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References from Integrated transcriptomics approach identifies the upregulated SLC7A5, and associated pathways across different thyroid cancer cell types. Local targets link to admitted publications; unresolved targets remain external evidence.
Transcriptome of anaplastic thyroid cancer reveals two molecular subtypes with distinct tumor microenvironment and prognosis
10.1089/thy.2024.0266 · 2025 · External reference
STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1
10.1038/s41388-022-02273-2 · 2022 · External reference
Molecular pathology of thyroid tumors: essential points to comprehend regarding the latest WHO classification
10.3390/biomedicines12040712 · 2024 · External reference
Anaplastic thyroid cancer: improved understanding of what remains a deadly disease
10.1016/j.surge.2023.10.002 · 2024 · External reference
Circulating biomarkers of thyroid cancer: an appraisal
10.3390/jcm14051582 · 2025 · External reference
SCARF1: a multifaceted, yet largely understudied, scavenger receptor
10.1007/s00011-018-1154-7 · 2018 · External reference
SLC7A7 is a prognostic biomarker correlated with immune infiltrates in non-small cell lung cancer
10.1186/s12935-021-01781-7 · 2021 · External reference
Spindle function and Wnt pathway inhibition by PBX1 to suppress tumor progression via downregulating DCDC2 in colorectal cancer
10.1038/s41389-023-00448-4 · 2023 · External reference
SLC7A5 is required for cancer cell growth under arginine-limited conditions
10.1016/j.celrep.2024.115130 · 2025 · External reference
Integrated bioinformatics analysis and screening of hub genes in papillary thyroid carcinoma
10.1371/journal.pone.0251962 · 2021 · External reference
The revolution of targeted therapies in thyroid cancer treatment: present and future promising anti-cancer drugs
10.3390/ijms26083663 · 2025 · External reference
Prognostic and clinical significance of Solute Carrier Family 7 Member 1 in ovarian cancer
10.21037/tcr-20-2744 · 2021 · External reference
New developments in epigenetic and genetic biomarkers for differentiated thyroid cancer (DTC): moving toward accurate diagnosis and treatment by 2025
10.34172/bma.26 · 2025 · External reference
Structure, function and pharmacology of SLC7 family members and homologues
10.2533/chimia.2022.1011 · 2022 · External reference
The clinopathological and prognostic significance of SPOCK1 in gynecological cancers: a bioinformatics based analysis
10.3390/biology14020209 · 2025 · External reference
Identification and validation of hub genes involved in papillary thyroid carcinoma progression
10.1186/s12885-026-15841-6 · 2026 · External reference
Mechanistic insights of thyroid cancer progression
10.1210/endocr/bqad118 · 2023 · External reference
Clinical characteristics and outcomes of clinically detected versus imaging-detected incidental thyroid cancer
10.1016/j.eprac.2026.02.005 · 2026 · External reference
Thyroid cancer in adolescents and young adults: a population-based study in 185 countries worldwide
10.1016/s2213-8587(25)00289-x · 2026 · External reference
A gene set enrichment analysis for cancer hallmarks
10.1016/j.jpha.2024.101065 · 2025 · External reference
Prevalence and diagnostic reliability of BRAF, RAS mutations, and RET/PTC rearrangements in a Latin American public health service population with thyroid nodular disease
10.1371/journal.pone.0329407 · 2025 · External reference
Anaplastic thyroid carcinoma with unusual long-term survival: a case report
10.1186/s13256-021-03249-8 · 2022 · External reference
Targeting SLC1A5 and SLC3A2/SLC7A5 as a potential strategy to strengthen anti-tumor immunity in the tumor microenvironment
10.3389/fimmu.2021.624324 · 2021 · External reference
Decoding the mutational hierarchy of thyroid cancer and associated signaling pathways
10.1016/j.arcmed.2025.103366 · 2026 · External reference
Integrated transcriptome sequencing and weighted gene co-expression network analysis reveals key genes of papillary thyroid carcinomas
10.1016/j.heliyon.2024.e27928 · 2024 · External reference
RNA sequencing identifies crucial genes in papillary thyroid carcinoma (PTC) progression
10.1016/j.yexmp.2015.12.011 · 2016 · External reference
Diagnostic role of Galectin-3 immunohistochemistry in thyroid lesions
10.4103/jhnps.jhnps_37_22 · 2022 · External reference
The human SLC7A5 (LAT1): the intriguing histidine/large neutral amino acid transporter and its relevance to human health
10.3389/fchem.2018.00243 · 2018 · External reference
Clinical implications of mTOR expression in papillary thyroid cancer—A systematic review
10.3390/cancers15061665 · 2023 · External reference
Identification of potential biomarkers for thyroid cancer using bioinformatics strategy: a study based on GEO datasets
10.1155/2020/9710421 · 2020 · External reference
The amino acid transporter Slc7a5 regulates the mTOR pathway and is required for granule cell development
10.1093/hmg/ddaa186 · 2020 · External reference
Identification of differentially expressed genes and signaling pathways in papillary thyroid cancer: a study based on integrated microarray and bioinformatics analysis
10.21037/gs-20-673 · 2021 · External reference
The STRING database in 2025: protein networks with directionality of regulation
10.1093/nar/gkae1113 · 2025 · External reference
State of the art on thyroid cancer biology and oncology
10.3390/biomedicines14010168 · 2026 · External reference
The knockdown of ETV4 inhibits the papillary thyroid cancer development by promoting ferroptosis upon SLC7A11 downregulation
10.1089/dna.2021.0216 · 2021 · External reference
N7-methyladenosine-induced SLC7A7 serves as a prognostic biomarker in pan-cancer and promotes CRC progression in colorectal cancer
10.1038/s41598-024-80885-2 · 2024 · External reference
New insights into the mechanisms of the extracellular matrix and its therapeutic potential in anaplastic thyroid carcinoma
10.1038/s41598-024-72020-y · 2024 · External reference
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling
10.18632/aging.202231 · 2020 · External reference
SLC7 transporters at the crossroads of amino acid metabolism and diabetes pathophysiology: insights and therapeutic perspectives
10.3389/fnut.2025.1467057 · External reference
Abnormal activation of the Ras/MAPK signaling pathway in oncogenesis and progression
10.53388/2025825002 · External reference
Identification of key genes of papillary thyroid carcinoma by integrated bioinformatics analysis
10.1042/bsr20201555 · 2020 · External reference
Network-based meta-analysis in the identification of biomarkers for papillary thyroid cancer
10.1016/j.gene.2018.03.096 · 2018 · External reference
