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References from Anti-tumor immune effect of ginseng glucosyl oleanolate transformed from ginsenoside Ro by activating the cGAS/STING pathway and regulating gut microbiota in cervical cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Ginseng: a dietary supplement as immune-modulator in various diseases
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Rare ginsenosides: a unique perspective of ginseng research
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Review of probiotics, gut microorganisms, and their enzymes involved in the conversion of ginsenosides
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Cervical cancer immunotherapy: facts and hopes
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Immunotherapy in cervical cancer
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Ginsenosides are active ingredients in Panax ginseng with immunomodulatory properties from cellular to organismal levels
10.1016/j.jgr.2021.12.007 · 2022 · External reference
New insight into 20(S)-ginsenoside Rh2 against T-cell acute lymphoblastic leukemia associated with the gut microbiota and the immune system
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Ginseng glucosyl oleanolate from ginsenoside Ro, exhibited anti-liver cancer activities via MAPKs and gut microbiota in vitro/vivo
10.1021/acs.jafc.3c08150 · 2024 · External reference
Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis
10.1016/j.phymed.2024.156271 · 2025 · External reference
Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway
10.1038/s41538-024-00341-3 · 2024 · External reference
Ginsenosides in cancer: proliferation, metastasis, and drug resistance
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Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in ApcMin/+ mice
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Influence of icariin on inflammation, apoptosis, invasion, and tumor immunity in cervical cancer by reducing the TLR4/MyD88/NF-κB and Wnt/β-catenin pathways
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Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
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Critical role of the gut microbiota in immune responses and cancer immunotherapy
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Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation
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Therapeutic vaccine targeting dual immune checkpoints induces potent multifunctional CD8+ T cell anti-tumor immunity
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Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients
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Chitosan-based nano-micelles for potential anti-tumor immunotherapy: synergistic effect of cGAS-STING signaling pathway activation and tumor antigen absorption
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Lovastatin/SN38 co-loaded liposomes amplified ICB therapeutic effect via remodeling the immunologically-cold colon tumor and synergized stimulation of cGAS-STING pathway
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Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site
10.1007/s00262-017-1975-1 · 2017 · External reference
Targeting STING in cancer: challenges and emerging opportunities
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STING promotes homeostasis via regulation of cell proliferation and chromosomal stability
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The causal correlation between gut microbiota abundance and pathogenesis of cervical cancer: a bidirectional mendelian randomization study
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Targeting the gut microbiota for cancer therapy
10.1038/s41568-022-00513-x · 2022 · External reference
Gut microbial diversity and genus-level differences identified in cervical cancer patients versus healthy controls
10.1016/j.ygyno.2019.09.002 · 2019 · External reference
Gut microbiota and gynecological cancers: a summary of pathogenetic mechanisms and future directions
10.1021/acsinfecdis.0c00839 · 2021 · External reference
PI3K-CCL2-CCR2-MDSCs axis: a potential pathway for tumor Clostridia-promoted CD 8+ T lymphocyte infiltration in bile tract cancers
10.1016/j.neo.2023.100920 · 2023 · External reference
Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance
10.1016/j.chom.2023.01.013 · 2023 · External reference
Ginsenoside Rg3 enriches SCFA-producing commensal bacteria to confer protection against enteric viral infection via the cGAS-STING-type I IFN axis
10.1038/s41396-023-01541-7 · 2023 · External reference
Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells
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Risks associated with enterococci as probiotics
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10.1158/2159-8290.cd-rw2021-143
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Upregulation of Lactobacillus spp. in gut microbiota as a novel mechanism for environmental eustress-induced anti-pancreatic cancer effects
10.1080/19490976.2025.2470372 · 2025 · External reference
Lactobacillus intestinalis facilitates tumor-derived CCL5 to recruit dendritic cell and suppress colorectal tumorigenesis
10.1080/19490976.2024.2449111 · 2025 · External reference
Microbiota and cytokine modulation: innovations in enhancing anticancer immunity and personalized cancer therapies
10.3390/biomedicines12122776 · 2024 · External reference
Individual strains of Lactobacillus paracasei differentially inhibit human basophil and mouse mast cell activation
10.1002/iid3.113 · 2016 · External reference
Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor 2-dependent and independent mechanisms
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Gut Lactobacillus contribute to the progression of breast cancer by affecting the anti-tumor activities of immune cells in the TME of tumor-bearing mice
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Estrogen and ERα: culprits in cervical cancer?
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Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepatocellular carcinoma via STING signaling
10.1080/19490976.2022.2119055 · 2022 · External reference
The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
10.1016/j.immuni.2022.04.006 · 2022 · External reference
The Immunomodulatory potential of short-chain fatty acids in multiple sclerosis
10.3390/ijms25063198 · 2024 · External reference
Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway
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B. thetaiotaomicron-derived acetic acid modulate immune microenvironment and tumor growth in hepatocellular carcinoma
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Human gut bacteria as potent class I histone deacetylase inhibitors in vitro through production of butyric acid and valeric acid
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Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine
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