-2145 · 2001 · External reference
The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?
10.3390/microorganisms6020039 · 2018 · External reference
Comparative Genomics of Three Strains of Ehrlichia ruminantium
10.1196/annals.1373.061 · 2006 · External reference
Ehrlichia ruminantium: genomic and evolutionary features
10.1016/j.pt.2007.07.007 · 2007 · External reference
Gateway-compatible vectors for high-throughput protein expression in pro- and eukaryotic cell-free systems
10.1016/j.jbiotec.2014.12.006 · 2015 · External reference
Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
10.3389/fmicb.2016.00220 · 2016 · External reference
Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection
10.3389/fcimb.2020.00500 · 2020 · External reference
Anaplasma marginale Outer Membrane Protein A Is an Adhesin That Recognizes Sialylated and Fucosylated Glycans and Functionally Depends on an Essential Binding Domain
10.1128/iai.00968-16 · 2017 · External reference
Intracellular Parasitism by the Human Granulocytic Ehrlichiosis Bacterium Through the P-Selectin Ligand, PSGL-1
10.1126/science.288.5471.1653 · 2000 · External reference
OmpA-mediated rickettsial adherence to and invasion of human endothelial cells is dependent upon interaction with α2β1 integrin
10.1111/cmi.12068 · 2012 · External reference
Synergy between the N- and C-terminal domains of InlB for efficient invasion of non-phagocytic cells by Listeria monocytogenes
10.1046/j.1365-2958.2001.02704.x · 2001 · External reference
Anaplasma phagocytophilum Asp14 Is an Invasin That Interacts with Mammalian Host Cells via Its C Terminus To Facilitate Infection
10.1128/iai.00932-12 · 2013 · External reference
Plasmodium falciparum BAEBL Binds to Heparan Sulfate Proteoglycans on the Human Erythrocyte Surface
10.1074/jbc.m109.021576 · 2010 · External reference
Structural Requirements for Glycosaminoglycan Recognition by the Lyme Disease Spirochete, Borrelia burgdorferi
10.1128/iai.66.12.6045-6048.1998 · 1998 · External reference
Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase
10.1080/15548627.2016.1217369 · 2016 · External reference
Borrelia burgdorferi glycosaminoglycan-binding proteins: a potential target for new therapeutics against Lyme disease
10.1099/mic.0.000571 · 2017 · External reference
Cell surface adherence and endocytosis of protein transduction domains
10.1016/s1525-0016(03)00135-7 · 2003 · External reference
Sweet and Sour Ehrlichia: Glycoproteomics and Phosphoproteomics Reveal New Players in Ehrlichia ruminantium Physiology and Pathogenesis
10.3389/fmicb.2019.00450 · 2019 · External reference
Characterization of Ehrlichia ruminantium replication and release kinetics in endothelial cell cultures
10.1016/j.vetmic.2005.07.012 · 2005 · External reference
Glycosaminoglycans are differentially involved in bacterial binding to healthy and cystic fibrosis lung cells
10.1016/j.jcf.2018.10.017 · 2019 · External reference
Détection d’anticorps contre Cowdria ruminantium; dans le sérum de ruminants domestiques par ELISA indirect
10.19182/remvt.9346 · 1993 · External reference
Identification of OmpA, a Coxiella burnetii Protein Involved in Host Cell Invasion, by Multi-Phenotypic High-Content Screening
10.1371/journal.ppat.1004013 · 2014 · External reference
Ku70, a Component of DNA-Dependent Protein Kinase, Is a Mammalian Receptor for Rickettsia conorii
10.1016/j.cell.2005.08.046 · 2005 · External reference
Escherichia coli Electrotransformation
10.1385/0-89603-310-4:105 · External reference
Ehrlichia chaffeensis Uses Its Surface Protein EtpE to Bind GPI-Anchored Protein DNase X and Trigger Entry into Mammalian Cells
10.1371/journal.ppat.1003666 · 2013 · External reference
Iron Starvation Conditions Upregulate Ehrlichia ruminantium Type IV Secretion System, tr1 Transcription Factor and map1 Genes Family through the Master Regulatory Protein ErxR
10.3389/fcimb.2017.00535 · 2018 · External reference
Proteomic Profiling of the Outer Membrane Fraction of the Obligate Intracellular Bacterial Pathogen Ehrlichia ruminantium
10.1371/journal.pone.0116758 · 2015 · External reference
Ehrlichia's molecular tricks to manipulate their host cells
10.1016/j.micinf.2015.11.001 · 2016 · External reference
Adhesins and invasins of pathogenic bacteria: a structural view
10.1016/j.micinf.2003.11.001 · 2004 · External reference
Searching algorithm for Type IV effector proteins (S4TE) 2.0: Improved tools for Type IV effector prediction, analysis and comparison in proteobacteria
10.1371/journal.pcbi.1006847 · 2019 · External reference
Anaplasma phagocytophilum Outer Membrane Protein A Interacts with Sialylated Glycoproteins To Promote Infection of Mammalian Host Cells
10.1128/iai.00654-12 · 2012 · External reference
Characterization of variable immunodominant antigens of Cowdria ruminantium by ELISA and immunoblots
10.1046/j.1365-3024.1998.00193.x · 1998 · External reference
Bacterial Adhesion and Entry into Host Cells
10.1016/j.cell.2006.02.012 · 2006 · External reference
Global gene expression profiling of Ehrlichia ruminantium at different stages of development
10.1111/j.1574-695x.2011.00901.x · 2012 · External reference
Glycosaminoglycans are involved in bacterial adherence to lung cells
10.1186/s12879-017-2418-5 · 2017 · External reference
Anaplasma phagocytophilum PSGL-1-independent infection does not require Syk and leads to less efficient AnkA delivery
10.1111/j.1462-5822.2008.01168.x · 2008 · External reference
Role and Function of the Type IV Secretion System in Anaplasma and Ehrlichia Species
10.1007/978-3-319-75241-9_12 · 2017 · External reference
Novel Interactions of Glycosaminoglycans and Bacterial Glycolipids Mediate Binding of Enterococci to Human Cells
10.1074/jbc.m901460200 · 2009 · External reference
Ehrlichia chaffeensis and Its Invasin EtpE Block Reactive Oxygen Species Generation by Macrophages in a DNase X-Dependent Manner
10.1128/mbio.01551-17 · 2017 · External reference
Role of heparan sulfate in sexually transmitted infections
10.1093/glycob/cws106 · 2012 · External reference
Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells
10.1111/j.1462-5822.2010.01535.x · 2010 · External reference
SWISS-MODEL: homology modelling of protein structures and complexes
10.1093/nar/gky427 · 2018 · External reference
Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation
10.1073/pnas.1806904115 · 2018 · External reference
I-TASSER server: new development for protein structure and function predictions
10.1093/nar/gkv342 · 2015 · External reference
Prediction of protein subcellular localization
10.1002/prot.21018 · 2006 · External reference
I-TASSER-MTD: a deep-learning-based platform for multi-domain protein structure and function prediction
10.1038/s41596-022-00728-0 · 2022 · External reference