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References from From mRNA stabilisation to mirror life: Biological orthogonality, incremental risk, and anticipatory governance. Local targets link to admitted publications; unresolved targets remain external evidence.
Confronting risks of mirror life
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An experiment assessing effects of personalized feedback about genetic susceptibility to obesity on attitudes towards diet and exercise
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Patient and public perspectives on cell and gene therapies: a systematic review
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COVID-19 vaccine boosters for young adults: a risk benefit assessment and ethical analysis of mandate policies at universities
10.1136/jme-2022-108449 · 2024 · External reference
Inotersen treatment for patients with hereditary transthyretin amyloidosis
10.1056/nejmoa1716793 · 2018 · External reference
mRNA-based cancer vaccines: a therapeutic strategy for the treatment of melanoma patients
10.3390/vaccines9101060 · 2021 · External reference
In vivo biodistribution and pharmacokinetics of 18F-labelled spiegelmers: a new class of oligonucleotidic radiopharmaceuticals
10.1007/s00259-004-1669-8 · 2005 · External reference
Unresolved reference
2025 · External reference
mRNA structure determines modification by pseudouridine synthase 1
10.1038/s41589-019-0353-z · 2019 · External reference
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Unresolved reference
2023 · External reference
The bial 10‐2474 phase 1 study—a drug development perspective and recommendations for future first‐in‐human trials
10.1002/jcph.889 · 2017 · External reference
Redesigning the genetic polymers of life
10.1021/acs.accounts.0c00886 · 2021 · External reference
What is XNA?
10.1002/anie.201905999 · 2019 · External reference
Mutant polymerases capable of 2′ fluoro-modified nucleic acid synthesis and amplification with improved accuracy
10.1039/d2cb00064d · 2022 · External reference
Unresolved reference
2014 · External reference
RNA-targeted therapeutics
10.1016/j.cmet.2018.03.004 · 2018 · External reference
Genetic essentialism: on the deceptive determinism of DNA
10.1037/a0021860 · 2011 · External reference
Genetic essentialism: the mediating role of essentialist biases on the relationship between genetic knowledge and the interpretations of genetic information
10.1016/j.ejmg.2020.104119 · 2021 · External reference
Genetics and the destiny of man
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Assembling unregulated DNA segments bypasses synthesis screening: regulate fragments as select agents
10.1038/s41467-025-67955-3 · 2026 · External reference
Chemistry, structure and function of approved oligonucleotide therapeutics
10.1093/nar/gkad067 · 2023 · External reference
Foundations for engineering biology
10.1038/nature04342 · 2005 · External reference
Unresolved reference
2025 · External reference
Nusinersen versus sham control in infantile-onset spinal muscular atrophy
10.1056/nejmoa1702752 · 2017 · External reference
Benefit-risk assessment of COVID-19 vaccine, mRNA (Comirnaty) for age 16–29 years
10.1016/j.vaccine.2022.03.030 · 2022 · External reference
UV irradiation and autoclave treatment for elimination of contaminating DNA from laboratory consumables
10.1016/j.fsigen.2009.06.008 · 2010 · External reference
Xenobiology for the biocontainment of synthetic organisms: opportunities and challenges
10.3390/life14080996 · 2024 · External reference
Implicit essentialism: genetic concepts are implicitly associated with fate concepts
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Verdict confirms fate of 'elephant man' drug volunteers
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Synthetic DNA synthesis and assembly: putting the synthetic in synthetic biology
10.1101/cshperspect.a023812 · 2017 · External reference
COVID-19 vaccine rumors and conspiracy theories: the need for cognitive inoculation against misinformation to improve vaccine adherence
10.1371/journal.pone.0251605 · 2021 · External reference
Mirror life: addressing a potential biothreat
2025 · External reference
Genetic determinism in the genetics curriculum: an exploratory study of the effects of Mendelian and Weldonian emphases
10.1007/s11191-017-9900-8 · 2017 · External reference
Clinical pharmacokinetics of approved RNA therapeutics
10.3390/ijms24010746 · 2023 · External reference
Suppression of RNA recognition by toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA
10.1016/j.immuni.2005.06.008 · 2005 · External reference
Beyond patchwork precaution in the dual-use governance of synthetic biology
10.1007/s11948-012-9365-8 · 2013 · External reference
The logic of virus evolution
10.1016/j.chom.2022.06.008 · 2022 · External reference
Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients
10.1038/s41541-023-00742-7 · 2023 · External reference
The undue influence of genetic information on senior medical students' treatment decisions
10.1186/s12909-023-04895-w · 2023 · External reference
Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics
10.1038/s12276-023-01086-x · 2023 · External reference
Functionally enhanced XNA aptamers discovered by parallelized library screening
10.1021/jacs.3c09497 · 2023 · External reference
Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib–dexamethasone in relapsed/refractory multiple myeloma: a phase IIa study
10.1038/leu.2017.5 · 2017 · External reference
Risk assessment of RNAi based biopesticides. New Crops 1
10.1016/j.ncrops.2024.100019 · 2024 · External reference
Causal reasoning about human behavior genetics: synthesis and future directions
10.1007/s10519-018-9909-z · 2019 · External reference
A semi-synthetic organism with an expanded genetic alphabet
10.1038/nature13314 · 2014 · External reference
Directed evolution of a highly efficient TNA polymerase achieved by homologous recombination
10.1038/s41929-024-01233-1 · 2024 · External reference
The forensic use of behavioral genetics in criminal proceedings: case of the MAOA-L genotype
10.1016/j.ijlp.2016.09.005 · 2017 · External reference
CC motif-ligand 2 inhibition with emapticap pegol (NOX-E36) in type 2 diabetic patients with albuminuria
10.1093/ndt/gfv459 · 2017 · External reference
Tailor made: the art of therapeutic mRNA design
10.1038/s41573-023-00827-x · 2024 · External reference
Linking virus genomes with host taxonomy
10.3390/v8030066 · 2016 · External reference
Unresolved reference
External reference
Be a GEM: biocontained, environmentally applied, genetically engineered microbes
10.1016/j.addr.2025.115578 · 2025 · External reference
The critical contribution of pseudouridine to mRNA COVID-19 vaccines
10.3389/fcell.2021.789427 · 2021 · External reference
Modifications in an emergency: the role of N1-methylpseudouridine in COVID-19 vaccines
10.1021/acscentsci.1c00197 · 2021 · External reference
Unresolved reference
2018 · External reference
Molecular metaphors: the gene in popular discourse
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Unresolved reference
1995 · External reference
Making knowledge in synthetic biology: design meets kludge
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Exploration, iterativity and kludging in synthetic biology
10.1016/j.crci.2010.06.021 · 2011 · External reference
Synthetic genetic polymers capable of heredity and evolution
10.1126/science.1217622 · 2012 · External reference
mRNA-based therapeutics: powerful and versatile tools to combat diseases
10.1038/s41392-022-01007-w · 2022 · External reference
Classifying genetic essentialist biases using large language models
10.1007/s13164-025-00770-3 · 2025 · External reference
The 3′ untranslated region of picornavirus RNA: features required for efficient genome replication
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Safety of mRNA vaccines administered during the initial 6 months of the US COVID-19 vaccination programme: an observational study of reports to the vaccine adverse event reporting system and v-safe
10.1016/s1473-3099(22)00054-8 · 2022 · External reference
Cascade versus mechanism: the diversity of causal structure in science
10.1086/723623 · 2026 · External reference
Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics
10.1016/j.cbpa.2019.06.006 · 2019 · External reference
Harm, ethics committees and the gene therapy death
10.1136/jme.27.3.148 · 2001 · External reference
Xenobiology: a new form of life as the ultimate biosafety tool
10.1002/bies.200900147 · 2010 · External reference
COVID-19 mRNA vaccines: platforms and current developments
10.1016/j.ymthe.2022.02.016 · 2022 · External reference
Duchenne gene therapy halted after three deaths and company u turn
10.1136/bmj.r1548 · 2025 · External reference
Catalysts from synthetic genetic polymers
10.1038/nature13982 · 2015 · External reference
Turning mirror-image oligonucleotides into drugs: the evolution of spiegelmer® therapeutics
10.1016/j.drudis.2014.09.004 · 2015 · External reference
Efficacy and safety of an mRNA-based RSV PreF vaccine in older adults
10.1056/nejmoa2307079 · 2023 · External reference
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10.2307/j.ctv1pncnrh · 2007 · External reference
Unresolved reference
2026 · External reference
The advances of adjuvants in mRNA vaccines
10.1038/s41541-023-00760-5 · 2023 · External reference
Mirror-image T7 transcription of chirally inverted ribosomal and functional RNAs
10.1126/science.abm0646 · 2022 · External reference
Putative host-derived insertions in the genomes of circulating SARS-CoV-2 variants
10.1128/msystems.00179-22 · 2022 · External reference
Mirror‐image oligonucleotides: history and emerging applications
10.1002/chem.201900149 · 2019 · External reference
Ionizable lipid nanoparticles of mRNA vaccines elicit NF-κB and IRF responses through toll-like receptor 4
10.1038/s41541-025-01124-x · 2025 · External reference