References

Metabolic engineering of Bacillus subtilis toward taxadiene biosynthesis as the first committed step for taxol production

10.3389/fmicb.2019.00218 · 2019 · External reference

Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli

10.1126/science.1191652 · 2010 · External reference

Production of the terpenoid-based biofuel α-bisabolene by metabolically engineered Corynebacterium glutamicum

10.1007/s11274-025-04588-0 · 2025 · External reference

Feedback inhibition of Deoxy- D -xylulose-5-phosphate synthase regulates the methylerythritol 4-Phosphate pathway

10.1074/jbc.m113.464636 · 2013 · External reference

Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida

10.1016/j.ymben.2024.02.004 · 2024 · External reference

Industrial microorganisms

2016 · External reference

Biosynthesis of zeaxanthin in recombinant Pseudomonas putida

10.1007/s00253-010-2961-0 · 2011 · External reference

Exploring the potential of the model cyanobacterium synechocystis PCC 6803 for the photosynthetic production of various high-value terpenes

10.1186/s13068-022-02211-0 · 2022 · External reference

Engineering yeast for the production of plant terpenoids using synthetic biology approaches

10.1039/d3np00005b · 2023 · External reference

Prenol production in a microbial host via the “repass” pathways

10.1016/j.ymben.2025.01.009 · External reference

Automation and machine learning drive rapid optimization of isoprenol production in Pseudomonas putida

10.1038/s41467-025-66304-8 · External reference

Two-step pathway for isoprenoid synthesis

10.1073/pnas.1812935116 · 2019 · External reference

Exploring the potential of the model cyanobacteria synechococcus PCC 7002 and PCC 7942 for the photoproduction of high-value terpenes: a comparison with synechocystis PCC 6803

10.3390/biom13030504 · 2023 · External reference

Alternate routes to acetate tolerance lead to varied isoprenol production from mixed carbon sources in Pseudomonas putida

10.1128/aem.02123-24 · 2025 · External reference

Bacterial sources and sinks of isoprene, a reactive atmospheric hydrocarbon

10.1046/j.1462-2920.2000.00095.x · 2000 · External reference

Engineering phototrophic Cyanobacteria as a robust platform for production of plant-derived bioactive terpenoids

10.1016/j.cej.2025.172487 · 2026 · External reference

Directed evolution of an E. coli inner membrane transporter for improved efflux of biofuel molecules

10.1186/1754-6834-6-81 · 2013 · External reference

Evaluating isoprenol production using the IPP-Bypass pathway in the oleaginous yeast Rhodosporidium toruloides

10.1186/s13068-026-02750-w · 2026 · External reference

Construction of isopentenol utilization pathway and artificial multifunctional enzyme for miltiradiene synthesis in Saccharomyces cerevisiae

10.1016/j.biortech.2025.132065 · 2025 · External reference

Metabolic engineering of Bacillus subtilis for terpenoid production

10.1007/s00253-015-6950-1 · 2015 · External reference

Unresolved reference

2021 · External reference

Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum

10.1186/1471-2180-12-198 · 2012 · External reference

Production and glucosylation of C50 and C40 carotenoids by metabolically engineered Corynebacterium glutamicum

10.1007/s00253-013-5359-y · External reference

Optimization of the IPP precursor supply for the production of lycopene, decaprenoxanthin and astaxanthin by Corynebacterium glutamicum

10.3389/fbioe.2014.00028 · External reference

Production of the marine, carotenoid astaxanthin by metabolically engineered Corynebacterium glutamicum

10.3390/md14070124 · 2016 · External reference

Carotenoid production by recombinant corynebacterium glutamicum: strain construction, cultivation, extraction, and quantification of carotenoids and terpenes

External reference

Patchoulol production with metabolically engineered Corynebacterium glutamicum

10.3390/genes9040219 · External reference

Terpenes, hormones, and life: isoprene rule revisited

10.1530/joe-19-0084 · 2019 · External reference

Host organisms

2016 · External reference

Building Streptomyces albus as a chassis for synthesis of bacterial terpenoids

10.1039/d2sc06033g · 2023 · External reference

Metabolic engineering for the biosynthesis of pentalenene in the rapidly growing bacterium Vibrio natriegens

10.3390/fermentation11050249 · External reference

Expanding the terpene universe: synthetic biology and non-natural chemistry in engineered microorganisms

10.3390/molecules30204065 · External reference

Biotechnological production of limonene in microorganisms

10.1007/s00253-016-7337-7 · 2016 · External reference

Biosynthesis of pinene from glucose using metabolically-engineered Corynebacterium glutamicum

10.1007/s10529-014-1578-2 · 2014 · External reference

Isopentenyl diphosphate (IPP)-Bypass mevalonate pathways for isopentenol production

10.1016/j.ymben.2015.12.002 · 2016 · External reference

Development of a terpenoid-production platform in streptomyces reveromyceticus SN-593

10.1021/acssynbio.7b00249 · 2017 · External reference

Comprehensive analyses of cytochrome P450 monooxygenases and secondary metabolite biosynthetic gene clusters in cyanobacteria

10.3390/ijms21020656 · 2020 · External reference

Enhancing isoprenol production by systematically tuning metabolic pathways using CRISPR interference in E. coli

10.3389/fbioe.2023.1296132 · 2023 · External reference

Enhancing terpene yield from sugars via novel routes to 1-Deoxy-D-Xylulose 5-Phosphate

10.1128/aem.02920-14 · 2015 · External reference

Rethinking production of taxol W (paclitaxel) using endophyte

10.1016/j.tibtech.2014.03.011 · 2014 · External reference

A synthetic biology approach to transform Yarrowia lipolytica into a competitive biotechnological producer of β-carotene

10.1002/bit.26473 · 2018 · External reference

Natural transformation of Vibrio natriegens with large genetic cluster enables alginate assimilation for isopentenol production

10.1016/j.biortech.2024.130988 · 2024 · External reference

Heterologous production of α-Carotene in Corynebacterium glutamicum using a multi-copy chromosomal integration method

10.1016/j.biortech.2021.125782 · 2021 · External reference

Enhanced limonene production by metabolically engineered Yarrowia lipolytica from cheap carbon sources

10.1016/j.ces.2021.117342 · 2022 · External reference

Engineering carbon source division of labor for efficient α-carotene production in Corynebacterium glutamicum

10.1016/j.ymben.2024.06.008 · 2024 · External reference

Genome mining of terpene synthases from fourteen

10.3390/microorganisms13071479 · 2025 · External reference

Streptomyces species: ideal chassis for natural product discovery and overproduction

10.1016/j.ymben.2018.05.015 · 2018 · External reference

Engineering the oleaginous yeast Yarrowia lipolytica for production of α-farnesene

10.1186/s13068-019-1636-z · 2019 · External reference

Rewiring energy homeostasis in Yarrowia lipolytica enables efficient terpenoid biosynthesis

10.1016/j.cej.2025.171676 · 2026 · External reference

Pseudomonas putida—a versatile host for the production of natural products

10.1007/s00253-015-6745-4 · 2015 · External reference

Development of Corynebacterium glutamicum as a monoterpene production platform

10.1016/j.ymben.2023.11.009 · 2024 · External reference

Enhancing isoprenoid synthesis in Yarrowia lipolytica by expressing the isopentenol utilization pathway and modulating intracellular hydrophobicity

10.1016/j.ymben.2020.07.010 · 2020 · External reference

Engineering a universal and efficient platform for terpenoid synthesis in yeast

10.1073/pnas.2207680120/ · 2023 · External reference

Compartmentalized orthogonal biosynthesis for boosting limonene and oxygenated monoterpenoid production in Saccharomyces cerevisiae

10.1016/j.biortech.2025.133686 · 2026 · External reference

Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins

10.1186/s12934-015-0241-5 · 2015 · External reference

Modular co-culture engineering of Yarrowia lipolytica for amorphadiene biosynthesis

10.1186/s12934-022-02010-0 · 2022 · External reference

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

10.1038/nbt833 · 2003 · External reference

Quantitative spatial organization facilitates high-level production of β-farnesene in Escherichia coli

10.1016/j.cej.2026.176205 · 2026 · External reference

De novo production of the monoterpenoid geranic acid by metabolically engineered Pseudomonas putida

10.1186/s12934-014-0170-8 · 2014 · External reference

Antibiotic resistance determinants in a Pseudomonas putida strain isolated from a hospital

10.1371/journal.pone.0081604 · 2014 · External reference

Metabolic engineering and synthetic biology for isoprenoid production in Escherichia coli and Saccharomyces cerevisiae

10.1007/s00253-020-11040-w · 2021 · External reference

Effects of different elicitors on terpene production and biological activities of streptomyces sp. PT6

10.1002/ffj.70042 · 2026 · External reference

Advancements in metabolic engineering: enhancing biofuel production through Escherichia coli and Saccharomyces cerevisiae models

10.3390/pr13072115 · 2025 · External reference

Carotenoids from cyanobacteria: biotechnological potential and optimization strategies

10.3390/biom11050735 · 2021 · External reference

Progress in terpene synthesis strategies through engineering of Saccharomyces cerevisiae

10.1080/07388551.2017.1299679 · 2017 · External reference

Heterologous production of squalene from glucose in engineered Corynebacterium glutamicum using multiplex CRISPR interference and high-throughput fermentation

10.1021/acs.jafc.8b05818 · 2019 · External reference

Isoprenoid-based biofuels: homologous expression and heterologous expression in prokaryotes

10.1128/aem.01192-16 · 2016 · External reference

Modulation of culture medium confers high-specificity production of isopentenol in Bacillus subtilis

10.1016/j.jbiosc.2018.10.002 · External reference

In-situ isopentenol production from Bacillus subtilis through genetic and culture condition modulation

10.1016/j.procbio.2018.06.019 · External reference

Biotechnology of isopentenols production from microbial cell factories

10.1016/j.biortech.2025.133574 · 2026 · External reference

Host organism: Pseudomonas putida

10.1002/9783527807796.ch8 · 2017 · External reference

Positioning Bacillus subtilis as terpenoid cell factory

10.1111/jam.14904 · 2021 · External reference

Mapping competitive pathways to terpenoid biosynthesis in synechocystis sp. PCC 6803 using an antisense RNA synthetic tool

10.1186/s12934-023-02040-2 · 2023 · External reference

Studies on the nonmevalonate terpene biosynthetic pathway: metabolic role of IspH (LytB) protein

10.1073/pnas.032658999 · 2002 · External reference

A gram-scale limonene production process with engineered Escherichia coli

10.3390/molecules25081881 · 2020 · External reference

Engineering Corynebacterium glutamicum to produce the biogasoline isopentenol from plant biomass hydrolysates

10.1186/s13068-019-1381-3 · 2019 · External reference

Systematic engineering for high-yield production of viridiflorol and amorphadiene in auxotrophic Escherichia coli

10.1016/j.ymben.2019.07.007 · 2019 · External reference

Metabolic engineering for the biosynthesis of terpenoids from microbial cell factories

10.1007/978-3-031-40082-7_4 · 2023 · External reference

Production of squalene in Bacillus subtilis by squalene synthase screening and metabolic engineering

10.1021/acs.jafc.0c00375 · 2020 · External reference

Engineering of multiple modules to improve amorphadiene production in Bacillus subtilis using CRISPR-Cas9

10.1021/acs.jafc.1c00498 · 2021 · External reference

Multidimensional engineering of Saccharomyces cerevisiae for efficient production of retinol

10.1002/biot.70193 · 2026 · External reference

Production of ultraviolet A protectant C50 carotenoid decaprenoxanthin by metabolically engineered Corynebacterium glutamicum

10.1016/j.biortech.2025.133319 · 2026 · External reference

Orchestrating multiple subcellular organelles of Saccharomyces cerevisiae for efficient production of squalene

10.1016/j.biortech.2025.132294 · 2025 · External reference

Overproduction of α-Farnesene in Saccharomyces cerevisiae by farnesene synthase screening and metabolic engineering

10.1021/acs.jafc.1c00008 · 2021 · External reference

Improving isoprenol production via systematic CRISPRi screening in engineered Escherichia coli

10.1039/d2gc02255a · External reference

Engineering isoprenoids production in metabolically versatile microbial host Pseudomonas putida

10.1186/s13068-022-02235-6 · External reference

Heterologous biosynthesis of terpenoids in Saccharomyces cerevisiae

10.1002/biot.202400712 · 2025 · External reference

Biosynthesis of α-Pinene by genetically engineered Yarrowia lipolytica from low-cost renewable feedstocks

10.1021/acs.jafc.0c06504 · 2021 · External reference

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

10.1073/pnas.1110740109 · 2012 · External reference

Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity

10.1128/aem.00861-07 · 2007 · External reference

Coupling genome-wide continuous perturbation with biosensor screening reveals the potential targets in yeast isopentanol synthesis network

10.1016/j.synbio.2024.12.010 · 2025 · External reference

Vibrio natriegens as a host for rapid biotechnology

10.1016/j.tibtech.2021.10.007 · 2022 · External reference

Paradigm of engineering recalcitrant non-model microorganism with dominant metabolic pathway as a biorefinery chassis

10.1038/s41467-024-54897-5 · 2024 · External reference

Metabolic engineering of Bacillus subtilis for high‐titer production of menaquinone‐7

10.1002/aic.16754 · 2020 · External reference

Photosynthetic conversion of CO2 into pinene using engineered synechococcus sp. PCC 7002

10.3389/fbioe.2021.779437 · 2021 · External reference

Investigation of fermentation conditions of biodiesel by-products for high production of β-farnesene by an engineered Escherichia coli

10.1007/s11356-020-08893-z · 2020 · External reference

High production of triterpenoids in Yarrowia lipolytica through manipulation of lipid components

10.1186/s13068-020-01773-1 · 2020 · External reference

Dynamic regulation and enhancement of synthetic network for efficient biosynthesis of monoterpenoid α-pinene in yeast cell factory

10.1016/j.biortech.2025.132064 · 2025 · External reference

Regulating protein glycosylation modification enhances the synthesis of taxadiene in Saccharomyces cerevisiae

10.1016/j.synbio.2025.12.012 · 2026 · External reference

Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica

10.1016/j.synbio.2026.01.017 · 2026 · External reference

Cytochrome P450s in algae: bioactive natural product biosynthesis and light-driven bioproduction

10.1016/j.apsb.2022.01.013 · 2022 · External reference

Green biosynthesis of terpenoid-derived flavor and fragrance compounds: advances and strategic perspectives

10.1021/acs.jafc.5c08719 · 2026 · External reference

The TfoX revolution: a review of genetic engineering in Vibrio natriegens

10.1016/j.copbio.2026.103506 · 2026 · External reference

Engineering Cyanobacteria as a new platform for producing taxol precursors directly from carbon dioxide

10.1186/s13068-024-02555-9 · 2024 · External reference

Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production

10.1186/1475-2859-11-148 · External reference

Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production

10.1371/journal.pone.0047513 · External reference

Optimization of amorphadiene synthesis in Bacillus subtilis via transcriptional, translational, and media modulation

10.1002/bit.24900 · 2013 · External reference

A Ribulose-5-phosphate shunt from the calvin–benson cycle to methylerythritol phosphate pathway for enhancing photosynthetic terpenoid production

10.1021/acssynbio.3c00675 · 2024 · External reference