Research graph
References from Advances in research on hyperoxia-induced acute lung injury: from pathogenesis to therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Unlocking the protective potential of the angiotensin type 2 receptor (AT2R) in acute lung injury and age-related pulmonary dysfunction
10.1016/j.bcp.2023.115978 · 2024 · External reference
Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis
10.1016/j.bja.2021.10.039 · 2022 · External reference
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries
10.1042/cs20170157 · 2017 · External reference
Depolarized mitochondrial membrane potential and protection with duroquinone in isolated perfused lungs from rats exposed to hyperoxia
10.1152/japplphysiol.00565.2021 · 2022 · External reference
Hyperoxemia after reperfusion in cardiac arrest patients: a potential dose–response association with 30-day survival
10.1186/s13054-023-04379-9 · 2023 · External reference
Vascular endothelial growth factors and vascular permeability
10.1093/cvr/cvq105 · 2010 · External reference
Simvastatin decreases hyperoxic oxygen-induced acute lung injury by upregulating eNOS
10.1152/ajplung.00520.2016 · 2018 · External reference
Oxidative stress and inflammation in acute and chronic lung injuries
10.3390/antiox12030548 · 2023 · External reference
Epithelial cell death is an important contributor to oxidant-mediated acute lung injury
10.1164/rccm.201002-0181oc · 2011 · External reference
Oxygen-mediated lung injury in mice lacking the gene for NRF2: rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects
10.1016/j.freeradbiomed.2020.07.027 · 2020 · External reference
Roflumilast, a phosphodiesterase-4 inhibitor, improves hyperoxia-induced lung injury via anti-inflammation
10.22462/04.06.2020.3 · 2020 · External reference
NF-κB: blending metabolism, immunity, and inflammation
10.1016/j.it.2022.07.004 · 2022 · External reference
Effects of hyperoxemia in patients with sepsis - a post-hoc analysis of a multicentre randomized clinical trial
10.1016/j.pulmoe.2023.02.005 · 2025 · External reference
The role of Interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress syndrome
10.3389/fphar.2021.808797 · 2021 · External reference
The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction
10.1038/sj.cdd.4401148 · 2003 · External reference
Suppression of plasminogen activator inhibitor-1 by inhaled nitric oxide attenuates the adverse effects of hyperoxia in a rat model of acute lung injury
10.1016/j.thromres.2015.04.018 · 2015 · External reference
Tn (N-acetyl-d-galactosamine-O-serine/threonine) immunization protects against hyperoxia-induced lung injury in adult mice through inhibition of the nuclear factor kappa B activity
10.1016/j.intimp.2018.04.022 · 2018 · External reference
RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease
10.1172/jci.insight.144689 · 2021 · External reference
Reduction of hyperoxic acute lung injury in mice by formononetin
10.1371/journal.pone.0245050 · 2021 · External reference
Engineered extracellular vesicles carrying let-7a-5p for alleviating inflammation in acute lung injury
10.1186/s12929-024-01019-4 · 2024 · External reference
Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice
10.1016/j.taap.2018.12.004 · 2019 · External reference
A high-fiber diet or dietary supplementation of acetate attenuate hyperoxia-induced acute lung injury
10.3390/nu14245231 · 2021 · External reference
Enhanced resolution of hyperoxic acute lung injury as a result of aspirin triggered resolvin D1 treatment
10.1165/rcmb.2014-0339oc · 2015 · External reference
HIF1, HSF1, and NRF2: oxidant-responsive trio raising cellular defenses and engaging immune system
10.1021/acs.chemrestox.2c00131 · 2022 · External reference
Reactive oxygen species: a novel antimicrobial
10.1016/j.ijantimicag.2017.08.029 · 2018 · External reference
ROS induced lipid peroxidation and their role in ferroptosis
10.3389/fcell.2023.1226044 · 2023 · External reference
Angiotensin-converting enzyme 2 attenuates inflammatory response and oxidative stress in hyperoxic lung injury by regulating NF-κB and Nrf2 pathways
10.1093/qjmed/hcz206 · 2019 · External reference
NLRP3 deletion protects from hyperoxia-induced acute lung injury
10.1152/ajpcell.00086.2013 · 2013 · External reference
Deletion of ASK1 protects against hyperoxia-induced acute lung injury
10.1371/journal.pone.0147652 · 2016 · External reference
Adenovirus-mediated transfer of the SOCS-1 gene to mouse lung confers protection against hyperoxic acute lung injury
10.1016/j.freeradbiomed.2015.03.036 · 2015 · External reference
Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression
10.1152/ajplung.00417.2015 · 2016 · External reference
GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation
10.1016/j.redox.2023.102614 · 2023 · External reference
Alpha-klotho enrichment in induced pluripotent stem cell secretome contributes to antioxidative protection in acute lung injury
10.1002/stem.2752 · 2018 · External reference
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
10.1038/s41586-023-06089-2 · 2023 · External reference
Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages
10.1038/s41467-021-27428-9 · 2021 · External reference
Salidroside attenuates HALI via IL-17A-mediated ferroptosis of alveolar epithelial cells by regulating Act1-TRAF6-p38 MAPK pathway
10.1186/s12964-022-00994-1 · 2022 · External reference
FAM134B deletion exacerbates apoptosis and epithelial-to-mesenchymal transition in rat lungs exposed to hyperoxia
10.1016/j.isci.2024.110385 · 2024 · External reference
Biocompatible and size-dependent melanin-like nanocapsules for efficient therapy in hyperoxia-induced acute lung injury
10.1016/j.biomaterials.2025.123169 · 2025 · External reference
PINK1-PRKN mediated mitophagy: differences between in vitro and in vivo models
10.1080/15548627.2022.2139080 · 2023 · External reference
NOX4 mediates epithelial cell death in hyperoxic acute lung injury through mitochondrial reactive oxygen species
10.3389/fphar.2022.880878 · 2022 · External reference
Targeting PI3K/Akt signal transduction for cancer therapy
10.1038/s41392-021-00828-5 · 2021 · External reference
BMI1 silencing induces mitochondrial dysfunction in lung epithelial cells exposed to hyperoxia
10.3389/fphys.2022.814510 · 2022 · External reference
The p53-activated gene, PAG608, requires a zinc finger domain for nuclear localization and oxidative stress-induced apoptosis
10.1074/jbc.m203594200 · 2002 · External reference
Attenuation of hyperoxic acute lung injury by Lycium barbarum polysaccharide via inhibiting NLRP3 inflammasome
10.1007/s12272-019-01175-4 · 2019 · External reference
Interleukin-3 plays a vital role in hyperoxic acute lung injury in mice via mediating inflammation
10.1186/s12890-018-0725-2 · 2018 · External reference
Sigma-1 receptor regulates the endoplasmic reticulum stress pathway in the protective mechanism of dexmedetomidine against hyperoxia-induced lung injury
10.1016/j.bbadis.2023.166885 · 2024 · External reference
A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
10.1093/emboj/16.14.4384 · 1997 · External reference
Hyperoxemia in mechanically ventilated, critically ill subjects: incidence and related factors
10.4187/respcare.03451 · 2015 · External reference
Etomidate attenuates hyperoxia-induced acute lung injury in mice by modulating the Nrf2/HO-1 signaling pathway
10.3892/etm.2021.10217 · 2021 · External reference
13-Methylpalmatine improves myocardial infarction injury by inhibiting CHOP-Mediated cross-talk between endoplasmic reticulum and mitochondria
10.1016/j.biopha.2024.117342 · 2024 · External reference
Oxygen pneumonitis in man
10.1378/chest.62.2.162 · 1972 · External reference
Probucol attenuates hyperoxia-induced lung injury in mice
10.1371/journal.pone.0175129 · 2017 · External reference
The role of pattern-recognition receptors in innate immunity: update on toll-like receptors
10.1038/ni.1863 · 2010 · External reference
The NLRP3 inflammasome: an overview of mechanisms of activation and regulation
10.3390/ijms20133328 · 2019 · External reference
Macrophages in wound healing: activation and plasticity
10.1111/imcb.12236 · 2019 · External reference
NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury
10.1038/s41598-023-28206-x · 2023 · External reference
Efficiency of exogenous surfactant combined with intravenous N-acetylcysteine in two-hit rodent model of ARDS
10.1016/j.resp.2023.104138 · 2023 · External reference
Combination of pioglitazone, a PPARγ agonist, and synthetic surfactant B-YL prevents hyperoxia-induced lung injury in adult mice lung explants
10.1016/j.pupt.2023.102209 · 2023 · External reference
Toll-like receptors in transplantation: sensing and reacting to injury
10.1038/ki.2011.498 · 2012 · External reference
Activation of src-dependent Smad3 signaling mediates the neutrophilic inflammation and oxidative stress in hyperoxia-augmented ventilator-induced lung injury
10.1186/s12931-015-0275-6 · 2015 · External reference
Exogenous interleukin‐10 attenuates hyperoxia‐induced acute lung injury in mice
10.1113/expphysiol.2014.083337 · 2015 · External reference
Inhibition of src and forkhead box O1 signaling by induced pluripotent stem-cell therapy attenuates hyperoxia-augmented ventilator-induced diaphragm dysfunction
10.1016/j.trsl.2016.03.011 · 2016 · External reference
miR-16 inhibits hyperoxia-induced cell apoptosis in human alveolar epithelial cells
10.3892/mmr.2018.8636 · 2018 · External reference
Effect of soluble epoxide hydrolase in hyperoxic acute lung injury in mice
10.1007/s10753-018-0758-y · 2018 · External reference
Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62–Keap1–NRF2 pathway
10.1186/s11658-022-00383-z · 2022 · External reference
Wedelolactone inhibits ferroptosis and alleviates hyperoxia-induced acute lung injury via the Nrf2/HO-1 signaling pathway
10.1093/toxsci/kfae099 · 2024 · External reference
Emerging mechanisms of ferroptosis and its implications in lung cancer
10.1097/cm9.0000000000003048 · 2024 · External reference
High tidal volume induces mitochondria damage and releases mitochondrial DNA to aggravate the ventilator-induced lung injury
10.3389/fimmu.2018.01477 · 2018 · External reference
Role of cytochrome P450 (CYP)1A in hyperoxic lung injury: analysis of the transcriptome and proteome
10.1038/s41598-017-00516-x · 2017 · External reference
Therapeutic characteristics of alveolar-like macrophages in mouse models of hyperoxia and LPS-Induced lung inflammation
10.1152/ajplung.00270.2023 · 2024 · External reference
Deletion of soluble epoxide hydrolase attenuates mice hyperoxic acute lung injury
10.1186/s12871-018-0490-z · 2018 · External reference
Quantitative proteomics reveals the mechanisms of hydrogen-conferred protection against hyperoxia-induced injury in type II alveolar epithelial cells
10.1080/01902148.2019.1601296 · 2018 · External reference
Theaflavin-3,3’-digallate attenuates cigarette smoke extract-induced pulmonary emphysema in mice by suppressing necroptosis
10.3892/etm.2021.10933 · 2022 · External reference
Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approaches
10.1007/s40262-019-00783-z · 2019 · External reference
Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation
10.1152/japplphysiol.00539.2011 · 2011 · External reference
Pathological changes of the lungs after prolonged inhalation of high concentrations of oxygen
10.1007/bf00705300 · 1986 · External reference
CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice
10.3389/fimmu.2020.566953 · 2020 · External reference
NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of Interleukin-1β
10.1074/jbc.m114.603217 · 2015 · External reference
Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway
10.1038/cddis.2015.282 · 2015 · External reference
miR-20b suppresses mitochondrial dysfunction-mediated apoptosis to alleviate hyperoxia-induced acute lung injury by directly targeting MFN1 and MFN2
10.1093/abbs/gmaa161 · 2020 · External reference
Deleterious role of TLR3 during hyperoxia-induced acute lung injury
10.1164/rccm.200807-1020oc · 2008 · External reference
NLRX1 is a multifaceted and enigmatic regulator of immune system function
10.3389/fimmu.2019.02419 · 2019 · External reference
Akap1genetic deletion increases the severity of hyperoxia-induced acute lung injury in mice
10.1152/ajplung.00365.2017 · 2018 · External reference
Nitrated fatty acid, 10-nitrooleate protects against hyperoxia-induced acute lung injury in mice
10.1016/j.intimp.2022.108838 · 2022 · External reference
Pulmonary lesions associated with oxygen therapy and artificial ventilation
10.1056/nejm196702162760702 · 1967 · External reference
Nrf2 and oxidative stress: a general overview of mechanisms and implications in human disease
10.3390/antiox11122345 · 2022 · External reference
Mitochondrial complex I ROS production and redox signaling in hypoxia
10.1016/j.redox.2023.102926 · 2023 · External reference
ROS production by mitochondria: function or dysfunction?
10.1038/s41388-023-02907-z · 2024 · External reference
Suppression of endoplasmic reticulum stress by 4-PBA protects against hyperoxia-induced acute lung injury via Up-Regulating Claudin-4 expression
10.3389/fimmu.2021.674316 · 2021 · External reference
Development of organoid-based drug metabolism model
10.1016/j.taap.2019.114790 · 2019 · External reference
Dietary antioxidants significantly attenuate hyperoxia-induced acute inflammatory lung injury by enhancing macrophage function via reducing the accumulation of airway HMGB1
10.3390/ijms21030977 · 2020 · External reference
Alda-1 attenuates hyperoxia-induced mitochondrial dysfunction in lung vascular endothelial cells
10.18632/aging.102012 · 2019 · External reference
Sirtuin 1 promotes hyperoxia-induced lung epithelial cell death independent of NF-E2–Related factor 2 activation
10.1165/rcmb.2014-0056oc · 2016 · External reference
miR-21-5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AECII cells via PTEN/AKT signaling in rats
10.3892/mmr.2019.10779 · 2019 · External reference
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism
10.1016/j.celrep.2023.112745 · 2023 · External reference
ROS-Mediated MAPK activation aggravates hyperoxia-induced acute lung injury by promoting apoptosis of type II alveolar epithelial cells via the STAT3/miR-21–5p axis
10.1016/j.molimm.2023.09.016 · 2023 · External reference
Thioredoxin prevents loss of UCP2 in hyperoxia via MKK4–p38 MAPK–PGC1α signaling and limits oxygen toxicity
10.1165/rcmb.2021-0219oc · 2022 · External reference
Nanoparticle facilitated inhalational delivery of erythropoietin receptor cDNA protects against hyperoxic lung injury
10.1016/j.nano.2015.10.004 · 2016 · External reference
Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice
10.4049/jimmunol.0804248 · 2009 · External reference
PI3K-AKT signaling via Nrf2 protects against hyperoxia-induced acute lung injury, but promotes inflammation post-injury independent of Nrf2 in mice
10.1371/journal.pone.0129676 · 2015 · External reference
VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury
10.1002/path.4708 · 2016 · External reference
Arterial oxygen tensions in mechanically ventilated ICU patients and mortality: a retrospective, multicentre, observational cohort study
10.1016/j.bja.2019.12.039 · 2020 · External reference
Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins
10.1152/ajplung.00121.2017 · 2017 · External reference
SPAK-p38 MAPK signal pathway modulates claudin-18 and barrier function of alveolar epithelium after hyperoxic exposure
10.1186/s12890-021-01408-7 · 2021 · External reference
Arterial oxygen and carbon dioxide tension and acute brain injury in extracorporeal cardiopulmonary resuscitation patients: analysis of the extracorporeal life support organization registry
10.1016/j.healun.2022.10.019 · 2023 · External reference
Mitochondrial protein Akap1 deletion exacerbates endoplasmic reticulum stress in mice exposed to hyperoxia
10.3389/fphar.2022.762840 · 2022 · External reference
Dangers of hyperoxia
10.1186/s13054-021-03815-y · 2021 · External reference
The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation
10.1186/s10020-020-00177-z · 2020 · External reference
GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice
10.1038/s41598-022-27201-y · 2023 · External reference
A-Kinase anchor protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury
10.3389/fphar.2022.980723 · 2022 · External reference
Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1
10.1080/10715762.2017.1351027 · 2017 · External reference
Multienzyme active melanin nanodots for antioxidant-immunomodulatory therapy of hyperoxia lung injury
10.1016/j.mtbio.2025.101609 · 2025 · External reference
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis
10.1152/ajplung.00320.2018 · 2019 · External reference
Bcl-2 family proteins as regulators of oxidative stress
10.1016/j.semcancer.2008.12.002 · 2009 · External reference
Protective effect of SIRT3 on acute lung injury by increasing manganese superoxide dismutase-mediated antioxidation
10.3892/mmr.2018.8469 · 2018 · External reference
Ambient ozone exposure induces ROS related-mitophagy and pyroptosis via NLRP3 inflammasome activation in rat lung cells
10.1016/j.ecoenv.2022.113663 · 2022 · External reference
Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia
10.1038/s41598-021-89210-7 · 2021 · External reference
Aspirin attenuates hyperoxia-induced acute respiratory distress syndrome (ARDS) by suppressing pulmonary inflammation via the NF-κB signaling pathway
10.3389/fphar.2021.793107 · 2021 · External reference
Mice lacking the cytochrome P450 1B1 gene are less susceptible to hyperoxic lung injury than wild type
10.1093/toxsci/kfy154 · 2018 · External reference
ZJ01, a small molecule inhibitor of the kelch-like ECH-associated protein 1-Nuclear factor erythroid 2-Related factor 2 (Keap1-Nrf2) protein-protein interaction, reduces hyperoxic acute lung injury in a mouse model
10.12659/msm.920467 · 2020 · External reference
Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury
10.1016/j.freeradbiomed.2015.01.019 · 2015 · External reference
Anti-fibrotic potential of AT2 receptor agonists
10.3389/fphar.2017.00564 · 2017 · External reference
Porcine CXCR1/2 antagonist CXCL8(3–72)G31P inhibits lung inflammation in LPS-Challenged mice
10.1038/s41598-020-57737-w · 2020 · External reference
Lung injury induced by short-term mechanical ventilation with hyperoxia and its mitigation by deferoxamine in rats
10.1186/s12871-020-01089-5 · 2020 · External reference
A bifunctional antibody targeting PD-1 and TGF-β signaling has antitumor activity in combination with radiotherapy and attenuates radiation-induced lung injury
10.1158/2326-6066.cir-23-0903 · 2025 · External reference
Lung protection by inhalation of exogenous solubilized extracellular matrix
10.1371/journal.pone.0171165 · 2017 · External reference
Bone marrow mesenchymal stem cell-derived exosomes alleviate hyperoxia-induced lung injury via the manipulation of microRNA-425
10.1016/j.abb.2020.108712 · 2021 · External reference
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis
10.1038/s43018-021-00262-0 · 2021 · External reference
Polystyrene nanoplastics-induced lung apoptosis and ferroptosis via ROS-Dependent endoplasmic reticulum stress
10.1016/j.scitotenv.2023.169260 · 2024 · External reference
Advances in the study of macrophage polarization in inflammatory immune skin diseases
10.1186/s12950-023-00360-z · 2023 · External reference
Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy
10.1038/s41420-023-01407-z · 2023 · External reference
Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis
10.1186/s13017-021-00363-2 · 2021 · External reference
ETS1 ameliorates hyperoxia-induced bronchopulmonary dysplasia in mice by activating Nrf2/HO-1 mediated ferroptosis
10.1007/s00408-023-00639-1 · 2023 · External reference
Lactoferrin protects hyperoxia-induced lung and kidney systemic inflammation in an in vivo imaging model of NF-κB/Luciferase transgenic mice
10.1007/s11307-019-01390-x · 2020 · External reference
A standardized botanical composition mitigated acute inflammatory lung injury and reduced mortality through extracellular HMGB1 reduction
10.3390/molecules28186560 · 2023 · External reference
IgG is an aging factor that drives adipose tissue fibrosis and metabolic decline
10.1016/j.cmet.2024.01.015 · 2024 · External reference
AECII-Derived miR-21a-5p exosomes alleviate HALI via targeting and regulating PGAM5-mediated necroptosis
10.1016/j.cellsig.2025.111677 · 2025 · External reference
Bax and the mitochondrial permeability transition cooperate in the release of cytochrome c during endoplasmic reticulum-stress-induced apoptosis
10.1038/sj.cdd.4402072 · 2007 · External reference
PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury
10.1152/ajplung.00598.2020 · 2021 · External reference
An endothelial Hsp70-TLR4 axis limits Nox3 expression and protects against oxidant injury in lungs
10.1089/ars.2015.6505 · 2016 · External reference
miR-185 mediates lung epithelial cell death after oxidative stress
10.1152/ajplung.00392.2015 · 2016 · External reference
Endothelial stanniocalcin 1 maintains mitochondrial bioenergetics and prevents oxidant-induced lung injury via toll-like receptor 4
10.1089/ars.2018.7514 · 2019 · External reference
Sirtuins and their biological relevance in aging and age-related diseases
10.14336/ad.2019.0820 · 2020 · External reference
Nicotinamide mononucleotide mitigates hyperoxia-aggravated septic lung injury via the GPx4-mediated anti-ferroptosis signaling pathway in alveolar epithelial cells
10.1016/j.freeradbiomed.2025.04.021 · 2025 · External reference
Lycium barbarum polysaccharide reduces hyperoxic acute lung injury in mice through Nrf2 pathway
10.1016/j.biopha.2018.12.073 · 2019 · External reference
Toll-like receptor 7 deficiency mitigates hyperoxia-induced acute lung injury in mice
10.1016/j.biopha.2020.110345 · External reference
Inflammasome activation and regulation: toward a better understanding of complex mechanisms
10.1038/s41421-020-0167-x · External reference
TRPM2 links oxidative stress to NLRP3 inflammasome activation
10.1038/ncomms2608 · 2013 · External reference
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction
10.1177/1535370220975106 · 2021 · External reference
Oxidative stress promotes lipid-laden macrophage formation via CYP1B1
10.1016/j.redox.2024.103481 · 2025 · External reference
K2P2.1 (TREK-1) potassium channel activation protects against hyperoxia-induced lung injury
10.1038/s41598-020-78886-y · 2020 · External reference