Research graph
References from PVN-centered multi-omics and single-cell analyses suggest shared inflammatory and immune features in acute myocardial infarction-associated ventricular arrhythmia and atrial fibrillation. Local targets link to admitted publications; unresolved targets remain external evidence.
The diagnosis and management of ventricular arrhythmias
10.1038/nrcardio.2011.15 · 2011 · External reference
The sympathetic nervous system and ventricular arrhythmias: an inseparable union
10.1093/eurheartj/ehab168 · 2021 · External reference
Acute myocardial infarction
10.1016/s0140-6736(16)30677-8 · 2017 · External reference
Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction
10.1371/journal.pone.0177750 · 2017 · External reference
Atrial fibrillation post-myocardial infarction: frequency, consequences, and management
10.1007/s11897-004-0002-y · 2004 · External reference
Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications
10.1093/eurheartj/ehn579 · 2009 · External reference
New atrial fibrillation after acute myocardial infarction independently predicts death: the GUSTO-III experience
10.1067/mhj.2000.111108 · 2000 · External reference
Microglia activation in the hypothalamic PVN following myocardial infarction
10.1016/j.brainres.2010.02.028 · 2010 · External reference
Myocardial inflammation predicts remodeling and neuroinflammation after myocardial infarction
10.1016/j.jacc.2017.11.024 · 2018 · External reference
Modulation of activated astrocytes in the hypothalamus paraventricular nucleus to prevent ventricular arrhythmia complicating acute myocardial infarction
10.1016/j.ijcard.2020.01.035 · 2020 · External reference
Microglial mincle receptor in the PVN contributes to sympathetic hyperactivity in acute myocardial infarction rat
10.1111/jcmm.13890 · 2019 · External reference
Cardiac sympathetic afferent ablation to prevent ventricular arrhythmia complicating acute myocardial infarction by inhibiting activated astrocytes
10.1111/jcmm.17508 · 2022 · External reference
Atrial fibrillation complicating acute myocardial infarction: prevalence, impact, and management considerations
10.1007/s11886-024-02040-7 · 2024 · External reference
Fir(e)ing the rhythm
10.1016/j.jacbts.2022.12.004 · 2023 · External reference
New biomarkers from multiomics approaches: improving risk prediction of atrial fibrillation
10.1093/cvr/cvab073 · 2021 · External reference
A murine model of myocardial ischemia-reperfusion injury through ligation of the left anterior descending artery
10.3791/51329 · 2014 · External reference
Isoflurane produces sustained cardiac protection after ischemia-reperfusion injury in mice
10.1097/00000542-200603000-00017 · 2006 · External reference
Bilirubin nanoparticles protect against cardiac ischemia/reperfusion injury in mice
10.1161/jaha.121.021212 · 2021 · External reference
Intraperitoneal bilirubin administration decreases infarct area in a rat coronary ischemia/reperfusion model
10.3389/fphys.2014.00053 · 2014 · External reference
Region-specific gene expression profiles in the left atria of patients with valvular atrial fibrillation
10.1016/j.hrthm.2012.11.013 · 2013 · External reference
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
10.1038/s41588-021-00913-z · 2021 · External reference
Left atrial single-cell transcriptomics reveals amphiregulin as a surrogate marker for atrial fibrillation
10.1038/s42003-024-07308-w · 2024 · External reference
Metaboanalyst 3.0–making metabolomics more meaningful
10.1093/nar/gkv380 · 2015 · External reference
Cytoscape: a software environment for integrated models of biomolecular interaction networks
10.1101/gr.1239303 · 2003 · External reference
The GTEx consortium atlas of genetic regulatory effects across human tissues
10.1126/science.aaz1776 · 2020 · External reference
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
10.1038/ng.3538 · 2016 · External reference
The MR-base platform supports systematic causal inference across the human phenome
10.7554/elife.34408 · 2018 · External reference
Bayesian Test for colocalisation between pairs of genetic association studies using summary statistics
10.1371/journal.pgen.1004383 · 2014 · External reference
Drugbank 5.0: a major update to the DrugBank database for 2018
10.1093/nar/gkx1037 · 2018 · External reference
Autodock vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
10.1002/jcc.21334 · 2010 · External reference
CB-Dock2: improved protein-ligand blind docking by integrating cavity detection, docking and homologous template fitting
10.1093/nar/gkac394 · 2022 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer
10.1016/j.immuni.2013.10.003 · 2013 · External reference
Effect of TLR4/MyD88/NF-kB axis in paraventricular nucleus on ventricular arrhythmias induced by sympathetic hyperexcitation in post-myocardial infarction rats
10.1111/jcmm.17309 · 2022 · External reference
Low-intensity focused ultrasound modulation of the paraventricular nucleus to prevent myocardial infarction-induced ventricular arrhythmia
10.1016/j.hrthm.2023.11.026 · 2024 · External reference
Microglia-Mediated neuroimmune response regulates cardiac remodeling after myocardial infarction
10.1161/jaha.122.029053 · 2023 · External reference
Immune remodeling and atrial fibrillation
10.3389/fphys.2022.927221 · 2022 · External reference
Ventricular arrhythmias and myocardial infarction: electrophysiological and neuroimmune mechanisms
10.3390/biomedicines13061290 · 2025 · External reference
Bile acids and bilirubin role in oxidative stress and inflammation in cardiovascular diseases
10.3390/diseases12050103 · 2024 · External reference
Role of bilirubin in the prognosis of coronary artery disease and its relationship with cardiovascular risk factors: a meta-analysis
10.1186/s12872-022-02899-w · 2022 · External reference
Association between inflammation and new-onset atrial fibrillation in acute coronary syndromes
10.3390/jcm13175088 · 2024 · External reference
The role of pro-inflammatory cytokines in the pathogenesis of cardiovascular disease
10.3390/ijms25021082 · 2024 · External reference
2022 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
10.1093/eurheartj/ehac262 · 2022 · External reference
2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation
10.1161/cir.0000000000001193 · 2024 · External reference
Multi-ethnic genome-wide association study for atrial fibrillation
10.1038/s41588-018-0133-9 · 2018 · External reference
Large-scale association analysis identifies new risk loci for coronary artery disease
10.1038/ng.2480 · 2013 · External reference
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
10.1038/s41588-022-01233-6 · 2022 · External reference
