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References from Neutrophil extracellular traps in colorectal cancer: a paradoxical nexus of tumor defense and disease progression. Local targets link to admitted publications; unresolved targets remain external evidence.
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
10.3322/caac.21834 · 2024 · External reference
The global, regional, and national burden of cancer, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
10.1016/s0140-6736(25)01635-6 · 2025 · External reference
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
10.1016/j.ccell.2023.02.016 · 2023 · External reference
The tumor microenvironment’s role in the response to immune checkpoint blockade
10.1038/s43018-025-00986-3 · 2025 · External reference
The multifaceted functions of neutrophils
10.1146/annurev-pathol-020712-164023 · 2014 · External reference
Therapeutic potential of tumor-associated neutrophils: dual role and phenotypic plasticity
10.1038/s41392-025-02242-7 · 2025 · External reference
The prognostic landscape of genes and infiltrating immune cells across human cancers
10.1038/nm.3909 · 2015 · External reference
Rapid killing of human neutrophils by the potent activator phorbol 12-myristate 13-acetate (PMA) accompanied by changes different from typical apoptosis or necrosis
10.1002/jlb.59.2.229 · 1996 · External reference
Neutrophil extracellular traps kill bacteria
10.1126/science.1092385 · 2004 · External reference
NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps
10.1016/j.ccell.2023.02.001 · 2023 · External reference
Neutrophil extracellular traps in cancer
10.1002/mco2.647 · 2024 · External reference
Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases
10.1152/physrev.00062.2021 · 2023 · External reference
Neutrophil extracellular traps in immunity and disease
10.1038/nri.2017.105 · 2018 · External reference
Diverse stimuli engage different neutrophil extracellular trap pathways
10.7554/elife.24437 · 2017 · External reference
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
10.1038/nchembio.1735 · 2015 · External reference
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
10.1083/jcb.200806072 · 2009 · External reference
Molecular mechanisms and therapeutic target of NETosis in diseases
10.1002/mco2.162 · 2022 · External reference
SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx
10.1073/pnas.1414055112 · 2015 · External reference
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
10.1038/nm.4027 · 2016 · External reference
A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to staphylococcus aureus
10.4049/jimmunol.1000675 · 2010 · External reference
PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures
10.3389/fimmu.2012.00307 · 2012 · External reference
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps
10.1126/sciimmunol.aar6689 · 2018 · External reference
IL-8 mediates a positive loop connecting increased neutrophil extracellular traps (NETs) and colorectal cancer liver metastasis
10.7150/jca.44215 · 2020 · External reference
SKAP1 expression in cancer cells enhances colon tumor growth and impairs cytotoxic immunity by promoting neutrophil extracellular trap formation via the NFATc1/CXCL8 axis
10.1002/advs.202403430 · 2024 · External reference
FGF19‐induced inflammatory CAF promoted neutrophil extracellular trap formation in the liver metastasis of colorectal cancer
10.1002/advs.202302613 · 2023 · External reference
Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression
10.1186/s13046-023-02817-8 · 2023 · External reference
Exosomal KRAS mutation promotes the formation of tumor-associated neutrophil extracellular traps and causes deterioration of colorectal cancer by inducing IL-8 expression
10.1186/s12964-020-0517-1 · 2020 · External reference
Targeting NADPH oxidase and integrin α5β1 to inhibit neutrophil extracellular traps-mediated metastasis in colorectal cancer
10.3390/ijms242116001 · 2023 · External reference
Increased PADI4 expression in blood and tissues of patients with Malignant tumors
10.1186/1471-2407-9-40 · 2009 · External reference
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA
10.1186/s13073-022-01125-8 · 2022 · External reference
Association of neutrophil extracellular traps with the production of circulating DNA in patients with colorectal cancer
10.1016/j.isci.2022.103826 · 2022 · External reference
Neutrophil extracellular trap production in patients with colorectal cancer in vitro
10.1155/2017/4915062 · 2017 · External reference
Biomarkers of peripheral blood neutrophil extracellular traps in the diagnosis and progression of Malignant tumors
10.1002/cam4.6935 · 2024 · External reference
A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics
10.1007/s12016-020-08804-7 · 2021 · External reference
Neutrophil extracellular traps promote the development and progression of liver metastases after surgical stress
10.1016/j.hpb.2017.02.210 · 2017 · External reference
Neutrophil extracellular traps promote metastases of colorectal cancers through activation of ERK signaling by releasing neutrophil elastase
10.3390/ijms24021118 · 2023 · External reference
Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer
10.1371/journal.pone.0191231 · 2018 · External reference
Neutrophil extracellular traps as biomarkers for predicting prognosis and chemotherapy response in colorectal cancer
10.1038/s41598-025-29093-0 · 2026 · External reference
Neutrophil extracellular traps (NETs)-score: A novel prognostic marker for colorectal cancer patients
10.1007/s12672-025-03708-4 · 2025 · External reference
Inflammation and colorectal cancer: colitis-associated neoplasia
10.1007/s00281-012-0352-6 · 2013 · External reference
Neutrophil extracellular traps sustain inflammatory signals in ulcerative colitis
10.1093/ecco-jcc/jjy215 · 2019 · External reference
Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs
10.1016/j.phymed.2022.154454 · 2022 · External reference
Neutrophil extracellular traps induce intestinal damage and thrombotic tendency in inflammatory bowel disease
10.1093/ecco-jcc/jjz132 · 2020 · External reference
Glycyrrhizic acid reduces neutrophil extracellular trap formation to ameliorate colitis-associated colorectal cancer by inhibiting peptidylarginine deiminase 4
10.1016/j.jep.2025.119337 · 2025 · External reference
Parasutterella excrementihominis exacerbates experimental colitis and colitis-associated colorectal cancer via pathogenic NETosis activation
10.1136/gutjnl-2025-335887 · 2026 · External reference
Neutrophil-derived serine proteases induce FOXA2-mediated autophagy dysfunction and exacerbate colitis-associated carcinogenesis via protease activated receptor 2
10.1080/15548627.2025.2489335 · 2025 · External reference
Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice
10.1371/journal.pone.0051848 · 2012 · External reference
CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity
10.1016/j.immuni.2020.03.001 · 2020 · External reference
Region-specific CD16+ Neutrophils promote colorectal cancer progression by inhibiting natural killer cells
10.1002/advs.202403414 · 2024 · External reference
Granulocyte-like myeloid-derived suppressor cells: The culprits of neutrophil extracellular traps formation in the pre-metastatic niche
10.1016/j.intimp.2024.113500 · 2024 · External reference
Neutrophil extracellular traps drive mitochondrial homeostasis in tumors to augment growth
10.1158/0008-5472.can-19-0800 · 2019 · External reference
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
10.1172/jci67484 · 2013 · External reference
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25
10.1038/s41586-020-2394-6 · 2020 · External reference
Neutrophil extracellular traps promote T cell exhaustion in the tumor microenvironment
10.3389/fimmu.2021.785222 · 2021 · External reference
Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation
10.1016/j.canlet.2025.217642 · 2025 · External reference
Oral streptococcus salivarius couples neutrophil IRGM1 signaling to NET formation and colorectal cancer metastasis
10.1002/advs.202516546 · 2026 · External reference
Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3
10.1186/s12967-023-03977-z · 2023 · External reference
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice
10.1126/science.aao4227 · 2018 · External reference
Neutrophil extracellular traps regulate LDHA expression to promote colorectal cancer liver metastasis
10.1186/s12967-025-07174-y · 2025 · External reference
Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation
10.1016/j.ccell.2023.03.008 · 2023 · External reference
Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer
10.1172/jci175031 · 2024 · External reference
Neutrophil extracellular traps as a unique target in the treatment of chemotherapy-induced peripheral neuropathy
10.1016/j.ebiom.2023.104499 · 2023 · External reference
DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps
10.1016/j.ccell.2025.07.014 · 2025 · External reference
Inhibition of neutrophil extracellular traps via the FGF19/ERK/IL-8 axis enhances immune therapy in MSS colorectal cancer
10.1016/j.clim.2026.110664 · 2026 · External reference
Surgery-induced neutrophil extracellular traps promote tumor metastasis by reprogramming cancer cell lipid metabolism
10.1158/0008-5472.can-24-3393 · 2025 · External reference
Cryoablation-induced neutrophil Ca2+ elevation and NET formation exacerbate immune escape in colorectal cancer liver metastasis
10.1186/s13046-024-03244-z · 2024 · External reference
Neutrophil extracellular traps: potential thrombotic markers and therapeutic targets in colorectal cancer
10.1093/jleuko/qiae235 · 2025 · External reference
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice
10.1182/blood-2016-04-710632 · 2016 · External reference
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
10.1016/j.cell.2021.04.016 · 2021 · External reference
Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24
10.1136/jitc-2024-010813 · 2025 · External reference
Tumour-associated neutrophils in patients with cancer
10.1038/s41571-019-0222-4 · 2019 · External reference
Neutrophil extracellular traps (NET) induced by different stimuli: A comparative proteomic analysis
10.1371/journal.pone.0218946 · 2019 · External reference
Total cell-free DNA measurement in metastatic colorectal cancer with a fast and easy direct fluorescent assay
10.3892/mco.2022.2497 · 2022 · External reference
Measurement of NET formation in vitro and in vivo by flow cytometry
10.1002/cyto.a.23169 · 2017 · External reference
Establishment of a multi-parameter flow cytometry method to identify and characterize neutrophil extracellular traps
10.1016/j.cellimm.2025.105014 · 2025 · External reference
A novel image-based quantitative method for the characterization of NETosis
10.1016/j.jim.2015.04.027 · 2015 · External reference
Significance of tumor infiltrating granulocytes and neutrophil extracellular traps in colorectal cancer
10.1038/s41416-026-03409-x · 2026 · External reference
Integrative single-cell and spatial multi-omics analyses identify NETs-driven colon cancer subtypes with distinct metabolic features and prognostic implications
10.1186/s12967-026-08227-6 · 2026 · External reference
Multi-omics analysis reveals that neutrophil extracellular traps related gene TIMP1 promotes CRC progression and influences ferroptosis
10.1186/s12935-025-03643-y · 2025 · External reference
Label-free virtual staining of neutrophil extracellular traps (NETs) in microfluidics
10.1039/d3lc00398a · 2023 · External reference
Comparison of NET quantification methods based on immunofluorescence microscopy: Hand-counting, semi-automated and automated evaluations
10.1016/j.heliyon.2023.e16982 · 2023 · External reference
GSK484, an inhibitor of peptidyl arginine deiminase 4, increases the radiosensitivity of colorectal cancer and inhibits neutrophil extracellular traps
10.1002/jgm.3530 · 2023 · External reference
Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer
10.18632/oncotarget.5937 · 2015 · External reference
A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression
10.1158/0008-5472.can-21-4045 · 2022 · External reference
Repurposing indacaterol as a novel NETs inhibitor for the treatment of colorectal tumor metastasis
10.1016/j.bcp.2026.118106 · 2026 · External reference
The CXCL8-CXCR1/2 pathways in cancer
10.1016/j.cytogfr.2016.08.002 · 2016 · External reference
The CXCR2 antagonist, SCH-527123, shows antitumor activity and sensitizes cells to oxaliplatin in preclinical colon cancer models
10.1158/1535-7163.mct-11-0915 · 2012 · External reference
Advances in immunotherapy for MMR proficient colorectal cancer
10.1016/j.ctrv.2022.102480 · 2022 · External reference
Wrecking neutrophil extracellular traps and antagonizing cancer-associated neurotransmitters by interpenetrating network hydrogels prevent postsurgical cancer relapse and metastases
10.1016/j.bioactmat.2024.05.022 · 2024 · External reference
Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation
10.1016/j.jare.2024.10.036 · 2025 · External reference
Mechanism of Xianlian Jiedu Formula in inhibiting colorectal cancer liver metastasis by regulating neutrophil extracellular traps
2025 · External reference
Mechanism of Huangqi–Ezhu components in inhibiting NETs-mediated colorectal cancer liver metastasis through the VE-cadherin/β-catenin signaling pathway
2025 · External reference
Inulin-based oral chemotherapy modulates gut microbiota and immune microenvironment through inhibition of neutrophil extracellular trap formation for improving cancer therapy
10.1002/advs.202514318 · 2026 · External reference
Radioactive hydrogel with NETs degradation capacity for the boosted tumor radio-immunotherapy
10.1016/j.mtbio.2025.102689 · 2026 · External reference
TME-responsive nanoparticles co-targeting VCP, NETs, and dual immune checkpoints for immune revitalization in EGFR/PD-L1/CTLA-4–driven colorectal cancer
10.1016/j.biopha.2025.118565 · 2025 · External reference
AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response
10.1002/1878-0261.12787 · 2020 · External reference
Neutrophil extracellular traps in host defense
10.1101/cshperspect.a037028 · 2020 · External reference
Neutrophil extracellular traps in colorectal cancer progression and metastasis
10.3390/ijms22147260 · 2021 · External reference
Tumor-associated neutrophils and neutrophil-targeted cancer therapies
10.1016/j.bbcan.2022.188762 · 2022 · External reference
Targeting and exploitation of tumor-associated neutrophils to enhance immunotherapy and drug delivery for cancer treatment
10.20892/j.issn.2095-3941.2019.0372 · 2020 · External reference
Composition and function of neutrophil extracellular traps
10.3390/biom14040416 · 2024 · External reference
Neutrophil diversity and plasticity in tumour progression and therapy
10.1038/s41568-020-0281-y · 2020 · External reference
Machine learning to quantitate neutrophil NETosis
10.1038/s41598-019-53202-5 · 2019 · External reference
Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome
10.1002/path.6378 · 2025 · External reference
AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response
10.1002/1878-0261.12787 · ExternalCitation · doi-reference
FGF19‐induced inflammatory CAF promoted neutrophil extracellular trap formation in the liver metastasis of colorectal cancer
10.1002/advs.202302613 · ExternalCitation · doi-reference
Region-specific CD16+ Neutrophils promote colorectal cancer progression by inhibiting natural killer cells
10.1002/advs.202403414 · ExternalCitation · doi-reference
SKAP1 expression in cancer cells enhances colon tumor growth and impairs cytotoxic immunity by promoting neutrophil extracellular trap formation via the NFATc1/CXCL8 axis
10.1002/advs.202403430 · ExternalCitation · doi-reference
Inulin-based oral chemotherapy modulates gut microbiota and immune microenvironment through inhibition of neutrophil extracellular trap formation for improving cancer therapy
10.1002/advs.202514318 · ExternalCitation · doi-reference
Oral streptococcus salivarius couples neutrophil IRGM1 signaling to NET formation and colorectal cancer metastasis
10.1002/advs.202516546 · ExternalCitation · doi-reference
Biomarkers of peripheral blood neutrophil extracellular traps in the diagnosis and progression of Malignant tumors
10.1002/cam4.6935 · ExternalCitation · doi-reference
Measurement of NET formation in vitro and in vivo by flow cytometry
10.1002/cyto.a.23169 · ExternalCitation · doi-reference
GSK484, an inhibitor of peptidyl arginine deiminase 4, increases the radiosensitivity of colorectal cancer and inhibits neutrophil extracellular traps
10.1002/jgm.3530 · ExternalCitation · doi-reference
Rapid killing of human neutrophils by the potent activator phorbol 12-myristate 13-acetate (PMA) accompanied by changes different from typical apoptosis or necrosis
10.1002/jlb.59.2.229 · ExternalCitation · doi-reference
Molecular mechanisms and therapeutic target of NETosis in diseases
10.1002/mco2.162 · ExternalCitation · doi-reference
Neutrophil extracellular traps in cancer
10.1002/mco2.647 · ExternalCitation · doi-reference
Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome
10.1002/path.6378 · ExternalCitation · doi-reference
Inflammation and colorectal cancer: colitis-associated neoplasia
10.1007/s00281-012-0352-6 · ExternalCitation · doi-reference
A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics
10.1007/s12016-020-08804-7 · ExternalCitation · doi-reference
Neutrophil extracellular traps (NETs)-score: A novel prognostic marker for colorectal cancer patients
10.1007/s12672-025-03708-4 · ExternalCitation · doi-reference
Tumor-associated neutrophils and neutrophil-targeted cancer therapies
10.1016/j.bbcan.2022.188762 · ExternalCitation · doi-reference
Repurposing indacaterol as a novel NETs inhibitor for the treatment of colorectal tumor metastasis
10.1016/j.bcp.2026.118106 · ExternalCitation · doi-reference
Wrecking neutrophil extracellular traps and antagonizing cancer-associated neurotransmitters by interpenetrating network hydrogels prevent postsurgical cancer relapse and metastases
10.1016/j.bioactmat.2024.05.022 · ExternalCitation · doi-reference
TME-responsive nanoparticles co-targeting VCP, NETs, and dual immune checkpoints for immune revitalization in EGFR/PD-L1/CTLA-4–driven colorectal cancer
10.1016/j.biopha.2025.118565 · ExternalCitation · doi-reference
Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation
10.1016/j.canlet.2025.217642 · ExternalCitation · doi-reference
NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps
10.1016/j.ccell.2023.02.001 · ExternalCitation · doi-reference
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
10.1016/j.ccell.2023.02.016 · ExternalCitation · doi-reference
Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation
10.1016/j.ccell.2023.03.008 · ExternalCitation · doi-reference
DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps
10.1016/j.ccell.2025.07.014 · ExternalCitation · doi-reference
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
10.1016/j.cell.2021.04.016 · ExternalCitation · doi-reference
Establishment of a multi-parameter flow cytometry method to identify and characterize neutrophil extracellular traps
10.1016/j.cellimm.2025.105014 · ExternalCitation · doi-reference
Inhibition of neutrophil extracellular traps via the FGF19/ERK/IL-8 axis enhances immune therapy in MSS colorectal cancer
10.1016/j.clim.2026.110664 · ExternalCitation · doi-reference
Advances in immunotherapy for MMR proficient colorectal cancer
10.1016/j.ctrv.2022.102480 · ExternalCitation · doi-reference
The CXCL8-CXCR1/2 pathways in cancer
10.1016/j.cytogfr.2016.08.002 · ExternalCitation · doi-reference
Neutrophil extracellular traps as a unique target in the treatment of chemotherapy-induced peripheral neuropathy
10.1016/j.ebiom.2023.104499 · ExternalCitation · doi-reference
Comparison of NET quantification methods based on immunofluorescence microscopy: Hand-counting, semi-automated and automated evaluations
10.1016/j.heliyon.2023.e16982 · ExternalCitation · doi-reference
Neutrophil extracellular traps promote the development and progression of liver metastases after surgical stress
10.1016/j.hpb.2017.02.210 · ExternalCitation · doi-reference
CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity
10.1016/j.immuni.2020.03.001 · ExternalCitation · doi-reference
Granulocyte-like myeloid-derived suppressor cells: The culprits of neutrophil extracellular traps formation in the pre-metastatic niche
10.1016/j.intimp.2024.113500 · ExternalCitation · doi-reference
Association of neutrophil extracellular traps with the production of circulating DNA in patients with colorectal cancer
10.1016/j.isci.2022.103826 · ExternalCitation · doi-reference
Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation
10.1016/j.jare.2024.10.036 · ExternalCitation · doi-reference
Glycyrrhizic acid reduces neutrophil extracellular trap formation to ameliorate colitis-associated colorectal cancer by inhibiting peptidylarginine deiminase 4
10.1016/j.jep.2025.119337 · ExternalCitation · doi-reference
A novel image-based quantitative method for the characterization of NETosis
10.1016/j.jim.2015.04.027 · ExternalCitation · doi-reference
Radioactive hydrogel with NETs degradation capacity for the boosted tumor radio-immunotherapy
10.1016/j.mtbio.2025.102689 · ExternalCitation · doi-reference
Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs
10.1016/j.phymed.2022.154454 · ExternalCitation · doi-reference
The global, regional, and national burden of cancer, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
10.1016/s0140-6736(25)01635-6 · ExternalCitation · doi-reference
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
10.1038/nchembio.1735 · ExternalCitation · doi-reference
The prognostic landscape of genes and infiltrating immune cells across human cancers
10.1038/nm.3909 · ExternalCitation · doi-reference
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
10.1038/nm.4027 · ExternalCitation · doi-reference
Neutrophil extracellular traps in immunity and disease
10.1038/nri.2017.105 · ExternalCitation · doi-reference
Therapeutic potential of tumor-associated neutrophils: dual role and phenotypic plasticity
10.1038/s41392-025-02242-7 · ExternalCitation · doi-reference
Significance of tumor infiltrating granulocytes and neutrophil extracellular traps in colorectal cancer
10.1038/s41416-026-03409-x · ExternalCitation · doi-reference
Neutrophil diversity and plasticity in tumour progression and therapy
10.1038/s41568-020-0281-y · ExternalCitation · doi-reference
Tumour-associated neutrophils in patients with cancer
10.1038/s41571-019-0222-4 · ExternalCitation · doi-reference
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25
10.1038/s41586-020-2394-6 · ExternalCitation · doi-reference
Machine learning to quantitate neutrophil NETosis
10.1038/s41598-019-53202-5 · ExternalCitation · doi-reference
Neutrophil extracellular traps as biomarkers for predicting prognosis and chemotherapy response in colorectal cancer
10.1038/s41598-025-29093-0 · ExternalCitation · doi-reference
The tumor microenvironment’s role in the response to immune checkpoint blockade
10.1038/s43018-025-00986-3 · ExternalCitation · doi-reference
Label-free virtual staining of neutrophil extracellular traps (NETs) in microfluidics
10.1039/d3lc00398a · ExternalCitation · doi-reference
SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx
10.1073/pnas.1414055112 · ExternalCitation · doi-reference
Neutrophil-derived serine proteases induce FOXA2-mediated autophagy dysfunction and exacerbate colitis-associated carcinogenesis via protease activated receptor 2
10.1080/15548627.2025.2489335 · ExternalCitation · doi-reference
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
10.1083/jcb.200806072 · ExternalCitation · doi-reference
Neutrophil extracellular traps sustain inflammatory signals in ulcerative colitis
10.1093/ecco-jcc/jjy215 · ExternalCitation · doi-reference
Neutrophil extracellular traps induce intestinal damage and thrombotic tendency in inflammatory bowel disease
10.1093/ecco-jcc/jjz132 · ExternalCitation · doi-reference
Neutrophil extracellular traps: potential thrombotic markers and therapeutic targets in colorectal cancer
10.1093/jleuko/qiae235 · ExternalCitation · doi-reference
Neutrophil extracellular traps in host defense
10.1101/cshperspect.a037028 · ExternalCitation · doi-reference
Neutrophil extracellular traps kill bacteria
10.1126/science.1092385 · ExternalCitation · doi-reference
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice
10.1126/science.aao4227 · ExternalCitation · doi-reference
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps
10.1126/sciimmunol.aar6689 · ExternalCitation · doi-reference
Parasutterella excrementihominis exacerbates experimental colitis and colitis-associated colorectal cancer via pathogenic NETosis activation
10.1136/gutjnl-2025-335887 · ExternalCitation · doi-reference
Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24
10.1136/jitc-2024-010813 · ExternalCitation · doi-reference
The multifaceted functions of neutrophils
10.1146/annurev-pathol-020712-164023 · ExternalCitation · doi-reference
Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases
10.1152/physrev.00062.2021 · ExternalCitation · doi-reference
Neutrophil extracellular trap production in patients with colorectal cancer in vitro
10.1155/2017/4915062 · ExternalCitation · doi-reference
Neutrophil extracellular traps drive mitochondrial homeostasis in tumors to augment growth
10.1158/0008-5472.can-19-0800 · ExternalCitation · doi-reference
A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression
10.1158/0008-5472.can-21-4045 · ExternalCitation · doi-reference
Surgery-induced neutrophil extracellular traps promote tumor metastasis by reprogramming cancer cell lipid metabolism
10.1158/0008-5472.can-24-3393 · ExternalCitation · doi-reference
The CXCR2 antagonist, SCH-527123, shows antitumor activity and sensitizes cells to oxaliplatin in preclinical colon cancer models
10.1158/1535-7163.mct-11-0915 · ExternalCitation · doi-reference
Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer
10.1172/jci175031 · ExternalCitation · doi-reference
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
10.1172/jci67484 · ExternalCitation · doi-reference
Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice
10.1182/blood-2016-04-710632 · ExternalCitation · doi-reference
Increased PADI4 expression in blood and tissues of patients with Malignant tumors
10.1186/1471-2407-9-40 · ExternalCitation · doi-reference
Multi-omics analysis reveals that neutrophil extracellular traps related gene TIMP1 promotes CRC progression and influences ferroptosis
10.1186/s12935-025-03643-y · ExternalCitation · doi-reference
Exosomal KRAS mutation promotes the formation of tumor-associated neutrophil extracellular traps and causes deterioration of colorectal cancer by inducing IL-8 expression
10.1186/s12964-020-0517-1 · ExternalCitation · doi-reference
Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3
10.1186/s12967-023-03977-z · ExternalCitation · doi-reference
Neutrophil extracellular traps regulate LDHA expression to promote colorectal cancer liver metastasis
10.1186/s12967-025-07174-y · ExternalCitation · doi-reference
Integrative single-cell and spatial multi-omics analyses identify NETs-driven colon cancer subtypes with distinct metabolic features and prognostic implications
10.1186/s12967-026-08227-6 · ExternalCitation · doi-reference
Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression
10.1186/s13046-023-02817-8 · ExternalCitation · doi-reference
Cryoablation-induced neutrophil Ca2+ elevation and NET formation exacerbate immune escape in colorectal cancer liver metastasis
10.1186/s13046-024-03244-z · ExternalCitation · doi-reference
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA
10.1186/s13073-022-01125-8 · ExternalCitation · doi-reference
Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice
10.1371/journal.pone.0051848 · ExternalCitation · doi-reference
Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer
10.1371/journal.pone.0191231 · ExternalCitation · doi-reference
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