Research graph
References from Walnut green husk polyphenols ameliorate type 2 diabetes in C57BL/6 mice by the gut microbiota and IRS/PI3K/AKT signaling pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
Chlorogenic acid and caffeic acid from Sonchus oleraceus Linn synergistically attenuate insulin resistance and modulate glucose uptake in HepG2 cells
10.1016/j.fct.2019.03.038 · 2019 · External reference
The time is right for a new classification system for diabetes: rationale and implications of the β-cell-centric classification schema
10.2337/dc15-1585 · 2016 · External reference
Hypoglycemic effect of Hypericum attenuatum Choisy extracts on type 2 diabetes by regulating glucolipid metabolism and modulating gut microbiota
10.1016/j.jff.2018.11.031 · 2019 · External reference
Diabesity and antidiabetic drugs
10.1016/j.mam.2018.10.004 · 2019 · External reference
Effects of walnut husk washing waters and their phenolic constituents on horticultural species
10.1007/s11356-012-0847-7 · 2012 · External reference
A comprehensive review on the chemical constituents and functional uses of walnut (Juglans spp.) husk
10.3390/ijms20163920 · 2019 · External reference
Walnut green husk polysaccharides prevent obesity, chronic inflammatory responses, nonalcoholic fatty liver disease, and colonic tissue damage in high-fat diet-fed rats
10.1016/j.ijbiomac.2021.04.047 · 2021 · External reference
Machine learning for synergistic network pharmacology: a comprehensive overview
10.1093/bib/bbad120 · 2023 · External reference
Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula
10.1016/j.jep.2023.116306 · 2023 · External reference
Extraction, in vitro hypoglycaemic activity and active ingredient analysis of polyphenols from walnut green husk
10.1016/j.jff.2024.106508 · 2024 · External reference
Antioxidant activities and polyphenolic identification by UPLC-MS/MS of autoclaved brewers’ spent grain
10.1016/j.lwt.2022.113612 · 2022 · External reference
In vivo antidiabetic and antioxidant potential of Psychotria dalzellii in streptozotocin-induced diabetic rats
10.1016/j.sajb.2018.12.006 · 2019 · External reference
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats
10.1039/d1fo04164a · 2022 · External reference
Mitochondrial damage-associated molecular patterns: a new insight into metabolic inflammation in type 2 diabetes mellitus
10.1002/dmrr.3733 · 2024 · External reference
Lonicera caerulea L. polyphenols improve short-chain fatty acid levels by reshaping the microbial structure of fermented feces in vitro
10.3389/fmicb.2023.1228700 · 2023 · External reference
Fermented dietary fiber from soy sauce residue exerts antidiabetic effects through regulating the PI3K/AKT signaling pathway and gut microbiota-SCFAs-GPRs axis in type 2 diabetic mellitus mice
10.1016/j.ijbiomac.2024.132251 · 2024 · External reference
Recent development in the application of walnut processing by-products (walnut shell and walnut husk)
10.1007/s13399-023-04778-6 · 2023 · External reference
Chemical constituents and antitumor activities of walnut green husk
2019 · External reference
Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
10.3892/ijmm.2018.3554 · 2018 · External reference
Comparison of the effects of Juglans nigra green husk and clotrimazole on Candida albicans in rats
10.5812/jjm.58151 · 2017 · External reference
Alleviating effects of walnut green husk extract on disorders of lipid levels and gut bacteria flora in high fat diet-induced obesity rats
10.1016/j.jff.2018.11.022 · 2019 · External reference
Polyphenols-rich extracts from walnut green husk prevent non-alcoholic fatty liver disease, vascular endothelial dysfunction and colon tissue damage in rats induced by high-fat diet
10.1016/j.jff.2021.104853 · 2021 · External reference
Inhibitory kinetics and mechanism of active compounds in green walnut husk against α-glucosidase: spectroscopy and molecular docking analyses
10.1016/j.lwt.2022.114179 · 2022 · External reference
Food polyphenols and type Ⅱ diabetes mellitus: pharmacology and mechanisms
10.3390/molecules28103996 · 2023 · External reference
Fu brick tea manages HFD/STZ-induced type 2 diabetes by regulating the gut microbiota and activating the IRS1/PI3K/Akt signaling pathway
10.1021/acs.jafc.2c02400 · 2022 · External reference
Targeting AMPK signaling in the liver: implications for obesity and type 2 diabetes mellitus
10.2174/1389450123666220429082702 · 2022 · External reference
Glycolipid metabolism and liver transcriptomic analysis of the therapeutic effects of pressed degreased walnut meal extracts on type 2 diabetes mellitus rats
10.1039/d0fo00670j · 2020 · External reference
Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links
10.2174/1999307011666190618112224 · 2019 · External reference
Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review
10.3389/fimmu.2023.1243834 · 2023 · External reference
Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population
10.1186/s12866-020-01903-7 · 2020 · External reference
Polyphenol extracts from germinated mung beans can improve type 2 diabetes in mice by regulating intestinal microflora and inhibiting inflammation
10.3389/fnut.2022.846409 · 2022 · External reference
Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota
10.1038/s41467-022-32015-7 · 2022 · External reference
Multiomics analyses with stool-type stratification in patient cohorts and Blautia identification as a potential bacterial modulator in type 2 diabetes mellitus
10.2337/db23-0447 · 2024 · External reference
Role of gut microbiota in type 2 diabetes pathophysiology
10.1016/j.ebiom.2019.11.051 · 2020 · External reference
Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in ice with high-fat-diet induced obesity
10.1371/journal.pone.0041079 · 2012 · External reference
Review of literature on Akkermansia muciniphila and its possible role in the etiopathogenesis and therapy of type 2 diabetes mellitus
10.15605/jafes.037.01.13 · 2022 · External reference
Regulation of hepatic glucose metabolism in health and disease
10.1038/nrendo.2017.80 · 2017 · External reference
Green coffee extract improves cardiometabolic parameters and modulates gut microbiota in high-fat-diet-fed ApoE-/- mice
10.3390/nu11030497 · 2019 · External reference
Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance in vitro and in vivo
10.7150/ijbs.80125 · 2023 · External reference
Effect of Codonopsis Radix and Polygonati Rhizoma on the regulation of the IRS1/PI3K/AKT signaling pathway in type 2 diabetic mice
10.3389/fendo.2022.1068555 · 2022 · External reference
