Research graph
References from Subcutaneously injected Chinese herbal hydrogel as a NETs-scavenging niche for restoring immune homeostasis in lupus. Local targets link to admitted publications; unresolved targets remain external evidence.
Systemic lupus erythematosus: A review
10.1001/jama.2024.2315 · 2024 · External reference
The mosaic of systemic lupus erythematosus: From autoimmunity to autoinflammation and immunodeficiency and back
10.1016/j.autrev.2024.103675 · 2024 · External reference
Pathogenesis of systemic lupus erythematosus: Risks, mechanisms and therapeutic targets
10.1136/ard-2022-223741 · 2023 · External reference
Immunometabolism in systemic lupus erythematosus
10.1038/s41584-025-01267-0 · 2025 · External reference
Immunopathogenesis of systemic lupus erythematosus: An update
10.1016/j.autrev.2024.103648 · 2024 · External reference
The diverse roles of neutrophils from protection to pathogenesis
10.1038/s41590-024-02006-5 · 2024 · External reference
Neutrophil diversity and function in health and disease
10.1038/s41392-024-02049-y · 2024 · External reference
Neutrophil extracellular traps in homeostasis and disease
10.1038/s41392-024-01933-x · 2024 · External reference
Neutrophils and NETs in kidney disease
10.1038/s41581-025-00944-3 · 2025 · External reference
TREM2 drives neutrophil extracellular traps-induced dendritic cell maturation and contributes to lupus progression
10.1002/advs.202508938 · 2026 · External reference
Systemic lupus erythematosus: Pathogenesis and targeted therapy
10.1186/s43556-024-00217-8 · 2024 · External reference
Systemic lupus erythematosus: New diagnostic and therapeutic approaches
10.1146/annurev-med-043021-032611 · 2023 · External reference
Therapeutic potential of lipid nanoparticle-encapsulated CD19-targeting mRNAs in lupus and rheumatoid arthritis
10.1002/advs.202501628 · 2025 · External reference
Nanomedicine targeting the PD-1/PD-L1 axis in autoimmune diseases: Breaking conventional barriers to restore immune tolerance
10.1186/s12951-025-03766-4 · 2025 · External reference
Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis
10.1038/s41590-022-01388-8 · 2023 · External reference
Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
10.1016/j.cmet.2022.06.008 · 2022 · External reference
Lung immune cell niches and the discovery of new cell subtypes
10.1002/advs.202405490 · 2024 · External reference
Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression
10.1016/j.immuni.2023.06.017 · 2023 · External reference
Immune microniches shape intestinal Treg function
10.1038/s41586-024-07251-0 · 2024 · External reference
Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity
10.1016/j.ccell.2024.06.014 · 2024 · External reference
Plant-derived Chinese herbal hydrogel microneedle patches for wound healing
10.1002/smll.202404850 · 2024 · External reference
Modulation of macrophages by a paeoniflorin-loaded hyaluronic acid-based hydrogel promotes diabetic wound healing
10.1016/j.mtbio.2021.100139 · 2021 · External reference
Microfluidic-engineered Chinese herbal nanocomposite hydrogel microspheres for diabetic wound tissue regeneration
10.1186/s12951-024-02998-0 · 2024 · External reference
Microalgae-derived extracellular vesicles synergize with herbal hydrogel for energy homeostasis in osteoarthritis treatment
10.1021/acsnano.4c16085 · 2025 · External reference
Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease
10.1016/j.kint.2016.07.040 · 2017 · External reference
DNase I-mediated chemotactic nanoparticles for NETs targeting and microenvironment remodeling treatment of acute ischemic stroke
10.1002/advs.202503689 · 2025 · External reference
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment
10.1016/j.ccell.2024.01.013 · 2024 · External reference
RNA externalized by neutrophil extracellular traps promotes inflammatory pathways in endothelial cells
10.1002/art.41796 · 2021 · External reference
Reactive oxygen species -induced modifications of fibrin clots as a link between immune responses and atherothrombosis in systemic lupus erythematosus
10.1002/art.43371 · 2026 · External reference
Hyaluronic acid methacrylate/laponite hydrogel loaded with BMP4 and maintaining its bioactivity for scar-free wound healing
10.2307/jj.2354076.12 · 2023 · External reference
MicroRNA-125a-loaded polymeric nanoparticles alleviate systemic lupus erythematosus by restoring effector/regulatory T cells balance
10.1021/acsnano.9b09998 · 2020 · External reference
Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses
10.1016/j.cmet.2023.03.010 · 2023 · External reference
Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus
10.1126/sciimmunol.abq0178 · 2023 · External reference
Macrophage transcription factor TonEBP promotes systemic lupus erythematosus and kidney injury via damage-induced signaling pathways
10.1016/j.kint.2023.03.030 · 2023 · External reference
Laquinimod delays and suppresses nephritis in lupus-prone mice and affects both myeloid and lymphoid immune cells
10.1002/art.38259 · 2014 · External reference
Research advances on targeted-treg therapies on immune-mediated kidney diseases
10.1016/j.autrev.2022.103257 · 2023 · External reference
Lupus nephritis
10.1038/s41572-025-00653-y · 2025 · External reference
Update on pharmacological activities, security, and pharmacokinetics of rhein
10.1155/2021/4582412 · 2021 · External reference
DNase I functional microgels for neutrophil extracellular trap disruption
10.1039/d1bm01591e · 2022 · External reference
Rhein alleviates cisplatin-induced acute kidney injury via downregulation of NOX4-COX2/PGFS signaling pathway
10.2147/dddt.s515409 · 2025 · External reference
Retinal microenvironment-protected rhein-GFFYE nanofibers attenuate retinal ischemia-reperfusion injury via inhibiting oxidative stress and regulating microglial/macrophage M1/M2 polarization
10.1002/advs.202302909 · 2023 · External reference
