Research graph
References from Applying the Zelen design to real-world studies in traditional Chinese medicine: feasibility, ethical considerations, and methodological challenges. Local targets link to admitted publications; unresolved targets remain external evidence.
Exploring the application of Zelen design in real-world studies
2022 · External reference
Revisiting real-world study
2017 · External reference
Method and practice of real world study
2014 · External reference
Pragmatic clinical trials: a randomized trial in real-world studies
2022 · External reference
Real-world study: a potential new approach to effectiveness evaluation of traditional Chinese medicine interventions
10.3736/jcim20100401 · 2010 · External reference
Progress of Zelen’s design and its application value in clinical research
2025 · External reference
Strategies for overcoming enrollment challenges of patients in control group in randomized controlled trials of traditional Chinese medicine
2025 · External reference
Concept and method of randomization in clinical trials
10.3736/jcim20030402 · 2003 · External reference
Zelen design clinical trials: why, when, and how
10.1186/s13063-021-05517-w · 2021 · External reference
A new design for randomized clinical trials
10.1056/nejm197905313002203 · 1979 · External reference
What is Zelen’s design
10.1136/bmj.316.7131.606 · 1998 · External reference
Randomized consent designs for clinical trials: an update
10.1002/sim.4780090611 · 1990 · External reference
Informed consent
10.1136/bmj.315.7102.247 · 1997 · External reference
Nested consent design for clinical trials
10.1093/jjco/28.5.329 · 1998 · External reference
A qualitative study exploring the acceptability of the McNulty-Zelen design for randomized controlled trials evaluating educational interventions
10.1186/s12875-015-0356-0 · 2015 · External reference
Effect of zelen’s Guige Lingxian decoction combined with moxibustion at neck Jiaji acupoint in treatment of cervical spondylotic radiculopathy of wind-cold-dampness arthralgia syndrome
2020 · External reference
Using the Zelen design in randomized controlled trials: debates and controversies
10.1046/j.1365-2648.2002.02164.x · 2002 · External reference
Ethical review measures for ethical review of life science and medical research involving human being
2023 · External reference
10.1093/epirev/24.1.39
10.1093/epirev/24.1.39 · External reference
Identification of causal effects using instrumental variables
10.1080/01621459.1996.10476902 · 1996 · External reference
Effect of a low-intensity PSA-based screening intervention on prostate cancer mortality: the CAP randomized clinical trial
10.1001/jama.2018.0154 · 2018 · External reference
Two-stage residual inclusion estimation: addressing endogeneity in health econometric modeling
10.1016/j.jhealeco.2007.09.009 · 2008 · External reference
A note on G-estimation of causal risk ratios
10.1093/aje/kwx347 · 2018 · External reference
Roderick J
10.1007/s11336-022-09856-8 · 2022 · External reference
Pragmatic trials
10.1056/nejmra1510059 · 2016 · External reference
Rethinking pragmatic randomized controlled trials: introducing the “cohort multiple randomized controlled trial” design
10.1136/bmj.c1066 · 2010 · External reference
Summary and evaluation of clinical research on the treatment of type 2 diabetes mellitus with Chinese patent medicine
2023 · External reference
Analysis and reflection on the literature status of TCM clinical research outcome indicators
2022 · External reference
Traditional Chinese medicine guideline for diagnosis and treatment of chronic heart failure (2022)
10.25236/ijfm.2022.041003 · 2023 · External reference
ACG clinical guideline: ulcerative colitis in adults
10.14309/ajg.0000000000000152 · 2019 · External reference
The introduction and evaluation of patient preference randomized controlled trials
10.1001/jama.294.1.41-a · 2016 · External reference
Design and application of partial randomized clinical trials considering patients’ preferences in effect evaluation of Chinese medicine non-drug therapy
2016 · External reference
Research progress on the application of traditional Chinese health keeping exercise in prevention of falls in elderly
2023 · External reference
