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References from Curcumin as an adjunct in periodontal therapy: local effects, delivery systems, and clinical perspectives. Local targets link to admitted publications; unresolved targets remain external evidence.
Turmeric and curcumin: biological actions and medicinal applications
2004 · External reference
Zur kenntnis des curcumins
10.1002/cber.191004302168 · 1910 · External reference
Aromatische telluretin-verbindungen. I
10.1002/cber.19130460214 · 1913 · External reference
A chromatographic study of the curcuminoids in Curcuma longa L
10.1111/j.2042-7158.1953.tb14007.x · 1953 · External reference
Curcumin inhibits immunostimulatory function of dendritic cells: mAPKs and translocation of NF-kappa B as potential targets
10.4049/jimmunol.174.12.8116 · 2005 · External reference
Effects of curcumin on tumour necrosis factor-alpha and interleukin-6 in the late phase of experimental acute pancreatitis
10.1111/j.1439-0442.2006.00786.x · 2006 · External reference
Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model
10.1016/j.intimp.2010.02.011 · 2010 · External reference
Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-jun pathway
10.1254/jphs.09134fp · 2009 · External reference
Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research
2009 · External reference
Curcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytes
10.1007/s00011-009-0063-1 · 2009 · External reference
Enhancement of wound healing by curcumin in animals
10.1046/j.1524-475x.1998.60211.x · 1998 · External reference
A comprehensive review on the therapeutic potential of Curcuma longa linn. In relation to its Major active constituent curcumin
10.3389/fphar.2022.820806 · 2022 · External reference
The importance of Helicobacter pylori tnpA, tnpB, and cagA genes in Various gastrointestinal diseases
10.3103/s0891416817010049 · 2017 · External reference
The effects of curcumin on vascular endothelial function, lipid metabolism, inflammation and neuroprotection—a review
10.3390/nu18071032 · 2026 · External reference
Curcumin attenuated paracetamol overdose induced hepatitis
10.3748/wjg.v19.i12.1962 · 2013 · External reference
Therapeutic potential of green synthesized silver nanoparticles loaded PVA hydrogel patches for wound healing
10.1016/j.jddst.2019.101308 · 2019 · External reference
Safety and efficacy of nanocurcumin as add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a pilot randomized clinical trial
10.1007/s13311-018-0606-7 · 2018 · External reference
Curcumin as a complementary treatment in oncological therapy: a systematic review
10.1007/s00228-024-03764-9 · 2025 · External reference
Clinical trials on curcumin in relation to its bioavailability and effect on malignant diseases: critical analysis
10.1007/s00210-023-02825-7 · 2024 · External reference
Periodontitis in systemic rheumatic diseases
10.1038/nrrheum.2009.28 · 2009 · External reference
Dental caries and periodontal diseases in the ageing population: call to action to protect and enhance oral health and well-being as an essential component of healthy ageing-consensus report of group 4 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases
10.1111/jcpe.12681 · 2017 · External reference
European Workshop in periodontal health and cardiovascular disease-scientific evidence on the association between periodontal and cardiovascular diseases: a review of the literature
10.1093/eurheartj/suq003 · 2010 · External reference
Full-mouth ultrasonic debridement versus quadrant scaling and root planing as an initial approach in the treatment of chronic periodontitis
10.1111/j.1600-051x.2005.00776.x · 2005 · External reference
Systematic review and meta-analysis of randomized controlled trials evaluating the efficacy of non-surgical periodontal treatment in patients with concurrent systemic conditions
10.1007/s00784-023-05392-6 · 2024 · External reference
Treatment of peri-implantitis by the vector system
10.1111/j.1600-0501.2005.01141.x · 2005 · External reference
Strategies for implant surface decontamination in peri-implantitis therapy
2022 · External reference
Chlorhexidine compared with other locally delivered antimicrobials. A short review
10.1111/j.1600-051x.1986.tb01445.x · 1986 · External reference
Chlorhexidine and related compounds
10.1177/00220345890680s309 · 1989 · External reference
Antibacterial properties of hibitane
10.1111/j.1600-051x.1977.tb01888.x · 1977 · External reference
Side effects of chlorhexidine mouthwashes
10.1111/j.1600-0722.1971.tb02001.x · 1971 · External reference
Design and biological response of doxycycline loaded chitosan microparticles for periodontal disease treatment
10.1016/j.carbpol.2018.01.043 · 2018 · External reference
Tetracyclines
1973 · External reference
Minocycline: a review of its antibacterial and pharmacokinetic properties and therapeutic use
10.2165/00003495-197509040-00001 · 1975 · External reference
Susceptibility and resistance of plaque bacteria to minocycline
10.1902/jop.1990.61.4.228 · 1990 · External reference
Effects of doxycycline on clinical, microbiological and immunological parameters in well-controlled diabetes type 2 patients with periodontal disease: a randomized, controlled clinical trial
10.1111/jcpe.12287 · 2014 · External reference
Effects of periodontal therapy on metabolic control in patients with type 2 diabetes mellitus and periodontal disease: a meta-analysis
10.1097/md.0000000000000292 · 2014 · External reference
Metronidazole in periodontitis: reduced need for surgery
10.1111/j.1600-051x.1992.tb00442.x · 1992 · External reference
Periodontology: antibiotics protocol
10.1038/sj.bdj.2014.1041 · 2014 · External reference
Metronidazole enhances killing of Porphyromonas gingivalis by human PMNs
10.3389/froh.2022.933997 · 2022 · External reference
Microbiological changes associated with four different periodontal therapies for the treatment of chronic periodontitis
10.1111/j.1399-302x.2007.00403.x · 2008 · External reference
Treatment of oral malodor and periodontal disease using an antibiotic rinse
2013 · External reference
Systemic antibiotics in the treatment of periodontal disease
10.1034/j.1600-0757.2002.280107.x · 2002 · External reference
Antimicrobials in dentistry: with knowledge comes responsibility
10.1177/00220345960750070201 · 1996 · External reference
Effects of local and systemic metronidazole as adjunctive treatment in chronic periodontitis patients
10.1002/cre2.70050 · 2024 · External reference
Systematic review and meta-analysis on the nonsurgical treatment of chronic periodontitis by means of scaling and root planing with or without adjuncts
10.1016/j.adaj.2015.01.028 · 2015 · External reference
The laser gingivectomy. The use of the CO2 laser for the removal of phenytoin hyperplasia
10.1902/jop.1985.56.8.492 · 1985 · External reference
Uso do laser e suas implicações como alternativa terapêutica na periodontia e implantodontia
2015 · External reference
Evaluating the potency of laser-activated antimicrobial photodynamic therapy utilizing methylene blue as a treatment approach for chronic periodontitis
10.3389/froh.2024.1407201 · 2024 · External reference
Photodynamic therapy: a target therapy in periodontics
10.5005/jp-journals-10022-1051 · 2014 · External reference
Bactericidal effects of different laser systems on bacteria adhered to dental implant surfaces: an in vitro study comparing zirconia with titanium
10.1111/j.1600-0501.2009.01835.x · 2010 · External reference
Bactericidal effect of the er:yAG laser on dental implant surfaces: an in vitro study
10.1902/jop.2002.73.11.1292 · 2002 · External reference
Assessing health-related quality of life with antimicrobial photodynamic therapy (APDT) and low level laser therapy (LLLT) after third molar removal
2013 · External reference
Efficacy of photodynamic therapy and lasers as an adjunct to scaling and root planing in the treatment of aggressive periodontitis: a clinical and microbiologic short-term study
10.7860/jcdr/2016/17733.7490 · 2016 · External reference
Clinical and microbiological effects of photodynamic therapy associated with non-surgical treatment in aggressive periodontitis
10.5681/joddd.2014.028 · 2014 · External reference
Antimicrobial photodynamic therapy as an adjunct to non-surgical treatment of aggressive periodontitis: a split-mouth randomized controlled trial
10.1902/jop.2015.140504 · 2015 · External reference
Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: microbiological profile
10.1007/s10103-010-0854-7 · 2012 · External reference
The functional genomic studies of curcumin
10.1016/j.semcancer.2017.04.002 · 2017 · External reference
Highly bioavailable forms of curcumin and promising avenues for curcumin-based research and application: a review
10.3390/molecules25061397 · 2020 · External reference
Inflammatory mediators in the pathogenesis of periodontitis
10.1017/erm.2013.8 · 2013 · External reference
Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes
10.1196/annals.1329.067 · 2004 · External reference
An in vitro evaluation of antibacterial activity of curcumin against common endodontic bacteria
10.7324/japs.2013.31018 · 2013 · External reference
Curcumin as a promising antibacterial agent: effects on metabolism and biofilm formation in S. mutans
10.1155/2018/4508709 · 2018 · External reference
Effect of curcumin on growth, biofilm formation and virulence factor gene expression of Porphyromonas gingivalis
10.1007/s10266-020-00514-y · 2021 · External reference
In vitro antimicrobial effect of curcumin-based photodynamic therapy on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans
10.1016/j.pdpdt.2020.102055 · 2020 · External reference
Antimicrobial photodynamic therapy in dentistry using an oil-in-water microemulsion with curcumin as a mouthwash
10.1016/j.pdpdt.2020.101962 · 2020 · External reference
Adjuvant effects of curcumin as a photoantimicrobial or irrigant in the non-surgical treatment of periodontitis: systematic review and meta-analysis
10.1016/j.pdpdt.2021.102265 · 2021 · External reference
Local administration of curcumin-loaded nanoparticles effectively inhibits inflammation and bone resorption associated with experimental periodontal disease
10.1038/s41598-018-24866-2 · 2018 · External reference
Antibacterial mechanism of curcumin: a review
10.1002/cbdv.202000171 · 2020 · External reference
Effect of curcumin on systemic T helper 17 cell response, gingival expressions of interleukin-17 and retinoic acid receptor-related orphan receptor γt, and alveolar bone loss in experimental periodontitis
10.1902/jop.2016.150722 · 2016 · External reference
Systemic treatment with resveratrol and/or curcumin reduces the progression of experimental periodontitis in rats
10.1111/jre.12382 · 2017 · External reference
Curcumin ameliorates alveolar bone destruction of experimental periodontitis by modulating osteoclast differentiation, activation and function
10.1016/j.jff.2016.01.025 · 2016 · External reference
Differential effects of natural curcumin and chemically modified curcumin on inflammation and bone resorption in model of experimental periodontitis
10.1016/j.archoralbio.2018.04.007 · 2018 · External reference
Dose-response assessment of chemically modified curcumin in experimental periodontitis
10.1002/jper.18-0392 · 2019 · External reference
A novel chemically modified curcumin reduces inflammation-mediated connective tissue breakdown in a rat model of diabetes: periodontal and systemic effects
10.1111/jre.12381 · 2017 · External reference
A chemically modified curcumin (CMC 2.24) inhibits nuclear factor κB activation and inflammatory bone loss in murine models of LPS-induced experimental periodontitis and diabetes-associated natural periodontitis
10.1007/s10753-017-0587-4 · 2017 · External reference
Enhanced efficacy of chemically modified curcumin in experimental periodontitis: systemic implications
10.2147/jep.s171119 · 2019 · External reference
Bioavailability of curcumin: problems and promises
10.1021/mp700113r · 2007 · External reference
Pharmacokinetics and pharmacodynamics of curcumin
10.1007/978-0-387-46401-5_20 · 2007 · External reference
Biotransformation of curcumin through reduction and glucuronidation in mice
10.1016/s0090-9556(24)15211-7 · 1999 · External reference
Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine
2002 · External reference
Occurrence of orally administered curcuminoid as glucuronide and sulfate conjugates in rat plasma
10.1016/s0024-3205(00)00868-7 · 2000 · External reference
Curcumin: a review of its effects on human health
10.3390/foods6100092 · 2017 · External reference
The essential medicinal chemistry of curcumin
10.1021/acs.jmedchem.6b00975 · 2017 · External reference
Evaluation of local drug delivery system containing 2% whole turmeric gel used as an adjunct to scaling and root planing in chronic periodontitis: a clinical and microbiological study
10.4103/0972-124x.79995 · 2011 · External reference
Effectiveness of curcumin gel as local drug delivery agent in the treatment of chronic periodontitis: a clinical study
10.7860/jcdr/2015/13497.6550 · 2015 · External reference
Comparative evaluation of turmeric and chlorhexidine gluconate mouthwash in prevention of plaque formation and gingivitis: a clinical and microbiological study
10.5005/jp-journals-10024-1038 · 2011 · External reference
Effects of curcumin on oral health: a systematic review
10.7860/jcdr/2015/15481.6565 · 2015 · External reference
Comparative evaluation of curcumin and chlorhexidine irrigation in periodontal therapy: a clinical study
10.4103/0972-124x.145791 · 2015 · External reference
Use of curcumin as a local drug delivery agent in periodontitis: a systematic review
10.4103/jisp.jisp_309_16 · 2017 · External reference
Effects of photodynamic therapy with curcumin on periodontal pathogens: a clinical study
10.1016/j.pdpdt.2014.05.001 · 2014 · External reference
Effect of adjunctive photodynamic therapy with curcumin on periodontal parameters: randomized clinical trial
10.1007/s10103-014-1685-8 · 2015 · External reference
Local administration of nanocurcumin reduces inflammation and bone loss in experimental periodontitis
10.1111/jre.12589 · 2019 · External reference
Safety and anti-inflammatory activity of curcumin: a component of turmeric (Curcuma longa)
10.1089/107555303321223035 · 2003 · External reference
Curcumin-incorporated biomaterials for tissue regeneration: a review
10.1016/j.msec.2018.11.083 · 2019 · External reference
Development of satranidazole and curcumin-loaded biodegradable films for periodontal therapy
10.3109/10717544.2013.860521 · 2014 · External reference
Curcumin nanoformulations: a future nanomedicine for cancer
10.1016/j.drudis.2011.09.009 · 2012 · External reference
Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine
10.1016/j.ejps.2009.02.019 · 2009 · External reference
Curcumin delivery mediated by bio-based nanoparticles: a review
10.3390/molecules25030689 · 2020 · External reference
Advances in nanotechnology-based delivery systems for curcumin
10.2217/nnm.12.80 · 2012 · External reference
Curcumin and curcumin-loaded nanoparticles: anticancer and antimicrobial effects
10.1016/j.biotechadv.2015.05.009 · 2015 · External reference
Therapeutic roles of curcumin: lessons learned from clinical trials
10.1208/s12248-012-9432-8 · 2013 · External reference
Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets
10.1016/j.tips.2008.11.002 · 2009 · External reference
Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
10.1111/bph.13621 · 2017 · External reference
Curcumin, a component of golden spice: from bedside to bench and back
10.1016/j.biotechadv.2014.04.004 · 2014 · External reference