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References from Novel bioactive compounds in the treatment of osteoporosis: chemistry-driven discovery from preclinical validation to clinical translation. Local targets link to admitted publications; unresolved targets remain external evidence.
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High bone density due to a mutation in LDL-receptor-related protein 5
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Cathepsin K inhibitors for osteoporosis and potential off-target effects
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Romosozumab treatment in postmenopausal women with osteoporosis
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Treatment sequence matters: anabolic and antiresorptive therapy for osteoporosis
10.1002/jbmr.3051 · 2017 · External reference
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10.1038/aps.2009.9 · 2009 · External reference
A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis
10.1016/j.bioactmat.2021.09.015 · 2022 · External reference
Explanations for the difference in rates of cardiovascular events in a trial of alendronate and romosozumab
10.1007/s00198-020-05379-z · 2020 · External reference
Denosumab for prevention of fractures in postmenopausal women with osteoporosis
10.1056/nejmoa0809493 · 2009 · External reference
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10.1056/nejmoa0808692 · 2010 · External reference
Vertebral fractures after discontinuation of denosumab: a post hoc analysis of the randomized placebo-controlled FREEDOM trial and its extension
10.1002/jbmr.3337 · 2018 · External reference
The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial
10.1007/s13539-011-0034-6 · 2011 · External reference
Use of bone turnover markers in postmenopausal osteoporosis
10.1016/s2213-8587(17)30184-5 · 2017 · External reference
A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo
10.1172/jci119404 · 1997 · External reference
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
10.1038/ng.2249 · 2012 · External reference
Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial
10.1001/jama.282.7.637 · 1999 · External reference
Targeting cellular senescence prevents age-related bone loss in mice
10.1038/nm.4385 · 2017 · External reference
A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair
10.1038/ncomms11505 · 2016 · External reference
Tetracycline-based histological analysis of bone remodeling
10.1007/bf02058664 · 1969 · External reference
Identification of HSP90 inhibitors as a novel class of senolytics
10.1038/s41467-017-00314-z · 2017 · External reference
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
10.1126/science.273.5279.1236 · 1996 · External reference
BPS804 anti-sclerostin antibody in adults with moderate osteogenesis imperfecta: results of a randomized phase 2a trial
10.1002/jbmr.3143 · 2017 · External reference
Ospemifene 12-month safety and efficacy in postmenopausal women with vulvar and vaginal atrophy
10.3109/13697137.2013.834493 · 2014 · External reference
A phase 2, randomized, placebo-controlled, dose-ranging study of the calcium-sensing receptor antagonist MK-5442 in the treatment of postmenopausal women with osteoporosis
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Calcimimetic and calcilytic therapies for inherited disorders of the calcium-sensing receptor signalling pathway
10.1111/bph.14086 · 2018 · External reference
Effects of the Src kinase inhibitor saracatinib (AZD0530) on bone turnover in healthy men: a randomized, double-blind, placebo-controlled, multiple-ascending-dose phase I trial
10.1359/jbmr.090830 · 2010 · External reference
Binding selectivity of abaloparatide for PTH-type-1-receptor conformations and effects on downstream signaling
10.1210/en.2015-1726 · 2016 · External reference
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10.1038/nature11000 · 2012 · External reference
Senolytics decrease senescent cells in humans: preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
10.1016/j.ebiom.2019.08.069 · 2019 · External reference
Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the ESCEO and IOF
10.1007/s00198-019-05104-5 · 2019 · External reference
Bone-specific drug delivery systems: approaches via chemical modification of bone-seeking agents
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10.1038/nchembio.118 · 2008 · External reference
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10.1021/jm801007z · 2008 · External reference
A phase IB multicentre dose-determination study of BHQ880 in combination with anti-myeloma therapy and zoledronic acid in patients with relapsed or refractory multiple myeloma and prior skeletal-related events
10.1111/bjh.13056 · 2014 · External reference
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10.1172/jci6610 · 1999 · External reference
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
10.1007/s00198-006-0172-4 · 2006 · External reference
Highly accurate protein structure prediction with AlphaFold
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10.1002/jbmr.5650090802 · 1994 · External reference
Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus
10.1002/jbmr.2405 · 2015 · External reference
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
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Osteoporosis treatment: recent developments and ongoing challenges
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Estrogen and the skeleton
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Senolytic drugs: from discovery to translation
10.1111/joim.13141 · 2020 · External reference
An overview of current and emerging SERMs
10.1016/j.jsbmb.2014.03.003 · 2014 · External reference
Regulation of osteoblast differentiation by transcription factors
10.1002/jcb.20958 · 2006 · External reference
Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
10.1016/s0092-8674(01)00206-9 · 2001 · External reference
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL
10.1359/jbmr.081112 · 2009 · External reference
Prodrug strategies in anticancer chemotherapy
10.1002/cmdc.200700159 · 2008 · External reference
Targeting the Wnt/beta-catenin pathway in cancer: update on effectors and inhibitors
10.1016/j.ctrv.2017.11.002 · 2018 · External reference
Regulation of bone mass by Wnt signaling
10.1172/jci28551 · 2006 · External reference
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
10.1016/s0092-8674(00)81569-x · 1998 · External reference
Bench to bedside: elucidation of the OPG-RANK-RANKL pathway and the development of denosumab
10.1038/nrd3705 · 2012 · External reference
Romosozumab (sclerostin monoclonal antibody) versus teriparatide in postmenopausal women with osteoporosis transitioning from oral bisphosphonate therapy: a randomised, open-label, phase 3 trial
10.1016/s0140-6736(17)31613-6 · 2017 · External reference
Two years of denosumab and teriparatide administration in postmenopausal women with osteoporosis (the DATA Extension Study): a randomized controlled trial
10.1210/jc.2013-4440 · 2014 · External reference
Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial
10.1016/s0140-6736(15)61120-5 · 2015 · External reference
Regulation of myostatin activity and muscle growth
10.1073/pnas.151270098 · 2001 · External reference
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
10.1074/jbc.m413274200 · 2005 · External reference
Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease
10.1124/pr.111.004846 · 2012 · External reference
(-)-Epigallocatechin-3-gallate (EGCG) enhances osteogenic differentiation of human bone marrow mesenchymal stem cells
10.3390/molecules23123221 · 2018 · External reference
The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis
10.1186/s12967-018-1425-7 · 2018 · External reference
A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts
10.1016/j.biomaterials.2015.02.007 · 2015 · External reference
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
10.1101/gr.3437105 · 2005 · External reference
LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption
10.1038/nm.4076 · 2016 · External reference
What old means to bone
10.1016/j.tem.2010.01.010 · 2010 · External reference
Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial
10.7326/0003-4819-146-12-200706190-00005 · 2007 · External reference
Romosozumab in postmenopausal women with low bone mineral density
10.1056/nejmoa1305224 · 2014 · External reference
Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study
10.1016/s2213-8587(19)30346-8 · 2019 · External reference
Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a randomized clinical trial
10.1001/jama.2016.11136 · 2016 · External reference
Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis
10.1111/nyas.12145 · 2013 · External reference
Merck &Co. drops osteoporosis drug odanacatib
10.1038/nrd.2016.207 · 2016 · External reference
Effect of L-000845704, an alphaVbeta3 integrin antagonist, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women
10.1210/jc.2004-2126 · 2005 · External reference
Pharmacodynamic effects on biochemical markers of bone turnover and pharmacokinetics of the cathepsin K inhibitor ONO-5334 in an ascending multiple-dose, phase 1 study
10.1177/0091270011399080 · 2012 · External reference
Evidence for osteocyte regulation of bone homeostasis through RANKL expression
10.1038/nm.2452 · 2011 · External reference
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
10.1056/nejm200105103441904 · 2001 · External reference
Calcimimetic and calcilytic drugs: feats, flops, and futures
10.1007/s00223-015-0052-z · 2016 · External reference
Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl
10.1124/jpet.103.057273 · 2004 · External reference
Exploring the osteogenic potential of semisynthetic triterpenes from Combretum leprosum: an in vitro and in silico study
10.1007/s11626-024-00928-w · 2024 · External reference
Resveratrol increases bone mineral density and bone alkaline phosphatase in obese men: a randomized placebo-controlled trial
10.1210/jc.2014-2799 · 2014 · External reference
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
10.1002/jbmr.173 · 2011 · External reference
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture
10.1002/jcb.20308 · 2005 · External reference
Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression
10.1016/s8756-3282(01)00642-1 · 2002 · External reference
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity
10.1073/pnas.0711263105 · 2008 · External reference
Effects of bazedoxifene/conjugated estrogens on the endometrium and bone: a randomized trial
10.1210/jc.2013-1707 · 2014 · External reference
Osteoporosis: now and the future
10.1016/s0140-6736(10)62349-5 · 2011 · External reference
A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density
10.1002/jbmr.2351 · 2015 · External reference
Review of nonprimate, large animal models for osteoporosis research
10.1359/jbmr.080516 · 2008 · External reference
Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial
10.1155/2014/459165 · 2014 · External reference
Bisphosphonates: the first 40 years
10.1016/j.bone.2011.04.022 · 2011 · External reference
Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
10.1007/s00198-007-0540-8 · 2008 · External reference
Romosozumab or alendronate for fracture prevention in women with osteoporosis
10.1056/nejmoa1708322 · 2017 · External reference
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
10.1073/pnas.95.23.13453 · 1998 · External reference
Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research
10.1002/jbmr.1998 · 2014 · External reference
Green tea and bone metabolism
10.1016/j.nutres.2009.06.008 · 2009 · External reference
Multiple-dose, safety, pharmacokinetic, and pharmacodynamic study of sotatercept (ActRIIA-IgG1), a novel erythropoietic agent, in healthy postmenopausal women
10.1002/jcph.160 · 2013 · External reference
Ginseng saponins and the treatment of osteoporosis: mini literature review
10.5142/jgr.2013.37.261 · 2013 · External reference
Selective androgen receptor modulators: current knowledge and clinical applications
10.1016/j.sxmr.2018.09.006 · 2019 · External reference
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
10.1016/0092-8674(91)90499-o · 1991 · External reference
Cathepsin K inhibitors: a novel target for osteoporosis therapy
10.1038/sj.clpt.6100450 · 2008 · External reference
Bisphosphonates in cancer therapy
10.1016/j.canlet.2007.07.007 · 2007 · External reference
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems
10.1038/nri2062 · 2007 · External reference
Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin–BMP signaling
10.1002/jbmr.21 · 2010 · External reference
Structure-guided blockade of CSF1R kinase in tenosynovial giant-cell tumor
10.1056/nejmoa1411366 · 2015 · External reference
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
10.1056/nejmoa030847 · 2003 · External reference
Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial
10.1016/s0140-6736(13)60856-9 · 2013 · External reference
Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety
10.1080/01926230252929882 · 2002 · External reference
Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates
10.1006/bbrc.1999.1499 · 1999 · External reference
Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards
10.1007/s00198-010-1501-1 · 2011 · External reference
Spatiotemporal complexity and druggability of PTH1R: insights from small molecules and peptides
10.1016/j.mce.2026.112814 · 2026 · External reference
Integrating metabolomics and network pharmacology to study the mechanism of Er-Xian decoction in improving intervertebral disc degeneration
10.1016/j.jep.2025.119702 · 2025 · External reference
Osteogenic effects of flavonoid aglycones from an osteoprotective fraction of Drynaria fortunei — an in vitro efficacy study
10.1016/j.phymed.2011.01.022 · 2011 · External reference
miR-214 targets ATF4 to inhibit bone formation
10.1038/nm.3026 · 2013 · External reference
Development of controlled drug delivery systems for bone fracture-targeted therapeutic delivery: a review
10.1016/j.ejpb.2018.02.023 · 2018 · External reference
Icariin promotes osteogenic differentiation of rat bone marrow stromal cells by activating the ERα-Wnt/β-catenin signaling pathway
10.1016/j.biopha.2016.09.107 · 2016 · External reference
Extracellular targeted protein degradation: an emerging modality for drug discovery
10.1038/s41573-023-00833-z · 2024 · External reference
Bisphosphonates for osteoporosis — where do we go from here?
10.1056/nejmp1202619 · 2012 · External reference
Effect of naringin collagen graft on bone formation
10.1016/j.biomaterials.2005.11.009 · 2006 · External reference
Quercetin as an agent for protecting the bone: a review of the current evidence
10.3390/ijms21176448 · 2020 · External reference
Icaritin, a novel plant-derived osteoinductive agent, enhances the osteogenic differentiation of human bone marrow- and human adipose tissue-derived mesenchymal stem cells
10.3892/ijmm.2017.2906 · 2017 · External reference
Icariin inhibits RANKL-induced osteoclastogenesis via modulation of the NF-κB and MAPK signaling pathways
10.1016/j.bbrc.2018.11.201 · 2019 · External reference
The role of traditional Chinese medicines in osteogenesis and angiogenesis
10.1002/ptr.4959 · 2014 · External reference
The Hedgehog signalling pathway in bone formation
10.1038/ijos.2015.14 · 2015 · External reference
Fisetin is a senotherapeutic that extends health and lifespan
10.1016/j.ebiom.2018.09.015 · 2018 · External reference
Flavonoids of Herba Epimedii regulate osteogenesis of human mesenchymal stem cells through BMP and Wnt/beta-catenin signaling pathway
10.1016/j.mce.2009.08.012 · 2010 · External reference
A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy
10.1038/nm.2617 · 2012 · External reference
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis
10.1016/j.cmet.2006.05.012 · 2006 · External reference
Structure and dynamics of the active human parathyroid hormone receptor-1
10.1126/science.aav7942 · 2019 · External reference
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
10.1111/acel.12344 · 2015 · External reference
Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a randomized clinical trial
10.1001/jama.2016.11136 · ExternalCitation · doi-reference
Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial
10.1001/jama.282.7.637 · ExternalCitation · doi-reference
Prodrug strategies in anticancer chemotherapy
10.1002/cmdc.200700159 · ExternalCitation · doi-reference
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
10.1002/jbmr.173 · ExternalCitation · doi-reference
The US postmarketing surveillance study of adult osteosarcoma and teriparatide: study design and findings from the first 7 years
10.1002/jbmr.1768 · ExternalCitation · doi-reference
Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research
10.1002/jbmr.1998 · ExternalCitation · doi-reference
Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin–BMP signaling
10.1002/jbmr.21 · ExternalCitation · doi-reference
A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density
10.1002/jbmr.2351 · ExternalCitation · doi-reference
Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus
10.1002/jbmr.2405 · ExternalCitation · doi-reference
Treatment sequence matters: anabolic and antiresorptive therapy for osteoporosis
10.1002/jbmr.3051 · ExternalCitation · doi-reference
BPS804 anti-sclerostin antibody in adults with moderate osteogenesis imperfecta: results of a randomized phase 2a trial
10.1002/jbmr.3143 · ExternalCitation · doi-reference
The amazing osteocyte
10.1002/jbmr.320 · ExternalCitation · doi-reference
Vertebral fractures after discontinuation of denosumab: a post hoc analysis of the randomized placebo-controlled FREEDOM trial and its extension
10.1002/jbmr.3337 · ExternalCitation · doi-reference
Change in bone density and reduction in fracture risk: a meta-regression of published trials
10.1002/jbmr.3641 · ExternalCitation · doi-reference
The diagnosis of osteoporosis
10.1002/jbmr.5650090802 · ExternalCitation · doi-reference
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture
10.1002/jcb.20308 · ExternalCitation · doi-reference
Regulation of osteoblast differentiation by transcription factors
10.1002/jcb.20958 · ExternalCitation · doi-reference
Multiple-dose, safety, pharmacokinetic, and pharmacodynamic study of sotatercept (ActRIIA-IgG1), a novel erythropoietic agent, in healthy postmenopausal women
10.1002/jcph.160 · ExternalCitation · doi-reference
The role of traditional Chinese medicines in osteogenesis and angiogenesis
10.1002/ptr.4959 · ExternalCitation · doi-reference
Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates
10.1006/bbrc.1999.1499 · ExternalCitation · doi-reference
Tetracycline-based histological analysis of bone remodeling
10.1007/bf02058664 · ExternalCitation · doi-reference
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
10.1007/s00198-006-0172-4 · ExternalCitation · doi-reference
Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
10.1007/s00198-007-0540-8 · ExternalCitation · doi-reference
Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards
10.1007/s00198-010-1501-1 · ExternalCitation · doi-reference
Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the ESCEO and IOF
10.1007/s00198-019-05104-5 · ExternalCitation · doi-reference
Explanations for the difference in rates of cardiovascular events in a trial of alendronate and romosozumab
10.1007/s00198-020-05379-z · ExternalCitation · doi-reference
Calcimimetic and calcilytic drugs: feats, flops, and futures
10.1007/s00223-015-0052-z · ExternalCitation · doi-reference
Exploring the osteogenic potential of semisynthetic triterpenes from Combretum leprosum: an in vitro and in silico study
10.1007/s11626-024-00928-w · ExternalCitation · doi-reference
The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial
10.1007/s13539-011-0034-6 · ExternalCitation · doi-reference
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
10.1016/0092-8674(91)90499-o · ExternalCitation · doi-reference
Icariin inhibits RANKL-induced osteoclastogenesis via modulation of the NF-κB and MAPK signaling pathways
10.1016/j.bbrc.2018.11.201 · ExternalCitation · doi-reference
A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis
10.1016/j.bioactmat.2021.09.015 · ExternalCitation · doi-reference
Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
10.1016/j.biocel.2008.06.010 · ExternalCitation · doi-reference
Effect of naringin collagen graft on bone formation
10.1016/j.biomaterials.2005.11.009 · ExternalCitation · doi-reference
A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts
10.1016/j.biomaterials.2015.02.007 · ExternalCitation · doi-reference
Icariin promotes osteogenic differentiation of rat bone marrow stromal cells by activating the ERα-Wnt/β-catenin signaling pathway
10.1016/j.biopha.2016.09.107 · ExternalCitation · doi-reference
Bisphosphonates: the first 40 years
10.1016/j.bone.2011.04.022 · ExternalCitation · doi-reference
Bisphosphonates in cancer therapy
10.1016/j.canlet.2007.07.007 · ExternalCitation · doi-reference
Proteolysis-targeting chimeras as therapeutics and tools for biological discovery
10.1016/j.cell.2019.11.031 · ExternalCitation · doi-reference
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis
10.1016/j.cmet.2006.05.012 · ExternalCitation · doi-reference
Targeting the Wnt/beta-catenin pathway in cancer: update on effectors and inhibitors
10.1016/j.ctrv.2017.11.002 · ExternalCitation · doi-reference
Fisetin is a senotherapeutic that extends health and lifespan
10.1016/j.ebiom.2018.09.015 · ExternalCitation · doi-reference
Senolytics decrease senescent cells in humans: preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
10.1016/j.ebiom.2019.08.069 · ExternalCitation · doi-reference
Development of controlled drug delivery systems for bone fracture-targeted therapeutic delivery: a review
10.1016/j.ejpb.2018.02.023 · ExternalCitation · doi-reference
Integrating metabolomics and network pharmacology to study the mechanism of Er-Xian decoction in improving intervertebral disc degeneration
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