Research graph
References from 6-Shogaol alleviates high-fat diet-induced intestinal tight junction impairment in mice <i>via</i> miR-215-3p_R+1/occludin axis. Local targets link to admitted publications; unresolved targets remain external evidence.
Regulation of intestinal barrier function by microbial metabolites
10.1016/j.jcmgh.2021.02.007 · 2021 · External reference
Intestinal barrier function in gluten-related disorders
10.3390/nu11102325 · 2019 · External reference
Paracellular permeability and tight junction regulation in gut health and disease
10.1038/s41575-023-00766-3 · 2023 · External reference
High fat diet, gut microbiome and gastrointestinal cancer
10.7150/thno.56157 · 2021 · External reference
Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction
10.3945/ajcn.116.131110 · 2017 · External reference
High-fat diet impairs gut barrier through intestinal microbiota-derived reactive oxygen species
10.1007/s11427-022-2283-4 · 2024 · External reference
Short-chain fatty acids manifest stimulative and protective effects on intestinal barrier function through the inhibition of NLRP3 inflammasome and autophagy
10.1159/000492853 · 2018 · External reference
Dietary supplementation with glycine enhances intestinal mucosal integrity and ameliorates inflammation in C57BL/6J mice with high-fat diet-induced obesity
10.1093/jn/nxab058 · 2021 · External reference
Effects of high-fat diet exposure on learning & memory
10.1016/j.physbeh.2015.06.008 · 2015 · External reference
Resveratrol attenuates intestinal epithelial barrier dysfunction via Nrf2/HO-1 pathway in dextran sulfate sodium-induced Caco-2 cells
10.1002/iid3.1193 · 2024 · External reference
Cranberry polyphenols and prevention against urinary tract infections: new findings related to the integrity and functionality of intestinal and urinary barriers
10.1021/acs.jafc.3c07169 · 2024 · External reference
Integrated network pharmacology and cellular assay for the investigation of an anti-obesity effect of 6-shogaol
10.1016/j.foodchem.2021.131755 · 2022 · External reference
Benefits of ginger and its constituent 6-shogaol in inhibiting inflammatory processes
10.3390/ph14060571 · 2021 · External reference
Effects of 6-shogaol on glucose uptake and intestinal barrier integrity in Caco-2 cells
10.3390/foods12030503 · 2023 · External reference
6-Shogaol ameliorates injury to the intestinal mucosa and increases survival after high-dose abdominal irradiation
10.1016/j.jff.2017.06.054 · 2017 · External reference
6-Shogaol from dried ginger protects against intestinal ischemia/reperfusion by inhibiting cell apoptosis via the BDNF/TrkB/PI3K/AKT pathway
10.1002/mnfr.202200773 · 2023 · External reference
The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling
10.1002/mnfr.201600274 · 2016 · External reference
MicroRNAs as novel molecular targets of green tea polyphenol epigallocatechin-3-gallate (EGCG): relevance and importance to nutrition sciences and cancer prevention
10.26599/fshw.2024.9250317 · 2025 · External reference
Role of microRNAs in regulation of insulin secretion and insulin signaling involved in type 2 diabetes mellitus
10.1007/s12038-022-00295-2 · 2022 · External reference
MiR-107-3p/Atp6v0e1 contributes to protective effects of two selenium-containing peptides, TSeMMM and SeMDPGQQ on lead-induced neurotoxicity
10.26599/fshw.2022.9250171 · 2024 · External reference
microRNAs in action: biogenesis, function and regulation
10.1038/s41576-023-00611-y · 2023 · External reference
MicroRNA-specific therapeutic targets and biomarkers of apoptosis following myocardial ischemia-reperfusion injury
10.1007/s11010-023-04876-z · 2024 · External reference
Attenuation of palmitic acid-induced intestinal epithelial barrier dysfunction by 6-shogaol in Caco-2 cells: the role of miR-216a-5p/TLR4/NF-κB axis
10.3390/metabo12111028 · 2022 · External reference
6-Shogaol alleviates high-fat diet induced hepatic steatosis through miR-3066-5p/Grem2 pathway
10.1016/j.foodchem.2024.140197 · 2024 · External reference
Metabonomics and the gut microbiome analysis of the effect of 6-shogaol on improving obesity
10.1016/j.foodchem.2022.134734 · 2023 · External reference
6-Paradol and 6-shogaol, the pungent compounds of ginger, promote glucose utilization in adipocytes and myotubes, and 6-paradol reduces blood glucose in high-fat diet-fed mice
10.3390/ijms18010168 · 2017 · External reference
Sesamin is an effective spleen tyrosine kinase inhibitor against IgE-mediated food allergy in computational, cell-based and animal studies
10.26599/fshw.2024.9250081 · 2025 · External reference
Oral delivery of nanoparticles loaded with ginger active compound, 6-shogaol, attenuates ulcerative colitis and promotes wound healing in a murine model of ulcerative colitis
10.1093/ecco-jcc/jjx115 · 2018 · External reference
6-Shogaol, an active ingredient of ginger, improves intestinal and brain abnormalities in proteus mirabilis-induced Parkinson’s disease mouse model
10.4062/biomolther.2023.098 · 2023 · External reference
Interindividual variability in metabolism of[6]-shogaol by gut microbiota
10.1021/acs.jafc.7b02850 · 2017 · External reference
IL1B increases intestinal tight junction permeability by up-regulation of MIR200C-3p, which degrades Occludin mRNA
10.1053/j.gastro.2020.06.038 · 2020 · External reference
Anti-colon cancer effects of 6-shogaol through G2/M cell cycle arrest by p53/p21-cdc2/cdc25A crosstalk
10.1142/s0192415x15500469 · 2015 · External reference
MicroRNA-based diagnosis and therapy
10.3390/ijms23137167 · 2022 · External reference
Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival
10.1111/nyas.14798 · 2022 · External reference
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice
10.1016/j.biopha.2020.110937 · 2021 · External reference
Effect of sodium alginate-based hydrogel loaded with lutein on gut microbiota and inflammatory response in DSS-induced colitis mice
10.1016/j.fshw.2023.03.010 · 2023 · External reference
MiR-144 increases intestinal permeability in IBS-D rats by targeting OCLN and ZO1
10.1159/000486059 · 2017 · External reference
LncRNA ALDB-898 modulates intestinal epithelial cell damage caused by Clostridium perfringens type C in piglet by regulating ssc-miR-122–5p/OCLN signaling
10.1016/j.molimm.2022.07.002 · 2022 · External reference
