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References from Codonopsis pilosula polysaccharides: structural characteristics, structure–activity relationships, biological activities, and potential applications. Local targets link to admitted publications; unresolved targets remain external evidence.
Cytotoxicity of two water-soluble polysaccharides from Codonopsis pilosula Nannf. var. modesta (Nannf.) L.T.Shen against human hepatocellular carcinoma HepG2 cells and its mechanism
10.1016/j.ijbiomac.2018.09.123 · 2018 · External reference
Codonopsis Radix: a comprehensive review for its ethnopharmacology, phytochemistry, pharmacodynamics, pharmacokinetics, toxicity and potential clinical applications
10.1016/j.phymed.2025.157540 · 2025 · External reference
The mechanism of Codonopsis pilosula in treating chronic obstructive pulmonary disease via exploring network pharmacology and multi-omics
10.1016/j.jep.2025.121082 · 2026 · External reference
Separation, purification, structure analysis, in vitro antioxidant activity and circRNA-miRNA-mRNA regulatory network on PRV-Infected RAW264.7 cells of a polysaccharide derived from Arthrospira platensis
10.3390/antiox10111689 · 2021 · External reference
Carboxymethylation of polysaccharides: synthesis and bioactivities
10.1016/j.ijbiomac.2020.10.178 · 2020 · External reference
Polysaccharides from traditional Chinese medicines: extraction, purification, modification, and biological activity
10.3390/molecules21121705 · 2016 · External reference
Size-dependent whitening activity of enzyme-degraded fucoidan from Laminaria japonica
10.1016/j.carbpol.2019.115211 · 2019 · External reference
Structure-immunomodulatory activity relationships of dietary polysaccharides
10.1016/j.crfs.2022.08.016 · 2022 · External reference
Preparation, structural characterization, biological activity, and nutritional applications of oligosaccharides
10.1016/j.fochx.2024.101289 · 2024 · External reference
Codonopsis pilosula polysaccharides attenuate lipid accumulation and inflammatory response in the NAFLD mouse by regulating AMPK/ACC/SREBP1 signaling pathway
10.1016/j.tice.2025.102984 · 2025 · External reference
Structural characterization and hepatoprotective activity of a galactoglucan from Poria cocos
10.1016/j.carbpol.2021.117979 · 2021 · External reference
Recent bioanalytical methods for the isolation of bioactive natural products from genus Codonopsis
10.1002/pca.3253 · 2023 · External reference
Oral targeted delivery of codonopsis Radix polysaccharide via succinyl -DHA functionalized nanoparticles efficiently alleviates ulcerative colitis
10.2147/ijn.s484575 · 2024 · External reference
Structural characterization and immunomodulatory activity of fructan polysaccharides from two varieties of codonopsis pilosulae C. pilosula nannf. var. modesta and C. pilosula (Franch.) Nannf
10.3390/foods15030495 · 2026 · External reference
Regulatory effects of Codonopsis pilosula alkali-extracted polysaccharide induced intestinal lactobacillus enrichment on peripheral blood proteomics in tumor-bearing mice
10.3390/microorganisms13081750 · 2025 · External reference
Codonopsis pilosula polysaccharides exert antiviral effect through activating immune function in a macrophage model of Bovine viral diarrhea virus infection
10.3390/vetsci12050415 · 2025 · External reference
Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
10.1016/j.phytochem.2014.10.011 · 2015 · External reference
Effect of polysaccharides from Radix codonopsis on insulin resistance in diabetic mice
2008 · External reference
The polysaccharides from Codonopsis pilosula modulates the immunity and intestinal microbiota of cyclophosphamide-treated immunosuppressed mice
10.3390/molecules23071801 · 2018 · External reference
The structure characterization of polysaccharides from Codonopsis Pilosula and the structure-activity relationship with immune-regulation on THP-1 cells
10.1002/cbdv.202401167 · 2025 · External reference
Ultrasonic degradation of Dendrobium officinale polysaccharide: Kinetics, structural modification, and its impact on wheat starch digestibility
10.1016/j.foodres.2026.118776 · 2026 · External reference
Exploring on the bioactive markers of Codonopsis Radix by correlation analysis between chemical constituents and pharmacological effects
10.1016/j.jep.2019.02.032 · 2019 · External reference
The structural characterization and immune modulation activitives comparison of Codonopsis pilosula polysaccharide (CPPS) and selenizing CPPS (sCPPS) on mouse in vitro and vivo
10.1016/j.ijbiomac.2020.05.149 · 2020 · External reference
Specific inulin in Codonopsis pilosula exerts immunological enhancement by promoting cellular uptake and regulating p65-Dependent MAPK and NF-κb pathways
10.1021/acs.jafc.5c05401 · 2025 · External reference
Changes of physicochemical properties and immunomodulatory activity of polysaccharides during processing of Polygonum multiflorum thunb
10.3389/fphar.2022.934710 · 2022 · External reference
Ultrasound effects on the degradation kinetics, structure, and antioxidant activity of sea cucumber fucoidan
10.1021/jf404717y · 2014 · External reference
β-1,3-glucans from Euglena Gracilis protects against ulcerative colitis via modulating the gut barrier, T-cell immunity and gut microbiota
10.1016/j.ijbiomac.2025.141288 · 2025 · External reference
Codonopsis pilosula polysaccharides alleviate Aβ (1-40)-Induced PC12 cells energy dysmetabolism via CD38/NAD+ signaling pathway
10.2174/1567205018666210608103831 · 2021 · External reference
Uniform and disperse selenium nanoparticles stabilized by inulin fructans from Codonopsis pilosula and their anti-hepatoma activities
10.1016/j.ijbiomac.2022.01.140 · 2022 · External reference
Carboxymethylated Abrus cantoniensis polysaccharide prevents CTX-induced immunosuppression and intestinal damage by regulating intestinal flora and butyric acid content
10.1016/j.ijbiomac.2024.129590 · 2024 · External reference
Codonopsis pilosula polysaccharide suppresses the progression of non-small cell lung cancer by triggering NLRP3/GSDMD-dependent pyroptosis
10.1007/s12672-024-01361-x · 2024 · External reference
Ultrasonic-Assisted extraction of Codonopsis pilosula glucofructan: optimization, structure, and immunoregulatory activity
10.3390/nu14050927 · 2022 · External reference
Hypoglycemic activity of Codonopsis pilosula (Franch.) Nannf. in vitro and in vivo and its chemical composition identification by UPLC-Triple-TOF-MS/MS
10.1039/d1fo03761g · 2022 · External reference
Biological function of Codonopsis pilosula polysaccharide and its application in animal husbandry production
10.3969/j.issn.1006-267x.2021.05.013 · 2021 · External reference
Protective effect of a polysaccharide from stem of Codonopsis pilosula against renal ischemia/reperfusion injury in rats
10.1016/j.carbpol.2012.07.062 · 2012 · External reference
Structure features and anti-gastric ulcer effects of inulin-type fructan CP-A from the roots of Codonopsis pilosula (Franch.) nannf
10.3390/molecules22122258 · 2017 · External reference
Structural characterization and immune activity screening of polysaccharides with different molecular weights from Astragali Radix
10.3389/fphar.2020.582091 · 2020 · External reference
Screening of codonopsis radix polysaccharides with different molecular weights and evaluation of their immunomodulatory activity in vitro and in vivo
10.3390/molecules27175454 · External reference
Structural features and antioxidant activities of polysaccharides from different parts of Codonopsis pilosula var. modesta (Nannf.) L. T. Shen
10.3389/fphar.2022.937581 · External reference
Isolation, purification, and structural characterization of polysaccharides from Codonopsis pilosula and their anti-tumor bioactivity by immunomodulation
10.3390/ph16060895 · 2023 · External reference
Codonopsis radix: a review of resource utilisation, postharvest processing, quality assessment, and its polysaccharide composition
10.3389/fphar.2024.1366556 · 2024 · External reference
The comparison of antioxidative and hepatoprotective activities of Codonopsis pilosula polysaccharide (CP) and sulfated CP
10.1016/j.intimp.2014.12.023 · External reference
Solomonseal polysaccharide and sulfated Codonopsis pilosula polysaccharide synergistically resist Newcastle disease virus
10.1371/journal.pone.0117916 · External reference
Codonopsis lanceolata polysaccharide CLPS inhibits melanoma metastasis via regulating integrin signaling
10.1016/j.ijbiomac.2017.05.093 · 2017 · External reference
Characterization and hypoglycemic effect of a neutral polysaccharide extracted from the residue of Codonopsis Pilosula
10.1016/j.carbpol.2018.05.067 · 2018 · External reference
Codonopsis pilosula polysaccharide in synergy with dacarbazine inhibits mouse melanoma by repolarizing M2-like tumor-associated macrophages into M1-like tumor-associated macrophages
10.1016/j.biopha.2021.112016 · 2021 · External reference
Structural characterization, antioxidant activity, and the effects of Codonopsis pilosula polysaccharides on the solubility and stability of flavonoids
10.1016/j.jpba.2023.115368 · External reference
Antioxidant and DNA protecting activity of carboxymethylated polysaccharides from Cortex periplocae
10.1016/j.ijbiomac.2023.124860 · External reference
Carboxymethyl polysaccharides from Poria cocos (Schw.) wolf: structure, immunomodulatory, anti-inflammatory, tumor cell proliferation inhibition and antioxidant activity
10.1016/j.ijbiomac.2025.140104 · External reference
Effects of selenylation on Chinese yam polysaccharides: structure, antioxidant, and digestive properties
10.1016/j.fochx.2025.102435 · External reference
Polysaccharides with antioxidant activity: extraction, beneficial roles, biological mechanisms, structure-function relationships, and future perspectives: a review
10.1016/j.ijbiomac.2025.140221 · External reference
Immunoregulatory effects of Codonopsis pilosula polysaccharide modified selenium nanoparticles on H22 tumor-bearing mice
10.3390/foods13244073 · 2024 · External reference
Extraction, structural characterization, and biological activities of a new glucan from Codonopsis pilosula
10.1038/s41598-023-31660-2 · 2023 · External reference
Extraction, purification, structural characteristics and biological properties of the polysaccharides from Codonopsis pilosula: a review
10.1016/j.carbpol.2021.117863 · 2021 · External reference
Isolation, purification, and structural characterization of polysaccharides from Codonopsis pilosula and its therapeutic effects on non-alcoholic fatty liver disease in vitro and in vivo
10.1016/j.ijbiomac.2024.130988 · 2024 · External reference
Extraction, characterization and anti-inflammatory activities of an inulin-type fructan from Codonopsis pilosula
10.1016/j.ijbiomac.2020.09.117 · 2020 · External reference
A polysaccharide from Codonopsis pilosula roots attenuates carbon tetrachloride-induced liver fibrosis via modulation of TLR4/NF-κB and TGF-β1/Smad3 signaling pathway
10.1016/j.intimp.2023.110180 · 2023 · External reference
Phosphorylated Codonopsis pilosula polysaccharide could inhibit the virulence of duck hepatitis A virus compared with Codonopsis pilosula polysaccharide
10.1016/j.ijbiomac.2016.10.002 · 2017 · External reference
Unresolved reference
2026 · External reference
Unresolved reference
External reference
Preparation, structural characteristics and immune regulatory effects of Codonopsis pilosula polysaccharides: a review
10.3389/fimmu.2025.1641928 · 2025 · External reference
Effects of selenizing Codonopsis pilosula polysaccharide on macrophage modulatory activities
10.4014/jmb.1601.01094 · 2016 · External reference
Composites of yeast glucan particles and curcumin lead to improvement of dextran sulfate sodium-induced acute bowel inflammation in rats
10.1016/j.carbpol.2020.117142 · 2021 · External reference
Research status and trends of codonopsis radix based on VOSviewer and citespace visual graph
10.13748/j.cnki.issn1007-7693.20224247 · 2023 · External reference
Bioactivities, isolation and purification methods of polysaccharides from natural products: a review
10.1016/j.ijbiomac.2016.06.100 · 2016 · External reference
Characterization and antioxidant activities of degraded polysaccharides from two marine Chrysophyta
10.1016/j.foodchem.2014.03.067 · 2014 · External reference
Structural characterization of three polysaccharides from the roots of Codonopsis pilosula and their immunomodulatory effects on RAW264.7 macrophages
10.1016/j.ijbiomac.2019.02.165 · 2019 · External reference
Preparation, characterization and immune activity of Codonopsis pilosula polysaccharide loaded in chitosan-graphene oxide
10.1016/j.ijbiomac.2022.08.209 · 2022 · External reference
Mannose-B from Codonopsis pilosula modulates LAMB1 expression to enhance trophoblast function and alleviate subchorionic hematoma
10.1038/s41598-025-13918-z · 2025 · External reference
Targeted isolation and identification of bioactive pyrrolidine alkaloids from Codonopsis pilosula using characteristic fragmentation-assisted mass spectral networking
10.1016/s1875-5364(22)60216-4 · External reference
Influence of processing factors on honey-fried Codonopsis Radix
10.19540/j.cnki.cjcmm.20211119.302 · External reference
Sulfated Pelvetia siliquosa polysaccharides attenuate pyroptosis via NF-κB pathway inhibition Against calcium oxalate stone Formation
10.3390/md24020072 · 2026 · External reference
Research progress of processing in production place and processing of codonopsis Radix
10.13422/j.cnki.syfjx.20181601 · 2018 · External reference
Evaluation of the effect of ultrasonic pretreatment on the drying kinetics and quality characteristics of Codonopsis pilosula slices based on the grey correlation method
10.3390/molecules28145596 · 2023 · External reference
Structural characterization and bioactivity analysis of ultrasound-assisted polysaccharides From codonopsis pilosula: insights into antioxidant and hypoglycemic potentials
10.1002/cbdv.202500565 · 2025 · External reference
Temporal and geographic trends in mortality involving co-occurring depression and diabetes mellitus in U. S., 1999-2023
10.3389/fmed.2026.1734188 · External reference
Codonopsis pilosula polysaccharides in intestinal flora and intestinal homeostasis: a review
10.1016/j.ijbiomac.2025.150034 · External reference
Seeing the unseen of Chinese herbal medicine processing (Paozhi): advances in new perspectives
10.1186/s13020-018-0163-3 · 2018 · External reference
Purification, structural characterization, and antioxidant activity of the COP-W1 polysaccharide from Codonopsis tangshen Oliv
10.1016/j.carbpol.2020.116020 · 2020 · External reference
Physicochemical and biological properties of polysaccharides from Dictyophora indusiata prepared by different extraction techniques
10.3390/polym13142357 · 2021 · External reference
Antifatigue and antihypoxia activities of oligosaccharides and polysaccharides from Codonopsis pilosula in mice
10.1039/d0fo00468e · 2020 · External reference
An inulin-type fructan from Codonopsis pilosula ameliorates cyclophosphamide-induced immunosuppression and intestinal barrier injury in mice
10.1016/j.ijbiomac.2025.143312 · 2025 · External reference
The inhibitory effect of a polysaccharide from Codonopsis pilosula on tumor growth and metastasis in vitro
10.1016/j.ijbiomac.2012.07.019 · 2012 · External reference
Isolation, purification, and antioxidant activities of degraded polysaccharides from Enteromorpha prolifera
10.1016/j.ijbiomac.2015.09.055 · 2015 · External reference
Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery system for enhanced bioactivity with reduced renal injury induced by NSAIDs
10.1080/10717544.2022.2026533 · 2022 · External reference
Simultaneous analysis of saccharides between fresh and processed Radix rehmanniae by HPLC and UHPLC-LTQ-Orbitrap-MS with multivariate statistical analysis
10.3390/molecules23030541 · 2018 · External reference
Structural characterization and antitumor activity of a pectic polysaccharide from Codonopsis pilosula
10.1016/j.carbpol.2013.06.079 · 2013 · External reference
Antioxidant activities of sulfated Codonopsis polysaccharides in acute oxidative stress
10.1111/jfbc.13974 · 2021 · External reference
Phosphorylation modification, structural characterization, antioxidant and DNA protection capacities of polysaccharides from Asarum Sieboldii miq
10.1002/cbdv.202301781 · 2024 · External reference
Immunomodulatory function and anti-tumor mechanism of natural polysaccharides: a review
10.3389/fimmu.2023.1147641 · 2023 · External reference
Structural characterization of a water-soluble polysaccharide from the roots of Codonopsis pilosula and its immunity activity
10.1016/j.ijbiomac.2008.06.009 · 2008 · External reference
Extraction of polysaccharides from Codonopsis pilosula by fermentation with response surface methodology
10.1002/fsn3.1958 · 2020 · External reference
Effects of different drying methods on the drying characteristics and quality of codonopsis pilosulae slices
10.3390/foods12061323 · 2023 · External reference
Immunostimulant, anti-inflammatory, and antinociceptive effects of a mushroom-derived (1→3), (1→6)-β-D-glucan: in vivo and in vitro models
10.1016/j.ijbiomac.2025.148508 · 2025 · External reference
Structure analysis of water-soluble polysaccharide CPPS3 isolated from Codonopsis pilosula
10.1016/j.fitote.2009.08.011 · 2010 · External reference
Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro
10.1016/j.ijbiomac.2017.06.023 · 2017 · External reference
Codonopsis pilosula polysaccharide attenuates cecal ligation and puncture sepsis via circuiting regulatory T cells in mice
10.1097/shk.0000000000000091 · 2014 · External reference
The shiitake mushroom-derived immuno-stimulant lentinan protects against murine malaria blood-stage infection by evoking adaptive immune-responses
10.1016/j.intimp.2009.01.010 · 2009 · External reference
Codonopsis pilosula polysaccharide alleviates ulcerative colitis by modulating gut microbiota and SCFA/GPR/NLRP3 pathway
10.1016/j.jep.2024.118928 · External reference
An inulin-type fructan CP-A from Codonopsis pilosula combined with 5-Fluorouracil alleviates colitis-associated tumorigenesis via inhibition of EGFR/AKT/ERK signaling pathway and regulation of intestinal flora
10.1016/j.ijbiomac.2025.142655 · External reference
Structural elucidation and anti-tumor activity of a polysaccharide (CP2-S) from Cordyceps militaris fruit bodies
10.3390/polym16141972 · 2024 · External reference
A highly branched arabinogalactan from Codonopsis pilosula: structural insights and hematopoietic-protective mechanism
10.1016/j.ijbiomac.2025.147848 · 2025 · External reference
Structural features and complement fixing activity of polysaccharides from Codonopsis pilosula Nannf. var. modesta L.T.Shen roots
10.1016/j.carbpol.2014.07.036 · 2014 · External reference
Content of polysaccharide and 5-hydroxymethyl furfural (5-HMF) in Codonopsis Radix after cooked with rice and its impact on rabbit gastrointestinal smooth muscle in vitro
10.7501/j.issn.0253-2670.2017.01.021 · 2017 · External reference
A polysaccharide isolated from Codonopsis pilosula with immunomodulation effects both in vitro and in vivo
10.3390/molecules24203632 · 2019 · External reference
Structural features of pectic polysaccharides from stems of two species of Radix Codonopsis and their antioxidant activities
10.1016/j.ijbiomac.2020.05.083 · 2020 · External reference
New pectic polysaccharides from Codonopsis pilosula and Codonopsis tangshen: structural characterization and cellular antioxidant activities
10.1002/jsfa.11261 · 2021 · External reference
A pectic polysaccharide from Codonopsis pilosula alleviates inflammatory response and oxidative stress of aging mice via modulating intestinal Microbiota-Related gut-liver axis
10.3390/antiox12091781 · 2023 · External reference