Research graph
References from Effects of dietary fucoidan and exercise on the gut microbiome, fecal metabolome, and tumor-related responses in a murine colorectal cancer model. Local targets link to admitted publications; unresolved targets remain external evidence.
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
10.1038/s41587-019-0209-9 · 2019 · External reference
Exercise‐induced changes to the human gut microbiota and implications for colorectal cancer: a narrative review
10.1113/jp283702 · 2022 · External reference
taxize: taxonomic search and retrieval in R
10.12688/f1000research.2-191.v2 · 2013 · External reference
Interplay between exercise and gut microbiome in the context of human health and performance
10.3389/fnut.2021.637010 · 2021 · External reference
Investigating fucoidan blend supplementation and resistance training in humans: a parallel randomized controlled trial design
10.1038/s41598-025-24066-9 · 2025 · External reference
PICRUSt2 for prediction of metagenome functions
10.1038/s41587-020-0548-6 · 2020 · External reference
Endocrine responses after a single bout of moderate aerobic exercise in healthy adult humans
10.32725/jab.2018.004 · 2019 · External reference
Microbial degradation of complex carbohydrates in the gut
10.4161/gmic.19897 · 2012 · External reference
Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer
10.3892/ol.2011.254 · 2011 · External reference
The composition of the gut microbiota shapes the colon mucus barrier
10.15252/embr.201439263 · 2015 · External reference
Modulation effect of sulfated polysaccharide from Sargassum fusiforme on gut microbiota and their metabolites in vitro fermentation
10.3389/fnut.2024.1400063 · 2024 · External reference
Seaweeds in the oncology arena: Anti-cancer potential of fucoidan as a drug—A review
10.3390/molecules27186032 · 2022 · External reference
KEGG for taxonomy-based analysis of pathways and genomes
10.1093/nar/gkac963 · 2023 · External reference
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition
10.1186/1750-1326-9-36 · 2014 · External reference
Brown algae-derived polysaccharides: From sustainable bioprocessing to industrial applications
10.3390/polysaccharides7010010 · 2026 · External reference
Gut microbiota, its role in induction of Alzheimer’s disease pathology, and possible therapeutic interventions: special focus on anthocyanins
10.3390/cells9040853 · 2020 · External reference
Pheatmap: pretty heatmaps
10.32614/cran.package.pheatmap · 2019 · External reference
Moderate exercise has limited but distinguishable effects on the mouse microbiome
10.1128/msystems.00006-17 · 2017 · External reference
Fucoidan enhances the anti-tumor effect of anti-PD-1 immunotherapy by regulating gut microbiota
10.1039/d3fo04807a · 2024 · External reference
Toxicological evaluation of fucoidan extracted from Laminaria japonica in Wistar rats
10.1016/j.fct.2004.12.001 · 2005 · External reference
microeco: an R package for data mining in microbial community ecology
10.1093/femsec/fiaa255 · 2021 · External reference
The gut microbiota, bacterial metabolites and colorectal cancer
10.1038/nrmicro3344 · 2014 · External reference
The effect of probiotics on the production of short-chain fatty acids by human intestinal microbiome
10.3390/nu12041107 · 2020 · External reference
Unresolved reference
2024 · External reference
Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry
10.1016/j.foodhyd.2023.108784 · 2023 · External reference
Host-gut microbiota metabolic interactions
10.1126/science.1223813 · 2012 · External reference
Optimizing physical fitness in chronic stroke patients: the impact of exercise training modality and dosage on maximal and sub-maximal fitness–a systematic review and meta-analysis
10.2340/jrm.v57.43359 · 2025 · External reference
Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice
10.1186/s40168-018-0440-5 · 2018 · External reference
An overview of extraction and purification techniques of seaweed dietary fibers for immunomodulation on gut microbiota
10.1016/j.tifs.2019.08.011 · 2019 · External reference
A randomized placebo-controlled trial of an oral preparation of high molecular weight fucoidan in patients with type 2 diabetes with evaluation of taste sensitivity
10.33160/yam.2019.03.003 · 2019 · External reference
Preclinical development of ipilimumab and nivolumab combination immunotherapy: mouse tumor models, in vitro functional studies, and cynomolgus macaque toxicology
10.1371/journal.pone.0161779 · 2016 · External reference
Impacts of oxidative stress and PI3K/AKT/mTOR on metabolism and the future direction of investigating fucoidan-modulated metabolism
10.3390/antiox11050911 · 2022 · External reference
Exercise and colorectal cancer: a systematic review and meta-analysis of exercise safety, feasibility and effectiveness
10.1186/s12966-020-01021-7 · 2020 · External reference
Type, intensity, and duration of exercise as regulator of gut microbiome profile
10.1249/jsr.0000000000000940 · 2022 · External reference
Efficacy of low-molecular-weight fucoidan as a supplemental therapy in metastatic colorectal cancer patients: A double-blind randomized controlled trial
10.3390/md15040122 · 2017 · External reference
The auxiliary effects of low-molecular-weight fucoidan in locally advanced rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy before surgery: a double-blind, randomized, placebo-controlled study
10.1177/15347354231187153 · 2023 · External reference
The gut microbiota modulates host energy and lipid metabolism in mice
10.1194/jlr.m002774 · 2010 · External reference
Biological activities of fucoidan and the factors mediating its therapeutic effects: A review of recent studies
10.3390/md17030183 · 2019 · External reference
Welcome to the Tidyverse
10.21105/joss.01686 · 2019 · External reference
Moderate-intensity physical exercise affects the exercise performance and gut microbiota of mice
10.3389/fcimb.2021.712381 · 2021 · External reference
Microbiome-metabolomics reveals prebiotic benefits of fucoidan supplementation in mice
10.3390/jmse9050505 · 2021 · External reference
Diet is a stronger covariate than exercise in determining gut microbial richness and diversity
10.3390/nu14122507 · 2022 · External reference
colorspace: A toolbox for manipulating and assessing colors and palettes
10.21105/joss.07120 · 2020 · External reference
Physical exercise as a potential adjuvant therapy: effects on inflammation and nutrition in colorectal cancer patients—a systematic review and meta-analysis
10.3389/fnut.2025.1612674 · 2025 · External reference
Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome
10.1038/s41392-019-0074-5 · 2019 · External reference
Preparation methods, biological activities, and potential applications of marine algae oligosaccharides: A review
10.1016/j.fshw.2022.07.038 · 2023 · External reference
Toxicological evaluation of fucoidan extracted from Laminaria japonica in Wistar rats
10.1016/j.fct.2004.12.001 · ExternalCitation · doi-reference
Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry
10.1016/j.foodhyd.2023.108784 · ExternalCitation · doi-reference
Preparation methods, biological activities, and potential applications of marine algae oligosaccharides: A review
10.1016/j.fshw.2022.07.038 · ExternalCitation · doi-reference
An overview of extraction and purification techniques of seaweed dietary fibers for immunomodulation on gut microbiota
10.1016/j.tifs.2019.08.011 · ExternalCitation · doi-reference
The gut microbiota, bacterial metabolites and colorectal cancer
10.1038/nrmicro3344 · ExternalCitation · doi-reference
Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome
10.1038/s41392-019-0074-5 · ExternalCitation · doi-reference
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
10.1038/s41587-019-0209-9 · ExternalCitation · doi-reference
PICRUSt2 for prediction of metagenome functions
10.1038/s41587-020-0548-6 · ExternalCitation · doi-reference
Investigating fucoidan blend supplementation and resistance training in humans: a parallel randomized controlled trial design
10.1038/s41598-025-24066-9 · ExternalCitation · doi-reference
Fucoidan enhances the anti-tumor effect of anti-PD-1 immunotherapy by regulating gut microbiota
10.1039/d3fo04807a · ExternalCitation · doi-reference
microeco: an R package for data mining in microbial community ecology
10.1093/femsec/fiaa255 · ExternalCitation · doi-reference
KEGG for taxonomy-based analysis of pathways and genomes
10.1093/nar/gkac963 · ExternalCitation · doi-reference
Exercise‐induced changes to the human gut microbiota and implications for colorectal cancer: a narrative review
10.1113/jp283702 · ExternalCitation · doi-reference
Host-gut microbiota metabolic interactions
10.1126/science.1223813 · ExternalCitation · doi-reference
Moderate exercise has limited but distinguishable effects on the mouse microbiome
10.1128/msystems.00006-17 · ExternalCitation · doi-reference
The auxiliary effects of low-molecular-weight fucoidan in locally advanced rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy before surgery: a double-blind, randomized, placebo-controlled study
10.1177/15347354231187153 · ExternalCitation · doi-reference
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition
10.1186/1750-1326-9-36 · ExternalCitation · doi-reference
Exercise and colorectal cancer: a systematic review and meta-analysis of exercise safety, feasibility and effectiveness
10.1186/s12966-020-01021-7 · ExternalCitation · doi-reference
Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice
10.1186/s40168-018-0440-5 · ExternalCitation · doi-reference
The gut microbiota modulates host energy and lipid metabolism in mice
10.1194/jlr.m002774 · ExternalCitation · doi-reference
Type, intensity, and duration of exercise as regulator of gut microbiome profile
10.1249/jsr.0000000000000940 · ExternalCitation · doi-reference
taxize: taxonomic search and retrieval in R
10.12688/f1000research.2-191.v2 · ExternalCitation · doi-reference
Preclinical development of ipilimumab and nivolumab combination immunotherapy: mouse tumor models, in vitro functional studies, and cynomolgus macaque toxicology
10.1371/journal.pone.0161779 · ExternalCitation · doi-reference
The composition of the gut microbiota shapes the colon mucus barrier
10.15252/embr.201439263 · ExternalCitation · doi-reference
Welcome to the Tidyverse
10.21105/joss.01686 · ExternalCitation · doi-reference
colorspace: A toolbox for manipulating and assessing colors and palettes
10.21105/joss.07120 · ExternalCitation · doi-reference
Optimizing physical fitness in chronic stroke patients: the impact of exercise training modality and dosage on maximal and sub-maximal fitness–a systematic review and meta-analysis
10.2340/jrm.v57.43359 · ExternalCitation · doi-reference
Pheatmap: pretty heatmaps
10.32614/cran.package.pheatmap · ExternalCitation · doi-reference
Endocrine responses after a single bout of moderate aerobic exercise in healthy adult humans
10.32725/jab.2018.004 · ExternalCitation · doi-reference
A randomized placebo-controlled trial of an oral preparation of high molecular weight fucoidan in patients with type 2 diabetes with evaluation of taste sensitivity
10.33160/yam.2019.03.003 · ExternalCitation · doi-reference
Moderate-intensity physical exercise affects the exercise performance and gut microbiota of mice
10.3389/fcimb.2021.712381 · ExternalCitation · doi-reference
Interplay between exercise and gut microbiome in the context of human health and performance
10.3389/fnut.2021.637010 · ExternalCitation · doi-reference
Modulation effect of sulfated polysaccharide from Sargassum fusiforme on gut microbiota and their metabolites in vitro fermentation
10.3389/fnut.2024.1400063 · ExternalCitation · doi-reference
Physical exercise as a potential adjuvant therapy: effects on inflammation and nutrition in colorectal cancer patients—a systematic review and meta-analysis
10.3389/fnut.2025.1612674 · ExternalCitation · doi-reference
Impacts of oxidative stress and PI3K/AKT/mTOR on metabolism and the future direction of investigating fucoidan-modulated metabolism
10.3390/antiox11050911 · ExternalCitation · doi-reference
Gut microbiota, its role in induction of Alzheimer’s disease pathology, and possible therapeutic interventions: special focus on anthocyanins
10.3390/cells9040853 · ExternalCitation · doi-reference
Microbiome-metabolomics reveals prebiotic benefits of fucoidan supplementation in mice
10.3390/jmse9050505 · ExternalCitation · doi-reference
Efficacy of low-molecular-weight fucoidan as a supplemental therapy in metastatic colorectal cancer patients: A double-blind randomized controlled trial
10.3390/md15040122 · ExternalCitation · doi-reference
Biological activities of fucoidan and the factors mediating its therapeutic effects: A review of recent studies
10.3390/md17030183 · ExternalCitation · doi-reference
Seaweeds in the oncology arena: Anti-cancer potential of fucoidan as a drug—A review
10.3390/molecules27186032 · ExternalCitation · doi-reference
The effect of probiotics on the production of short-chain fatty acids by human intestinal microbiome
10.3390/nu12041107 · ExternalCitation · doi-reference
Diet is a stronger covariate than exercise in determining gut microbial richness and diversity
10.3390/nu14122507 · ExternalCitation · doi-reference
Brown algae-derived polysaccharides: From sustainable bioprocessing to industrial applications
10.3390/polysaccharides7010010 · ExternalCitation · doi-reference
Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer
10.3892/ol.2011.254 · ExternalCitation · doi-reference
Microbial degradation of complex carbohydrates in the gut
10.4161/gmic.19897 · ExternalCitation · doi-reference
