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References from Perfluorooctanoic acid–associated complement factor B upregulation and atrial fibrillation–related molecular alterations: integrated network toxicology, Mendelian randomization, molecular dynamics, and HL-1 cell analyses. Local targets link to admitted publications; unresolved targets remain external evidence.
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
10.1039/d0em00291g · 2020 · External reference
Perfluorinated compounds: occurrence and uses in products
2011 · External reference
Research updates on the mechanism and influencing factors of the photocatalytic degradation of perfluorooctanoic acid (PFOA) in water environments
10.3390/molecules28114489 · 2023 · External reference
Microbial degradation of polyfluoroalkyl chemicals in the environment: a review
10.1016/j.envint.2013.08.022 · 2013 · External reference
The dilemma of perfluorooctanoate (PFOA) human half-life
10.1016/j.yrtph.2021.105025 · 2021 · External reference
Biomonitoring of perfluoroalkyl acids in human urine and estimates of biological half-life
10.1021/es401905e · 2013 · External reference
Metabolic syndrome and endocrine disrupting chemicals: an overview of exposure and health effects
10.3390/ijerph182413047 · 2021 · External reference
Differential toxicity between perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA)
10.2131/jts.41.s27 · 2016 · External reference
Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA)
10.1289/ehp.0901827 · 2010 · External reference
Perfluorooctanoic acid and cardiovascular disease in US adults
10.1001/archinternmed.2012.3393 · 2012 · External reference
Serum polyfluoroalkyl chemicals are associated with risk of cardiovascular diseases in national US population
10.1016/j.envint.2018.05.051 · 2018 · External reference
Research progress in current and emerging issues of PFASs' global impact: long-term health effects and governance of food systems
10.3390/foods14060958 · 2025 · External reference
The impact of PFAS on the public health and safety of future food supply in Europe: challenges and AI technologies solutions of environmental sustainability
10.20944/preprints202502.1091.v1 · External reference
Global epidemiology of atrial fibrillation: an increasing epidemic and public health challenge
10.1177/1747493019897870 · 2021 · External reference
Atrial fibrillation: the current epidemic
10.11909/j.issn.1671-5411.2017.03.011 · 2017 · External reference
The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms
10.1161/circresaha.114.303211 · 2014 · External reference
Atrial fibrillation: mechanisms, therapeutics, and future directions
10.1002/cphy.c140047 · 2015 · External reference
Inflammation and the pathogenesis of atrial fibrillation
10.1038/nrcardio.2015.2 · 2015 · External reference
Left atrial remodeling mechanisms associated with atrial fibrillation
10.1007/s13239-021-00527-w · 2019 · External reference
C-reactive protein, interleukin-6 and tumor necrosis factor alpha as predictors of incident coronary and cardiovascular events and total mortality
10.1160/th05-08-0571 · 2006 · External reference
Baseline and postoperative levels of C-reactive protein and interleukins as inflammatory predictors of atrial fibrillation following cardiac surgery: a systematic review and meta-analysis
10.5603/kp.a2017.0242 · 2018 · External reference
Inflammasome signaling in cardiac arrhythmias: linking inflammation, fibrosis, and electrical remodeling
10.3390/ijms26135954 · 2025 · External reference
Regulation and functions of NLRP3 inflammasome in cardiac fibrosis: current knowledge and clinical significance
10.1016/j.biopha.2021.112219 · 2021 · External reference
The alternative complement pathway revisited
10.1111/j.1582-4934.2008.00350.x · 2008 · External reference
The role of the alternative pathway of complement activation in glomerular diseases
10.1007/s10238-018-0491-8 · 2018 · External reference
Structures of C3b in complex with factors B and D give insight into complement convertase formation
10.1126/science.1195821 · 2010 · External reference
Factor B and C4b2a autoantibodies in C3 glomerulopathy
10.3389/fimmu.2019.00668 · 2019 · External reference
Toxicogenomics and systems toxicology: aims and prospects
10.1038/nrg1493 · 2004 · External reference
Functional genomics- and network-driven systems biology approaches for pharmacogenomics and toxicogenomics
10.2174/138920012802138633 · 2012 · External reference
Pubchem 2023 update
10.1093/nar/gkac956 · 2023 · External reference
Pubchem 2025 update
10.1093/nar/gkae1059 · 2025 · External reference
Pubchem's BioAssay database
10.1093/nar/gkr1132 · 2012 · External reference
The comparative toxicogenomics database: a cross-species resource for building chemical-gene interaction networks
10.1093/toxsci/kfl009 · 2006 · External reference
Comparative toxicogenomics database: a knowledgebase and discovery tool for chemical-gene-disease networks
10.1093/nar/gkn580 · 2009 · External reference
Comparative toxicogenomics database (CTD): update 2023
10.1093/nar/gkac833 · 2023 · External reference
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules
10.1093/nar/gkz382 · 2019 · External reference
A pathology atlas of the human cancer transcriptome
10.1126/science.aan2507 · 2017 · External reference
A gene-centric human protein atlas for expression profiles based on antibodies
10.1074/mcp.r800013-mcp200 · 2008 · External reference
Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2022
10.1093/nar/gkab951 · 2022 · External reference
Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2024
10.1093/nar/gkad1078 · 2024 · External reference
Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2025
10.1093/nar/gkae978 · 2025 · External reference
Role of inflammation in the pathogenesis of atrial fibrillation
10.3389/fphys.2022.862164 · 2022 · External reference
Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology
10.1038/s41569-022-00759-w · 2023 · External reference
Cytokines in inflammatory disease
10.3390/ijms20236008 · 2019 · External reference
The role of complement in inflammatory diseases from behind the scenes into the spotlight
10.2353/ajpath.2007.070190 · 2007 · External reference
The complement system and diabetic retinopathy
10.1016/j.survophthal.2024.02.004 · 2024 · External reference
A guide to complement biology, pathology and therapeutic opportunity
10.1038/s41577-023-00926-1 · 2024 · External reference
Mechanisms of myocardial reperfusion injury
10.1016/s0003-4975(99)01073-5 · 1999 · External reference
Complement in ischemia reperfusion injury
10.1016/s0002-9440(10)63830-8 · 2003 · External reference
Interactions between atrial fibrosis and inflammation in atrial fibrillation
10.3389/fcvm.2025.1578148 · 2025 · External reference
Atrial fibrillation after cardiac surgery/cardiopulmonary bypass is associated with monocyte activation
10.1213/01.ane.0000155260.93406.29 · 2005 · External reference
The role of adipose tissue M1/M2 macrophages in type 2 diabetes mellitus
10.1007/s13340-020-00482-2 · 2021 · External reference
Drug repurposing in cardiovascular inflammation: successes, failures, and future opportunities
10.3389/fphar.2022.1046406 · 2022 · External reference
