Research graph
References from Novel serum biomarkers provide evidence for an involvement of the CCL3:CCL5 axis in fatal musculoskeletal injuries in Thoroughbred racehorses. Local targets link to admitted publications; unresolved targets remain external evidence.
Common lesions of the distal end of the third metacarpal/metatarsal bone in racehorse catastrophic breakdown injuries
2017 · External reference
Can quantitative computed tomography detect bone morphological changes associated with catastrophic proximal sesamoid bone fracture in Thoroughbred racehorses?
2019 · External reference
Noncatastrophic and catastrophic fractures in racing Thoroughbreds at the Hong Kong Jockey Club
2019 · External reference
A radiomics platform for computing imaging features from µCT images of Thoroughbred racehorse proximal sesamoid bones: benchmark performance and evaluation
2021 · External reference
Subchondral focal osteopenia associated with proximal sesamoid bone fracture in Thoroughbred racehorses
2021 · External reference
Race- and course-level risk factors for fatal distal limb fracture in racing Thoroughbreds
2004 · External reference
Reduction of Thoroughbred racing fatalities at New York Racing Association racetracks using a multi-disciplinary mortality review process
2017 · External reference
Longitudinal monitoring of fetlock lesions in Thoroughbred racehorses using standing 18F-sodium fluoride positron emission tomography
2022 · External reference
Comparison of 18F-sodium fluoride positron emission tomography and computed tomography for imaging of the fetlock in 25 nonracehorses
2024 · External reference
Comparison of skeletal scintigraphy and standing 18F-NaF positron emission tomography for imaging of the fetlock in 33 Thoroughbred racehorses
2023 · External reference
Bone biomarkers and risk of fracture in two- and three-year-old Thoroughbreds
2009 · External reference
Serum biomarker levels for musculoskeletal disease in two- and three-year-old racing Thoroughbred horses: a prospective study of 130 horses
2010 · External reference
Concurrent measurement of serum and radiomic biomarkers in the clinical investigation of equine musculoskeletal injuries: a prospective pilot study
2023 · External reference
TNF and bone remodeling
2017 · External reference
Bone degeneration, inflammation and secondary complications of arthritis: potential targets and their natural inhibitors
2018 · External reference
Development of a bead-based multiplex assay for simultaneous quantification of cytokines in horses
2009 · External reference
Analysis of soluble CD14 and its use as a biomarker in neonatal foals with septicemia and horses with recurrent airway obstruction
2013 · External reference
New mAbs facilitate quantification of secreted equine TNF-α and flow cytometric analysis in monocytes and T cells
2021 · External reference
Monoclonal antibodies for equine IL-1β enable the quantification of mature IL-1β in horses
2024 · External reference
Fluorescent bead-based multiplex assays improve serological disease diagnostics and have potential of identifying sensitive immune biomarkers for maintaining health and performance
2025 · External reference
Monoclonal antibody development advances immunological research in horses
2024 · External reference
The deletion of the ORF1 and ORF71 genes reduces virulence of the neuropathogenic EHV-1 strain Ab4 without compromising host immunity in horses
2018 · External reference
Intranasal IgG4/7 antibody responses protect horses against equid herpesvirus-1 (EHV-1) infection including nasal virus shedding and cell-associated viremia
2019 · External reference
An equine herpesvirus type 1 (EHV-1) Ab4 open reading frame 2 deletion mutant provides immunity and protection from EHV-1 infection and disease
2019 · External reference
Horses affected by EPM have increased sCD14 compared to healthy horses
2021 · External reference
Hyaluronic acid synthesis, degradation, and crosslinking in equine osteoarthritis: TNF-α-TSG-6-mediated HC-HA formation
2021 · External reference
Synovial chemokine and cytokine profiles in horses with and without systemic Borrelia burgdorferi infection
2026 · External reference
Inflammatory markers for differentiation of endometritis in the mare
2024 · External reference
Inflammatory marker analysis of uterine cytobrush samples helps identify mares with endometritis
2025 · External reference
Chemokines in physiological and pathological bone remodeling
2019 · External reference
Chemokines and bone
10.1007/164_2020_349 · 2020 · External reference
Physiological bone remodeling: systemic regulation and growth factor involvement
2016 · External reference
Bone regeneration: current concepts and future directions
2011 · External reference
Fractures - a preventable hazard of racing Thoroughbreds?
2002 · External reference
Exercise history predicts focal differences in bone volume fraction, mineral density and microdamage in the proximal sesamoid bones of Thoroughbred racehorses
2022 · External reference
The role of CCL3 in the pathogenesis of rheumatoid arthritis
2023 · External reference
CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss
2017 · External reference
The effect of CCL3 and CCR1 in bone remodeling induced by mechanical loading during orthodontic tooth movement in mice
2013 · External reference
Osteostaticytes: a novel osteoclast subset couples bone resorption and bone formation
2024 · External reference
Association between an increased serum CCL5 level and pathophysiology of degenerative joint disease in the temporomandibular joint in females
2023 · External reference
CCL5/CCR5 axis in human diseases and related treatments
2022 · External reference
Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis
2022 · External reference
Immunohistological staining of unknown chemokine RANTES/CCL5 expression in jawbone marrow defects—osteoimmunology and disruption of bone remodeling in clinical case studies targeting on predictive preventive personalized medicine
2019 · External reference
Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)
2013 · External reference
CCL11, a novel mediator of inflammatory bone resorption
2017 · External reference
Eotaxin-1/CCL11 is involved in cell migration in rheumatoid arthritis
2021 · External reference
Monoclonal antibodies to equine CD14
2010 · External reference
Targeting CD14 to inhibit macrophage senescence and regulate the microenvironment for enhanced tendon-bone healing
2025 · External reference
