Research graph
References from Mechanisms underlying the role of the oral-gut-liver axis in the promotion of liver fibrosis by periodontal disease: an interacting network of inflammation, microbiota, and barrier function. Local targets link to admitted publications; unresolved targets remain external evidence.
Oral health and liver disease: bidirectional associations-a narrative review
10.3390/dj10020016 · 2022 · External reference
From inflamed gums to infected heart: linking periodontal diseases and myocardial infarction
10.1097/crd.0000000000000898 · 2025 · External reference
Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease
10.1371/journal.pone.0185902 · 2017 · External reference
Impact of oral mesenchymal stem cells applications as a promising therapeutic target in the therapy of periodontal disease
10.3390/ijms232113419 · 2022 · External reference
The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice
10.1111/jcpe.13682 · 2022 · External reference
Periodontal therapy favorably modulates the oral-gut-hepatic axis in cirrhosis
10.1152/ajpgi.00230.2018 · 2018 · External reference
Dental prophylactic interventions are associated with lower decompensation-related hospitalizations over 2 years in cirrhosis
10.1016/j.jhepr.2026.101821 · 2026 · External reference
Innovative application of nested PCR for detection of Porphyromonas gingivalis in human highly calcified atherothrombotic plaques
10.1080/20002297.2020.1742523 · 2020 · External reference
Present and future perspectives in the treatment of liver fibrosis
10.3390/ph18091321 · 2025 · External reference
Bacteria prevalence in a large Italian population sample: a clinical and microbiological study
2016 · External reference
Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection
10.1186/s13071-021-04790-7 · 2021 · External reference
Porphyromonas gingivalis-induced production of reactive oxygen species, tumor necrosis factor-α, interleukin-6, CXCL8 and CCL2 by neutrophils from localized aggressive periodontitis and healthy donors: modulating actions of red blood cells and resolvin E1
10.1111/jre.12388 · 2017 · External reference
Porphyromonas gingivalis-derived lipopolysaccharide causes excessive hepatic lipid accumulation via activating NF-κB and JNK signaling pathways
10.1111/odi.13153 · 2019 · External reference
Liver disease and periodontal pathogens: a bidirectional relationship between liver and oral microbiota
10.3390/dj13110503 · 2025 · External reference
Deciphering the toxicological role of Porphyromonas gingivalis derived endotoxins in liver diseases
10.1016/j.etap.2021.103755 · 2021 · External reference
Porphyromonas gingivalis aggravates alcohol-related liver injury via gut microbiome-HO-1-ACSL4-dependent ferroptosis
10.3389/fmicb.2025.1554703 · 2025 · External reference
Systemic racism and racial inequities in periodontal health: the long journey from upstream determinants to downstream treatment
10.1111/prd.12559 · 2025 · External reference
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor
10.1039/c8fo00107c · 2018 · External reference
Porphyromonas gingivalis exacerbates alcoholic liver disease by altering gut microbiota composition and host immune response in mice
10.1111/jcpe.13833 · 2023 · External reference
Non-surgical periodontal therapy could improve the periodontal inflammatory status in patients with periodontitis and chronic hepatitis C
10.3390/jcm10225275 · 2021 · External reference
Bile acids contribute to the development of non-alcoholic steatohepatitis in mice
10.1016/j.jhepr.2021.100387 · 2022 · External reference
Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review
10.3389/fcvm.2023.1250263 · 2023 · External reference
Western diet-induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis
10.1096/fj.201902687r · 2020 · External reference
The global burden of periodontal disease: a narrative review on unveiling socioeconomic and health challenges
10.3390/ijerph22040624 · 2025 · External reference
Identifying a distinct fibrosis subset of NAFLD via molecular profiling and the involvement of profibrotic macrophages
10.1186/s12967-023-04300-6 · 2023 · External reference
Periodontitis is associated with incident chronic liver disease-a population-based cohort study
10.1111/liv.13985 · 2019 · External reference
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
10.1073/pnas.0511167103 · 2006 · External reference
Vascular endothelial function in periodontal disease: role of inflammation
10.1161/jaha.125.045720 · 2025 · External reference
Nonalcoholic fatty liver disease assessed by multiple tools are correlated to periodontal conditions
10.1038/s41598-026-40128-y · 2026 · External reference
Metabolic reprogramming in liver fibrosis
10.1016/j.cmet.2024.05.003 · 2024 · External reference
Water-soluble Poria cocos polysaccharide improves alcoholic liver disease via modulation of gut microbiota-mediated intestinal bile acids-farnesoid X receptor
10.1016/j.ijbiomac.2025.148202 · 2025 · External reference
Liver fibrosis: understanding the dynamics of bidirectional wound repair to inform the design of markers and therapies
10.1159/000456581 · 2017 · External reference
Trimethylamine N-oxide: a meta-organismal axis linking the gut and fibrosis
10.1186/s10020-024-00895-8 · 2024 · External reference
Diagnostic efficacy of serum Mac-2 binding protein glycosylation isomer and other markers for liver fibrosis in non-alcoholic fatty liver diseases
10.3343/alm.2021.41.3.302 · 2021 · External reference
The interventional role and mechanism of total flavonoids in lychee seeds on rats with liver fibrosis
10.1038/s41598-025-10007-z · 2025 · External reference
Association between nonalcoholic fatty liver disease scores and chronic periodontitis: a retrospective cohort study
10.1002/jper.24-0171 · 2025 · External reference
Periodontal treatment and usual care for nonalcoholic fatty liver disease: A multicenter, randomized controlled trial
10.14309/ctg.0000000000000520 · 2022 · External reference
Role of TGR5 (GPBAR1) in liver disease
10.1055/s-0038-1669940 · 2018 · External reference
Toll-like receptors in pathophysiology of liver diseases
10.4254/wjh.v8.i32.1354 · 2016 · External reference
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells
10.1002/hep.24784 · 2012 · External reference
Periodontal disease in different stages of chronic kidney disease
10.20471/acc.2019.58.04.18 · 2019 · External reference
The role of the oral microbiome in the development of diseases
10.3390/ijms24065231 · 2023 · External reference
Inflammatory cytokine variations after non-surgical periodontal therapy across periodontal stages and grades
10.3390/dj13120591 · 2025 · External reference
Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease
10.1038/srep35282 · 2016 · External reference
Periodontal disease-related nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: an emerging concept of oral-liver axis
10.1111/prd.12387 · 2021 · External reference
Nisin lantibiotic prevents NAFLD liver steatosis and mitochondrial oxidative stress following periodontal disease by abrogating oral, gut and liver dysbiosis
10.1038/s41522-024-00476-x · 2024 · External reference
Association between periodontitis and fibrotic progression of non-alcoholic fatty liver among Japanese adults
10.1111/jcpe.13415 · 2021 · External reference
Differential analysis of culturable and unculturable subgingival target microorganisms according to the stages of periodontitis
10.1007/s00784-023-04907-5 · 2023 · External reference
Antifibrotic activity of human placental amnion membrane-derived CD34+ mesenchymal stem/progenitor cell transplantation in mice with thioacetamide-induced liver injury
10.5966/sctm.2015-0343 · 2016 · External reference
Galectin-12 modulates Kupffer cell polarization to alter the progression of nonalcoholic fatty liver disease
10.1093/glycob/cwad062 · 2023 · External reference
Role of noncoding RNAs in liver fibrosis
10.3748/wjg.v29.i9.1446 · 2023 · External reference
Multidimensional intestinal barrier repair strategies for alleviating inflammatory bowel disease and gut-liver axis-associated metabolic liver disease
10.1016/j.biomaterials.2026.124409 · 2026 · External reference
Medicinal Formula Huazhi-Rougan attenuates non-alcoholic steatohepatitis through enhancing fecal bile acid excretion in mice
10.3389/fphar.2022.833414 · 2022 · External reference
Pharmacological modulation of ferroptosis as a therapeutic target for liver fibrosis
10.3389/fphar.2022.1071844 · 2022 · External reference
Association between oral microbiome alpha and beta diversity and MASLD risk: a large-scale, population-based retrospective study
10.3389/fcimb.2026.1784034 · 2026 · External reference
Probiotic-derived extracellular vesicles attenuate cholestatic liver damage via gut-liver axis
10.1016/j.phrs.2026.108152 · 2026 · External reference
Understanding the implication of autophagy in the activation of hepatic stellate cells in liver fibrosis: are we there yet
10.1002/path.5678 · 2021 · External reference
Clindamycin as an alternative option in optimizing periodontal therapy
10.3390/antibiotics10070814 · 2021 · External reference
Porphyromonas gingivalis OMVs activate macrophage-hepatic stellate cells via Thbs1/TGF-β signalling in NAFLD
10.1016/j.identj.2025.104005 · 2026 · External reference
Chronic periodontitis and non-alcoholic fatty liver disease: recent advances in mechanisms of association
10.2147/ijgm.s554833 · 2025 · External reference
Progress in research on the roles of TGR5 receptor in liver diseases
10.1080/00365521.2021.1903547 · 2021 · External reference
The liver fibrosis niche: novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix
10.1016/j.fct.2020.111556 · 2020 · External reference
Periodontal disease may induce liver fibrosis in an experimental study on Wistar rats
10.1002/jper.18-0585 · 2019 · External reference
Removal of CD5 on T cells alters their differentiation and cytokine production in an in vitro model investigating effects of P. gingivalis LPS on oral epithelial and immune cells
10.3389/fimmu.2026.1761775 · 2026 · External reference
Periodontitis and metabolic dysfunction-associated steatotic liver disease: emphasizing the clinical interplay between hepatologists and dentists
10.1007/s10266-025-01184-4 · 2026 · External reference
Odontogenic infection by Porphyromonas gingivalis exacerbates fibrosis in NASH via hepatic stellate cell activation
10.1038/s41598-020-60904-8 · 2020 · External reference
Pathogenesis of liver fibrosis and its TCM therapeutic perspectives
10.1155/2022/5325431 · 2022 · External reference
Periodontitis, coronary heart disease and myocardial infarction: treat one, benefit all
10.1097/mbc.0000000000000928 · 2020 · External reference
Development of Oral Care Chip, a novel device for quantitative detection of the oral microbiota associated with periodontal disease
10.1371/journal.pone.0229485 · 2020 · External reference
Clinical impact of microbiome in patients with decompensated cirrhosis
10.3748/wjg.v24.i34.3813 · 2018 · External reference
MicroRNAs and periodontal disease: helpful therapeutic targets
10.34172/apb.2023.048 · 2023 · External reference
Molecular characterization and cell type composition deconvolution of fibrosis in NAFLD
10.1038/s41598-021-96966-5 · 2021 · External reference
Reproducibility of a commercially available subgingival plaque sampling strategy and analysis strategy with oligonucleotide probes
10.1080/00016357.2017.1303192 · 2017 · External reference
Is periodontal inflammation associated with liver cirrhosis? a cross-sectional study
10.3390/jcm14186616 · 2025 · External reference
Fibrosis progression rate in a systematic review of placebo-treated nonalcoholic steatohepatitis
10.1111/liv.14749 · 2021 · External reference
The Yin and Yang of bile acid action on tight junctions in a model colonic epithelium
10.14814/phy2.13294 · 2017 · External reference
Metabolic dysfunction-associated steatotic liver disease and the gut microbiome: pathogenic insights and therapeutic innovations
10.1172/jci186423 · 2025 · External reference
Periodontal disease could be a potential risk factor for non-alcoholic fatty liver disease: An 11-year retrospective follow-up study
10.1007/s00784-022-04518-6 · 2022 · External reference
Isobavachalcone suppresses the TRIF-dependent signaling pathway of Toll-like receptors
10.9734/bjmmr/2013/2071 · 2022 · External reference
Diet-induced non-alcoholic fatty liver disease and associated gut dysbiosis are exacerbated by oral infection
10.3389/froh.2021.784448 · 2021 · External reference
Toward digital periodontal health: recent advances and future perspectives
10.3390/bioengineering11090937 · 2024 · External reference
Porphyromonas gingivalis indirectly elicits intestinal inflammation by altering the gut microbiota and disrupting epithelial barrier function through IL9-producing CD4+ T cells
10.1111/omi.12359 · 2022 · External reference
Bile acid-receptor TGR5 deficiency worsens liver injury in alcohol-fed mice by inducing intestinal microbiota dysbiosis
10.1016/j.jhepr.2021.100230 · 2021 · External reference
Proteomics reveals periodontitis-driven oxidative stress and lipid metabolism disruption in NAFLD
10.3389/fendo.2025.1600015 · 2025 · External reference
Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury
10.5361/jkmu1956.55.2-4_167 · 2002 · External reference
Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD
10.1038/s41574-021-00584-0 · 2022 · External reference
Novel regulators of hepatic macrophages in liver fibrosis
10.3389/fimmu.2025.1705503 · 2025 · External reference
Activation of the TGR5/cAMP/PKA/CREB axis in cholangiocytes mediates epithelial-mesenchymal transition and fibrosis in hepatolithiasis
10.1186/s13062-026-00783-7 · 2026 · External reference
Ligature-induced periodontitis exacerbates high-carbohydrate/high-fat diet-induced fatty liver in mice under non-diabetic conditions
10.1186/s12903-026-07992-6 · 2026 · External reference
Role of noncoding RNAs as biomarker and therapeutic targets for liver fibrosis
10.3727/105221615x14399878166078 · 2015 · External reference
Gut-liver axis: Pathophysiological concepts and clinical implications
10.1016/j.cmet.2022.09.017 · 2022 · External reference
Interleukin-11 signaling plays limited roles for liver fibrosis in a mouse model of metabolic dysfunction-associated steatohepatitis
10.1016/j.bbrc.2024.150938 · 2024 · External reference
Enterococcus faecium DNA in acute decompensated cirrhosis: a key player in inflammation and kidney dysfunction
10.3389/fmed.2025.1629210 · 2025 · External reference
Could there be an interplay between periodontal changes and pancreatic Malignancies
10.12998/wjcc.v11.i3.545 · 2023 · External reference
Role of nonalcoholic fatty liver disease in periodontitis: a bidirectional relationship
10.7759/cureus.63775 · 2024 · External reference
Extracellular vesicle-dependent crosstalk between hepatic stellate cells and Kupffer cells promotes their mutual activation
10.1016/j.bbadis.2025.167914 · 2025 · External reference
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice
10.1016/j.isci.2023.106346 · 2023 · External reference
Gut-liver-axis: Barrier function of liver sinusoidal endothelial cell
10.1111/jgh.15512 · 2021 · External reference
Nonalcoholic steatohepatitis exacerbates inflammatory bone destruction and macrophage NLR family pyrin domain-containing 3 inflammasome activation in ligature-induced periodontitis
10.1016/j.ajpath.2025.10.011 · 2026 · External reference
Gut-liver axis: Liver sinusoidal endothelial cells function as the hepatic barrier in colitis-induced liver injury
10.3389/fcell.2021.702890 · 2021 · External reference
Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance
10.1371/journal.ppat.1012821 · 2025 · External reference
The oral-gut-liver axis: linking periodontal microbiota to the pathogenesis of liver diseases
10.3389/fmed.2026.1810114 · 2026 · External reference
Periodontitis and systemic diseases: insights into the correlation, mechanisms, and clinical implications
10.3389/fimmu.2026.1777955 · 2026 · External reference
The correlation between periodontitis and fatty liver and the improvement of NAFLD by periodontal treatment
10.3389/froh.2026.1706821 · 2026 · External reference
The role of bile acid-activated receptor TGR5 in inflammation and liver diseases
10.3389/fphys.2026.1747341 · 2026 · External reference
TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway
10.1016/j.cbi.2022.109839 · 2022 · External reference
Future drug targets in periodontal personalised medicine-a narrative review
10.3390/jpm12030371 · 2022 · External reference
Development of a liver fibrosis treatment targeting inhibition of hepatic stellate cell activation
10.1248/yakushi.25-00126 · 2026 · External reference
Ovalbumin peptides restore intestinal barrier integrity via gut-liver axis modulation of bile salt hydrolase and bile acids crosstalk
10.1021/acs.jafc.5c07236 · 2025 · External reference
From bench to bedside: molecular mechanisms, diagnostic tools, and therapeutic strategies in liver fibrosis
10.1016/j.livres.2026.03.001 · 2026 · External reference
Mesenchymal stromal cells: promising treatment for liver cirrhosis
10.1186/s13287-022-03001-z · 2022 · External reference
Genetic susceptibility and metabolic pathways linking oral health to metabolic dysfunction-associated steatotic liver disease
10.1002/jper.70029 · 2026 · External reference
Human umbilical cord mesenchymal stem cells ameliorate liver fibrosis in vitro and in vivo: from biological characteristics to therapeutic mechanisms
10.4252/wjsc.v11.i8.548 · 2019 · External reference
Extracellular vesicles of P. gingivalis-infected macrophages induce lung injury
10.1016/j.bbadis.2021.166236 · 2021 · External reference
Gut microbiota metabolite 3-indolepropionic acid directly activates hepatic stellate cells by ROS/JNK/p38 signaling pathways
10.3390/biom13101464 · 2023 · External reference
The role of TLR4/MyD88/NF-κB pathway in periodontitis-induced liver inflammation of rats
10.1111/odi.13616 · 2021 · External reference
Protective effect of ursolic acid on the intestinal mucosal barrier in a rat model of liver fibrosis
10.3389/fphys.2019.00956 · 2019 · External reference
The gut microbiota-bile acid axis: a potential therapeutic target for liver fibrosis
10.3389/fcimb.2022.945368 · 2022 · External reference
Intestinal barrier in chronic gut and liver diseases: pathogenesis and therapeutic targets
10.1016/j.apsb.2025.08.028 · 2025 · External reference
Gut microbiota protects against liver injury and fibrosis via activation of the CYP eicosanoid pathway
10.21203/rs.3.rs-6356145/v1 · 2025 · External reference
Liver fibrosis and hepatic stellate cells: etiology, pathological hallmarks and therapeutic targets
10.3748/wjg.v22.i48.10512 · 2016 · External reference
ANGPTL4 regulates CD163 expression and Kuppfer cell polarization induced cirrhosis via TLR4/NF-κB pathway
10.1016/j.yexcr.2021.112706 · 2021 · External reference
Gut-liver axis mechanisms underlying spontaneous reversal of liver fibrosis: a gut microbiota-metabolomics analysis
10.3390/metabo16060424 · 2026 · External reference
Bile acid disorders and intestinal barrier dysfunction are involved in the development of fatty liver in laying hens
10.1016/j.psj.2024.104422 · 2024 · External reference
Gut-engineered Bacillus subtilis-mediated BAMBI delivery for the treatment of thioacetamide-induced liver fibrosis through mechanotransduction inhibition
10.3389/fbioe.2026.1817519 · 2026 · External reference
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis
10.1038/s41467-019-14138-6 · 2020 · External reference
Longitudinal changes in fibrosis markers: monitoring stiffness/fibrosis progression and prognostic outcomes in MASLD
10.1016/j.cgh.2025.07.011 · 2026 · External reference
Effect of hypertension on long-term adverse clinical outcomes and liver fibrosis progression in MASLD
10.1016/j.jhep.2025.08.017 · 2026 · External reference
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells
10.1002/hep.24784 · ExternalCitation · doi-reference
Periodontal disease may induce liver fibrosis in an experimental study on Wistar rats
10.1002/jper.18-0585 · ExternalCitation · doi-reference
Association between nonalcoholic fatty liver disease scores and chronic periodontitis: a retrospective cohort study
10.1002/jper.24-0171 · ExternalCitation · doi-reference
Genetic susceptibility and metabolic pathways linking oral health to metabolic dysfunction-associated steatotic liver disease
10.1002/jper.70029 · ExternalCitation · doi-reference
Understanding the implication of autophagy in the activation of hepatic stellate cells in liver fibrosis: are we there yet
10.1002/path.5678 · ExternalCitation · doi-reference
Periodontal disease could be a potential risk factor for non-alcoholic fatty liver disease: An 11-year retrospective follow-up study
10.1007/s00784-022-04518-6 · ExternalCitation · doi-reference
Differential analysis of culturable and unculturable subgingival target microorganisms according to the stages of periodontitis
10.1007/s00784-023-04907-5 · ExternalCitation · doi-reference
Periodontitis and metabolic dysfunction-associated steatotic liver disease: emphasizing the clinical interplay between hepatologists and dentists
10.1007/s10266-025-01184-4 · ExternalCitation · doi-reference
Nonalcoholic steatohepatitis exacerbates inflammatory bone destruction and macrophage NLR family pyrin domain-containing 3 inflammasome activation in ligature-induced periodontitis
10.1016/j.ajpath.2025.10.011 · ExternalCitation · doi-reference
Intestinal barrier in chronic gut and liver diseases: pathogenesis and therapeutic targets
10.1016/j.apsb.2025.08.028 · ExternalCitation · doi-reference
Extracellular vesicles of P. gingivalis-infected macrophages induce lung injury
10.1016/j.bbadis.2021.166236 · ExternalCitation · doi-reference
Extracellular vesicle-dependent crosstalk between hepatic stellate cells and Kupffer cells promotes their mutual activation
10.1016/j.bbadis.2025.167914 · ExternalCitation · doi-reference
Interleukin-11 signaling plays limited roles for liver fibrosis in a mouse model of metabolic dysfunction-associated steatohepatitis
10.1016/j.bbrc.2024.150938 · ExternalCitation · doi-reference
Multidimensional intestinal barrier repair strategies for alleviating inflammatory bowel disease and gut-liver axis-associated metabolic liver disease
10.1016/j.biomaterials.2026.124409 · ExternalCitation · doi-reference
TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway
10.1016/j.cbi.2022.109839 · ExternalCitation · doi-reference
Longitudinal changes in fibrosis markers: monitoring stiffness/fibrosis progression and prognostic outcomes in MASLD
10.1016/j.cgh.2025.07.011 · ExternalCitation · doi-reference
Gut-liver axis: Pathophysiological concepts and clinical implications
10.1016/j.cmet.2022.09.017 · ExternalCitation · doi-reference
Metabolic reprogramming in liver fibrosis
10.1016/j.cmet.2024.05.003 · ExternalCitation · doi-reference
Deciphering the toxicological role of Porphyromonas gingivalis derived endotoxins in liver diseases
10.1016/j.etap.2021.103755 · ExternalCitation · doi-reference
The liver fibrosis niche: novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix
10.1016/j.fct.2020.111556 · ExternalCitation · doi-reference
Porphyromonas gingivalis OMVs activate macrophage-hepatic stellate cells via Thbs1/TGF-β signalling in NAFLD
10.1016/j.identj.2025.104005 · ExternalCitation · doi-reference
Water-soluble Poria cocos polysaccharide improves alcoholic liver disease via modulation of gut microbiota-mediated intestinal bile acids-farnesoid X receptor
10.1016/j.ijbiomac.2025.148202 · ExternalCitation · doi-reference
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice
10.1016/j.isci.2023.106346 · ExternalCitation · doi-reference
Effect of hypertension on long-term adverse clinical outcomes and liver fibrosis progression in MASLD
10.1016/j.jhep.2025.08.017 · ExternalCitation · doi-reference
Bile acid-receptor TGR5 deficiency worsens liver injury in alcohol-fed mice by inducing intestinal microbiota dysbiosis
10.1016/j.jhepr.2021.100230 · ExternalCitation · doi-reference
Bile acids contribute to the development of non-alcoholic steatohepatitis in mice
10.1016/j.jhepr.2021.100387 · ExternalCitation · doi-reference
Dental prophylactic interventions are associated with lower decompensation-related hospitalizations over 2 years in cirrhosis
10.1016/j.jhepr.2026.101821 · ExternalCitation · doi-reference
From bench to bedside: molecular mechanisms, diagnostic tools, and therapeutic strategies in liver fibrosis
10.1016/j.livres.2026.03.001 · ExternalCitation · doi-reference
Probiotic-derived extracellular vesicles attenuate cholestatic liver damage via gut-liver axis
10.1016/j.phrs.2026.108152 · ExternalCitation · doi-reference
Bile acid disorders and intestinal barrier dysfunction are involved in the development of fatty liver in laying hens
10.1016/j.psj.2024.104422 · ExternalCitation · doi-reference
ANGPTL4 regulates CD163 expression and Kuppfer cell polarization induced cirrhosis via TLR4/NF-κB pathway
10.1016/j.yexcr.2021.112706 · ExternalCitation · doi-reference
Ovalbumin peptides restore intestinal barrier integrity via gut-liver axis modulation of bile salt hydrolase and bile acids crosstalk
10.1021/acs.jafc.5c07236 · ExternalCitation · doi-reference
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis
10.1038/s41467-019-14138-6 · ExternalCitation · doi-reference
Nisin lantibiotic prevents NAFLD liver steatosis and mitochondrial oxidative stress following periodontal disease by abrogating oral, gut and liver dysbiosis
10.1038/s41522-024-00476-x · ExternalCitation · doi-reference
Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD
10.1038/s41574-021-00584-0 · ExternalCitation · doi-reference
Odontogenic infection by Porphyromonas gingivalis exacerbates fibrosis in NASH via hepatic stellate cell activation
10.1038/s41598-020-60904-8 · ExternalCitation · doi-reference
Molecular characterization and cell type composition deconvolution of fibrosis in NAFLD
10.1038/s41598-021-96966-5 · ExternalCitation · doi-reference
The interventional role and mechanism of total flavonoids in lychee seeds on rats with liver fibrosis
10.1038/s41598-025-10007-z · ExternalCitation · doi-reference
Nonalcoholic fatty liver disease assessed by multiple tools are correlated to periodontal conditions
10.1038/s41598-026-40128-y · ExternalCitation · doi-reference
Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease
10.1038/srep35282 · ExternalCitation · doi-reference
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor
10.1039/c8fo00107c · ExternalCitation · doi-reference
Role of TGR5 (GPBAR1) in liver disease
10.1055/s-0038-1669940 · ExternalCitation · doi-reference
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
10.1073/pnas.0511167103 · ExternalCitation · doi-reference
Reproducibility of a commercially available subgingival plaque sampling strategy and analysis strategy with oligonucleotide probes
10.1080/00016357.2017.1303192 · ExternalCitation · doi-reference
Progress in research on the roles of TGR5 receptor in liver diseases
10.1080/00365521.2021.1903547 · ExternalCitation · doi-reference
Innovative application of nested PCR for detection of Porphyromonas gingivalis in human highly calcified atherothrombotic plaques
10.1080/20002297.2020.1742523 · ExternalCitation · doi-reference
Galectin-12 modulates Kupffer cell polarization to alter the progression of nonalcoholic fatty liver disease
10.1093/glycob/cwad062 · ExternalCitation · doi-reference
Western diet-induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis
10.1096/fj.201902687r · ExternalCitation · doi-reference
From inflamed gums to infected heart: linking periodontal diseases and myocardial infarction
10.1097/crd.0000000000000898 · ExternalCitation · doi-reference
Periodontitis, coronary heart disease and myocardial infarction: treat one, benefit all
10.1097/mbc.0000000000000928 · ExternalCitation · doi-reference
Association between periodontitis and fibrotic progression of non-alcoholic fatty liver among Japanese adults
10.1111/jcpe.13415 · ExternalCitation · doi-reference
The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice
10.1111/jcpe.13682 · ExternalCitation · doi-reference
Porphyromonas gingivalis exacerbates alcoholic liver disease by altering gut microbiota composition and host immune response in mice
10.1111/jcpe.13833 · ExternalCitation · doi-reference
Gut-liver-axis: Barrier function of liver sinusoidal endothelial cell
10.1111/jgh.15512 · ExternalCitation · doi-reference
Porphyromonas gingivalis-induced production of reactive oxygen species, tumor necrosis factor-α, interleukin-6, CXCL8 and CCL2 by neutrophils from localized aggressive periodontitis and healthy donors: modulating actions of red blood cells and resolvin E1
10.1111/jre.12388 · ExternalCitation · doi-reference
Periodontitis is associated with incident chronic liver disease-a population-based cohort study
10.1111/liv.13985 · ExternalCitation · doi-reference
Fibrosis progression rate in a systematic review of placebo-treated nonalcoholic steatohepatitis
10.1111/liv.14749 · ExternalCitation · doi-reference
Porphyromonas gingivalis-derived lipopolysaccharide causes excessive hepatic lipid accumulation via activating NF-κB and JNK signaling pathways
10.1111/odi.13153 · ExternalCitation · doi-reference
The role of TLR4/MyD88/NF-κB pathway in periodontitis-induced liver inflammation of rats
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