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References from Application of multi-omics to reveal the protective mechanism of <i>Portulaca oleracea</i> ethanol extract against alcoholic liver disease in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
The liver
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Alcohol control policy and changes in alcohol-related traffic harm
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A review of traditional uses, phytochemistry and pharmacology of Portulaca oleracea L
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Evaluation of antioxidant compounds, antioxidant activities, and mineral composition of 13 collected purslane (Portulaca oleracea L.) accessions
10.1155/2014/296063 · 2014 · External reference
Phenolic compound profile of selected vegetables frequently consumed by African Americans in the southeast United States
10.1016/j.foodchem.2006.10.077 · 2007 · External reference
Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
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HM-chromanone suppresses hepatic glucose production via activation of AMP-activated protein kinase in HepG2 cell
10.1016/j.ejphar.2022.175108 · 2022 · External reference
Purslane extract and glucose homeostasis in adults with type 2 diabetes: a double-blind, placebo-controlled clinical trial of efficacy and safety
10.1089/jmf.2015.0090 · 2016 · External reference
Portulaca oleracea reduces triglyceridemia, cholesterolemia, and improves lecithin: cholesterol acyltransferase activity in rats fed enriched-cholesterol diet
10.1016/j.phymed.2014.07.010 · 2014 · External reference
Evaluation of the gastric antiulcerogenic effects of Portulaca oleracea L. extracts in mice
10.1002/ptr.1463 · 2004 · External reference
Protective effects of ethanol extract from Portulaca oleracea L on dextran sulphate sodium-induced mice ulcerative colitis involving anti-inflammatory and antioxidant
2016 · External reference
The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. Sativa (Haw.) Celak
10.1016/s0378-8741(00)00318-4 · 2000 · External reference
Detection of antifungal activity in Portulaca oleracea by a single-cell bioassay system
10.1002/1099-1573(200008)14:5<329::aid-ptr581>3.0.co;2-5 · 2000 · External reference
Antiviral activity of Portulaca oleracea L. against influenza A viruses
10.1016/j.jep.2019.112013 · 2019 · External reference
Portulaca oleracea seed oil exerts cytotoxic effects on human liver cancer (HepG2) and human lung cancer (A-549) cell lines
10.7314/apjcp.2015.16.8.3383 · 2015 · External reference
Antiulcerogenic effect of ethanolic extract of Portulaca oleracea experimental study
2010 · External reference
The therapeutic effects of Portulaca oleracea L. in hepatogastric disorders
10.1016/j.gastrohep.2018.07.016 · 2019 · External reference
Extracts of Portulaca oleracea promote wound healing by enhancing angiology regeneration and inhibiting iron accumulation in mice
10.1016/j.chmed.2021.09.014 · 2022 · External reference
Effects of hydroalcoholic extracts of Portulaca pilosa and Achyrocline satureioides on urinary sodium and potassium excretion
10.1016/0378-8741(94)90040-x · 1994 · External reference
Ameliorative effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: a review
10.1016/j.jep.2022.115672 · 2022 · External reference
In vitro cytotoxic and antiproliferative effects of Portulaca oleracea methanol extract on breast, cervical, colon and nasopharyngeal cancerous cell lines
10.11158/saa.10.1.7 · 2013 · External reference
Comparison of various solvent extracts and major bioactive components from Portulaca oleracea for antioxidant, anti-tyrosinase, and anti-α-glucosidase activities
10.3390/antiox11020398 · 2022 · External reference
Nanocarrier-mediated antioxidant delivery for liver diseases
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Oxidative stress as a crucial factor in liver diseases
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Cytotoxicity assessments of Portulaca oleracea and Petroselinum sativum seed extracts on human hepatocellular carcinoma cells (HepG2)
10.7314/apjcp.2014.15.16.6633 · 2014 · External reference
Antihepatocarcinoma effect of Portulaca oleracea L. in mice by PI3K/Akt/mTOR and Nrf2/HO-1/NF-κB pathway
10.1155/2017/8231358 · 2017 · External reference
Ethanol extract from Portulaca oleracea L. attenuated acetaminophen-induced mice liver injury
2015 · External reference
Ethanol extract of Portulaca oleracea L. reduced the carbon tetrachloride induced liver injury in mice involving enhancement of NF-κB activity
2014 · External reference
Effects of Portulaca oleracea extract on acute alcoholic liver injury of rats
10.3390/molecules24162887 · 2019 · External reference
Sea buckthorn (Hippophae rhamnoides L.) fermentation liquid protects against alcoholic liver disease linked to regulation of liver metabolome and the abundance of gut microbiota
10.1002/jsfa.10915 · 2020 · External reference
Camel milk modulates ethanol-induced changes in the gut microbiome and transcriptome in a mouse model of acute alcoholic liver disease
10.3168/jds.2019-17247 · 2020 · External reference
Animal models for liver disease – a practical approach for translational research
10.1016/j.jhep.2020.04.011 · 2020 · External reference
Portulaca oleracea alleviates CCl4-induced acute liver injury by regulating hepatic S100A8 and S100A9
10.1016/j.chmed.2022.05.004 · 2023 · External reference
Loss of RAGE prevents chronic intermittent hypoxia-induced nonalcoholic fatty liver disease via blockade of NF-κB pathway
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The role of glyoxalase-Ⅰ (Glo-Ⅰ), advanced glycation endproducts (AGEs), and their receptor (RAGE) in chronic liver disease and hepatocellular carcinoma (HCC)
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A review on bioactive phytochemicals and ethnopharmacological potential of purslane (Portulaca oleracea L.)
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Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase-3- and caspase-9-dependent mitochondrial signaling pathway
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Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome
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Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway
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A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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On the dependency of cellular protein levels on mRNA abundance
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Membranes as the third genetic code
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Ferroptosis in life: to be or not to be
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Assessment of the biological activities of egyptian Purslane (Portulaca oleracea) extract after incorporating metal nanoparticles, in vitro and in vivo study
10.31557/apjcp.2022.23.1.287 · 2022 · External reference
Natural alcohol exposure: is ethanol the main substrate for alcohol dehydrogenases in animals?
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High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking
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Chronic alcohol consumption disrupted cholesterol homeostasis in rats: down-regulation of low-density lipoprotein receptor and enhancement of cholesterol biosynthesis pathway in the liver
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Structure, function and metabolism of hepatic and adipose tissue lipid droplets: implications in alcoholic liver disease
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Purpurin ameliorates alcohol-induced hepatotoxicity by reducing ROS generation and promoting Nrf2 expression
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Lipid peroxidation and iron metabolism: two corner stones in the homeostasis control of ferroptosis
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Identification of ACSL4 as a biomarker and contributor of ferroptosis
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G protein-coupled receptor 35 attenuates nonalcoholic steatohepatitis by reprogramming cholesterol homeostasis in hepatocytes
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Ferroptosis in liver disease: new insights into disease mechanisms
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Iron accumulation in alcoholic liver diseases
10.1097/01.alc.0000189274.00479.62 · 2006 · External reference
Effects of Portulaca oleracea L. seeds in treatment of type-2 diabetes mellitus patients as adjunctive and alternative therapy
10.1016/j.jep.2011.06.020 · 2011 · External reference
The clinical effects of purslane (Portulaca oleracea) seeds on metabolic profiles in patients with nonalcoholic fatty liver disease: a randomized controlled clinical trial
10.1002/ptr.6342 · 2019 · External reference
The effect of purslane seeds on fasting blood glucose and serum liver enzymes in patients with nonalcoholic fatty livers
2015 · External reference
Effect of Portulaca oleracea (purslane) extract on liver enzymes, lipid profile, and glycemic status in nonalcoholic fatty liver disease: a randomized, double-blind clinical trial
10.1002/ptr.6972 · 2021 · External reference
Effect of Portulaca oleracea L. extract on functional constipation
10.4103/sjg.sjg_400_21 · 2022 · External reference
The effects of Portulaca supplementation on antioxidant biomarkers and oxidative stress in non-active girls
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Effect of purslane on blood lipids and glucose: a systematic review and meta-analysis of randomized controlled trials
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