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References from Decreased expression of immune activator WARS1 and other pro-inflammatory mediators in type 1-like macrophages as an associated mode of action in response to fucoidan from marine brown algae. Local targets link to admitted publications; unresolved targets remain external evidence.
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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
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Investigating the anti-inflammatory activity of various brown algae species
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Therapeutic effects of fucoidan: a review on recent studies
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Marine algae: a treasure trove of bioactive anti-inflammatory compounds
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Anti-inflammatory effects of marine bioactive compounds and their potential as functional food ingredients in the prevention and treatment of neuroinflammatory disorders
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Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection
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Anti-inflammatory and neuroprotective effects of Undaria pinnatifida fucoidan
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Optimized and standardized isolation and structural characterization of anti-inflammatory sulfated polysaccharides from the red alga Delesseria sanGuinea (Hudson) Lamouroux (Ceramiales, Delesseriaceae)
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Size distribution and chain conformation of six different fucoidans using size-exclusion chromatography with multiple detection
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Degradation of eight sulfated polysaccharides extracted from red and brown algae and its impact on structure and pharmacological activities
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Gradual degradation of fucoidan from Fucus vesiculosus and its effect on structure, antioxidant and antiproliferative activities
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Integrated bioinformatics analysis and experimental validation reveal the relationship between ALOX5AP and the prognosis and immune microenvironment in glioma
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Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury
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Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
10.1016/j.celrep.2022.111905 · 2023 · External reference
Size-dependent pharmacological activities of differently degraded fucoidan fractions from Fucus vesiculosus
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Macrophage biology in development, homeostasis and disease
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Protective and pathogenic functions of macrophage subsets
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Diversity, mechanisms, and significance of macrophage plasticity
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Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages
10.1165/rcmb.2015-0012oc · 2015 · External reference
A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage
10.5551/jat.11.88 · 2004 · External reference
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary beta-glucan-induced inflammatory adaptation
10.1038/s41590-024-01830-z · 2024 · External reference
LSP1-myosin1e bimolecular complex regulates focal adhesion dynamics and cell migration
10.1096/fj.202000740rr · 2021 · External reference
Classically activated macrophages use stable microtubules for matrix metalloproteinase-9 (MMP-9) secretion
10.1074/jbc.m111.290676 · 2012 · External reference
MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen
10.1067/mva.2001.119401 · 2001 · External reference
Polarization and characterization of M1 and M2 human monocyte-derived macrophages on implant surfaces
10.3791/67180 · 2024 · External reference
IFNgamma: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy
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MIF signal transduction initiated by binding to CD74
10.1084/jem.20030286 · 2003 · External reference
CD74 as a prognostic and M1 macrophage infiltration marker in a comprehensive pan-cancer analysis
10.1038/s41598-024-58899-7 · 2024 · External reference
Aminoacyl-tRNA synthetases as therapeutic targets
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Unique roles of tryptophanyl-tRNA synthetase in immune control and its therapeutic implications
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Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection
10.1038/nmicrobiol.2016.191 · 2016 · External reference
Released tryptophanyl-tRNA synthetase stimulates innate immune responses against viral infection
10.1128/jvi.01291-18 · 2019 · External reference
Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis
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An interferon-induced protein with release factor activity is a tryptophanyl-tRNA synthetase
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Tryptophanyl-transfer RNA synthetase is involved in a negative feedback loop mitigating interferon-gamma-induced gene expression
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Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells
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Macrophages and urokinase plasminogen activator receptor system in multiple myeloma: Case series and literature review
10.3390/ijms241310519 · 2023 · External reference
Urokinase-type plasminogen activator receptor (uPAR) in inflammation and disease: A unique inflammatory pathway activator
10.3390/biomedicines12061167 · 2024 · External reference
The uPA/uPAR system orchestrates the inflammatory response, vascular homeostasis, and immune system in fibrosis progression
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