Research graph
References from Rosmarinic acid, the key dietary antioxidant in <i>Rosmarinus officinalis</i> L. identified by integrated screening, targets PPARγ to activate Nrf2/NQO1 axis and mitigate oxidative stress. Local targets link to admitted publications; unresolved targets remain external evidence.
Obesity, bioactive lipids, and adipose tissue inflammation in insulin resistance
10.3390/nu12051305 · 2020 · External reference
Nutritional value and antioxidant activity of Artemisia princeps, an edible plant frequently used in folk food in the Xiangxi region
10.26599/fmh.2025.9420043 · 2025 · External reference
Antioxidant and hepatoprotective effects of Hypsizygus ulmarius polysaccharide on alcoholic liver injury in rats
10.1016/j.fshw.2021.04.015 · 2021 · External reference
Que Zui tea ameliorates hepatic lipid accumulation and oxidative stress in high fat diet induced nonalcoholic fatty liver disease
10.1016/j.foodres.2022.111196 · 2022 · External reference
Activation of the PPARγ prevents ferroptosis-induced neuronal loss in response to intracerebral hemorrhage through synergistic actions with the Nrf2
10.3389/fphar.2022.869300 · 2022 · External reference
Ginkgolide B attenuates hyperlipidemia by restoring sphingolipid homeostasis and activating PPARα and Nrf2 pathways
10.1038/s41598-025-14626-4 · 2025 · External reference
Genistein-7-O-octanoate: a promising natural antioxidant for stabilizing soybean oil during storage and high-temperature frying
10.1016/j.foodres.2025.118257 · 2026 · External reference
Transformation from traditional medicine-food homology to modern food-medicine homology
10.26599/fmh.2024.9420014 · 2024 · External reference
Global policy changes on homologous substances of food and medicine
10.26599/fmh.2026.9420126 · 2026 · External reference
Rosmarinus eriocalyx: an alternative to Rosmarinus officinalis as a source of antioxidant compounds
10.1016/j.foodchem.2016.09.063 · 2017 · External reference
Assessing the efficacy of rosemary extract as a natural preservative for enhancing oxidative stability and preventing rancidity in linseed oil
10.1007/s11694-025-03107-x · 2025 · External reference
Hepatoprotective effects of rosmarinic acid on ovalbumin-induced intestinal food allergy mouse model
10.3390/molecules28020788 · 2023 · External reference
Anti-inflammatory effects of ethanolic extract of Rosmarinus officinalis L. and rosmarinic acid in a rat model of neuropathic pain
10.1016/j.biopha.2016.12.049 · 2017 · External reference
Rosemary (Rosmarinus officinalis L.): extraction techniques, analytical methods and health-promoting biological effects
10.1007/s11101-021-09745-5 · 2021 · External reference
Anticancer effects of rosemary (Rosmarinus officinalis L.) extract and rosemary extract polyphenols
10.3390/nu8110731 · 2016 · External reference
A network-based analysis of the types of coronary artery disease from traditional Chinese medicine perspective: potential for therapeutics and drug discovery
10.1016/j.jep.2013.11.007 · 2014 · External reference
Rosmanol induces breast cancer cells apoptosis by regulating PI3K/AKT and STAT3/JAK2 signaling pathways
10.3892/ol.2021.12892 · 2021 · External reference
AutoDock Vina 1.2.0: new docking methods, expanded force field, and python bindings
10.1021/acs.jcim.1c00203 · 2021 · External reference
AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
10.1002/jcc.21334 · 2010 · External reference
Hesperetin’s antigenotoxicity: the impact on EMS-made lesions within Drosophila melanogaster somatic cells’ DNA, disclosed through molecular modeling
10.1016/j.phymed.2025.157728 · 2026 · External reference
Anti-inflammatory and antioxidant effects of chaetoglobosin Vb in LPS-induced RAW264.7 cells: achieved via the MAPK and NF-κB signaling pathways
10.1016/j.fct.2020.111915 · 2021 · External reference
Flammulina velutipes polysaccharide exerts immunomodulatory function involving RSAD2 to regulate the NF-κB/MAPK signaling pathway in RAW264.7 macrophage cells and in mouse spleen cells
10.1016/j.ijbiomac.2025.142985 · 2025 · External reference
Unveiling the potential of Nelumbo nucifera-derived liensinine to target the myostatin protein and to counteract muscle atrophy
10.1021/acs.jafc.3c09002 · 2024 · External reference
Naphthoquinone derivatives from the endophytic fungus Fusarium solani induce pancreatic cancer cells apoptosis via targeting EGFR-mediated PI3K/Akt pathway
10.1021/acs.jafc.4c08652 · 2024 · External reference
A rapid analysis method to discover antioxidant active components and mechanisms in soybean: untargeted metabolomics combined with network pharmacology and spectrum-effect relationship-component knockout-identification techniques
10.26599/fshw.2025.9250620 · 2025 · External reference
Glucomannogalactan inhibits senescence by promoting nuclear translocation of NRF2
10.1016/j.ijbiomac.2025.141059 · 2025 · External reference
FER1L6 ameliorates insulin resistance by regulating GLUT4 expression
10.26599/fmh.2025.9420070 · 2025 · External reference
Characteristic components from Rehmannia radix and their effects on insulin resistance through PI-3K/AKT signaling pathway in HepG2 cells
10.26599/fmh.2025.9420073 · 2025 · External reference
Potential of cyclodipeptides in combating oxidative stress in chronic diseases
10.1016/j.phrs.2025.108076 · 2025 · External reference
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
10.1038/nature10449 · 2011 · External reference
Antioxidant activity measurement of oleoresin from rosemary and sage
10.1016/j.indcrop.2014.07.043 · 2014 · External reference
Critical review on biological effect and mechanisms of diterpenoids in Rosmarinus officinalis
10.26599/fmh.2025.9420021 · 2025 · External reference
Viability of near infrared spectroscopy for a rapid analysis of the bioactive compounds in intact cocoa bean husk
10.1016/j.foodcont.2020.107526 · 2021 · External reference
Network pharmacology-based approach to investigate the molecular targets and molecular mechanisms of Rosmarinus officinalis L. for treating aging-related disorders
10.1007/s10522-024-10122-w · 2024 · External reference
Increased intestinal permeability in older subjects impacts the beneficial effects of dietary polyphenols by modulating their bioavailability
10.1021/acs.jafc.0c04976 · 2020 · External reference
Rosmarinic acid ameliorates acetaminophen-induced acute liver injury in mice via RACK1/TNF-α mediated antioxidant effect
10.1080/13880209.2021.1974059 · 2021 · External reference
Rosmarinic acid attenuates β-amyloid-induced oxidative stress via Akt/GSK-3β/Fyn-mediated Nrf2 activation in PC12 cells
10.1016/j.freeradbiomed.2018.03.028 · 2018 · External reference
Reno-protective effect of mangiferin against methotrexate-induced kidney damage in male rats: PPARγ-mediated antioxidant activity
10.1016/j.jsps.2022.06.026 · 2022 · External reference
RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network
10.1038/s41467-017-00215-1 · 2017 · External reference
Oxidative stress and apoptosis after acute respiratory hypoxia and reoxygenation in rat brain
10.1016/j.redox.2017.02.014 · 2017 · External reference
Naringin: a flavanone with a multifaceted target against sepsis-associated organ injuries
10.1016/j.phymed.2024.155707 · 2024 · External reference
PM2.5 promotes platelet activation and thrombosis via ROS/MAPKs pathway-mediated mitochondrial dysfunction
10.1016/j.envres.2025.122116 · 2025 · External reference
Nontargeted metabolomics combining with intestinal microbiota and hypolipidemia targets elucidates anti-hyperlipidemia effect of Sangju yinzha tea in hyperlipidemia rats
10.1016/j.fbio.2025.106012 · 2025 · External reference
