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References from Antitumor and proliferative modulation by N- and O-heterocycles: a comprehensive review of cell growth regulation. Local targets link to admitted publications; unresolved targets remain external evidence.
Synthesis, characterization and biological research of novel 2-(quinoline-4-carbonyl)hydrazide-acrylamide hybrids as potential anticancer agents
10.1039/d4ra03963g · 2024 · External reference
Synthesis and evaluation of new benzimidazole derivatives with hydrazone moiety as anticancer agents
10.1515/tjb-2017-0167 · 2018 · External reference
Synthesis and biological evaluation of hydrazide-hydrazone derivatives
10.17344/acsi.2022.7614 · 2022 · External reference
Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development
10.1016/j.bioorg.2017.01.011 · 2017 · External reference
Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based on 4H-benzo[h]chromene
10.1016/j.bioorg.2019.03.059 · 2019 · External reference
Synthesis, characterization, and cytotoxicity of new spirooxindoles
10.1021/acsomega.2c03790 · 2022 · External reference
Synthesis, antitumor activity evaluation, and DNA-binding study of coumarin-based agents
10.1002/ardp.201700199 · 2018 · External reference
Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents
10.1016/j.ejmech.2013.03.008 · 2013 · External reference
Coumarins and gastrointestinal cancer: a new therapeutic option
10.3389/fonc.2021.752784 · 2021 · External reference
Design and synthesis of some novel hydrazide, 1,2-dihydropyridine, chromene derivatives carrying biologically active sulfone moieties with potential anticancer activity
10.1055/s-0031-1296238 · 2011 · External reference
Synthesis of hydrazides of heterocyclic amines and their antimicrobial and spasmolytic activity
10.1016/j.jsps.2022.04.009 · 2022 · External reference
Synthesis, characterization and anti-cancer activity of hydrazide derivatives incorporating a quinoline moiety
10.3390/molecules21070916 · 2016 · External reference
Design and synthesis of new furan-based derivatives and evaluation of in vitro cytotoxic activity
10.3390/molecules27082606 · 2022 · External reference
Development of novel bis(indolyl)-hydrazide-hydrazone derivatives as microtubule-targeting cytotoxic agents
10.1021/acs.biochem.5b01127 · 2016 · External reference
Indole derivatives as multifunctional drugs
10.1016/j.bioorg.2019.02.007 · 2019 · External reference
Thiosemicarbazides of piperidylacetic acid in the synthesis of bisheterocyclic compounds
10.1134/s107036321507035x · 2015 · External reference
Antimicrobial activity of 1,2,5-trimethylpiperidin-4-ol derivatives
10.1007/s11094-017-1652-x · 2017 · External reference
Studies on the synthesis and in vitro antitumor activity of benzochromene derivatives
10.1007/s00044-013-0904-x · 2014 · External reference
In vitro anticancer activity of pyrano[3,2-c]chromene derivatives with both cell cycle arrest and apoptosis induction
10.1007/s00044-019-02494-3 · 2020 · External reference
Targeted potent antimicrobial and antitumor oxygen-heterocyclic-based pyran analogues
10.1038/s41598-024-59193-2 · 2024 · External reference
Synthesis and in vitro anticancer activity of some novel tetrahydroquinoline derivatives bearing pyrazol and hydrazide moiety
10.1002/jhet.3930 · 2020 · External reference
Synthesis and anticancer activity of 6-heteroarylcoumarins
10.1016/j.ejmech.2015.10.021 · 2015 · External reference
Synthesis and antitumor activity of some novel hydrazide, 1,2-dihydropyridine, chromene, and benzochromene derivatives
10.1002/jhet.829 · 2012 · External reference
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents
10.1517/13543780902858815 · 2009 · External reference
Design, synthesis, and antiproliferative activity of benzopyran-4-one-isoxazole hybrids
10.3390/molecules28104220 · 2023 · External reference
Anticancer activity of anti-tubercular compound(s) designed on pyrrolyl benzohydrazine scaffolds: a repurposing study
10.3390/pr11071889 · 2023 · External reference
Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4-triazole containing hydrazide-hydrazones derived from (S)-naproxen
10.1002/ardp.201800365 · 2019 · External reference
Synthesis and docking studies of novel benzopyran-2-ones with anticancer activity
10.1016/j.ejmech.2010.05.050 · 2010 · External reference
Novel indole hydrazide derivatives: synthesis and antiproliferative activities
10.1002/ardp.202000059 · 2020 · External reference
Synthesis, structure, chemical stability, and in vitro cytotoxic properties of novel quinoline-3-carbaldehyde hydrazones
10.3390/molecules23061497 · 2018 · External reference
Novel bis(indolyl)hydrazide-hydrazones as potent cytotoxic agents
10.1016/j.bmcl.2011.11.031 · 2012 · External reference
4-aryl/heteroaryl-4H-fused pyrans as anti-proliferative agents
10.2174/1871520617666170918143911 · 2018 · External reference
Nitrogen containing heterocycles as anticancer agents: a medicinal chemistry perspective
10.3390/ph16020299 · 2023 · External reference
Synthesis and antitumor evaluation of novel tetrahydrobenzo[4′,5′]thieno[3′,2′:5,6]pyrimido[1,2-b]isoquinoline derivatives
10.1080/00397911.2017.1406520 · 2018 · External reference
Quinolines and oxazino-quinoline derivatives as small molecule GLI1 inhibitors identified by virtual screening
10.1021/acsmedchemlett.2c00249 · 2022 · External reference
Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth
10.1016/j.phrs.2023.106858 · 2023 · External reference
Synthesis and study of anticancer and antioxidant activities of 2-oxoquinoline hydrazide derivatives
10.7454/mss.v27i1.1495 · 2023 · External reference
Synthesis of novel hydrazone and azole functionalized pyrazolo[3,4-b]pyridine derivatives as promising anticancer agents
10.1016/j.bmcl.2016.08.006 · 2016 · External reference
Anticancer activity of new coumarin substituted hydrazide-hydrazone derivatives
10.1016/j.ejmech.2014.02.026 · 2014 · External reference
Synthesis and evaluation of anticancer activity of 2-arylamino-6-trifluoromethyl-3-(hydrazonocarbonyl)pyridines
10.1016/j.bmc.2009.07.066 · 2009 · External reference
Design and synthesis of highly oxygenated furo[3,2-c]pyran4-ones and furo[3,2-c]chromen-4-ones scaffold as anticancer and antimicrobial agents
10.1002/jhet.4374 · 2022 · External reference
Synthesis and cytotoxicity activity of some novel hydrazide, pyrazole, isoxazole, pyrimidine and fused pyran-2-one derivatives
10.3987/com-15-13209 · 2015 · External reference
Discovery of potent indolyl-hydrazones as kinase inhibitors for breast cancer
10.3390/ph16121724 · 2023 · External reference
Novel synthesis of pyran-3-hydrazide derivatives and their uses to the synthesis hydrazide-hydrazone, pyrazole and thiazole derivatives with anticancer activities
10.4314/bcse.v35i3.9 · 2022 · External reference
Discovery of hydrazide-based pyridazino[4,5-b]indole scaffold as a new phosphoinositide 3-kinase (PI3K) inhibitor for breast cancer therapy
10.1039/d0ra02798g · 2020 · External reference
Identification of new indole carbohydrazide derivatives as tubulin inhibitors
10.1016/j.bioorg.2021.104795 · 2021 · External reference
Novel 2,6-disubstituted pyridine hydrazones: synthesis, anticancer activity, docking studies and effects on caspase-3-mediated apoptosis
10.1016/j.molstruc.2020.128962 · 2021 · External reference
Recent perspectives on anticancer potential of coumarin against different human malignancies: an updated review
10.1002/fsn3.4696 · 2024 · External reference
Anti-breast cancer activity of heteroaryl chalcone derivatives
10.1016/j.biopha.2011.11.013 · 2012 · External reference
Synthesis and antitumor evaluation of indole–indazolyl hydrazide–hydrazone derivatives
10.1007/s00706-016-1750-6 · 2017 · External reference
Synthesis and anticancer activity study of indolyl hydrazide–hydrazones
10.1007/s00044-016-1522-1 · 2016 · External reference
Morpholine hydrazone scaffold: synthesis, anticancer activity and docking studies
10.1016/j.cclet.2016.10.020 · 2017 · External reference
Synthesis, cytotoxicity and antiproliferative effect of new pyrrole hydrazones
10.3390/molecules29235499 · 2024 · External reference
Antiproliferative and pro-apoptotic activity and tubulin dynamics modulation of 1H-benzimidazol-2-yl hydrazones in human breast cancer cell line MDA-MB-231
10.3390/molecules29102400 · 2024 · External reference
Synthesis and biological evaluation of 1,3,8-triazaspiro[4.5]decane-2,4-dione derivatives as myelostimulators
10.1155/2018/7346835 · 2018 · External reference
Naphthaleneoxypropargyl-containing piperazine as a regulator of effector immune cell populations upon an aseptic inflammation
10.3390/molecules28207023 · 2023 · External reference
Targeted restoration of T-cell subsets by a fluorinated piperazine derivative β-cyclodextrin complex in experimental pulmonary inflammation
10.3390/molecules30132741 · 2025 · External reference
Synthesis and anticancer properties of novel hydrazone derivatives incorporating pyridine and isatin moieties
10.1002/ardp.202000377 · 2021 · External reference