Research graph
References from Cross-phenotype integration of eQTL-based Mendelian randomization and transcriptomics prioritizes BMP2K in IgA vasculitis with nephritis. Local targets link to admitted publications; unresolved targets remain external evidence.
Iga vasculitis
10.1007/s00281-021-00874-9 · 2021 · External reference
Histologic and clinical factors associated with kidney outcomes in iga vasculitis nephritis
10.2215/cjn.0000000000000398 · 2024 · External reference
Updates on the diagnosis, prognosis, and management of iga vasculitis in adults: a narrative review
10.1016/j.jaad.2026.02.007 · 2026 · External reference
Kidney injury and colocalization of complement c3, iga, and igg in glomerular immune-complex deposits of patients with iga nephropathy or iga vasculitis with nephritis
10.1016/j.kint.2025.07.038 · 2025 · External reference
Iga glycosylation and immune complex formation in igan
10.1007/s00281-021-00883-8 · 2021 · External reference
The association between fractalkine/cx3cr1 axis with iga vasculitis and nephritis
10.1038/s41390-025-03957-7 · 2026 · External reference
Galactosylation of iga1 is associated with common variation in c1galt1
10.1681/asn.2016091043 · 2017 · External reference
Germline c1galt1c1 mutation causes a multisystem chaperonopathy
10.1073/pnas.2211087120 · 2023 · External reference
Association between tnfsf13 snps and progression to end-stage renal disease in iga nephropathy patients
10.1007/s11255-026-05222-0 · 2026 · External reference
Hla-dqb1 and hla-drb1 expression is associated with disease severity in igan
10.21037/apm-21-2065 · 2021 · External reference
Diagnostic and management strategies of iga vasculitis nephritis/henoch-schönlein purpura nephritis in pediatric patients: current perspectives
10.2147/phmt.s379862 · 2023 · External reference
Mendelian randomization for nephrologists
10.1016/j.kint.2023.09.016 · 2023 · External reference
Causal relationships between circulating inflammatory factors and iga vasculitis: a bidirectional mendelian randomization study
10.3389/fimmu.2023.1248325 · 2023 · External reference
Differential expression of long non-coding rna and mrna in children with henoch-schönlein purpura nephritis
10.3892/etm.2018.7038 · 2019 · External reference
Multi-omics mendelian randomization integrating gwas, eqtl and pqtl data revealed gstm4 as a potential drug target for migraine
10.1186/s10194-024-01828-w · 2024 · External reference
Small non-coding rnaome of ageing chondrocytes
10.3390/ijms21165675 · 2020 · External reference
Combined periodontitis gwas identifies linc01541 as a regulator of innate immunity in the oral mucosa
10.1093/hmg/ddag039 · 2026 · External reference
Scqtlbase: an integrated human single-cell eqtl database
10.1093/nar/gkad781 · 2024 · External reference
Eular/printo/pres criteria for henoch-schönlein purpura, childhood polyarteritis nodosa, childhood wegener granulomatosis and childhood takayasu arteritis: ankara 2008. part ii: final classification criteria
10.1136/ard.2009.116657 · 2010 · External reference
Dsigdb: drug signatures database for gene set analysis
10.1093/bioinformatics/btv313 · 2015 · External reference
Crispr-cas9 editing of human histone deubiquitinase gene usp16 in human monocytic leukemia cell line thp-1
10.3389/fcell.2021.679544 · 2021 · External reference
Ruboxistaurin maintains the bone mass of subchondral bone for blunting osteoarthritis progression by inhibition of osteoclastogenesis and bone resorption activity
10.1016/j.biopha.2020.110650 · 2020 · External reference
Cytokine-cytokine receptor interaction and endocytosis are common pathways for symptom burden and sickness behavior symptoms in oncology patients undergoing chemotherapy
10.1002/cam4.71328 · 2025 · External reference
Elevated urinary monocyte chemoattractant protein-1 levels in children with henoch-schonlein purpura nephritis
10.1016/j.pedneo.2017.08.008 · 2018 · External reference
Effects of adma upon gene expression: an insight into the pathophysiological significance of raised plasma adma
10.1371/journal.pmed.0020264 · 2005 · External reference
Identifying candidate genes for type 2 diabetes mellitus and obesity through gene expression profiling in multiple tissues or cells
10.1155/2013/970435 · 2013 · External reference
Gene expression profiling in ethnic malays with type 2 diabetes mellitus, with and without diabetic nephropathy
10.5301/jn.2011.6382 · 2011 · External reference
Early-onset pulmonary and cutaneous vasculitis driven by constitutively active src-family kinase hck
10.1016/j.jaci.2021.07.046 · 2022 · External reference
Occupational exposure to carbon black nanoparticles increases inflammatory vascular disease risk: an implication of an ex vivo biosensor assay
10.1186/s12989-020-00378-8 · 2020 · External reference
Saharan dust induces nlrp3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model
10.1186/s12989-023-00550-w · 2023 · External reference
Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs
10.1186/s12974-019-1690-2 · 2020 · External reference
Role of protein kinase c in metabolic regulation of coronary endothelial small conductance calcium-activated potassium channels
10.1161/jaha.123.031028 · 2024 · External reference
Protein kinase c beta inhibition: the promise for treatment of diabetic nephropathy
10.1097/mnh.0b013e3281ead025 · 2007 · External reference
The next generation of diabetic nephropathy therapies: an update
10.1053/j.ackd.2005.01.011 · 2005 · External reference
Pkcβ expression contributes to m1 macrophage-induced impairment in the osteogenic differentiation of periodontal ligament stem cells
10.1007/s11626-025-01032-3 · 2025 · External reference
Cytokine-cytokine receptor interaction and endocytosis are common pathways for symptom burden and sickness behavior symptoms in oncology patients undergoing chemotherapy
10.1002/cam4.71328 · ExternalCitation · doi-reference
Iga vasculitis
10.1007/s00281-021-00874-9 · ExternalCitation · doi-reference
Iga glycosylation and immune complex formation in igan
10.1007/s00281-021-00883-8 · ExternalCitation · doi-reference
Association between tnfsf13 snps and progression to end-stage renal disease in iga nephropathy patients
10.1007/s11255-026-05222-0 · ExternalCitation · doi-reference
Pkcβ expression contributes to m1 macrophage-induced impairment in the osteogenic differentiation of periodontal ligament stem cells
10.1007/s11626-025-01032-3 · ExternalCitation · doi-reference
Ruboxistaurin maintains the bone mass of subchondral bone for blunting osteoarthritis progression by inhibition of osteoclastogenesis and bone resorption activity
10.1016/j.biopha.2020.110650 · ExternalCitation · doi-reference
Updates on the diagnosis, prognosis, and management of iga vasculitis in adults: a narrative review
10.1016/j.jaad.2026.02.007 · ExternalCitation · doi-reference
Early-onset pulmonary and cutaneous vasculitis driven by constitutively active src-family kinase hck
10.1016/j.jaci.2021.07.046 · ExternalCitation · doi-reference
Mendelian randomization for nephrologists
10.1016/j.kint.2023.09.016 · ExternalCitation · doi-reference
Kidney injury and colocalization of complement c3, iga, and igg in glomerular immune-complex deposits of patients with iga nephropathy or iga vasculitis with nephritis
10.1016/j.kint.2025.07.038 · ExternalCitation · doi-reference
Elevated urinary monocyte chemoattractant protein-1 levels in children with henoch-schonlein purpura nephritis
10.1016/j.pedneo.2017.08.008 · ExternalCitation · doi-reference
The association between fractalkine/cx3cr1 axis with iga vasculitis and nephritis
10.1038/s41390-025-03957-7 · ExternalCitation · doi-reference
The next generation of diabetic nephropathy therapies: an update
10.1053/j.ackd.2005.01.011 · ExternalCitation · doi-reference
Germline c1galt1c1 mutation causes a multisystem chaperonopathy
10.1073/pnas.2211087120 · ExternalCitation · doi-reference
Dsigdb: drug signatures database for gene set analysis
10.1093/bioinformatics/btv313 · ExternalCitation · doi-reference
Combined periodontitis gwas identifies linc01541 as a regulator of innate immunity in the oral mucosa
10.1093/hmg/ddag039 · ExternalCitation · doi-reference
Scqtlbase: an integrated human single-cell eqtl database
10.1093/nar/gkad781 · ExternalCitation · doi-reference
Protein kinase c beta inhibition: the promise for treatment of diabetic nephropathy
10.1097/mnh.0b013e3281ead025 · ExternalCitation · doi-reference
Eular/printo/pres criteria for henoch-schönlein purpura, childhood polyarteritis nodosa, childhood wegener granulomatosis and childhood takayasu arteritis: ankara 2008. part ii: final classification criteria
10.1136/ard.2009.116657 · ExternalCitation · doi-reference
Identifying candidate genes for type 2 diabetes mellitus and obesity through gene expression profiling in multiple tissues or cells
10.1155/2013/970435 · ExternalCitation · doi-reference
Role of protein kinase c in metabolic regulation of coronary endothelial small conductance calcium-activated potassium channels
10.1161/jaha.123.031028 · ExternalCitation · doi-reference
Multi-omics mendelian randomization integrating gwas, eqtl and pqtl data revealed gstm4 as a potential drug target for migraine
10.1186/s10194-024-01828-w · ExternalCitation · doi-reference
Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs
10.1186/s12974-019-1690-2 · ExternalCitation · doi-reference
Occupational exposure to carbon black nanoparticles increases inflammatory vascular disease risk: an implication of an ex vivo biosensor assay
10.1186/s12989-020-00378-8 · ExternalCitation · doi-reference
Saharan dust induces nlrp3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model
10.1186/s12989-023-00550-w · ExternalCitation · doi-reference
Effects of adma upon gene expression: an insight into the pathophysiological significance of raised plasma adma
10.1371/journal.pmed.0020264 · ExternalCitation · doi-reference
Galactosylation of iga1 is associated with common variation in c1galt1
10.1681/asn.2016091043 · ExternalCitation · doi-reference
Hla-dqb1 and hla-drb1 expression is associated with disease severity in igan
10.21037/apm-21-2065 · ExternalCitation · doi-reference
Diagnostic and management strategies of iga vasculitis nephritis/henoch-schönlein purpura nephritis in pediatric patients: current perspectives
10.2147/phmt.s379862 · ExternalCitation · doi-reference
Histologic and clinical factors associated with kidney outcomes in iga vasculitis nephritis
10.2215/cjn.0000000000000398 · ExternalCitation · doi-reference
Crispr-cas9 editing of human histone deubiquitinase gene usp16 in human monocytic leukemia cell line thp-1
10.3389/fcell.2021.679544 · ExternalCitation · doi-reference
Causal relationships between circulating inflammatory factors and iga vasculitis: a bidirectional mendelian randomization study
10.3389/fimmu.2023.1248325 · ExternalCitation · doi-reference
Small non-coding rnaome of ageing chondrocytes
10.3390/ijms21165675 · ExternalCitation · doi-reference
Differential expression of long non-coding rna and mrna in children with henoch-schönlein purpura nephritis
10.3892/etm.2018.7038 · ExternalCitation · doi-reference
Gene expression profiling in ethnic malays with type 2 diabetes mellitus, with and without diabetic nephropathy
10.5301/jn.2011.6382 · ExternalCitation · doi-reference
