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References from Antibiotic-sensitive gut symbiont <i>Turicibacter sanguinis</i> alleviates constipation by enhancing short-chain fatty acids and tryptophan metabolism. Local targets link to admitted publications; unresolved targets remain external evidence.
Dietary lipids, gut microbiota and lipid metabolism
10.1007/s11154-019-09512-0 · 2019 · External reference
Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism
10.1016/j.cmet.2016.05.005 · 2016 · External reference
The central nervous system and the gut microbiome
10.1016/j.cell.2016.10.027 · 2016 · External reference
Interactions between the microbiota, immune and nervous systems in health and disease
10.1038/nn.4476 · 2017 · External reference
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism
10.1096/fj.10.164921 · 2010 · External reference
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
10.1073/pnas.0812874106 · 2009 · External reference
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis
10.1016/j.cell.2015.02.047 · 2015 · External reference
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
10.1073/pnas.0804812105 · 2008 · External reference
Drosophila perpetuates nutritional mutualism by promoting the fitness of its intestinal symbiont Lactobacillus plantarum
10.1016/j.cmet.2017.11.011 · 2018 · External reference
Identifying keystone species in microbial communities using deep learning
10.1038/s41559-023-02250-2 · 2024 · External reference
Gut microbiota Turicibacter strains differentially modify bile acids and host lipids
10.1038/s41467-023-39403-7 · 2023 · External reference
Structural and quantitative alterations of gut microbiota in experimental small bowel obstruction
10.1371/journal.pone.0255651 · 2021 · External reference
Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation
10.1038/nature17645 · 2016 · External reference
The gut microbiota of rural papua new guineans: composition, diversity patterns, and ecological processes
10.1016/j.celrep.2015.03.049 · 2015 · External reference
Multi-trajectories of BMI, waist circumference, gut microbiota, and incident dyslipidemia: a 27-year prospective study
10.1128/msystems.00243-25 · 2025 · External reference
Fecal microbiota signatures are not consistently related to symptom severity in irritable bowel syndrome
10.1007/s10620-022-07543-3 · 2022 · External reference
Fecal microbiota characteristics in constipation-predominant and mixed-type irritable bowel syndrome
10.3390/microorganisms12071414 · 2024 · External reference
An integrated gut microbiota and network pharmacology study on fuzi-lizhong pill for treating diarrhea-predominant irritable bowel syndrome
10.3389/fphar.2021.746923 · 2021 · External reference
Effects of lipid extract from blue mussel (Mytilus edulis) on gut microbiota, and its relationship with glycemic traits in type 2 diabetes mellitus patients: a double-blind randomized controlled trial
10.1039/d3fo01491f · 2023 · External reference
T cell-mediated regulation of the microbiota protects against obesity
10.1126/science.aat9351 · 2019 · External reference
Association of the gut microbiota with weight-loss response within a retail weight-management program
10.3390/microorganisms8081246 · 2020 · External reference
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation
10.1016/j.chom.2023.10.011 · 2023 · External reference
Bowel disorders
10.1053/j.gastro.2016.02.031 · 2016 · External reference
Global prevalence of functional constipation according to the Rome criteria: a systematic review and meta-analysis
10.1016/s2468-1253(21)00111-4 · 2021 · External reference
Constipation and risk of death and cardiovascular events
10.1016/j.atherosclerosis.2018.12.021 · 2019 · External reference
Medical records documentation of constipation preceding Parkinson disease: a case-control study
10.1212/wnl.0b013e3181c34af5 · 2009 · External reference
Relationship between depression and constipation: results from a large cross-sectional study in adults
10.4166/kjg.2022.038 · 2022 · External reference
Association of maternal report of infant and toddler gastrointestinal symptoms with autism: evidence from a prospective birth cohort
10.1001/jamapsychiatry.2014.3034 · 2015 · External reference
Association between constipation and colorectal cancer: systematic review and meta-analysis of observational studies
10.1038/ajg.2013.52 · 2013 · External reference
Gut microbiota-produced tryptamine activates an epithelial G-protein-coupled receptor to increase colonic secretion
10.1016/j.chom.2018.05.004 · 2018 · External reference
Longitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome
10.1016/j.cell.2020.08.007 · 2020 · External reference
Antipsychotic-induced gastrointestinal hypomotility and the alteration in gut microbiota in patients with schizophrenia
10.1016/j.bbi.2021.09.014 · 2022 · External reference
Diet and gut microbial associations in irritable bowel syndrome according to disease subtype
10.1080/19490976.2023.2262130 · 2023 · External reference
Characteristics of the gut microbiota of patients with dyspepsia
10.29296/24999490-2025-03-11 · 2025 · External reference
Antibiotics-induced depletion of mice microbiota induces changes in host serotonin biosynthesis and intestinal motility
10.1186/s12967-016-1105-4 · 2017 · External reference
Amitriptyline at low-dose and titrated for irritable bowel syndrome as second-line treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial
10.1016/s0140-6736(23)01523-4 · 2023 · External reference
Antibiotic perturbations to the gut microbiome
10.1038/s41579-023-00933-y · 2023 · External reference
Antibiotics promote inflammation through the translocation of native commensal colonic bacteria
10.1038/s41579-023-00933-y · 2016 · External reference
A predictive index for health status using species-level gut microbiome profiling
10.1038/s41467-020-18476-8 · 2020 · External reference
Lactiplantibacillus plantarum P9 for chronic diarrhea in young adults: a large double-blind, randomized, placebo-controlled trial
10.1038/s41467-024-51094-2 · 2024 · External reference
Exploring a microbiota-targeted dietary strategy for irritable bowel syndrome
10.1038/s41579-023-00933-y · 2025 · External reference
Gut microbial genomes with paired isolates from China illustrate probiotic and cardiometabolic effects
10.1016/j.xgen.2024.100559 · 2024 · External reference
MetaPhlAn2 for enhanced metagenomic taxonomic profiling
10.1038/nmeth.3589 · 2015 · External reference
Species-level functional profiling of metagenomes and metatranscriptomes
10.1038/s41592-018-0176-y · 2018 · External reference
The gut microbiota in prediabetes and diabetes: a population-based cross-sectional study
10.1016/j.cmet.2020.06.011 · 2020 · External reference
Human reference gut microbiome catalog including newly assembled genomes from under-represented Asian metagenomes
10.1186/s13073-021-00950-7 · 2021 · External reference
Genetic determinants of the gut microbiome in UK twins
10.1016/j.chom.2016.04.017 · 2016 · External reference
Antibiotic use and the development of inflammatory bowel disease: a national case-control study in Sweden
10.1016/s2468-1253(20)30267-3 · 2020 · External reference
The individual response to antibiotics and diet—insights into gut microbial resilience and host metabolism
10.1038/s41574-024-00966-0 · 2024 · External reference
Antibiotics in the pathogenesis of diabetes and inflammatory diseases of the gastrointestinal tract
10.1038/s41575-022-00685-9 · 2023 · External reference
Fecal microbiota alterations associated with diarrhea-predominant irritable bowel syndrome
10.3389/fmicb.2018.01600 · 2018 · External reference
Multi-omics analyses demonstrate the modulating role of gut microbiota on the associations of unbalanced dietary intake with gastrointestinal symptoms in children with autism spectrum disorder
10.1080/19490976.2023.2281350 · 2023 · External reference
Gut microbiota-mediated polyphenol metabolism is restrained by parasitic whipworm infection and associated with altered immune function in mice
10.1080/19490976.2024.2370917 · 2024 · External reference
Studies on nutritional intervention of rice starch-oleic acid complex (resistant starch type V) in rats fed by high-fat diet
10.1016/j.carbpol.2020.116637 · 2020 · External reference
Lactobacillus rhamnosus LRa05 alleviates constipation via triaxial modulation of gut motility, microbiota dynamics, and SCFA metabolism
10.3390/foods14132293 · 2025 · External reference
Multi-strain probiotics alleviate loperamide-induced constipation by adjusting the microbiome, serotonin, and short-chain fatty acids in rats
10.3389/fmicb.2023.1174968 · 2023 · External reference
Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions
2008 · External reference
Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats
10.1053/j.gastro.2010.01.053 · 2010 · External reference
From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites
10.1016/j.cell.2016.05.041 · 2016 · External reference
Multi-omics profiles of the intestinal microbiome in irritable bowel syndrome and its bowel habit subtypes
10.1186/s40168-022-01450-5 · 2023 · External reference
Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial
10.1080/19490976.2023.2197837 · 2023 · External reference
Prevention of loperamide induced constipation in mice by KGM and the mechanisms of different gastrointestinal tract microbiota regulation
10.1016/j.carbpol.2020.117418 · 2021 · External reference
Effects of serotonin on intestinal secretion and motility
10.1097/00001574-200103000-00001 · 2001 · External reference
Effects of serotonin and slow-release 5-hydroxytryptophan on gastrointestinal motility in a mouse model of depression
10.1053/j.gastro.2019.04.022 · 2019 · External reference
Efficacy of a postbiotic and its components in promoting colonic transit and alleviating chronic constipation in humans and mice
10.1016/j.xcrm.2025.102093 · 2025 · External reference
The gammadelta IEL effector API5 masks genetic susceptibility to Paneth cell death
10.1038/s41586-022-05259-y · 2022 · External reference
Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection
10.1016/j.cell.2022.09.024 · 2022 · External reference
Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine
10.1038/s41598-017-10835-8 · 2017 · External reference
Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut
10.1038/s41564-019-0540-4 · 2019 · External reference
Turicibacter fermentation enhances the inhibitory effects of Antrodia camphorata supplementation on tumorigenic serotonin and Wnt pathways and promotes ROS-mediated apoptosis of Caco-2 cells
10.3389/fphar.2023.1203087 · 2023 · External reference
Intestinal epithelial serotonin as a novel target for treating disorders of gut-brain interaction and mood
10.1053/j.gastro.2024.11.012 · 2025 · External reference
Lactobacillus paracasei relieves constipation by acting on the acetic acid-5-HT-intestinal motility pathway
10.3390/foods12224176 · 2023 · External reference
Engineered 5-HT producing gut probiotic improves gastrointestinal motility and behavior disorder
10.3389/fcimb.2022.1013952 · 2022 · External reference
The association between dietary vitamin B1 intake and constipation: a population-based study
10.1186/s12876-024-03255-2 · 2024 · External reference
Constipation in patients with thiamine deficiency after Roux-en-Y gastric bypass surgery
10.1159/000353245 · 2013 · External reference
Association of B vitamins with chronic constipation and diarrhea: a cross-sectional study based on data from NHANES
10.16016/j.2097-0927.202405066 · 2024 · External reference
Exploring the interplay between running exercises, microbial diversity, and tryptophan metabolism along the microbiota-gut-brain axis
10.3389/fmicb.2024.1326584 · 2024 · External reference
Synthesis of serotonin by a second tryptophan hydroxylase isoform
10.1126/science.1078197 · 2003 · External reference
Effect of thiamine deficiency on brain serotonin turnover
10.1016/0006-8993(79)90494-3 · 1979 · External reference
Changes in tryptophan metabolism on serotonin and kynurenine pathways in patients with irritable bowel syndrome
10.3390/nu15051262 · 2023 · External reference
A low FODMAP diet supplemented with L-tryptophan reduces the symptoms of functional constipation in elderly patients
10.3390/nu16071027 · 2024 · External reference
Enteric microbiota-mediated serotonergic signaling in pathogenesis of irritable bowel syndrome
10.3390/ijms221910235 · 2021 · External reference
