Research graph
References from Artificial-intelligence- and multi-omics-guided predictive and drug repurposing framework construction for colorectal cancer: evidence from succinylation–neutrophil signatures. Local targets link to admitted publications; unresolved targets remain external evidence.
SCENITH: a flow cytometry-based method to functionally profile energy metabolism with single-cell resolution
10.1016/j.cmet.2020.11.007 · 2020 · External reference
Relative α1-anti-trypsin deficiency in systemic sclerosis
10.1093/rheumatology/ker123 · 2011 · External reference
Immune response in colorectal carcinoma: a review of its significance as a predictive and prognostic biomarker
10.1111/his.14713 · 2022 · External reference
Interval colorectal carcinoma: an unsolved debate
10.3748/wjg.v21.i45.12735 · 2015 · External reference
Integrating single-cell transcriptomic data across different conditions, technologies, and species
10.1038/nbt.4096 · 2018 · External reference
Neutrophils in atopic dermatitis
10.1007/s12016-024-09004-3 · 2024 · External reference
GEOquery: a bridge between the gene expression omnibus (GEO) and BioConductor
10.1093/bioinformatics/btm254 · 2007 · External reference
Single-cell sequencing unveils mitophagy-related prognostic model for triple-negative breast cancer
10.3389/fimmu.2024.1489444 · 2024 · External reference
NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumors
10.1158/0008-5472.can-19-3158 · 2020 · External reference
SUCLG2 regulates mitochondrial dysfunction through succinylation in lung adenocarcinoma
10.1002/advs.202303535 · 2023 · External reference
Lactate-upregulated NADPH-Dependent NOX4 expression via HCAR1/PI3K pathway contributes to ROS-induced osteoarthritis chondrocyte damage
10.1016/j.redox.2023.102867 · 2023 · External reference
A multi-dimensional approach to unravel the intricacies of lactylation related signature for prognostic and therapeutic insight in colorectal cancer
10.1186/s12967-024-04955-9 · External reference
Identification of novel biomarkers related to neutrophilic inflammation in COPD
10.3389/fimmu.2024.1410158 · External reference
Succinylation-related molecular activities in cancer: metabolic adaptations, immune landscape, and prognostic significance in colorectal cancer
10.3389/fimmu.2025.1571446 · 2025 · External reference
Inference and analysis of cell-cell communication using CellChat
10.1038/s41467-021-21246-9 · 2021 · External reference
Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression
10.1186/s13046-023-02817-8 · 2023 · External reference
WGCNA: an R package for weighted correlation network analysis
10.1186/1471-2105-9-559 · 2008 · External reference
The sva package for removing batch effects and other unwanted variation in high-throughput experiments
10.1093/bioinformatics/bts034 · 2012 · External reference
Pan cancer research reveals the role of PTGDS in tumor suppression and immune regulation
10.1038/s41698-025-01097-z · 2025 · External reference
Self-organizing map algorithm for assessing spatial and temporal patterns of pollutants in environmental compartments: a review
10.1016/j.scitotenv.2023.163084 · 2023 · External reference
Talazoparib in patients with advanced breast cancer and a germline BRCA mutation
10.1056/nejmoa1802905 · 2018 · External reference
Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer
10.1016/j.ccell.2025.12.003 · 2026 · External reference
scTenifoldKnk: an efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation
10.1016/j.patter.2022.100434 · 2022 · External reference
Self-organizing map improves understanding on the hydrochemical processes in aquifer systems
10.1016/j.scitotenv.2022.157281 · 2022 · External reference
Limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
Second version of the prostate cancer molecular imaging standardized evaluation framework including response evaluation for clinical trials (PROMISE V2)
10.1016/j.eururo.2023.02.002 · 2023 · External reference
Lysine succinylation, the metabolic bridge between cancer and immunity
10.1016/j.gendis.2022.10.028 · 2023 · External reference
SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
10.1016/j.molcel.2021.04.002 · 2021 · External reference
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy
10.1038/s41698-024-00538-5 · 2024 · External reference
Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence
10.3389/fimmu.2024.1427626 · 2024 · External reference
Metabolism-driven posttranslational modifications and immune regulation: emerging targets for immunotherapy
10.1126/sciadv.adx6489 · 2025 · External reference
Identification and validation of immune and oxidative stress-related diagnostic markers for diabetic nephropathy by WGCNA and machine learning
10.3389/fimmu.2023.1084531 · 2023 · External reference
Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer
10.1186/s12964-025-02176-1 · 2025 · External reference
Single-cell Mayo map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis
10.1186/s12915-023-01728-6 · 2023 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
2012 · External reference
Multi-cohort validation of a lipid metabolism and ferroptosis-associated index for prognosis and immunotherapy response prediction in hormone receptor-positive breast cancer
10.7150/ijbs.113213 · External reference
Training and experimental validation a novel anoikis- and epithelial‒mesenchymal transition-related signature for evaluating prognosis and predicting immunotherapy efficacy in gastric cancer
10.7150/jca.106029 · External reference
Succinylation-associated lncRNA signature to predict the prognosis of colon cancer based on integrative bioinformatics analysis
10.1038/s41598-023-34503-2 · 2023 · External reference
A multi-omic machine learning approach deconstructs the role of amino acid metabolism in the immune microenvironment and prognosis of colon adenocarcinoma
10.3389/fimmu.2025.1719555 · 2025 · External reference
Identification of aging-related biomarkers and immune infiltration characteristics in osteoarthritis based on bioinformatics analysis and machine learning
10.3389/fimmu.2023.1168780 · 2023 · External reference
Kinic index: an artificial intelligence-driven predictive model and multitarget drug discovery framework for hepatocellular carcinoma patients
10.1038/s41698-026-01324-1 · 2026 · External reference
NOX4 suppresses ferroptosis through regulation of the pentose phosphate pathway in colorectal cancer
10.1007/s11596-025-00013-7 · 2025 · External reference
