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References from Single-cell transcriptomic analysis reveals fatty acid metabolic heterogeneity and identifies DKK1 as a candidate prognostic factor in osteosarcoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Single-cell rna landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
10.1038/s41467-020-20059-6 · 2020 · External reference
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10.1016/j.cell.2019.05.031 · 2019 · External reference
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Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · 2021 · External reference
Gsva: gene set variation analysis for microarray and rna-seq data
10.1186/1471-2105-14-7 · 2013 · External reference
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10.1073/pnas.0506580102 · 2005 · External reference
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10.1016/j.cels.2015.12.004 · 2015 · External reference
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10.1093/nar/28.1.27 · 2000 · External reference
Reversed graph embedding resolves complex single-cell trajectories
10.1038/nmeth.4402 · 2017 · External reference
Improved reconstruction of single-cell developmental potential with cytotrace 2
10.1038/s41592-025-02857-2 · 2025 · External reference
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
10.1038/nbt.2859 · 2014 · External reference
Inference and analysis of cell-cell communication using cellchat
10.1038/s41467-021-21246-9 · 2021 · External reference
Determining cell type abundance and expression from bulk tissues with digital cytometry
10.1038/s41587-019-0114-2 · 2019 · External reference
Robust enumeration of cell subsets from tissue expression profiles
10.1038/nmeth.3337 · 2015 · External reference
Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
10.1006/meth.2001.1262 · 2001 · External reference
Understanding osteosarcomas
10.1097/01.jaa.0000541477.24116.8d · 2018 · External reference
The role of chemotherapy for metastatic, relapsed and refractory osteosarcoma
10.1007/s40272-014-0095-z · 2014 · External reference
Systematic rna interference reveals that oncogenic kras-driven cancers require tbk1
10.1038/nature08460 · 2009 · External reference
Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and t lymphocytes
10.1111/imm.12777 · 2017 · External reference
A-linolenic acid suppresses proliferation and invasion in osteosarcoma cells via inhibiting fatty acid synthase
10.3390/molecules27092741 · 2022 · External reference
Comprehensive analysis of fatty acid and lactate metabolism-related genes for prognosis value, immune infiltration, and therapy in osteosarcoma patients
10.3389/fonc.2022.934080 · 2022 · External reference
Tumor-associated macrophages in osteosarcoma
10.1631/jzus.b2100029 · 2021 · External reference
Metabolism in tumor-associated macrophages
10.1016/bs.ircmb.2022.01.004 · 2022 · External reference
Tumor-associated macrophages in osteosarcoma: from mechanisms to therapy
10.3390/ijms21155207 · 2020 · External reference
Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: from molecular mechanisms to potential targets
10.1016/j.jbo.2025.100660 · 2025 · External reference
Impact of lipid metabolism on macrophage polarization: implications for inflammation and tumor immunity
10.3390/ijms241512032 · 2023 · External reference
Ripk3 orchestrates fatty acid metabolism in tumor-associated macrophages and hepatocarcinogenesis
10.1158/2326-6066.cir-19-0261 · 2020 · External reference
Identification of m2 macrophage markers for predicting outcome and therapeutic response in osteosarcoma: integrated analysis of single-cell and bulk rna-sequencing
10.7150/jca.104855 · 2025 · External reference
Single-cell transcriptomics reveals the complexity of the tumor microenvironment of treatment-naive osteosarcoma
10.3389/fonc.2021.709210 · 2021 · External reference
Single-cell rna sequencing reveals the communications between tumor microenvironment components and tumor metastasis in osteosarcoma
10.3389/fimmu.2024.1445555 · 2024 · External reference
Antisense mediated blockade of dickkopf 1 attenuates tumor survival, metastases and bone damage in experimental osteosarcoma
10.1038/s41598-024-84037-4 · 2025 · External reference
A single-cell and spatially resolved atlas of human osteosarcomas
10.1186/s13045-024-01598-7 · 2024 · External reference
Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
10.18632/oncotarget.13055 · 2016 · External reference
Survival after recurrent osteosarcoma: data from 3 european osteosarcoma intergroup (eoi) randomized controlled trials
10.1016/j.ejca.2010.11.036 · 2011 · External reference
Lenvatinib plus ifosfamide and etoposide in children and young adults with relapsed osteosarcoma: a phase 2 randomized clinical trial
10.1001/jamaoncol.2024.4381 · 2024 · External reference
Lipid metabolism in cancer progression and therapeutic strategies
10.1002/mco2.27 · 2021 · External reference
