Research graph
References from Multi-omics reveals regulatory networks and critical early-warning factors for severe disease progression in diabetic patients infected with SARS-CoV-2. Local targets link to admitted publications; unresolved targets remain external evidence.
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
10.1016/s0140-6736(20)30183-5 · 2020 · External reference
Risk factors for Covid-19-related mortality in people with type 1 and type 2 diabetes in England: A population-based cohort study
10.1016/s2213-8587(20)30271-0 · 2020 · External reference
Covid-19 and diabetes: Association intensify risk factors for morbidity and mortality
10.1016/j.biopha.2022.113089 · 2022 · External reference
Continuation versus discontinuation of renin-angiotensin system inhibitors in patients admitted to hospital with Covid-19: A prospective, randomised, open-label trial
10.1016/s2213-2600(20)30558-0 · 2021 · External reference
Respiratory tract infections in diabetes - Lessons from tuberculosis and influenza to guide understanding of Covid-19 severity
10.3389/fendo.2022.919223 · 2022 · External reference
Increasing Hba1c is associated with reduced Cd8(+) T cell functionality in response to influenza virus in a Tcr-dependent manner in individuals with diabetes mellitus
10.1007/s00018-023-05010-4 · 2024 · External reference
Cardiovascular autonomic dysfunction in post-Covid-19 syndrome: A major health-care burden
10.1038/s41569-023-00962-3 · 2024 · External reference
Single-cell transcriptomic analysis reveals a systemic immune dysregulation in Covid-19-associated pediatric encephalopathy
10.1038/s41392-023-01641-y · 2023 · External reference
Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes
10.1038/s41586-023-06803-0 · 2023 · External reference
Covid-19 pandemic: Can fasting plasma glucose and Hba1c replace the oral glucose tolerance test to screen for hyperglycaemia in pregnancy
10.1016/j.diabres.2020.108640 · 2021 · External reference
The global impact of Covid-19 pandemic on the incidence of pediatric new-onset type 1 diabetes and ketoacidosis: A systematic review and meta-analysis
10.1002/jmv.27996 · 2022 · External reference
Diabetes and Covid-19: Risks, management, and learnings from other national disasters
10.2337/dc20-1192 · 2020 · External reference
Healthy plant-based diets improve dyslipidemias, insulin resistance, and inflammation in metabolic syndrome. A narrative review
10.1016/j.advnut.2022.10.002 · 2023 · External reference
Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in Covid-19
10.1126/sciimmunol.adf0348 · 2023 · External reference
Guideline for the prevention and treatment of diabetes mellitus in China (2024 edition)
10.3760/cma.j.cn115791-20241203-00705 · 2025 · External reference
Diagnosis and treatment protocol for Covid-19 patients (Tentative 10th version)
10.1002/hcs2.36 · 2023 · External reference
In-depth serum proteomics atlas of Covid-19 defines a severity-resistance index from a four-protein panel for disease severity and prognosis
10.1186/s12967-026-08172-4 · 2026 · External reference
Proteomics and metabolomics profiles of unvaccinated nonagenarian patients with severe Sars-Cov-2 infection
10.1021/acs.jproteome.5c00251 · 2025 · External reference
Targeting Loxl1-expressing hepatic stellate cell inhibits fibrogenesis and sinusoid angiogenesis via Loxl1/Runx1/Vegfa axis during progression of liver fibrosis
10.1016/j.jcmgh.2025.101637 · 2026 · External reference
Mitcom-based prognostic model identifies Glud1 as a key suppressor of glioblastoma growth and invasion through regulation of mitochondrial structure and metabolism
10.1186/s12935-025-03875-y · 2025 · External reference
Genome-wide DNA methylation profiling after Ayurveda intervention to bronchial asthmatics identifies differential methylation in several transcription factors with immune process related function
10.1016/j.jaim.2023.100692 · 2023 · External reference
Membrane phospholipid remodeling modulates nonalcoholic steatohepatitis progression by regulating mitochondrial homeostasis
10.1097/hep.0000000000000375 · 2024 · External reference
Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration
10.1038/s41556-025-01799-3 · 2025 · External reference
The relationship between adherence to the Mediterranean diet, oxidative stress, trimethylamine N-oxide, and inflammatory markers in patients with metabolic dysfunction-associated steatotic liver disease
10.3390/nu18142231 · 2026 · External reference
Bioactive adipose-derived Ecm hydrogel loaded with cytokine-releasing microspheres promotes spinal cord repair by suppressing inflammation, apoptosis, oxidative stress, and ferroptosis
10.1007/s00418-026-02519-0 · 2026 · External reference
Covid-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis
10.1073/pnas.2217119120 · 2023 · External reference
Hyperglycemia in acute Covid-19 is characterized by insulin resistance and adipose tissue infectivity by Sars-Cov-2
10.1016/j.cmet.2021.09.009 · 2021 · External reference
Clinical characteristics and risk factors for mortality in pulmonary mucormycosis among patients with non-hematologic Malignancies
10.1186/s12890-026-04474-x · 2026 · External reference
Clinical predictors of mortality in severe fever with thrombocytopenia syndrome: An updated systematic review and meta-analysis
10.3390/pathogens15070767 · 2026 · External reference
Patient-level multidimensional response phenotypes in obesity-associated type 2 diabetes: A 12-month real-world cohort study
10.3390/jcm15145671 · 2026 · External reference
Chronic Chagas disease and type 2 diabetes comorbidity. The scenario in which two differently driven inflammatory mechanisms meet
10.1016/j.smim.2026.102028 · 2026 · External reference
Diabetic hyperglycaemia activates Camkii and arrhythmias by O-linked glycosylation
10.1038/nature12537 · 2013 · External reference
Glucosamine links hyperglycemia to Mtorc1 activation and glucose toxicity in diabetes
10.1172/jci.insight.197331 · 2026 · External reference
Pediatric cerebral sinus venous thrombosis during the first three years of the Sars-Cov-2 pandemic: A multinational case series
10.1002/1545-5017.70566 · 2026 · External reference
Crystallization behavior and crystallographic properties of Dl-arabinose and Dl-xylose diastereomer sugars
10.1021/acs.cgd.1c01329 · 2022 · External reference
The Pi3k/Akt signaling networks in cancer glucose metabolism: Mechanisms and therapeutic implications
10.1016/j.tranon.2026.102850 · 2026 · External reference
Analysis of serum fatty acid, amino acid, and organic acid profiles in gestational hypertension and gestational diabetes mellitus via targeted metabolomics
10.3389/fnut.2022.974902 · 2022 · External reference
Tbx1 suppresses colorectal cancer cells via Ppp2r2b-mediated inhibition of Mapk/Erk and Pi3k/Akt pathways
10.1016/j.cellsig.2026.112772 · 2026 · External reference
Empagliflozin, linagliptin, and metformin differentially affect renal Pi3k/Akt and Mapk/Erk signaling pathways in Db/Db diabetic mice
10.3390/ijms27146483 · 2026 · External reference
Machine-learning model for mortality prediction in patients with community-acquired pneumonia: Development and validation study
10.1016/j.chest.2022.07.005 · 2023 · External reference
Modifications to the National Early Warning Score 2: A scoping review
10.1186/s12916-025-03943-0 · 2025 · External reference
Pediatric cerebral sinus venous thrombosis during the first three years of the Sars-Cov-2 pandemic: A multinational case series
10.1002/1545-5017.70566 · ExternalCitation · doi-reference
Diagnosis and treatment protocol for Covid-19 patients (Tentative 10th version)
10.1002/hcs2.36 · ExternalCitation · doi-reference
The global impact of Covid-19 pandemic on the incidence of pediatric new-onset type 1 diabetes and ketoacidosis: A systematic review and meta-analysis
10.1002/jmv.27996 · ExternalCitation · doi-reference
Increasing Hba1c is associated with reduced Cd8(+) T cell functionality in response to influenza virus in a Tcr-dependent manner in individuals with diabetes mellitus
10.1007/s00018-023-05010-4 · ExternalCitation · doi-reference
Bioactive adipose-derived Ecm hydrogel loaded with cytokine-releasing microspheres promotes spinal cord repair by suppressing inflammation, apoptosis, oxidative stress, and ferroptosis
10.1007/s00418-026-02519-0 · ExternalCitation · doi-reference
Healthy plant-based diets improve dyslipidemias, insulin resistance, and inflammation in metabolic syndrome. A narrative review
10.1016/j.advnut.2022.10.002 · ExternalCitation · doi-reference
Covid-19 and diabetes: Association intensify risk factors for morbidity and mortality
10.1016/j.biopha.2022.113089 · ExternalCitation · doi-reference
Tbx1 suppresses colorectal cancer cells via Ppp2r2b-mediated inhibition of Mapk/Erk and Pi3k/Akt pathways
10.1016/j.cellsig.2026.112772 · ExternalCitation · doi-reference
Machine-learning model for mortality prediction in patients with community-acquired pneumonia: Development and validation study
10.1016/j.chest.2022.07.005 · ExternalCitation · doi-reference
Hyperglycemia in acute Covid-19 is characterized by insulin resistance and adipose tissue infectivity by Sars-Cov-2
10.1016/j.cmet.2021.09.009 · ExternalCitation · doi-reference
Covid-19 pandemic: Can fasting plasma glucose and Hba1c replace the oral glucose tolerance test to screen for hyperglycaemia in pregnancy
10.1016/j.diabres.2020.108640 · ExternalCitation · doi-reference
Genome-wide DNA methylation profiling after Ayurveda intervention to bronchial asthmatics identifies differential methylation in several transcription factors with immune process related function
10.1016/j.jaim.2023.100692 · ExternalCitation · doi-reference
Targeting Loxl1-expressing hepatic stellate cell inhibits fibrogenesis and sinusoid angiogenesis via Loxl1/Runx1/Vegfa axis during progression of liver fibrosis
10.1016/j.jcmgh.2025.101637 · ExternalCitation · doi-reference
Chronic Chagas disease and type 2 diabetes comorbidity. The scenario in which two differently driven inflammatory mechanisms meet
10.1016/j.smim.2026.102028 · ExternalCitation · doi-reference
The Pi3k/Akt signaling networks in cancer glucose metabolism: Mechanisms and therapeutic implications
10.1016/j.tranon.2026.102850 · ExternalCitation · doi-reference
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
10.1016/s0140-6736(20)30183-5 · ExternalCitation · doi-reference
Continuation versus discontinuation of renin-angiotensin system inhibitors in patients admitted to hospital with Covid-19: A prospective, randomised, open-label trial
10.1016/s2213-2600(20)30558-0 · ExternalCitation · doi-reference
Risk factors for Covid-19-related mortality in people with type 1 and type 2 diabetes in England: A population-based cohort study
10.1016/s2213-8587(20)30271-0 · ExternalCitation · doi-reference
Crystallization behavior and crystallographic properties of Dl-arabinose and Dl-xylose diastereomer sugars
10.1021/acs.cgd.1c01329 · ExternalCitation · doi-reference
Proteomics and metabolomics profiles of unvaccinated nonagenarian patients with severe Sars-Cov-2 infection
10.1021/acs.jproteome.5c00251 · ExternalCitation · doi-reference
Diabetic hyperglycaemia activates Camkii and arrhythmias by O-linked glycosylation
10.1038/nature12537 · ExternalCitation · doi-reference
Single-cell transcriptomic analysis reveals a systemic immune dysregulation in Covid-19-associated pediatric encephalopathy
10.1038/s41392-023-01641-y · ExternalCitation · doi-reference
Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration
10.1038/s41556-025-01799-3 · ExternalCitation · doi-reference
Cardiovascular autonomic dysfunction in post-Covid-19 syndrome: A major health-care burden
10.1038/s41569-023-00962-3 · ExternalCitation · doi-reference
Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes
10.1038/s41586-023-06803-0 · ExternalCitation · doi-reference
Covid-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis
10.1073/pnas.2217119120 · ExternalCitation · doi-reference
Membrane phospholipid remodeling modulates nonalcoholic steatohepatitis progression by regulating mitochondrial homeostasis
10.1097/hep.0000000000000375 · ExternalCitation · doi-reference
Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in Covid-19
10.1126/sciimmunol.adf0348 · ExternalCitation · doi-reference
Glucosamine links hyperglycemia to Mtorc1 activation and glucose toxicity in diabetes
10.1172/jci.insight.197331 · ExternalCitation · doi-reference
Clinical characteristics and risk factors for mortality in pulmonary mucormycosis among patients with non-hematologic Malignancies
10.1186/s12890-026-04474-x · ExternalCitation · doi-reference
Modifications to the National Early Warning Score 2: A scoping review
10.1186/s12916-025-03943-0 · ExternalCitation · doi-reference
Mitcom-based prognostic model identifies Glud1 as a key suppressor of glioblastoma growth and invasion through regulation of mitochondrial structure and metabolism
10.1186/s12935-025-03875-y · ExternalCitation · doi-reference
In-depth serum proteomics atlas of Covid-19 defines a severity-resistance index from a four-protein panel for disease severity and prognosis
10.1186/s12967-026-08172-4 · ExternalCitation · doi-reference
Diabetes and Covid-19: Risks, management, and learnings from other national disasters
10.2337/dc20-1192 · ExternalCitation · doi-reference
Respiratory tract infections in diabetes - Lessons from tuberculosis and influenza to guide understanding of Covid-19 severity
10.3389/fendo.2022.919223 · ExternalCitation · doi-reference
Analysis of serum fatty acid, amino acid, and organic acid profiles in gestational hypertension and gestational diabetes mellitus via targeted metabolomics
10.3389/fnut.2022.974902 · ExternalCitation · doi-reference
Empagliflozin, linagliptin, and metformin differentially affect renal Pi3k/Akt and Mapk/Erk signaling pathways in Db/Db diabetic mice
10.3390/ijms27146483 · ExternalCitation · doi-reference
Patient-level multidimensional response phenotypes in obesity-associated type 2 diabetes: A 12-month real-world cohort study
10.3390/jcm15145671 · ExternalCitation · doi-reference
The relationship between adherence to the Mediterranean diet, oxidative stress, trimethylamine N-oxide, and inflammatory markers in patients with metabolic dysfunction-associated steatotic liver disease
10.3390/nu18142231 · ExternalCitation · doi-reference
Clinical predictors of mortality in severe fever with thrombocytopenia syndrome: An updated systematic review and meta-analysis
10.3390/pathogens15070767 · ExternalCitation · doi-reference
Guideline for the prevention and treatment of diabetes mellitus in China (2024 edition)
10.3760/cma.j.cn115791-20241203-00705 · ExternalCitation · doi-reference
