Research graph
References from Cytokine priming shifts mitochondrial architecture and extracellular vesicle cargo of feline placental mesenchymal stromal cells toward an immunosuppressive phenotype. Local targets link to admitted publications; unresolved targets remain external evidence.
A multicenter experience using adipose-derived mesenchymal stem cell therapy for cats with chronic, non-responsive gingivostomatitis
2020 · External reference
Therapeutic efficacy of fresh, autologous mesenchymal stem cells for severe refractory gingivostomatitis in cats
2016 · External reference
Therapeutic efficacy of fresh, allogeneic mesenchymal stem cells for severe refractory feline chronic gingivostomatitis
2017 · External reference
Placenta-derived mesenchymal stromal cells as a treatment for refractory chronic gingivostomatitis in cats: eight cases (2018)
2023 · External reference
Mesenchymal stromal cell therapy for feline chronic gingivostomatitis: long-term experience
2023 · External reference
Clinical field study evaluating the safety and efficacy of allogeneic uterine-derived mesenchymal stem cells for refractory feline chronic gingivostomatitis
2025 · External reference
Mesenchymal stem cell–natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2–induced NK-cell proliferation
2006 · External reference
Histological, immunological, and genetic analysis of feline chronic gingivostomatitis
2020 · External reference
The influence of oral bacteria on tissue levels of toll-like receptor and cytokine mRNAs in feline chronic gingivostomatitis and oral health
2013 · External reference
Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T lymphocyte proliferation
2019 · External reference
Feline adipose-derived mesenchymal stem cells induce effector phenotype and enhance cytolytic function of CD8+ t cells
2021 · External reference
Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome
2017 · External reference
Activated T-cells and pro-inflammatory cytokines differentially regulate prostaglandin E2 secretion by mesenchymal stem cells
2012 · External reference
Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
2009 · External reference
Mesenchymal stem cell–mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
2008 · External reference
Soluble molecules are key in maintaining the immunomodulatory activity of murine mesenchymal stromal cells
2012 · External reference
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
2002 · External reference
Distinctive characteristics of extracellular vesicles from feline adipose and placenta stromal cells unveil potential for regenerative medicine in cats
2024 · External reference
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
2007 · External reference
Immunomodulatory effects of mesenchymal stem cell-derived exosomes on experimental type-1 autoimmune diabetes
2018 · External reference
Regulation of immune responses by extracellular vesicles
2014 · External reference
Shedding light on the cell biology of extracellular vesicles
2018 · External reference
IFN-γ and TNF-α synergistically induce mesenchymal stem cell impairment and tumorigenesis via NF-κB signaling
2013 · External reference
In situ licensing of mesenchymal stem cell immunomodulatory function via BMP-2-induced developmental process
2024 · External reference
Immunomodulatory effect of IFN-γ licensed adipose-mesenchymal stromal cells in an in vitro model of inflammation generated by SARS-CoV-2 antigens
2024 · External reference
The role of TNF-α in the fate regulation and functional reprogramming of mesenchymal stem cells in an inflammatory microenvironment
2023 · External reference
Extracellular vesicles from TNF-α-preconditioned MSCs: effects on immunomodulation and bone regeneration
2022 · External reference
Immune dysfunctionality of replicative senescent mesenchymal stromal cells is corrected by IFN-γ priming
2017 · External reference
Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
2006 · External reference
Impact of pro-inflammatory cytokine preconditioning on metabolism and extracellular vesicles in feline mesenchymal stromal cells: a preliminary study
2025 · External reference
The role of cytokine licensing in shaping the therapeutic potential of Wharton’s jelly MSCs: metabolic shift towards immunomodulation at the expense of differentiation
2025 · External reference
Improving the therapeutic profile of MSCs: cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity
2025 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(−delta delta C(T)) method
2001 · External reference
Simplified evaluation of apoptosis using the muse cell analyzer
2012 · External reference
Minimal criteria for defining multipotent mesenchymal stromal cells: the International Society for Cellular Therapy position statement
2006 · External reference
Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
2006 · External reference
Altered properties of feline adipose-derived mesenchymal stem cells during continuous in vitro cultivation
2018 · External reference
Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction
2015 · External reference
Adipogenic placenta-derived mesenchymal stem cells are not lineage restricted by withdrawing extrinsic factors: developing a novel visual angle in stem cell biology
2016 · External reference
MIT-001 restores human placenta-derived mesenchymal stem cells by enhancing mitochondrial quiescence and cytoskeletal organization
2021 · External reference
Mitochondrial transfer and regulators of mesenchymal stromal cell function and therapeutic efficacy
2020 · External reference
Mitochondrial dynamics in placenta-derived mesenchymal stem cells regulate the invasion activity of trophoblast
2020 · External reference
Human placenta‑derived mesenchymal stem cells induce trophoblast invasion via dynamic effects on mitochondrial function
2021 · External reference
A novel cytoprotective peptide protects mesenchymal stem cells against mitochondrial dysfunction and apoptosis induced by starvation via Nrf2/Sirt3/FoxO3a pathway
2017 · External reference
Mitochondrial fission, fusion, and stress
2012 · External reference
Mitochondrial dynamics and inheritance during cell division, development and disease
2014 · External reference
Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
2015 · External reference
Mitochondrial immunometabolism in sepsis: orchestrating macrophage polarization and dysfunction
2025 · External reference
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
2014 · External reference
A guide to immunometabolism for immunologists
2016 · External reference
Regulation of long-distance transport of mitochondria along microtubules
2018 · External reference
Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors
2021 · External reference
Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX
2018 · External reference
Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation
2018 · External reference
Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS
2021 · External reference
Mesenchymal stem cell–mediated transfer of mitochondria: mechanisms and functional impact
2022 · External reference
Musculoskeletal progenitor/stromal cell-derived mitochondria modulate cell differentiation and therapeutical function
2021 · External reference
Leptin enhances glycolysis via OPA1-mediated mitochondrial fusion to promote mesenchymal stem cell survival
2019 · External reference
Alterations in mitochondrial morphology as a key driver of immunity and host defence
2021 · External reference
Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches
2024 · External reference
The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes
2013 · External reference
B lymphocytes secrete antigen-presenting vesicles
1996 · External reference
Targeting CCR8 induces protective antitumor immunity and enhances vaccine-induced responses in colon cancer
2018 · External reference
Identification of CD112R as a novel checkpoint for human T cells
2016 · External reference
Preconditioning with IFN-γ and LPS improves the immunomodulatory potential of bone marrow-derived clonal mesenchymal stem cells
2023 · External reference
Immunohistochemical characterization of oral mucosal lesions in cats with chronic gingivostomatitis
2011 · External reference
Extracellular histones are major mediators of death in sepsis
2009 · External reference
Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases
2023 · External reference
miR-204 and miR-211 suppress synovial inflammation and proliferation in rheumatoid arthritis by targeting Ssrp1
2022 · External reference
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression
2019 · External reference
The interaction between miRNAs/lncRNAs and nuclear factor-κB (NF-κB) in human disorders
2021 · External reference
Nuclear miR-204-3p mitigates metabolic dysfunction-associated steatotic liver disease in mice
2024 · External reference
MicroRNAs in macrophages: regulators of activation and function
2023 · External reference
miR-181a-1/b-1 modulates tolerance through opposing activities in selection and peripheral T-cell function
2015 · External reference
Transcriptional activation of microRNA-34a by NF-κB in human esophageal cancer cells
2012 · External reference
The microRNA-34a-induced senescence-associated secretory phenotype (SASP) favors vascular smooth muscle cells calcification
2020 · External reference
MiR-320a contributes to atherogenesis by augmenting multiple risk factors and down-regulating SRF
2015 · External reference
Transcriptomic signatures of feline chronic gingivostomatitis are influenced by upregulated IL6
2023 · External reference
Stem cell therapy prior to full-mouth tooth extraction lacks substantial clinical efficacy in cats affected by chronic gingivostomatitis
2021 · External reference
Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
2019 · External reference
Preconditioning influences mesenchymal stem cell properties in vitro and in vivo
2018 · External reference
Mesenchymal stromal cells: clinical challenges and therapeutic opportunities
2018 · External reference
Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization
2018 · External reference
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
2006 · External reference
