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References from Current advances in the bioactivity, biosynthesis, and production enhancement strategies of 5-methyltetrahydrofolate from <i>Moringa oleracea</i> Lam.: a comprehensive review. Local targets link to admitted publications; unresolved targets remain external evidence.
The composition and contents of folates in mature breast milks from six regions of China
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Ranscriptomic analysis of fetal brain induced by low folate and retinoic acid in NTDS mouse model
10.13865/j.cnki.cjbmb.2024.04.1011 · 2024 · External reference
Comparison of red blood cell folate and serum folate in clinical disease outcome
10.16689/j.cnki.cn11-9349/r.2024.01.020 · 2024 · External reference
5, 10-Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms in patients with nonsyndromic cleft lip and palate
10.3892/br.2020.1364 · 2020 · External reference
Expose to high doses of folic acid during pregnancy causes adolescent anxiety- and depression-like behaviors in offspring mice
10.1016/j.jad.2024.09.105 · 2025 · External reference
Folic acid-targeted redox responsive polylactic acid-based nanoparticles co-delivering pirarubicin and salinomycin suppress breast cancer tumor growth in vivo
10.1039/d4nr02365j · 2024 · External reference
Biological characteristics and application of folic acid and 5-methyltetrahydrofolate
10.19804/j.issn1006-2513.2022.02.030 · 2022 · External reference
New perspectives on folic acid supplementation
2009 · External reference
Natural variation analysis of folate components in soybean seeds and identification of candidate genes
2023 · External reference
The relationship between dietary folate and related vitamins intake during pregnancies and folate metabolism levels in umbilical cord blood of neonates
10.13325/j.cnki.acta.nutr.sin.2024.06.002 · 2024 · External reference
Optimization of extraction process for 5-methyltetrahydrofolate from maize and determination of its content by HPLC
10.3724/sp.j.1123.2020.00186 · 2020 · External reference
Development of Moringa oleifera walnut milk and its effect on sleep improvement in mice
10.12161/j.issn.1005-6521.2024.20.012 · 2024 · External reference
Tudy on the mixed silage effect of moringa and sorghum-sudangrass hybrid
10.11829/j.issn.1001-0629.2023-0194 · 2024 · External reference
Development status and thinking of the domestic and international moringa industry
10.13856/j.cn11-1097/s.2015.05.027 · 2015 · External reference
Research progress on bioactive functions and biosynthesis of isothiocyanates
10.13982/j.mfst.1673-9078.2025.7.0482 · 2025 · External reference
Optimization of extraction process of oligosaccharides from Moringa oleifera leaf by response surface methodology
10.3969/j.issn.0517-6611.2023.18.040 · 2023 · External reference
Preliminary transcriptome analysis of folate synthesis and metabolism in cabbage
10.16420/j.issn.0513-353x.2025-0045 · 2025 · External reference
Spinach is nutritious but unreliable for iron supplementation
2019 · External reference
Medicinal value and application research of Moringa oleifera
2015 · External reference
Research progress on nutrition, function and application of Moringa oleifera leaves
10.13386/j.issn1002-0306.2020100030 · 2021 · External reference
Present and future of folate biofortification of crop plants
10.1093/jxb/ert483 · 2014 · External reference
Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model
10.1007/s13197-015-1828-x · 2016 · External reference
Analysis and evaluation of nutritional components in different locations of Moringa oleifera
10.13386/j.issn1002-0306.2016.22.061 · 2016 · External reference
Nutritional value of drumstick tree leaves
10.16005/j.cnki.tast.2004.01.002 · 2004 · External reference
Continuous flow synthesis of 5-methyltetrahydrofolate from folic acid
10.1021/acs.oprd.3c00323 · 2024 · External reference
Systems metabolic engineering of Bacillus subtilis for efficient biosynthesis of 5-methyltetrahydrofolate
10.1002/bit.27332 · 2020 · External reference
5-Methyltetrahydrofolate is a crucial factor in determining the bioaccessibility of folate in bread
10.1021/acs.jafc.2c03861 · 2022 · External reference
Role of the cGAS-STING pathway in systemic and organ-specific diseases
10.1038/s41581-022-00589-6 · 2022 · External reference
Research advances in the application of folate in animal production
2013 · External reference
Research progress on folate forms, stability and naturalization folate
10.12161/j.issn.1674-6729.2024.02.008 · 2024 · External reference
Polymorphism of MTHFR 1298A>C in relation to adverse pregnancy outcomes in Chinese populations
10.1002/mgg3.642 · 2019 · External reference
Exploratory metabolomics underscores the folate enzyme ALDH1L1 as a regulator of glycine and methylation reactions
10.3390/molecules27238394 · 2022 · External reference
Impact of folic acid and active folate supplementation on red blood cell folate levels in patients with unexplained recurrent pregnancy loss and MTHFR 677TT genotype
10.3969/j.issn.1674-8115.2024.06.009 · 2024 · External reference
[6S]-5-Methyltetrahydrofolate increases plasma folate more effectively than folic acid in women with the homozygous or wild-type 677C-->T polymorphism of methylenetetrahydrofolate reductase
10.1111/j.1476-5381.2009.00492.x · 2009 · External reference
Folate, folic acid and 5-methyltetrahydrofolate are not the same thing
10.3109/00498254.2013.845705 · 2014 · External reference
Folate and its impact on cancer risk
10.1007/s13668-018-0237-y · 2018 · External reference
Red cell or serum folate: what to do in clinical practice?
10.1515/cclm-2012-0639 · 2013 · External reference
Biological, dietetic and pharmacological properties of vitamin B9
10.1038/s41538-025-00396-w · 2025 · External reference
Folate bioavailability: implications for establishing dietary recommendations and optimizing status
10.3945/ajcn.2010.28674e · 2010 · External reference
Determination of folate vitamers in food and in Italian reference diet by high-performance liquid chromatography
10.1016/s0021-9673(99)00674-3 · 1999 · External reference
A validated liquid chromatographic method for determining folates in vegetables, milk powder, liver, and flour
10.1093/jaoac/82.1.119 · 1999 · External reference
Folate content and retention in commonly consumed vegetables in the South Pacific
10.1016/j.foodchem.2015.02.096 · 2015 · External reference
Research advances in the functions of plant folates
10.3724/sp.j.1259.2012.00525 · 2012 · External reference
Observation on the effect of folic acid supplementation during pregnancy on preventing neural tube defects in fetus
2024 · External reference
Effect of folic acid on the apoptotic pathway of neural tube defect cell model based on RNA sequencing technology
10.12467/j.issn.2096-3882.20240427 · 2024 · External reference
Effects of folate deficiency and related gene SNPs on neural tube defects
10.13488/j.smhx.20210237 · 2022 · External reference
Importance of abnormal methylation caused by folic acid deficiency in neural tube defects
10.13488/j.smhx.20200124 · 2020 · External reference
Declining rate of neural tube defectsand outcomesof defective infants in Shaanxi Province from 2003 to 2022
10.1007/s11017-025-09716-3 · 2024 · External reference
Research progress on the relationship between vitamin and oral clefts
10.7518/gjkq.2023094 · 2023 · External reference
Researchprogress on the role of environmentally induced DNA methylation in congenital cleft lipand/or palate
10.12016/j.issn.2096-1456.2023.08.009 · 2023 · External reference
Association of MTHFR and MTRR gene polymorphisms and folic acid supplementation with fetal congenital heart disease and cleft lip/palate
10.3969/j.issn.2095-8803.2020.07.015 · 2020 · External reference
Association of MTHFR and MTRR gene polymorphisms and folic acid supplementation with nonsyndromic cleft lip/palate in Gansu Province
10.13885/j.issn.1000-2812.2020.05.012 · 2020 · External reference
Association between maternal nutritional status during pregnancy and nonsyndromic cleft lip/palate
2020 · External reference
Research advances on ferroptosis and neuroinflammation in Alzheimer’s disease
10.3969/j.issn.1000-0399.2024.10.020 · 2024 · External reference
Research progress on pharmacological effects of Cynomorium songaricum in prevention and treatment of Alzheimer’s disease
External reference
Correlations between levels of homocysteine, folic acid and vitamin B12 and cognitive function in patients with Alzheimer’s disease
10.13479/j.cnki.issn.1674-8972.2020.05.08 · 2020 · External reference
Effect of folic acid on the expression of Flotillin-1 and β-amyloid protein in the brain of mice with Alzheimer’s disease inflammation
10.3969/j.issn.1671-7856.2024.08.002 · 2024 · External reference
Folic acid improves vascular cognitive impairment: a meta-analysis
10.3969/j.issn.1005-9202.2025.02.014 · 2025 · External reference
Research progress on mechanism of anti-colon cancer effect of B vitamins
10.14109/j.cnki.xyylc.2021.11.01 · 2021 · External reference
Folic acid intake and folate status and risk of cervical cancer: a systematic review and meta-analysis from 20 independent case-control studies and 4 RCTs
10.1093/cdn/nzaa044_029 · 2020 · External reference
Association of MTHFR 677C>T polymorphism with breast cancer risk: a case-control study and meta-analysis
10.4103/jcrt.jcrt_1063_20 · 2022 · External reference
Expression of methylenetetrahydrofolate dehydrogenase 1 in pancreatic cancer and its clinical significance
10.7659/j.issn.1005-6947.2024.09.016 · 2024 · External reference
Low erythrocyte folate levels and increased risk of invasive cervical cancer in Chinese women
10.1111/jog.15411 · 2022 · External reference
Correlation analysis between folate nutritional status and the occurrence/pathological characteristics of cervical cancer
10.19870/j.cnki.11-3716/ts.20230608.004 · 2023 · External reference
Folate deficiency is associated with Cervical Intraepithelial Neoplasia: perspective for prevention
10.1093/eurpub/ckv176.182 · 2015 · External reference
Effect of regional lymph nodes on tumor growth and dormancy of colonic cancer
2025 · External reference
Colon and rectal cancer: an emergent public health problem
10.3748/wjg.v30.i7.644 · 2024 · External reference
Folic acid inhibits colorectal cancer cell migration
10.1016/j.jnutbio.2018.06.007 · 2018 · External reference
Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRα/c-SRC/ERK1/2/NFκB/TP53 pathway: in vitro and in vivo studies
10.1038/srep11187 · 2015 · External reference
Targeted delivery of 5-fluorouracil to HT-29 cells using high efficient folic acid-conjugated nanoparticles
10.3109/10717544.2013.875603 · 2015 · External reference
Nanofabrication of PLGA-PEG-chitosan-folic acid systems for delivery of colchicine to HT-29 cancer cells
10.1080/09205063.2022.2105103 · 2023 · External reference
Safety of monosodium salt of L-5-methyltetrahydrofolic acid as a novel food pursuant to Regulation (EU) 2015/2283 and the bioavailability of folate from this source in the context of Directive 2002/46/EC, Regulation (EU) No 609/2013 and Regulation (EC) No 1925/2006
10.2903/j.efsa.2023.8417 · 2023 · External reference
Determination of calcium 6S-5-methyltetrahydrofolate in food fortification by reversed-phase high performance liquid chromatography
2024 · External reference
Perspectives in food and medicine homology
10.26599/fmh.2024.9420018 · 2024 · External reference
Analysis of food nutrition strengthening and supplement
10.16736/j.cnki.cn41-1434/ts.2020.02.039 · 2020 · External reference
Research progress in folate fortified food
10.12161/j.issn.1005-6521.2023.22.028 · 2023 · External reference
Preparation of folic acid-fortified rice bran nutritional powder for regulating human sub-health status, in: Nutrition Research and Clinical Practice—Abstracts of the 14th National Nutrition Science Conference, 11th Asia-Pacific Clinical Nutrition Conference and 2nd Global Chinese Nutrition Scientists Conference, Hohhot
2019 · External reference
Effect of folic acid on serum HCY level in chronic disease patients with hyperhomocysteinemia in community
2023 · External reference
An international regulatory review of food health-related claims in functional food products labeling
10.1016/j.jff.2020.103896 · 2020 · External reference
Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age
10.1093/ajcn/84.1.156 · 2006 · External reference
Hypothetical regulation of folate biosynthesis and strategies for folate overproduction in lactic acid bacteria
10.3746/pnf.2023.28.4.386 · 2023 · External reference
Research advances in folate biosynthesis and biofortification in crops
10.3969/j.issn.0517-6611.2024.06.003 · 2024 · External reference
Research progress in folate metabolism and bioenhancement of plants
10.13271/j.mpb.021.003778 · 2023 · External reference
Improving the production of 4-aminobenzoic in engineered Escherichia coli by combinatorial regulation
10.13345/j.cjb.190107 · 2019 · External reference
Plasmodium para-aminobenzoate synthesis and salvage resolve avoidance of folate competition and adaptation to host diet
10.1016/j.celrep.2018.12.062 · 2019 · External reference
Biosynthesis regulation of folates and phenols in plants
10.1016/j.scienta.2021.110561 · 2022 · External reference
Folate biofortification in food crops
10.1016/j.copbio.2016.12.003 · 2016 · External reference
A central role for gamma-glutamyl hydrolases in plant folate homeostasis
10.1111/j.1365-313x.2010.04330.x · 2010 · External reference
Over-expression of SiADCL1 in Arabidopsis modulates folate and amino acid metabolism to impact on flowering time
10.1016/j.plaphy.2024.109253 · 2024 · External reference
Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode
10.1074/jbc.ra119.012256 · 2020 · External reference
Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement
10.1016/j.bbagen.2014.03.012 · 2014 · External reference
Arabidopsis 10-formyl tetrahydrofolate deformylases are essential for photorespiration
10.1105/tpc.108.058701 · 2008 · External reference
10.3390/biophysica3040044
10.3390/biophysica3040044 · External reference
Marker-assisted pyramiding of γ-tocopherol methyltransferase and glutamate formiminotransferase genes for development of biofortified sweet corn hybrids
10.7717/peerj.13629 · 2022 · External reference
Optimization of folate-producing medium components and fermentation conditions for Lactococcus lactis KLDS4.0325 using response surface methodology
10.3724/sp.j.1123.2020.00118 · 2020 · External reference
Construction and optimization of the trehalose multienzyme catalysis system in Escherichia coli
10.13995/j.cnki.11-1802/ts.041677 · 2025 · External reference
Nucleic acid delivery effects of nanoplastics based on plant gene silencing technology (RNAi)
10.27662/d.cnki.gznlc.2024.000450 · 2024 · External reference
Modulation of intestinal flora by plant polyphenols based on in vitro fermentation models
10.13386/j.issn1002-0306.2024110256 · 2025 · External reference
Directed evolution of a 6-phosphogluconate dehydrogenase for operating an enzymatic fuel cell at lowered anodic pHs
10.1016/j.jelechem.2019.113444 · 2019 · External reference
Engineering cellular metabolism
10.1016/j.cell.2016.02.004 · 2016 · External reference
High-level semi-synthetic production of the potent antimalarial artemisinin
10.1038/nature12051 · 2013 · External reference
Effects of lactic acid bacteria fermentation on the sensory, physicochemical, and flavor quality of sour bamboo shoots
10.19812/j.cnki.jfsq11-5956/ts.20241030005 · 2025 · External reference
Application and prospect of microbial fermentation technology in food industry
10.16043/j.cnki.cfs.2025.13.007 · 2025 · External reference
Smart fermentation technologies: microbial process control in traditional fermented foods
10.3390/fermentation11060323 · 2025 · External reference
Application of biocatalytic technology in chemical pharmaceutical industry
2019 · External reference
Application of biocatalytic technology in chemical pharmaceuticals
10.20087/j.cnki.1672-8114.2024.06.038 · 2024 · External reference
Research progress in enzymatic preparation of alkyl glycosides
2021 · External reference
Metabolic regulation of lysosomes and their role in meat tenderization: a review
10.7506/spkx1002-6630-20240718-191 · 2025 · External reference
Application of natural polysaccharide-based nanodelivery carriers in functional foods
10.16429/j.1009-7848.2025.01.041 · 2025 · External reference
Drug delivery systems: a new frontier in nano-technology
2017 · External reference
Application of mRNA nano-delivery system in CAR-T tumor immunotherapy
10.13345/j.cjb.230541 · 2024 · External reference
Application of nanovesicle delivery systems in cardiovascular diseases
2023 · External reference
Nanotechnology-based drug delivery systems for curcumin and its derivatives in the treatment of cardiovascular diseases
10.1016/j.jff.2024.106476 · 2024 · External reference
Gut microecological prescription: a novel approach to regulating intestinal micro-ecological balance
10.2147/ijgm.s504616 · 2025 · External reference
Plant-based biofortification of selenium and zinc: new exploration of dietary supplements
10.3969/j.issn.1002-6630.2022.47.019 · 2022 · External reference
Biofortification: a long-term solution to improve global health-a review
10.1016/j.chemosphere.2022.137713 · 2023 · External reference
Design, construction and intensification of enzymatic bioelectrocatalytic systems
10.12211/2096-8280.2022-018 · 2022 · External reference
10.1016/b978-0-12-823034-3.00006-6
10.1016/b978-0-12-823034-3.00006-6 · External reference
Extraterrestrial artificial photosynthetic materials for in-situ resource utilization
10.1093/nsr/nwab104 · 2021 · External reference
Analysis of differentially expressed genes in response to jasmonate during orobanche parasitism on sunflower
External reference
Differential gene expression analysis pipelines and bioinformatic tools for the identification of specific biomarkers: a review
10.1016/j.csbj.2024.02.018 · 2024 · External reference
Multi-transcriptome integration analysis and co-expression network construction of barley under drought stress
2024 · External reference
Application of weighted gene co-expression network analysis in biomedicine
10.13345/j.cjb.170006 · 2017 · External reference
Cloning, bioinformatics analysis and expression pattern of CdMYC2 gene in Camellia vietnamensis
10.15886/j.cnki.rdswxb.20250031 · 2025 · External reference
Agrobacterium-mediated transformation method for in vitro germinated pollen in maize
10.13597/j.cnki.maize.science.20240405 · 2024 · External reference
Research progress on CRISPR system for gene editing in Bacillus subtilis
10.13343/j.cnki.wsxb.20240688 · 2025 · External reference
New drugs for functional cure of hepatitis B: focus on antisense oligonucleotides and small interfering RNA
10.12449/jch250102 · 2025 · External reference
Research progress on stress resistance and flowering-related miRNAs and their application in luffa
2018 · External reference
Applications and development trends of microarray technology
2008 · External reference
Investigation of functional characteristics of methyltransferase genes based on metabolomics
10.16429/j.1009-7848.2025.03.010 · External reference
Heterologous expression and enzymatic properties of fucoidanase Fcn1 from Marine flavobacterium
10.12301/spxb202300442 · 2024 · External reference
Research progress on artemisinin synthesis based on plant genetic engineering
10.19540/j.cnki.cjcmm.2019.0089 · 2019 · External reference
MPOD: applications of integrated multi-omics database for medicinal plants
10.1111/pbi.13769 · 2021 · External reference
Improving Escherichia coli prokaryotic expression system with low virulence and high efficiency by recombination technology
10.13344/j.microbiol.china.200116 · 2021 · External reference
Developing a dynamic equilibrium system in Escherichia coli to improve the production of recombinant proteins
10.1007/s00253-022-12145-0 · 2022 · External reference
Optimization of expression conditions of scFv-AFP and its immunologic activity
10.11665/j.issn.1000-5048.2012.05.015 · 2012 · External reference
Prokaryotic expression analysis of α-ketoglutaric acid decarboxylase from Synechocystis sp. PCC6803
10.13836/j.jjau.2020069 · 2020 · External reference
Metabolic engineering of Bacillus subtilis fueled by systems biology: recent advances and future directions
10.1016/j.biotechadv.2016.11.003 · 2016 · External reference
Research advances in CRISPR-Cas systems for genome editing in Bacillus subtilis
10.13304/j.nykjdb.2023.0260 · 2025 · External reference
Research advances in yeast as an expression system for foreign genes
2001 · External reference
Research progress in mechanism models and artificial intelligence models for protein expression systems
10.13345/j.cjb.240935 · 2025 · External reference
Metabolic engineering of Saccharomyces cerevisiae for de novo synthesis of rosin
2025 · External reference
Yeast Systems biology: model organism and cell factory
10.1002/biot.201800421 · 2019 · External reference
Review on high-level Aspergillus niger glucose oxidase production engineering strains
2013 · External reference
Functional analysis of protein post-translational modifications using genetic codon expansion
10.1002/pro.4618 · 2023 · External reference
Research strategies of natural products biosynthesis pathways and key enzymes in medicinal plants
10.13560/j.cnki.biotech.bull.1985.2021-0949 · 2021 · External reference
Separation of recombinant β-glucuronidase from transgenic tobacco by aqueous two-phase extraction
10.1016/j.bej.2010.01.009 · 2010 · External reference
Current status and prospects of plant genome editing reagent delivery and transformation systems
10.1360/n052017-00239 · 2017 · External reference
Research progress and application of insect cell-baculovirus expression vector system
10.13309/j.cnki.pmi.2014.02.016 · 2014 · External reference
Genomics and synthetic biology of traditional Chinese medicine
2012 · External reference
Genome sequence of the model medicinal mushroom Ganoderma lucidum
10.1038/ncomms1923 · 2012 · External reference
A functional genomics approach to tanshinone biosynthesis provides stereochemical insights
10.1021/ol902051v · 2009 · External reference
Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production
10.1021/ja2114486 · 2012 · External reference
Production of L-5-methyltetrahydrofolate by genetically engineered Escherichia coli
2023 · External reference
Strategies of phage contamination prevention in industry
10.17352/ojb.000014 · 2020 · External reference
The application and control of bacteriophage in food industry
10.13344/j.microbiol.china.210486 · 2021 · External reference
10.5772/intechopen.81151
10.5772/intechopen.81151 · External reference
The evolution of folate supplementation–from one size for all to personalized, precision, poly-paths
10.2478/jtim-2023-0087 · 2023 · External reference
Regulatory mechanisms of one-carbon metabolism enzymes
10.1016/j.jbc.2023.105457 · 2023 · External reference
Reversal of cytosolic one-carbon flux compensates for loss of the mitochondrial folate pathway
10.1016/j.cmet.2016.04.016 · 2016 · External reference