Research graph
References from Lipid droplet–mitochondria contact sites as druggable spatial-pharmacology targets in respiratory disease: cross–cell-type mechanisms and translational strategies. Local targets link to admitted publications; unresolved targets remain external evidence.
New insights into pathomechanisms and treatment possibilities for lung silicosis
10.3390/ijms22084162 · 2021 · External reference
Foam cell macrophages in tuberculosis
10.3389/fimmu.2021.775326 · 2021 · External reference
Alveolar lipids in pulmonary disease. A review
10.1186/s12944-020-01278-8 · 2020 · External reference
Liposomes or extracellular vesicles: a comprehensive comparison of both lipid bilayer vesicles for pulmonary drug delivery
10.3390/polym15020318 · 2023 · External reference
Excess iron promotes emergence of foamy macrophages that overexpress ferritin in the lungs of silicosis patients
10.1111/resp.14230 · 2022 · External reference
Regulation of lung progenitor plasticity and repair by fatty acid oxidation
10.1172/jci.insight.165837 · 2025 · External reference
Alveolar lipid-macrophage networks at the intersection of pulmonary fibrosis
10.3390/cells15080668 · 2026 · External reference
Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge
10.1126/sciadv.abn7162 · 2022 · External reference
Optimized inhaled LNP formulation for enhanced treatment of idiopathic pulmonary fibrosis via mRNA-mediated antibody therapy
10.1038/s41467-024-51056-8 · 2024 · External reference
Mitochondria bound to lipid droplets have unique bioenergetics, composition, and dynamics that support lipid droplet expansion
10.1016/j.cmet.2018.03.003 · 2018 · External reference
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites
10.1038/s41467-025-57405-5 · 2025 · External reference
Current and future treatment landscape for idiopathic pulmonary fibrosis
10.1007/s40265-023-01950-0 · 2023 · External reference
Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD
10.1016/j.metabol.2023.155765 · 2024 · External reference
Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis
10.1016/j.redox.2020.101509 · 2020 · External reference
Construction of a novel lipid drop-mitochondria-associated genetic profile for predicting the survival and prognosis of lung adenocarcinoma
10.1007/s12672-024-01526-8 · 2024 · External reference
Key challenges and recommendations for defining organelle membrane contact sites
10.1038/s41580-025-00864-x · 2025 · External reference
Lipid-protein and protein-protein interactions in the pulmonary surfactant system and their role in lung homeostasis
10.3390/ijms21103708 · 2020 · External reference
Rodent models of lung disease: a road map for translational research
10.3390/ijms26178386 · 2025 · External reference
Ferroptosis and mitochondrial ROS are central to SARS-CoV-2-induced hepatocyte death
10.3389/fcimb.2025.1625928 · 2025 · External reference
HUB genes transcriptionally regulate lipid metabolism in alveolar type II cells under LPS stimulation
10.1016/j.heliyon.2023.e19437 · External reference
Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
10.1038/s41392-023-01510-8 · External reference
The impact of mycobacterium tuberculosis on the macrophage cholesterol metabolism pathway
10.3389/fimmu.2024.1402024 · 2024 · External reference
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis
10.1038/s41467-019-11327-1 · 2019 · External reference
Mitochondrial dysfunction in lung ageing and disease
10.1183/16000617.0165-2020 · 2020 · External reference
Two types of contact between lipid droplets and mitochondria
10.3389/fcell.2020.618322 · 2020 · External reference
Transplantation of mesenchymal stromal cell-derived mitochondria alleviates endothelial dysfunction in pre-clinical models of acute respiratory distress syndrome
10.1093/stcltm/szaf053 · 2025 · External reference
The role of mitochondrial fat oxidation in cancer cell proliferation and survival
10.3390/cells9122600 · 2020 · External reference
Engineering lipid nanoparticles to enhance intracellular delivery of transforming growth factor-beta siRNA (siTGF-β1) via inhalation for improving pulmonary fibrosis post-bleomycin challenge
10.3390/pharmaceutics17020157 · 2025 · External reference
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators
10.1371/journal.ppat.1009127 · 2020 · External reference
Channels and transporters of the pulmonary lamellar body in health and disease
10.3390/cells11010045 · 2021 · External reference
Mitochondrial extracellular vesicles: a promising avenue for diagnosing and treating lung diseases
10.1021/acsnano.4c02940 · 2024 · External reference
A guide to characterizing the dynamic mitochondria-endoplasmic reticulum contact sites
10.1111/febs.70184 · 2025 · External reference
CD44 loss disrupts lung lipid surfactant homeostasis and exacerbates oxidized lipid-induced lung inflammation
10.3389/fimmu.2020.00029 · 2020 · External reference
Lipid metabolism modulation during SARS-CoV-2 infection: a spotlight on extracellular vesicles and therapeutic prospects
10.3390/ijms25010640 · 2024 · External reference
Reprogramming of lipid metabolism in lung cancer: an overview with focus on EGFR-mutated non-small cell lung cancer
10.3390/cells11030413 · 2022 · External reference
Functional interplay of lipid droplets and mitochondria
10.1002/1873-3468.14809 · 2024 · External reference
Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling
10.1183/13993003.04252-2020 · 2021 · External reference
Mitochondria-targeted antioxidants as a therapeutic strategy for chronic obstructive pulmonary disease
10.3390/antiox12040973 · 2023 · External reference
Engineering of pulmonary surfactant corona on inhaled nanoparticles to operate in the lung system
10.1016/j.nantod.2023.101998 · 2023 · External reference
Lipid droplet-mitochondria contacts in health and disease
10.3390/ijms25136878 · 2024 · External reference
Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPD
10.1172/jci.insight.163403 · 2023 · External reference
Single cell transcriptomics identifies distinct profiles in pediatric acute respiratory distress syndrome
10.1038/s41467-023-39593-0 · 2023 · External reference
Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis
10.1038/s41588-024-01819-2 · 2024 · External reference
MIGA2 links mitochondria, the ER, and lipid droplets and promotes de novo lipogenesis in adipocytes
10.1016/j.molcel.2019.09.011 · 2019 · External reference
Multisociety consensus quality improvement revised consensus statement for endovascular therapy of acute ischemic stroke
10.1177/1747493018778713 · 2018 · External reference
Fatty acid metabolism and idiopathic pulmonary fibrosis
10.3389/fphys.2021.794629 · 2021 · External reference
Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but mycobacterium tuberculosis counteracts this process via HIF-1α activation
10.1371/journal.ppat.1008929 · 2020 · External reference
Cholesterol-mediated inflammation activation in alveolar macrophages
10.1186/s12915-025-02494-3 · 2025 · External reference
Impact of nebulization on the physicochemical properties of polymer-lipid hybrid nanoparticles for pulmonary drug delivery
10.3390/ijms25095028 · 2024 · External reference
Molecular mechanisms of perilipin protein function in lipid droplet metabolism
10.1002/1873-3468.14792 · 2024 · External reference
Lung adenocarcinoma cell sensitivity to chemotherapies: a spotlight on lipid droplets and SREBF1 gene
10.3390/cancers14184454 · 2022 · External reference
Targeting Cpt1a-bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling
10.1038/s41418-021-00840-w · 2022 · External reference
Lipid-laden macrophages as biomarkers of vaping-associated lung injury
10.1016/s2213-2600(19)30476-x · 2020 · External reference
The bronchoalveolar lavage dilution conundrum: an updated view on a long-standing problem
10.1152/ajplung.00054.2024 · 2024 · External reference
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer
10.1038/s41586-023-05793-3 · 2023 · External reference
HPS6 deficiency leads to reduced vacuolar-type H+-ATPase and impaired biogenesis of lamellar bodies in alveolar type II cells
10.1165/rcmb.2022-0492oc · 2024 · External reference
Mitochondrial dysfunction and metabolic reprogramming in obesity and asthma
10.3390/ijms25052944 · 2024 · External reference
Lipid droplet contact sites in health and disease
10.1016/j.tcb.2021.01.004 · 2021 · External reference
Endogenous LXR signaling controls pulmonary surfactant homeostasis and prevents lung inflammation
10.1007/s00018-024-05310-3 · 2024 · External reference
FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism
10.1016/j.celrep.2022.111668 · 2022 · External reference
The effect of short-chain fatty acids on M2 macrophages polarization in vitro and in vivo
10.1093/cei/uxab028 · 2022 · External reference
Implications of lipid droplets in lung cancer: associations with drug resistance
10.3892/ol.2020.11769 · 2020 · External reference
Advancements in nanotechnology for targeted drug delivery in idiopathic pulmonary fibrosis: a focus on solid lipid nanoparticles and nanostructured lipid carriers
10.1080/03639045.2025.2468811 · 2025 · External reference
Tension-induced organelle stress: an emerging target in fibrosis
10.1016/j.tips.2024.12.006 · 2025 · External reference
Identification of host regulators of mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence
10.1016/j.chom.2023.05.009 · 2023 · External reference
High-fat diet obesity exacerbates acute lung injury-induced dysregulation of fatty acid oxidation in alveolar epithelial type 2 cells
10.1152/ajplung.00406.2024 · 2025 · External reference
PLIN5 phosphorylation orchestrates mitochondria lipid-droplet coupling to control hepatic lipid flux and steatosis
10.1038/s42255-026-01476-1 · 2026 · External reference
Precision medicine advances in idiopathic pulmonary fibrosis
10.1016/j.ebiom.2023.104766 · 2023 · External reference
Inhalable gene therapy and the lung surfactant problem
10.1021/acs.nanolett.3c03547 · 2023 · External reference
Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases
10.1136/thorax-2023-221148 · 2024 · External reference
Lipid droplet-mitochondria coupling via perilipin 5 augments respiratory capacity but is dispensable for FA oxidation
10.1016/j.jlr.2022.100172 · 2022 · External reference
Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites
10.1038/s41467-022-31462-6 · 2022 · External reference
Post-correlation on-lamella cryo-CLEM reveals the membrane architecture of lamellar bodies
10.1038/s42003-020-01567-z · 2021 · External reference
Lipid droplet formation in mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense
10.1371/journal.ppat.1006874 · 2018 · External reference
Spatial pharmacology: redefining organelle contact sites as therapeutic targets
10.7150/ijbs.129515 · 2026 · External reference
AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells
10.1073/pnas.2025208118 · 2021 · External reference
Exploring the influence of metabolic changes in fibrotic lung diseases
10.1002/pul2.70163 · 2025 · External reference
Fast and deep phosphoproteome analysis with the orbitrap astral mass spectrometer
10.1038/s41467-024-51274-0 · 2024 · External reference
Mitochondrial quality control in pulmonary fibrosis
10.1016/j.redox.2020.101426 · 2020 · External reference
Not too fat to fight: the emerging role of macrophage fatty acid metabolism in immunity to mycobacterium tuberculosis
10.1111/imr.12952 · 2021 · External reference
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension
10.1152/ajplung.00039.2022 · 2022 · External reference
Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis
10.1016/j.jlr.2024.100496 · External reference
Mitochondrial transplantation attenuates lipopolysaccharide-induced acute respiratory distress syndrome
10.1186/s12890-024-03304-2 · External reference
Prediction of TKI response in EGFR-mutant lung cancer patients-derived organoids using malignant pleural effusion
10.1038/s41698-024-00609-7 · External reference
The role of autophagy in lamellar body formation and surfactant production in type 2 alveolar epithelial cells
10.7150/ijbs.64285 · 2022 · External reference
Inhaled lipid nanoparticles alleviate established pulmonary fibrosis
10.1002/smll.202300545 · External reference
Pulmonary delivery of specialized pro-resolving mediators-based nanotherapeutics attenuates pulmonary fibrosis in preclinical animal models
10.1021/acsnano.2c10388 · External reference
Reprogramming of lipid metabolism by ORF3a-induced microlipophagy enhances biogenesis of SARS-CoV-2 replication organelle
10.1371/journal.ppat.1013676 · External reference
Epithelial-mesenchymal transition in pulmonary fibrosis: molecular mechanisms and emerging therapeutic strategies
10.3389/fmed.2025.1658001 · External reference
Alveolar macrophages: guardians of the alveolar lipid galaxy
10.1097/mol.0000000000000987 · 2025 · External reference
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling
10.1186/s12951-022-01435-4 · 2022 · External reference
An overview: the diversified role of mitochondria in cancer metabolism
10.7150/ijbs.81609 · 2023 · External reference
Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10
10.1002/jmv.29752 · 2024 · External reference
Double braking effects of nanomedicine on mitochondrial permeability transition pore for treating idiopathic pulmonary fibrosis
10.1002/advs.202405406 · 2024 · External reference
Immunometabolic programming of macrophages in asthma pathogenesis and therapy
10.3389/fphys.2025.1736340 · 2025 · External reference
Lipid droplets in lung cancers are crucial for the cell growth and starvation survival
10.3390/ijms232012533 · 2022 · External reference
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer
10.1038/s41392-024-01772-w · 2024 · External reference
Treatment of idiopathic pulmonary fibrosis: an update on emerging drugs in phase II and III clinical trials
10.1080/14728214.2024.2340723 · 2024 · External reference
Cellular stress responses and dysfunctional mitochondrial-cellular senescence, and therapeutics in chronic respiratory diseases
10.1016/j.redox.2020.101443 · 2020 · External reference
Revisiting focused ion beam scanning electron microscopy
10.1016/j.tibs.2023.02.005 · 2023 · External reference
Lipid droplets and cellular lipid flux
10.1038/s41556-024-01364-4 · 2024 · External reference
A framework for translational research in interstitial lung disease (ILD) using bronchoalveolar lavage (BAL)
10.1080/1744666x.2026.2675640 · 2026 · External reference
Biomarkers of mitochondrial dysfunction in acute respiratory distress syndrome: a systematic review and meta-analysis
10.3389/fmed.2022.1011819 · 2022 · External reference
Lipid droplets and the transcriptome of mycobacterium tuberculosis from direct sputa: a literature review
10.1186/s12944-021-01550-5 · 2021 · External reference
Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet-mitochondria tethering to enhance β-oxidation and tumor cell proliferation
10.1038/s42255-024-01047-2 · 2024 · External reference
PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport
10.1016/j.devcel.2023.05.006 · 2023 · External reference
Perilipin 2 mediates progression of lung adenocarcinoma by modulating lipid metabolism
10.1016/j.ajpath.2025.05.016 · 2025 · External reference
Mycobacterial control of host mitochondria: bioenergetic and metabolic changes shaping cell fate and infection outcome
10.3389/fcimb.2020.00457 · 2020 · External reference
Pulmonary surfactant protein SP-C regulates lipid vesicle uptake by alveolar type II cells and macrophages: role of lipids, palmitoylation, and environment
10.1016/j.bbalip.2025.159688 · 2025 · External reference
Advancements in global phosphoproteomics profiling: overcoming challenges in sensitivity and quantification
10.1002/pmic.202400087 · 2025 · External reference
Lipid droplet-derived monounsaturated fatty acids traffic via PLIN5 to allosterically activate SIRT1
10.1016/j.molcel.2019.12.003 · 2020 · External reference
Cellular and molecular control of lipid metabolism in idiopathic pulmonary fibrosis: clinical application of the lysophosphatidic acid pathway
10.3390/cells12040548 · 2023 · External reference
Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis
10.1038/s41419-021-03527-9 · 2021 · External reference
Ferroptosis-immune-metabolic axis in asthma: mechanistic crosstalk, endotype-specific regulation, and translational targeting
10.3389/fimmu.2025.1714608 · 2025 · External reference
Ironing out COPD: Ferroptosis-driven immune dysregulation, metabolic rewiring, and precision therapeutic opportunities
10.3389/fimmu.2026.1630969 · 2026 · External reference
Elamipretide(SS-31) attenuates idiopathic pulmonary fibrosis by inhibiting the Nrf2-dependent NLRP3 inflammasome in macrophages
10.3390/antiox12122022 · 2023 · External reference
Perilipins: key targets for regulating lipid metabolism and alleviating abnormal lipid metabolism through exercise
10.1186/s13098-025-01965-5 · 2025 · External reference
Protein network analyses of pulmonary endothelial cells in chronic thromboembolic pulmonary hypertension
10.1038/s41598-021-85004-z · 2021 · External reference
The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations
10.1038/s41598-018-24676-6 · 2018 · External reference
The mitochondrial nexus: dysfunction, inhibition, and therapeutic frontiers in lung disease
10.1016/j.rmed.2025.108506 · 2025 · External reference
Lipid droplet-mitochondria tethering releases MAVS inhibition to potentiate antiviral immunity
10.1016/j.celrep.2026.117601 · 2026 · External reference
Metabolic reprogramming, oxidative stress, and pulmonary hypertension
10.1016/j.redox.2023.102797 · 2023 · External reference
Mitochondrial network dynamics in pulmonary disease: bridging the gap between inflammation, oxidative stress, and bioenergetics
10.1016/j.redox.2024.103049 · 2024 · External reference
Mechanisms of surfactant maturation in development and disease
10.1152/physiol.00033.2025 · 2026 · External reference
Multi-omics reveals cholesterol-driven macrophage metabolic reprogramming and inflammation in chronic obstructive pulmonary disease
10.1186/s13073-025-01591-w · 2026 · External reference
Metabolic differences between bronchial epithelium from healthy individuals and patients with asthma and the effect of bronchial thermoplasty
10.1016/j.jaci.2020.12.653 · 2021 · External reference
Therapeutic targeting of metabolic alterations in acute respiratory distress syndrome
10.1183/16000617.0114-2020 · 2020 · External reference
Alveolar macrophage metabolic programming via a C-type lectin receptor protects against lipo-toxicity and cell death
10.1038/s41467-022-34935-w · 2022 · External reference
The expanding role of mitochondria-lipid droplet contacts in liver and their disruption by MASLD
10.1038/s42255-026-01483-2 · 2026 · External reference
Mechanism of lamellar body formation by lung surfactant protein B
10.1016/j.molcel.2020.10.042 · 2021 · External reference
Causal relationship between lipidome and acute respiratory distress syndrome
10.1038/s41598-024-80985-z · 2024 · External reference
The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases
10.1186/s12944-024-02062-8 · 2024 · External reference
Augmenting macrophages apoptosis induced by carnitine palmitoyl transferase 1A inhibition via acetyl-coa-associated protein acetylation
10.1111/imm.13917 · 2025 · External reference
Mycobacterium tuberculosis infection-driven foamy macrophages and their implications in tuberculosis control as targets for host-directed therapy
10.3389/fimmu.2020.00910 · 2020 · External reference
The role of interaction between mitochondria and the extracellular matrix in the development of idiopathic pulmonary fibrosis
10.1155/2021/9932442 · 2021 · External reference
Fatty acid trafficking between lipid droplets and mitochondria: an emerging perspective
10.7150/ijbs.105361 · 2025 · External reference
Knockout of perilipin-2 in microglia alters lipid droplet accumulation and response to alzheimer’s disease stimuli
10.3390/cells14221783 · 2025 · External reference
Etiology of lipid-laden macrophages in the lung
10.1016/j.intimp.2023.110719 · 2023 · External reference
Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations
10.1172/jci164274 · 2024 · External reference
Lipid-droplet associated mitochondria promote fatty-acid oxidation through a distinct bioenergetic pattern in male wistar rats
10.1038/s41467-023-36432-0 · 2023 · External reference
Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: a review
10.1016/j.biocel.2022.106361 · 2023 · External reference
Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapy
10.1038/s41389-022-00400-y · 2022 · External reference
Inhaled nano-based therapeutics for pulmonary fibrosis: recent advances and future prospects
10.1186/s12951-023-01971-7 · 2023 · External reference
The role of perilipin 2 in pseudomonas aeruginosa pulmonary infection
10.1016/j.resp.2020.103497 · 2020 · External reference
Genetic variety of ORF3a shapes SARS-CoV-2 fitness through modulation of lipid droplet
10.1002/jmv.28630 · 2023 · External reference
Realveolarization with inhalable mucus-penetrating lipid nanoparticles for the treatment of pulmonary fibrosis in mice
10.1126/sciadv.ado4791 · External reference
CPT1A as a potential therapeutic target for lipopolysaccharide-induced acute lung injury in mice
10.1038/s41598-024-52042-2 · External reference
Mitophagy-enhanced nanoparticle-engineered mitochondria restore homeostasis of mitochondrial pool for alleviating pulmonary fibrosis
10.1021/acsnano.4c10328 · External reference
CPT1A-IL-10-mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury
10.1002/ctm2.1785 · External reference
Interactions between lipid droplets and mitochondria in metabolic diseases
10.1186/s12944-025-02759-4 · External reference
MSC-mediated mitochondrial transfer promotes metabolic reprograming in endothelial cells and vascular regeneration in ARDS
10.1080/13510002.2025.2474897 · External reference
Oxidative stress in ARDS: mechanisms and therapeutic potential
10.3389/fphar.2025.1603287 · External reference
Protective role of fatty acid oxidation against epithelial barrier dysfunction in allergic asthma
10.1080/13510002.2026.2613534 · 2026 · External reference
AKR1C3-dependent lipid droplet formation confers hepatocellular carcinoma cell adaptability to targeted therapy
10.7150/thno.74974 · 2022 · External reference
SREBP2 promotes macrophage alternative activation and allergic airway inflammation independent of cholesterol biosynthesis
10.1038/s41419-026-08910-y · 2026 · External reference
Macrophage immunometabolism in pulmonary homeostasis and chronic lung diseases
10.7150/ijbs.123492 · 2025 · External reference
GCN5L1 regulates pulmonary surfactant production by modulating lamellar body biogenesis and trafficking in mouse alveolar epithelial cells
10.1186/s11658-023-00506-0 · 2023 · External reference
MiR-365-3p inhibits lung cancer proliferation and migration via CPT1A-mediated fatty acid oxidation
10.1038/s41598-025-91665-x · 2025 · External reference
Downregulation of HMGCS2 mediated AECIIs lipid metabolic alteration promotes pulmonary fibrosis by activating fibroblasts
10.1186/s12931-024-02816-z · 2024 · External reference
The role of PLIN3 in prognosis and tumor-associated macrophage infiltration: a pan-cancer analysis
10.2147/jir.s509245 · 2025 · External reference
Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation
10.1371/journal.pbio.2003782 · 2018 · External reference
DPEP1 mediates regulation of mitochondrial quality control via FOXO1/ALDH1L2 axis to attenuate ferroptosis in pulmonary endothelial cells to alleviate sepsis-associated acute lung injury
10.1016/j.intimp.2025.116049 · 2026 · External reference
Lipid droplet biogenesis and functions in health and disease
10.1038/s41574-023-00845-0 · 2023 · External reference
Mechanisms of alveolar type II epithelial cells’ mitochondrial quality control during acute lung injury/acute respiratory distress syndrome: bridging the gap between oxidative stress, inflammation, and fibrosis
10.3389/fphys.2025.1684729 · 2025 · External reference
A phase-2 NIH-sponsored randomized clinical trial of rituximab in scleroderma-associated pulmonary arterial hypertension did not reach significance for its endpoints: end of story? Not so fast
10.1164/rccm.202103-0612ed · 2021 · External reference
Plin5 bidirectionally regulates lipid metabolism in oxidative tissues
10.1155/2022/4594956 · 2022 · External reference
Molecular mechanisms of lipid droplets-mitochondria coupling in obesity and metabolic syndrome: insights and pharmacological implications
10.3389/fphys.2024.1491815 · 2024 · External reference
Mitochondrial pathway signature (MitoPS) predicts immunotherapy response and reveals NDUFB10 as a key immune regulator in lung adenocarcinoma
10.1136/jitc-2025-012069 · 2025 · External reference
Lipid-laden macrophages in pulmonary diseases
10.3390/cells13110889 · External reference
Acod1/itaconate activates Nrf2 in pulmonary microvascular endothelial cells to protect against the obesity-induced pulmonary microvascular endotheliopathy
10.1186/s12931-024-02827-w · External reference
Landscape expansion microscopy reveals interactions between membrane and phase-separated organelles
10.1083/jcb.202502035 · 2026 · External reference
Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery
10.1016/j.jconrel.2022.09.021 · 2022 · External reference
Mitochondrial dysfunction: mechanisms and advances in therapy
10.1038/s41392-024-01839-8 · 2024 · External reference
