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References from Breaching the Weismann barrier – a role of vitellogenin yolk proteins in nematode non-Mendelian inheritance. Local targets link to admitted publications; unresolved targets remain external evidence.
Bacterial vitamin B12 production enhances nematode predatory behavior
10.1038/s41396-020-0626-2 · 2020 · External reference
Culture-based analysis of Pristionchus-associated microbiota from beetles and figs for studying nematode-bacterial interactions
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Independent validation of transgenerational inheritance of learned pathogen avoidance in Caenorhabditis elegans
10.7554/elife.107034.1 · 2025 · External reference
The molecular and structural characterization of two vitellogenins from the free-living nematode Oscheius tipulae
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Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny
10.1038/s41594-026-01816-5 · 2026 · External reference
Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor
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Beyond the connectome: how neuromodulators shape neural circuits
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Co-option of the hormone-signalling module dafachronic acid-DAF-12 in nematode evolution
10.1038/nature09164 · 2010 · External reference
Vitamin B12 deficiency in Caenorhabditis elegans results in loss of fertility, extended life cycle, and reduced lifespan
10.1016/j.fob.2013.01.008 · 2013 · External reference
What is lost in the weismann barrier
10.3390/jdb8040035 · 2020 · External reference
Cloning of a yolk protein gene family from Caenorhabditis elegans
10.1016/0022-2836(84)90361-9 · 1984 · External reference
The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster
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Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
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The evolution of egg yolk proteins
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A Mediator subunit imparts robustness to a polyphenism decision
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Extensive sequence conservation among insect, nematode, and vertebrate vitellogenins reveals ancient common ancestry
10.1007/pl00006164 · 1997 · External reference
Plant and animal small RNA communications between cells and organisms
10.1038/s41580-021-00425-y · 2022 · External reference
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Experimental and theoretical support for costs of plasticity and phenotype in a nematode cannibalistic trait
10.1093/evlett/qrac001 · 2023 · External reference
Mating can initiate stable RNA silencing that overcomes epigenetic recovery
10.1038/s41467-021-24053-4 · 2021 · External reference
Double-stranded RNA made in C. elegans neurons can enter the germline and cause transgenerational gene silencing
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A differential dosage hypothesis for parental effects in seed development
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CEH-60/PBX and UNC-62/MEIS coordinate a metabolic switch that supports reproduction in C. elegans
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ADR-2 regulates fertility and oocyte fate in Caenorhabditis elegans
10.1093/genetics/iyae114 · 2024 · External reference
Predatory aggression evolved through adaptations to noradrenergic circuits
10.1038/s41586-025-10009-x · 2026 · External reference
C. elegans eats its own intestine to make yolk leading to multiple senescent pathologies
10.1016/j.cub.2018.10.003 · 2018 · External reference
The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation
10.1038/s41586-026-10232-0 · 2026 · External reference
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
10.1038/35888 · 1998 · External reference
Vitellogenins increase stress resistance of Caenorhabditis elegans after Photorhabdus luminescens infection depending on the steroid-signaling pathway
10.1016/j.micinf.2013.05.002 · 2013 · External reference
Molecular mechanisms of transgenerational epigenetic inheritance
10.1038/s41576-021-00438-5 · 2022 · External reference
Small RNAs and chromatin in the multigenerational epigenetic landscape of Caenorhabditis elegans
10.1098/rstb.2020.0112 · 2021 · External reference
Reported transgenerational responses to Pseudomonas aeruginosa in Caenorhabditis elegans are not robust
10.7554/elife.100254 · 2025 · External reference
Differential DNA methylation in discrete developmental stages of the parasitic nematode Trichinella spiralis
10.1186/gb-2012-13-10-r100 · 2012 · External reference
Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness
10.26508/lsa.202201675 · 2023 · External reference
The hunger strikes back: an epigenetic memory for autophagy
10.1038/s41418-023-01159-4 · 2023 · External reference
A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-β/Sma/Mab pathway
10.1016/j.ydbio.2016.02.031 · 2016 · External reference
Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte
10.1091/mbc.10.12.4311 · 1999 · External reference
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
10.1038/nature10572 · 2011 · External reference
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A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming
10.1126/science.abc9546 · 2020 · External reference
Nematodes of the genus Pristionchus are closely associated with scarab beetles and the Colorado potato beetle in Western Europe
10.1016/j.zool.2006.03.001 · 2006 · External reference
Development of the reproductive system of Caenorhabditis elegans
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10.1016/j.cell.2020.07.022 · 2020 · External reference
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10.1534/genetics.115.178699 · 2015 · External reference
Insulin/IGF signaling and vitellogenin provisioning mediate intergenerational adaptation to nutrient stress
10.1016/j.cub.2019.05.062 · 2019 · External reference
C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance
10.1038/s41586-020-2699-5 · 2020 · External reference
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10.1016/0012-1606(83)90322-6 · 1983 · External reference
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10.1126/science.aah6412 · 2017 · External reference
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10.1098/rspb.2018.2754 · 2019 · External reference
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10.1126/sciadv.adw9964 · 2025 · External reference
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10.1038/nature25012 · 2017 · External reference
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10.1101/gad.293504 · 2004 · External reference
Phylogenomic insights into the evolution and origin of Nematoda
10.1093/sysbio/syae073 · 2025 · External reference
Intraguild predation between Pristionchus pacificus and Caenorhabditis elegans: a complex interaction with the potential for aggressive behaviour
10.1080/01677063.2020.1833004 · 2020 · External reference
EBAX-1/ZSWIM8 destabilizes miRNAs resulting in transgenerational memory of a predatory trait
10.1126/sciadv.adu0875 · 2025 · External reference
Vitamin B12 induces memory of predation through vitellogenin provisioning
10.1038/s41467-026-71494-w · 2026 · External reference
A developmental switch coupled to the evolution of plasticity acts through a sulfatase
10.1016/j.cell.2013.09.054 · 2013 · External reference
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10.1016/b0-44-451924-6/00040-5 · 2005 · External reference
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Cleavage of two yolk proteins from a precursor in Caenorhabditis elegans
10.1016/0022-2836(84)90329-2 · 1984 · External reference
Two distinct yolk lipoprotein complexes from Caenorhabditis elegans
10.1016/s0021-9258(18)77319-5 · 1990 · External reference
Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum
10.1074/jbc.m111.269845 · 2011 · External reference
The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation
10.1126/science.abc9359 · 2020 · External reference
Mating induces shrinking and death in Caenorhabditis mothers
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Mating and male pheromone kill Caenorhabditis males through distinct mechanisms
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Production of YP170 vitellogenins promotes intestinal senescence in Caenorhabditis elegans
10.1093/gerona/glz067 · 2019 · External reference
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10.1093/nar/13.14.5283 · 1985 · External reference
Vitellogenin motifs conserved in nematodes and vertebrates
10.1007/bf02101283 · 1991 · External reference
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10.1126/science.282.5388.430 · 1998 · External reference
Vitellogenin accumulation leads to reproductive senescence by impairing lysosomal function
10.1007/s11427-022-2242-8 · 2023 · External reference
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10.1038/s41596-020-0347-z · 2020 · External reference
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Endomitosis controls tissue-specific gene expression during development
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New genetic regulators question relevance of abundant yolk protein production in C. Elegans
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Long-term gene silencing by RNAi
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Transgenerational effects of prenatal exposure to the 1944–45 Dutch famine
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SID-1 functions in multiple roles to support parental RNAi in Caenorhabditis elegans
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Unresolved reference
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Functional divergence of conserved developmental plasticity genes between two distantly related nematodes
10.1038/s41598-025-14207-5 · 2025 · External reference
An intergenerational lipid memory of the social environment in C. elegans
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Lysosomal control of proteostasis and reproductive capacity by conserved LMD-3 protein in C. elegans
10.1126/sciadv.adz3192 · 2025 · External reference
Fusion and expansion of vitellogenin vesicles during Caenorhabditis elegans intestinal senescence
10.1111/acel.13719 · 2022 · External reference
Beyond the connectome: how neuromodulators shape neural circuits
10.1002/bies.201100185 · ExternalCitation · doi-reference
The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster
10.1002/bies.950161009 · ExternalCitation · doi-reference
Weismann and evolution
10.1007/bf00138928 · ExternalCitation · doi-reference
Vitellogenin motifs conserved in nematodes and vertebrates
10.1007/bf02101283 · ExternalCitation · doi-reference
Extensive sequence conservation among insect, nematode, and vertebrate vitellogenins reveals ancient common ancestry
10.1007/pl00006164 · ExternalCitation · doi-reference
Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor
10.1007/pl00006528 · ExternalCitation · doi-reference
Vitellogenin accumulation leads to reproductive senescence by impairing lysosomal function
10.1007/s11427-022-2242-8 · ExternalCitation · doi-reference
Development of the reproductive system of Caenorhabditis elegans
10.1016/0012-1606(76)90267-0 · ExternalCitation · doi-reference
Yolk proteins of Caenorhabditis elegans
10.1016/0012-1606(83)90321-4 · ExternalCitation · doi-reference
Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans
10.1016/0012-1606(83)90322-6 · ExternalCitation · doi-reference
Vitellogenin gene of the silkworm, Bombyx mori: Structure and sex-dependent expression
10.1016/0014-5793(94)01265-2 · ExternalCitation · doi-reference
Cleavage of two yolk proteins from a precursor in Caenorhabditis elegans
10.1016/0022-2836(84)90329-2 · ExternalCitation · doi-reference
Cloning of a yolk protein gene family from Caenorhabditis elegans
10.1016/0022-2836(84)90361-9 · ExternalCitation · doi-reference
The evolution of egg yolk proteins
10.1016/0079-6107(89)90005-9 · ExternalCitation · doi-reference
3.9 Hormonal control of reproductive processes
10.1016/b0-44-451924-6/00040-5 · ExternalCitation · doi-reference
Origins and mechanisms of miRNAs and siRNAs
10.1016/j.cell.2009.01.035 · ExternalCitation · doi-reference
A developmental switch coupled to the evolution of plasticity acts through a sulfatase
10.1016/j.cell.2013.09.054 · ExternalCitation · doi-reference
Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits
10.1016/j.cell.2014.01.047 · ExternalCitation · doi-reference
Starvation-induced transgenerational inheritance of small RNAs in C. elegans
10.1016/j.cell.2014.06.020 · ExternalCitation · doi-reference
Piwi/PRG-1 Argonaute and TGF-β mediate transgenerational learned pathogenic avoidance
10.1016/j.cell.2019.05.024 · ExternalCitation · doi-reference
Three rules explain transgenerational small RNA inheritance in C. elegans
10.1016/j.cell.2020.07.022 · ExternalCitation · doi-reference
Intestine-to-germline transmission of epigenetic information intergenerationally ensures systemic stress resistance in C. elegans
10.1016/j.celrep.2020.02.050 · ExternalCitation · doi-reference
Stable inheritance of an acquired behavior in caenorhabditis elegans
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C. elegans eats its own intestine to make yolk leading to multiple senescent pathologies
10.1016/j.cub.2018.10.003 · ExternalCitation · doi-reference
Insulin/IGF signaling and vitellogenin provisioning mediate intergenerational adaptation to nutrient stress
10.1016/j.cub.2019.05.062 · ExternalCitation · doi-reference
CEH-60/PBX and UNC-62/MEIS coordinate a metabolic switch that supports reproduction in C. elegans
10.1016/j.devcel.2019.03.002 · ExternalCitation · doi-reference
Vitamin B12 deficiency in Caenorhabditis elegans results in loss of fertility, extended life cycle, and reduced lifespan
10.1016/j.fob.2013.01.008 · ExternalCitation · doi-reference
Mechanisms of transgenerational epigenetic inheritance: lessons from animal model organisms
10.1016/j.gde.2023.102024 · ExternalCitation · doi-reference
Molecular characteristics of insect vitellogenins
10.1016/j.jinsphys.2008.08.007 · ExternalCitation · doi-reference
Pristionchus – Beetle associations: Towards a new natural history
10.1016/j.jip.2024.108243 · ExternalCitation · doi-reference
Vitellogenins increase stress resistance of Caenorhabditis elegans after Photorhabdus luminescens infection depending on the steroid-signaling pathway
10.1016/j.micinf.2013.05.002 · ExternalCitation · doi-reference
A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-β/Sma/Mab pathway
10.1016/j.ydbio.2016.02.031 · ExternalCitation · doi-reference
Nematodes of the genus Pristionchus are closely associated with scarab beetles and the Colorado potato beetle in Western Europe
10.1016/j.zool.2006.03.001 · ExternalCitation · doi-reference
Two distinct yolk lipoprotein complexes from Caenorhabditis elegans
10.1016/s0021-9258(18)77319-5 · ExternalCitation · doi-reference
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
10.1016/s0092-8674(00)80620-0 · ExternalCitation · doi-reference
Specific interference by ingested dsRNA
10.1038/27579 · ExternalCitation · doi-reference
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
10.1038/35888 · ExternalCitation · doi-reference
Long-term gene silencing by RNAi
10.1038/442882b · ExternalCitation · doi-reference
Co-option of the hormone-signalling module dafachronic acid-DAF-12 in nematode evolution
10.1038/nature09164 · ExternalCitation · doi-reference
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
10.1038/nature10572 · ExternalCitation · doi-reference
Maternal age generates phenotypic variation in Caenorhabditis elegans
10.1038/nature25012 · ExternalCitation · doi-reference
Bacterial vitamin B12 production enhances nematode predatory behavior
10.1038/s41396-020-0626-2 · ExternalCitation · doi-reference
The hunger strikes back: an epigenetic memory for autophagy
10.1038/s41418-023-01159-4 · ExternalCitation · doi-reference
Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
10.1038/s41467-020-15555-8 · ExternalCitation · doi-reference
Mating can initiate stable RNA silencing that overcomes epigenetic recovery
10.1038/s41467-021-24053-4 · ExternalCitation · doi-reference
A histone demethylase links the loss of plasticity to nongenetic inheritance and morphological change
10.1038/s41467-023-44306-8 · ExternalCitation · doi-reference
Vitamin B12 induces memory of predation through vitellogenin provisioning
10.1038/s41467-026-71494-w · ExternalCitation · doi-reference
Intergenerational and transgenerational epigenetic inheritance in animals
10.1038/s41556-018-0242-9 · ExternalCitation · doi-reference
Soma-to-germline RNA communication
10.1038/s41576-021-00412-1 · ExternalCitation · doi-reference
Molecular mechanisms of transgenerational epigenetic inheritance
10.1038/s41576-021-00438-5 · ExternalCitation · doi-reference
Plant and animal small RNA communications between cells and organisms
10.1038/s41580-021-00425-y · ExternalCitation · doi-reference
C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance
10.1038/s41586-020-2699-5 · ExternalCitation · doi-reference
Predatory aggression evolved through adaptations to noradrenergic circuits
10.1038/s41586-025-10009-x · ExternalCitation · doi-reference
The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation
10.1038/s41586-026-10232-0 · ExternalCitation · doi-reference
Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny
10.1038/s41594-026-01816-5 · ExternalCitation · doi-reference
Geometric morphometrics of microscopic animals as exemplified by model nematodes
10.1038/s41596-020-0347-z · ExternalCitation · doi-reference
Functional divergence of conserved developmental plasticity genes between two distantly related nematodes
10.1038/s41598-025-14207-5 · ExternalCitation · doi-reference
Natural RNA interference directs a heritable response to the environment
10.1038/srep07387 · ExternalCitation · doi-reference
New genetic regulators question relevance of abundant yolk protein production in C. Elegans
10.1038/srep16381 · ExternalCitation · doi-reference
Developmental plasticity and the origin of species differences
10.1073/pnas.0501844102 · ExternalCitation · doi-reference
Double-stranded RNA made in C. elegans neurons can enter the germline and cause transgenerational gene silencing
10.1073/pnas.1423333112 · ExternalCitation · doi-reference
Extracellular RNA is transported from one generation to the next in Caenorhabditis elegans
10.1073/pnas.1608959113 · ExternalCitation · doi-reference
A Mediator subunit imparts robustness to a polyphenism decision
10.1073/pnas.2308816120 · ExternalCitation · doi-reference
Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum
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Intraguild predation between Pristionchus pacificus and Caenorhabditis elegans: a complex interaction with the potential for aggressive behaviour
10.1080/01677063.2020.1833004 · ExternalCitation · doi-reference
Immunological studies of insect metamorphosis: II. The role of a sex-limited blood protein in egg formation by the Cecropia silkworm
10.1085/jgp.37.4.539 · ExternalCitation · doi-reference
Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte
10.1091/mbc.10.12.4311 · ExternalCitation · doi-reference
Experimental and theoretical support for costs of plasticity and phenotype in a nematode cannibalistic trait
10.1093/evlett/qrac001 · ExternalCitation · doi-reference
Characterization of the Pristionchus pacificus “ epigenetic toolkit ” reveals the evolutionary loss of the histone methyltransferase complex PRC2
10.1093/genetics/iyae041 · ExternalCitation · doi-reference
ADR-2 regulates fertility and oocyte fate in Caenorhabditis elegans
10.1093/genetics/iyae114 · ExternalCitation · doi-reference
Production of YP170 vitellogenins promotes intestinal senescence in Caenorhabditis elegans
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