Research graph
References from Case Report: Tislelizumab-associated secondary adrenal insufficiency in a patient with lung squamous cell carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Aptamers as immune checkpoint inhibitors in cancer immunotherapy: Targeting Ctla-4/B7 and Pd-1/Pd-L1 pathways
10.1016/j.intimp.2025.115339 · 2025 · External reference
Cancer immunotherapy using checkpoint blockade
10.1126/science.aar4060 · 2018 · External reference
Immune-related adverse events associated with immune checkpoint inhibitors: A scoping review
10.3390/ph19020276 · 2026 · External reference
Endocrinopathies associated with immune checkpoint inhibitor use
10.1016/j.eprac.2024.03.023 · 2024 · External reference
Initial symptoms and diagnostic delay in immune checkpoint inhibitor-related adrenal insufficiency: A systematic review and meta-ethnography of case reports
10.3389/fendo.2025.1636452 · 2025 · External reference
Tislelizumab: first approval
10.1007/s40265-020-01286-z · 2020 · External reference
Adrenal insufficiency in adults: A review
10.1001/jama.2025.5485 · 2025 · External reference
A method for estimating the probability of adverse drug reactions
10.1038/clpt.1981.154 · 1981 · External reference
Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: An Ese clinical practice guideline
10.1530/eje-22-0689 · 2022 · External reference
Adrenal insufficiency
10.1016/s0140-6736(21)00136-7 · 2021 · External reference
Hypophysitis and secondary adrenal insufficiency from immune checkpoint inhibitors: Diagnostic challenges and link with survival
10.6004/jnccn.2022.7098 · 2023 · External reference
Pituitary expression of Ctla-4 mediates hypophysitis secondary to administration of Ctla-4 blocking antibody
10.1126/scitranslmed.3008002 · 2014 · External reference
Hypophysitis secondary to nivolumab and pembrolizumab is a clinical entity distinct from ipilimumab-associated hypophysitis
10.1530/eje-19-0238 · 2019 · External reference
Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors
10.1136/jitc-2021-002493 · 2021 · External reference
Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities
10.1073/pnas.1908079116 · 2019 · External reference
Paraneoplastic isolated adrenocorticotropic hormone deficiency revealed after immune checkpoint inhibitors therapy: New insights into anti-corticotroph antibody
10.3389/fimmu.2023.1284301 · 2023 · External reference
Adrenal crisis mainly manifested as recurrent syncope secondary to tislelizumab: A case report and literature review
10.3389/fimmu.2023.1295310 · 2024 · External reference
Immunotherapy-induced hypophysitis following treatment with tislelizumab in an elderly patient with bladder cancer and prostate cancer: A case report
10.7759/cureus.51015 · 2023 · External reference
Immune checkpoint inhibitor-related adrenal hypofunction and psoriasisby induced by tislelizumab: A case report and review of literature
10.1097/md.0000000000037562 · 2024 · External reference
Case report: Robust and durable response to the combination of tislelizumab and chemotherapy in advanced thymic epithelial tumors: A case series
10.3389/fimmu.2025.1516297 · 2025 · External reference
Hypophysitis induced by tislelizumab: A case report of somnolence and delirium with elevated eosinophils
10.12659/ajcr.948143 · 2025 · External reference
Prolonged progression-free survival in a patient with highly pretreated recurrent ovarian cancer after developing multisystem immune-related adverse events: A case report and literature review
10.1159/000546423 · 2025 · External reference
Multiple endocrine adverse reactions and pituitary axis dysfunction induced by Pd-1 immunotherapy in an esophageal cancer patient: Case report
10.1097/md.0000000000048449 · 2026 · External reference
Pituitary-adrenal axis dysfunction induced by tislelizumab immunotherapy for non-small cell lung cancer: A case series and literature review
10.1186/s12890-024-03140-4 · 2024 · External reference
Adrenal insufficiency development during chemotherapy plus anti-programmed death receptor-1 monoclonal antibody (Tislelizumab) therapy in patients with advanced gastric cancer: Two case reports
10.12701/yujm.2021.00934 · 2022 · External reference
Adrenal insufficiency in adults: A review
10.1001/jama.2025.5485 · ExternalCitation · doi-reference
Tislelizumab: first approval
10.1007/s40265-020-01286-z · ExternalCitation · doi-reference
Endocrinopathies associated with immune checkpoint inhibitor use
10.1016/j.eprac.2024.03.023 · ExternalCitation · doi-reference
Aptamers as immune checkpoint inhibitors in cancer immunotherapy: Targeting Ctla-4/B7 and Pd-1/Pd-L1 pathways
10.1016/j.intimp.2025.115339 · ExternalCitation · doi-reference
Adrenal insufficiency
10.1016/s0140-6736(21)00136-7 · ExternalCitation · doi-reference
A method for estimating the probability of adverse drug reactions
10.1038/clpt.1981.154 · ExternalCitation · doi-reference
Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities
10.1073/pnas.1908079116 · ExternalCitation · doi-reference
Immune checkpoint inhibitor-related adrenal hypofunction and psoriasisby induced by tislelizumab: A case report and review of literature
10.1097/md.0000000000037562 · ExternalCitation · doi-reference
Multiple endocrine adverse reactions and pituitary axis dysfunction induced by Pd-1 immunotherapy in an esophageal cancer patient: Case report
10.1097/md.0000000000048449 · ExternalCitation · doi-reference
Cancer immunotherapy using checkpoint blockade
10.1126/science.aar4060 · ExternalCitation · doi-reference
Pituitary expression of Ctla-4 mediates hypophysitis secondary to administration of Ctla-4 blocking antibody
10.1126/scitranslmed.3008002 · ExternalCitation · doi-reference
Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors
10.1136/jitc-2021-002493 · ExternalCitation · doi-reference
Prolonged progression-free survival in a patient with highly pretreated recurrent ovarian cancer after developing multisystem immune-related adverse events: A case report and literature review
10.1159/000546423 · ExternalCitation · doi-reference
Pituitary-adrenal axis dysfunction induced by tislelizumab immunotherapy for non-small cell lung cancer: A case series and literature review
10.1186/s12890-024-03140-4 · ExternalCitation · doi-reference
Hypophysitis induced by tislelizumab: A case report of somnolence and delirium with elevated eosinophils
10.12659/ajcr.948143 · ExternalCitation · doi-reference
Adrenal insufficiency development during chemotherapy plus anti-programmed death receptor-1 monoclonal antibody (Tislelizumab) therapy in patients with advanced gastric cancer: Two case reports
10.12701/yujm.2021.00934 · ExternalCitation · doi-reference
Hypophysitis secondary to nivolumab and pembrolizumab is a clinical entity distinct from ipilimumab-associated hypophysitis
10.1530/eje-19-0238 · ExternalCitation · doi-reference
Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: An Ese clinical practice guideline
10.1530/eje-22-0689 · ExternalCitation · doi-reference
Initial symptoms and diagnostic delay in immune checkpoint inhibitor-related adrenal insufficiency: A systematic review and meta-ethnography of case reports
10.3389/fendo.2025.1636452 · ExternalCitation · doi-reference
Paraneoplastic isolated adrenocorticotropic hormone deficiency revealed after immune checkpoint inhibitors therapy: New insights into anti-corticotroph antibody
10.3389/fimmu.2023.1284301 · ExternalCitation · doi-reference
Adrenal crisis mainly manifested as recurrent syncope secondary to tislelizumab: A case report and literature review
10.3389/fimmu.2023.1295310 · ExternalCitation · doi-reference
Case report: Robust and durable response to the combination of tislelizumab and chemotherapy in advanced thymic epithelial tumors: A case series
10.3389/fimmu.2025.1516297 · ExternalCitation · doi-reference
Immune-related adverse events associated with immune checkpoint inhibitors: A scoping review
10.3390/ph19020276 · ExternalCitation · doi-reference
Hypophysitis and secondary adrenal insufficiency from immune checkpoint inhibitors: Diagnostic challenges and link with survival
10.6004/jnccn.2022.7098 · ExternalCitation · doi-reference
Immunotherapy-induced hypophysitis following treatment with tislelizumab in an elderly patient with bladder cancer and prostate cancer: A case report
10.7759/cureus.51015 · ExternalCitation · doi-reference