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References from Mechanical observables of cancer invasion: actin, adhesion, and metastatic plasticity. Local targets link to admitted publications; unresolved targets remain external evidence.
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
10.1016/j.cell.2014.07.013 · 2014 · External reference
Physical models of collective cell migration
10.1146/annurev-conmatphys-031218-013516 · 2020 · External reference
Glass-like dynamics of collective cell migration
10.1073/pnas.1010059108 · 2011 · External reference
Three-dimensional topological defects and quasi-long-range order in biological liquid crystals
10.1101/2025.04.14.648711 · 2025 · External reference
Epithelia are multiscale active liquid crystals
10.1038/s41567-023-02179-0 · 2023 · External reference
Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration
10.1186/1741-7007-9-54 · 2011 · External reference
Preclinical to clinical utility of ROCK inhibitors in cancer
10.1016/j.trecan.2022.12.001 · 2023 · External reference
Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy
10.1038/s41467-025-59584-7 · 2025 · External reference
Fibroblasts generate topographical cues that steer cancer cell migration
10.1126/sciadv.ade2120 · 2023 · External reference
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer
10.1038/s41388-022-02420-9 · 2022 · External reference
A density-independent rigidity transition in biological tissues
10.1038/nphys3471 · 2015 · External reference
Motility-driven glass and jamming transitions in biological tissues
10.1103/physrevx.6.021011 · 2016 · External reference
Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches
10.1016/j.cels.2016.01.003 · 2016 · External reference
Compressive stress drives adhesion-dependent unjamming transitions in breast cancer cell migration
10.3389/fcell.2022.933042 · 2022 · External reference
Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer
10.1172/jci93172 · 2017 · External reference
Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations
10.1038/s41592-024-02241-6 · 2024 · External reference
Blebs lead the way: how to migrate without lamellipodia
10.1038/nrm2453 · 2008 · External reference
Confined cell migration along extracellular matrix space in vivo
10.1073/pnas.2414009121 · 2025 · External reference
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
10.1038/s41467-022-31340-1 · 2022 · External reference
Intravital imaging of cell movement in tumours
10.1038/nrc1231 · 2003 · External reference
Aligned collagen is a prognostic signature for survival in human breast carcinoma
10.1016/j.ajpath.2010.11.076 · 2011 · External reference
Cell migration and invasion in human disease: the tks adaptor proteins
10.1042/bst20110685 · 2012 · External reference
Model for adhesion clutch explains biphasic relationship between actin flow and traction at the cell leading edge
10.1088/1478-3975/12/3/035002 · 2015 · External reference
Rho GTPase signaling in cancer progression and dissemination
10.1152/physrev.00045.2020 · 2022 · External reference
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration
10.1038/s41467-023-38292-0 · 2023 · External reference
AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion
10.1091/mbc.e16-05-0286 · 2016 · External reference
Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments
10.1007/s12195-014-0342-y · 2014 · External reference
Genomic signatures of the unjamming transition in compressed human bronchial epithelial cells
10.1126/sciadv.abf1088 · 2021 · External reference
Stretching single talin rod molecules activates vinculin binding
10.1126/science.1162912 · 2009 · External reference
Nuclear envelope rupture and repair during cancer cell migration
10.1126/science.aad7297 · 2016 · External reference
Induced Arp2/3 complex depletion increases FMNL2/3 formin expression and filopodia formation
10.3389/fcell.2021.634708 · 2021 · External reference
Phosphorylation of INF2 by AMPK promotes mitochondrial fission and oncogenic function in endometrial cancer
10.1038/s41419-024-06431-0 · 2024 · External reference
Channeling the force: PIEZO1 mechanotransduction in cancer metastasis
10.3390/cells10112815 · 2021 · External reference
Proteolysis-free amoeboid migration of melanoma cells through crowded environments via bleb-driven worrying
10.1016/j.devcel.2024.05.024 · 2024 · External reference
Twist1-induced invadopodia formation promotes tumor metastasis
10.1016/j.ccr.2011.01.036 · 2011 · External reference
Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density
10.1038/s41467-023-41449-6 · 2023 · External reference
Force triggers YAP nuclear entry by regulating transport across nuclear pores
10.1016/j.cell.2017.10.008 · 2017 · External reference
Rho GTPases in cell biology
10.1038/nature01148 · 2002 · External reference
Organizing the cell cortex: the role of ERM proteins
10.1038/nrm2866 · 2010 · External reference
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
10.1038/nature15748 · 2015 · External reference
Hemodynamic forces tune the arrest, adhesion, and extravasation of circulating tumor cells
10.1016/j.devcel.2018.02.015 · 2018 · External reference
Tumour-cell invasion and migration: diversity and escape mechanisms
10.1038/nrc1075 · 2003 · External reference
Plasticity of cell migration: a multiscale tuning model
10.1083/jcb.200909003 · 2010 · External reference
Rigid tumours contain soft cancer cells
10.1038/s41567-022-01755-0 · 2022 · External reference
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
10.1038/ncb1658 · 2007 · External reference
Migrastatics—Anti-metastatic and anti-invasion drugs: promises and challenges
10.1016/j.trecan.2017.04.008 · 2017 · External reference
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed
10.1083/jcb.200810060 · 2008 · External reference
Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
10.1038/ncb1973 · 2009 · External reference
State of cell unjamming correlates with distant metastasis in cancer patients
10.1103/physrevx.13.031003 · 2023 · External reference
Self organisation of invasive breast cancer driven by the interplay of active and passive nematic dynamics
10.1101/2024.12.09.626295 · 2024 · External reference
Tumor budding: the name is EMT. Partial EMT
10.3390/jcm5050051 · 2016 · External reference
Cell and nucleus shape as an indicator of tissue fluidity in carcinoma
10.1103/physrevx.11.011033 · 2021 · External reference
Tension-induced cytokinetic abscission in human fibroblasts
10.18632/oncotarget.24016 · 2018 · External reference
Septin and ras regulate cytokinetic abscission in detached cells
10.1186/s13008-019-0051-y · 2019 · External reference
DIAPH3 governs the cellular transition to the amoeboid tumour phenotype
10.1002/emmm.201200242 · 2012 · External reference
Rho GTPases and the actin cytoskeleton
10.1126/science.279.5350.509 · 1998 · External reference
Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, β1-integrin function, and migration strategies
2002 · External reference
Formin proteins FHOD1 and INF2 in triple-negative breast cancer: association with basal markers and functional activities
10.1177/1178223418792247 · 2018 · External reference
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
10.1038/ncb2133 · 2011 · External reference
Determining optical flow
10.1016/0004-3702(81)90024-2 · 1981 · External reference
Exosome secretion is enhanced by invadopodia and drives invasive behavior
10.1016/j.celrep.2013.10.050 · 2013 · External reference
Modeling the transitions between collective and solitary migration phenotypes in cancer metastasis
10.1038/srep17379 · 2015 · External reference
Cell-cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion
10.1038/s41556-020-0552-6 · 2020 · External reference
Integrin signaling via FAK-src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody
10.18632/oncotarget.9003 · 2016 · External reference
Cell cycle regulation by integrin-mediated adhesion
10.3390/cells11162521 · External reference
Integrin-mediated adhesion promotes centrosome separation in early mitosis
10.3390/cells11081360 · External reference
F-actin, a model polymer for semiflexible chains in dilute, semidilute, and liquid crystalline solutions
10.1016/s0006-3495(96)79630-3 · 1996 · External reference
Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS
10.1182/blood-2014-01-552463 · 2014 · External reference
A YAP-Centered mechanotransduction loop drives collective breast cancer cell invasion
10.1038/s41467-024-49230-z · 2024 · External reference
Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin
10.1091/mbc.e12-12-0857 · 2013 · External reference
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment
10.1038/s41388-022-02258-1 · 2022 · External reference
Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin
10.1038/s41467-019-13213-2 · 2019 · External reference
A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion
10.1038/ncb3478 · 2017 · External reference
Mechanobiology of collective cell behaviours
10.1038/nrm.2017.98 · 2017 · External reference
Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration
10.1038/s41467-021-25916-6 · 2021 · External reference
Rho GTPase signaling complexes in cell migration and invasion
10.1083/jcb.201612069 · 2018 · External reference
Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner
10.1083/jcb.201001149 · 2010 · External reference
Matrix crosslinking forces tumor progression by enhancing integrin signaling
10.1016/j.cell.2009.10.027 · 2009 · External reference
Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration
10.7554/elife.08314 · 2015 · External reference
Recommendations for reporting tumor budding in colorectal cancer based on the international tumor budding consensus conference (ITBCC) 2016
10.1038/modpathol.2017.46 · 2017 · External reference
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway
10.1083/jcb.201103045 · 2011 · External reference
Rapid cancer cell perineural invasion utilizes amoeboid migration
10.1073/pnas.2210735120 · 2023 · External reference
Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression
10.1186/1476-4598-10-75 · 2011 · External reference
In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
10.1038/s41467-020-18841-7 · 2020 · External reference
Cell motility driven by actin polymerization
10.1016/s0006-3495(96)79496-1 · 1996 · External reference
Cancer cells resist mechanical destruction in circulation via RhoA/Actomyosin-Dependent mechano-adaptation
10.1016/j.celrep.2020.02.080 · 2020 · External reference
Mitotic microhomology-mediated break-induced replication promotes chromoanasynthesis
10.1038/s41467-026-70086-y · 2026 · External reference
Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
10.7554/elife.58688 · 2021 · External reference
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
10.1083/jcb.200812176 · 2009 · External reference
E-cadherin is required for metastasis in multiple models of breast cancer
10.1038/s41586-019-1526-3 · 2019 · External reference
Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma
10.1038/s41563-019-0425-1 · 2019 · External reference
Unjamming and cell shape in the asthmatic airway epithelium
10.1038/nmat4357 · 2015 · External reference
EMT transition states during tumor progression and metastasis
10.1016/j.tcb.2018.12.001 · 2019 · External reference
Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
10.1083/jcb.202003063 · 2020 · External reference
Cellular motility driven by assembly and disassembly of actin filaments
10.1016/s0092-8674(03)00120-x · 2003 · External reference
Collagen reorganization at the tumor-stromal interface facilitates local invasion
10.1186/1741-7015-4-38 · 2006 · External reference
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
10.1126/science.aad7611 · 2016 · External reference
Contribution of integrin adhesion to cytokinetic abscission and genomic integrity
10.3389/fcell.2022.1048717 · 2022 · External reference
Rho GTPases and cell migration
10.1242/jcs.114.15.2713 · 2001 · External reference
The small GTP-Binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
10.1016/0092-8674(92)90163-7 · 1992 · External reference
Systematic review and meta-analysis of the impact of tumour budding in colorectal cancer
10.1038/bjc.2016.274 · 2016 · External reference
Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer
10.1093/jnci/dju136 · 2014 · External reference
Control of MT1-MMP transport by atypical PKC during breast-cancer progression
10.1073/pnas.1400749111 · 2014 · External reference
The structural basis of actin filament branching by the Arp2/3 complex
10.1083/jcb.200709092 · 2008 · External reference
Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
10.1172/jci45817 · 2012 · External reference
Rac activation and inactivation control plasticity of tumor cell movement
10.1016/j.cell.2008.09.043 · 2008 · External reference
ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma
10.1016/j.ccr.2011.06.018 · 2011 · External reference
Topological defects in epithelia govern cell death and extrusion
10.1038/nature21718 · 2017 · External reference
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling
10.1073/pnas.1107807108 · 2011 · External reference
Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas
10.1126/science.1248627 · 2014 · External reference
The involvement of the chromosome 11q13 region in human malignancies: cyclin D1 and EMS1 are two new candidate oncogenes-a review
10.1016/0378-1119(94)00562-7 · 1995 · External reference
Isoform-specific contributions of α-actinin to glioma cell mechanobiology
10.1371/journal.pone.0008427 · 2009 · External reference
Extracellular signalling modulates Scar/WAVE complex activity through abi phosphorylation
10.3390/cells10123485 · 2021 · External reference
Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells
10.1038/s42003-024-06163-z · 2024 · External reference
The ZEB1/miR-200c feedback loop regulates invasion via actin-interacting proteins MYLK and TKS5
10.18632/oncotarget.4807 · 2015 · External reference
The actin cytoskeleton and actin-based motility
10.1101/cshperspect.a018267 · 2018 · External reference
Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
10.1186/1741-7015-11-52 · 2013 · External reference
Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment
10.1016/j.actbio.2022.04.031 · 2023 · External reference
Physical forces during collective cell migration
10.1038/nphys1269 · 2009 · External reference
Microenvironmental stiffness enhances glioma cell proliferation by stimulating epidermal growth factor receptor signaling
10.1371/journal.pone.0101771 · 2014 · External reference
The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
10.1083/jcb.200510115 · 2006 · External reference
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis
10.1083/jcb.200209006 · 2003 · External reference
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
10.1158/0008-5472.can-04-1449 · 2004 · External reference
Structural basis of CYRI-B direct competition with Scar/WAVE complex for Rac1
10.1016/j.str.2020.11.003 · 2021 · External reference
A duality based approach for realtime TV-L1 optical flow
2007 · External reference
A primer to traction force microscopy
10.1016/j.jbc.2022.101867 · 2022 · External reference
Profilin-1 is a negative regulator of mammary carcinoma aggressiveness
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