Research graph
References from Multi-omics profiling reveals microbiota–gut–brain axis dysregulation in an LPS-induced model of sepsis-associated encephalopathy. Local targets link to admitted publications; unresolved targets remain external evidence.
Role of Legionella pneumophila outer membrane vesicles in host-pathogen interaction
10.3389/fmicb.2023.1270123 · 2023 · External reference
Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent
10.1002/ibd.21092 · 2010 · External reference
Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis
10.1016/j.chom.2022.02.004 · 2022 · External reference
Sepsis and the brain: a review for acute and general physicians
10.7861/clinmed.2022-0346 · 2022 · External reference
The leaky gut and the gut microbiome in sepsis - targets in research and treatment
10.1042/cs20220777 · 2023 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
Modeling gut-brain interactions in zebrafish
10.1016/j.brainresbull.2019.03.003 · 2019 · External reference
UPARSE: highly accurate OTU sequences from microbial amplicon reads
10.1038/nmeth.2604 · 2013 · External reference
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021
10.1097/ccm.0000000000005337 · 2021 · External reference
Sepsis-induced gut dysbiosis mediates the susceptibility to sepsis-associated encephalopathy in mice
10.1128/msystems.01399-21 · 2022 · External reference
The intestinal microenvironment in sepsis
10.1016/j.bbadis.2017.03.005 · 2017 · External reference
Association between gut microbiota and delirium in acutely ill older adults
10.1093/gerona/glad074 · 2023 · External reference
Legionella pneumophila
10.1016/j.tim.2021.04.005 · 2021 · External reference
The role of glutathione peroxidase-1 in health and disease
10.1016/j.freeradbiomed.2022.06.004 · 2022 · External reference
Pre-operative status of gut microbiota predicts post-operative delirium in patients with gastric cancer
10.3389/fpsyt.2022.944236 · 2022 · External reference
ProteoWizard: open source software for rapid proteomics tools development
10.1093/bioinformatics/btn323 · 2008 · External reference
Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity
10.1038/s41467-020-15545-w · 2020 · External reference
Enteric dysbiosis is associated with sepsis in patients
10.1096/fj.201900398rr · 2019 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents
10.1016/j.blre.2020.100694 · 2021 · External reference
Fecal microbiota transplantation and short-chain fatty acids reduce sepsis mortality by remodeling antibiotic-induced gut microbiota disturbances
10.3389/fimmu.2022.1063543 · 2022 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
FLASH: fast length adjustment of short reads to improve genome assemblies
10.1093/bioinformatics/btr507 · 2011 · External reference
Prostaglandin E(2) as a regulator of immunity to pathogens
10.1016/j.pharmthera.2017.12.008 · 2018 · External reference
A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing
10.1016/j.mucimm.2025.04.004 · 2025 · External reference
Prostaglandin E(2) receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation
10.1136/gutjnl-2020-322146 · 2021 · External reference
Bifidobacterium and Lactobacillus improve inflammatory bowel disease in zebrafish of different ages by regulating the intestinal mucosal barrier and microbiota
10.1016/j.lfs.2023.121699 · 2023 · External reference
Legionella pneumophila and protozoan hosts: implications for the control of hospital and potable water systems
10.3390/pathogens9040286 · 2020 · External reference
Activation and expansion of presynaptic signaling foci drives presynaptic homeostatic plasticity
10.1016/j.neuron.2022.08.016 · 2022 · External reference
Development of a zebrafish sepsis model for high-throughput drug discovery
10.2119/molmed.2016.00188 · 2017 · External reference
Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction
10.1186/s12964-025-02224-w · 2025 · External reference
A transgenic zebrafish model of neutrophilic inflammation
10.1182/blood-2006-05-024075 · 2006 · External reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · 2012 · External reference
Metagenomic biomarker discovery and explanation
10.1186/gb-2011-12-6-r60 · 2011 · External reference
Sepsis-associated brain injury: underlying mechanisms and potential therapeutic strategies for acute and long-term cognitive impairments
10.1186/s12974-022-02464-4 · 2022 · External reference
Bacterial dissemination to the brain in sepsis
10.1164/rccm.201708-1559oc · 2018 · External reference
The third international consensus definitions for sepsis and septic shock (Sepsis-3)
10.1001/jama.2016.0287 · 2016 · External reference
XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
10.1021/ac051437y · 2006 · External reference
The spectrum of sepsis-associated encephalopathy: a clinical perspective
10.1186/s13054-023-04655-8 · 2023 · External reference
Endothelial TREM-1 mediates sepsis-induced blood–brain barrier disruption and cognitive impairment via the PI3K/Akt pathway
10.1186/s12974-025-03469-5 · 2025 · External reference
Altered intestinal microbiome and metabolome correspond to the clinical outcome of sepsis
10.1186/s13054-023-04412-x · 2023 · External reference
The use of zebrafish (Danio rerio) as biomedical models
10.1093/af/vfz020 · 2019 · External reference
Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses
10.1021/acs.jproteome.5b00354 · 2015 · External reference
Hiding in the yolk: A unique feature of Legionella pneumophila infection of zebrafish
10.1371/journal.ppat.1011375 · 2023 · External reference
Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy
10.1128/aem.00062-07 · 2007 · External reference
Sodium butyrate relieves cerebral ischemia-reperfusion injury in mice by inhibiting JNK/STAT pathway
10.26355/eurrev_201902_17138 · 2019 · External reference
Global metabolic profiling of animal and human tissues via UPLC-MS
10.1038/nprot.2012.135 · 2013 · External reference
Modeling inflammation in zebrafish for the development of anti-inflammatory drugs
10.3389/fcell.2020.620984 · 2020 · External reference
Transcriptional response to hypoxia: the role of HIF-1-associated co-regulators
10.3390/cells12050798 · 2023 · External reference
Inhibition of neutrophil extracellular traps alleviates blood-brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy
10.1186/s12974-025-03395-6 · 2025 · External reference
Interfering TRIB3 protects the blood brain barrier through PI3K/Akt pathway to alleviate cerebral ischemia-reperfusion injury in diabetes mellitus mice
10.1016/j.cbi.2023.110807 · 2024 · External reference
The manipulation of cell suspensions from zebrafish intestinal mucosa contributes to understanding enteritis
10.3389/fimmu.2023.1193977 · 2023 · External reference