Research graph
References from Hub circRNAs in cancer: dual regulation of metastasis and immune evasion. Local targets link to admitted publications; unresolved targets remain external evidence.
Aberrant pre-mRNA processing in cancer
10.1084/jem.20230891 · 2024 · External reference
Steering research on mRNA splicing in cancer towards clinical translation
10.1038/s41568-024-00750-2 · 2024 · External reference
The many roads from alternative splicing to cancer: Molecular mechanisms involving driver genes
10.3390/cancers16112123 · 2024 · External reference
Nonsense-mediated mRNA decay: a key regulatory system engaged in cancer
10.1186/s12964-025-02503-6 · 2025 · External reference
Insights into circular RNA biology
10.1080/15476286.2016.1271524 · 2017 · External reference
Insights into the role of CircRNAs: Biogenesis, characterization, functional, and clinical impact in human Malignancies
10.3389/fcell.2021.617281 · 2021 · External reference
The emerging roles and functions of circular RNAs and their generation
10.1186/s12929-019-0523-z · 2019 · External reference
New insight into circRNAs: characterization, strategies, and biomedical applications
10.1186/s40164-023-00451-w · 2023 · External reference
Emerging roles of CircRNA-miRNA networks in cancer development and therapeutic response
10.1016/j.ncrna.2024.09.006 · 2025 · External reference
Mechanisms and therapeutic implications of gene expression regulation by circRNA-protein interactions in cancer
10.1038/s42003-024-07383-z · 2025 · External reference
State-of-the-art strategies for circular RNA in cancers: Opportunity and challenge
10.1002/mco2.70608 · 2026 · External reference
Circ_0089761 accelerates colorectal cancer metastasis and immune escape via miR-27b-3p/PD-L1 axis
10.14814/phy2.70137 · 2024 · External reference
Toward precision oncology: deciphering the circRNA-EMT axis in cancer and its therapeutic implications
10.1080/15476286.2026.2639611 · 2026 · External reference
Circular RNAs: Emerging regulators of signaling pathways in epithelial-mesenchymal transition and angiogenesis during breast cancer progression
10.1016/j.seminoncol.2025.152340 · 2025 · External reference
Circular RNAs: key players in tumor immune evasion
10.1007/s11010-024-05186-8 · 2025 · External reference
Novel insights into the role of circRNAs in cancer immunotherapy resistance and clinical implications
10.3390/ijms27083678 · 2026 · External reference
CircRNAs in the tumor microenvironment: new frontiers in cancer progression and therapy
10.1016/j.critrevonc.2025.104754 · 2025 · External reference
Molecular basis of backsplicing regulation and its application to manipulate circRNA levels
10.1080/15476286.2025.2525914 · 2025 · External reference
The emerging roles of circRNAs in cancer and oncology
10.1038/s41571-021-00585-y · 2022 · External reference
Complementary sequence-mediated exon circularization
10.1016/j.cell.2014.09.001 · 2014 · External reference
EIciRNAs in focus: current understanding and future perspectives
10.1080/15476286.2024.2443876 · 2025 · External reference
Systematic identification and characterization of exon-intron circRNAs
10.1101/gr.278590.123 · 2024 · External reference
Intron lariat spliceosomes convert lariats to true circles: implications for intron transposition
10.1101/gad.351764.124 · 2024 · External reference
Features and biomedical relevance of circular RNA biogenesis
10.1016/j.tig.2025.11.001 · 2026 · External reference
Molecular mechanisms of circular RNA translation
10.1038/s12276-024-01220-3 · 2024 · External reference
Circular RNAs acting as miRNAs' sponges and their roles in stem cells
10.3390/jcm11102909 · 2022 · External reference
Circular RNA in cancer
10.1038/s41568-024-00721-7 · 2024 · External reference
Going circular: history, present, and future of circRNAs in cancer
10.1038/s41388-023-02780-w · 2023 · External reference
A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs
10.1101/gad.314856.118 · 2018 · External reference
Functional roles of conserved lncRNAs and circRNAs in eukaryotes
10.1016/j.ncrna.2024.06.014 · 2024 · External reference
CircRNA in cancer: Fundamental mechanism and clinical potential
10.1016/j.canlet.2021.02.004 · 2021 · External reference
Wet lab techniques for the functional analysis of circular RNA
10.3390/cells14231920 · 2025 · External reference
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11
10.1186/s12943-025-02261-6 · 2025 · External reference
CircTRIM1 encodes TRIM1-269aa to promote chemoresistance and metastasis of TNBC via enhancing CaM-dependent MARCKS translocation and PI3K/AKT/mTOR activation
10.1186/s12943-024-02019-6 · 2024 · External reference
Multi-stage mechanisms of tumor metastasis and therapeutic strategies
10.1038/s41392-024-01955-5 · 2024 · External reference
Unlocking the potential of extracellular vesicle circRNAs in breast cancer: From molecular mechanisms to therapeutic horizons
10.1016/j.biopha.2024.117480 · 2024 · External reference
CircRNA ciRS-7: a novel oncogene in multiple cancers
10.7150/ijbs.54292 · 2021 · External reference
Circular RNA CDR1as/ciRS-7- a novel biomarker in solid tumors
10.3389/fonc.2024.1468363 · 2024 · External reference
Circ_CDR1as: a circular RNA with roles in the carcinogenesis
10.1016/j.prp.2022.153968 · 2022 · External reference
CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value
10.2147/cmar.s178213 · 2018 · External reference
Alternative splicing in EMT and TGF-β signaling during cancer progression
10.1016/j.semcancer.2024.04.001 · 2024 · External reference
Circular RNA ciRS-7 inhibits autophagy of ESCC cells by functioning as miR-1299 sponge to target EGFR signaling
10.1002/jcb.29339 · 2020 · External reference
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways
10.1016/j.yexcr.2020.112290 · 2020 · External reference
TGF-β signaling promotes cervical cancer metastasis via CDR1as
10.1186/s12943-023-01743-9 · 2023 · External reference
Circular RNA HIPK3 mediates epithelial-mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs
10.1038/s41598-024-71119-6 · 2024 · External reference
A concise review on the role of CircPVT1 in tumorigenesis, drug sensitivity, and cancer prognosis
10.3389/fonc.2021.762960 · 2021 · External reference
Functional roles and mechanisms of circRNA-protein interactions in cancer progression and tumor immune regulation
10.3389/fimmu.2026.1771949 · 2026 · External reference
A circular RNA promotes tumor metastasis through stabilizing MSI2 protein in pancreatic ductal adenocarcinoma
10.34133/research.0918 · 2025 · External reference
CircSATB1 promotes colorectal cancer liver metastasis through facilitating FKBP8 degradation via RNF25-mediated ubiquitination
10.1002/advs.202406962 · 2025 · External reference
The GAUGAA motif is responsible for the binding between circSMARCA5 and SRSF1 and related downstream effects on glioblastoma multiforme cell migration and angiogenic potential
10.3390/ijms22041678 · 2021 · External reference
RBM24-mediated biogenesis of circ23679 protects cardiomyocytes against apoptosis via sponging miR-15b-5p
10.1016/j.ijbiomac.2025.143242 · 2025 · External reference
circTGFBR2(3-6) acts as an assembly platform for RNA-binding protein IGF2BP3 and TGFBR1 mRNA to enhance breast cancer cell plasticity
10.1038/s41418-025-01597-2 · 2026 · External reference
A circular RNA activated by TGFβ promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stability
10.1038/s41467-023-42571-1 · 2023 · External reference
Mechanisms and prospects of circular RNAs and their interacting signaling pathways in colorectal cancer
10.3389/fonc.2022.949656 · 2022 · External reference
Circular RNAs as the pivotal regulators of epithelial-mesenchymal transition in gastrointestinal tumor cells
10.1016/j.prp.2023.154472 · 2023 · External reference
Advances in the roles and molecular mechanisms of exosomal circular RNAs in regulating the pre-metastatic niche of tumors
10.1007/s12672-025-02374-w · 2025 · External reference
Hypoxia induced exosomal Circ-ZNF609 promotes pre-metastatic niche formation and cancer progression via miR-150-5p/VEGFA and HuR/ZO-1 axes in esophageal squamous cell carcinoma
10.1038/s41420-024-01905-8 · 2024 · External reference
Targeting circ-0034880-enriched tumor extracellular vesicles to impede SPP1(high)CD206(+) pro-tumor macrophages mediated pre-metastatic niche formation in colorectal cancer liver metastasis
10.1186/s12943-024-02086-9 · 2024 · External reference
Extracellular vesicle-mediated transmission of circPDLIM5 promotes lymphatic metastasis in prostate cancer
10.1186/s13046-025-03443-2 · 2025 · External reference
Circular RNAs as central regulators of metabolic reprogramming and immune responses in the breast cancer microenvironment: A comprehensive review
10.1016/j.biopha.2025.118682 · 2025 · External reference
127aa encoded by circSpdyA promotes FA synthesis and NK cell repression in breast cancers
10.1038/s41418-024-01396-1 · 2025 · External reference
Mechanisms and therapeutic implications of ncRNAs in regulating the PD-1/PD-L1 axis across cancers
10.2174/0113862073384743250617062430 · 2026 · External reference
Circular RNA CDYL facilitates hepatocellular carcinoma stemness and PD-L1(+) exosomes-mediated immunotherapy resistance via stabilizing hornerin protein by blocking synoviolin 1-mediated ubiquitination
10.1016/j.ijbiomac.2025.143246 · 2025 · External reference
Circular RNA circ_0000284 plays an oncogenic role in the progression of non-small cell lung cancer through the miR-377-3p-mediated PD-L1 promotion
10.1186/s12935-020-01310-y · 2020 · External reference
CircNF1 modulates the progression and immune evasion of esophageal squamous cell carcinoma through dual regulation of PD-L1
10.1186/s11658-025-00712-y · 2025 · External reference
CircENTPD7 affects the immune escape of non‐small cell lung cancer cells by modulating the IGF2BP2/PD‐L1 axis
10.3892/ol.2024.14858 · 2025 · External reference
Harnessing the immune system by targeting immune checkpoints: Providing new hope for Oncotherapy
10.3389/fimmu.2022.982026 · 2022 · External reference
N6-methyladenosine-modified circular RNA QSOX1 promotes colorectal cancer resistance to anti-CTLA-4 therapy through induction of intratumoral regulatory T cells
10.1016/j.drup.2022.100886 · 2022 · External reference
circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma
10.1038/s41419-020-2230-9 · 2020 · External reference
Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
10.1186/s12943-023-01759-1 · 2023 · External reference
Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma
10.1186/s12943-020-01222-5 · 2020 · External reference
Circular RNA circSnx5 controls immunogenicity of dendritic cells through the miR-544/SOCS1 axis and PU.1 activity regulation
10.1016/j.ymthe.2020.07.001 · 2020 · External reference
Tumor cell-intrinsic circular RNA circFNDC3B attenuates CD8(+) T cells infiltration in non-small cell lung cancer
10.1038/s42003-025-08108-6 · 2025 · External reference
The molecular landscape of T cell exhaustion in the tumor microenvironment and reinvigoration strategies
10.1080/08830185.2024.2401352 · 2024 · External reference
Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells
10.4049/jimmunol.177.2.896 · 2006 · External reference
Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer
10.1038/s41388-025-03627-2 · 2025 · External reference
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells
10.1111/cas.15365 · 2022 · External reference
Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma
10.1186/s12943-020-01191-9 · 2020 · External reference
circ_0004140 promotes LUAD tumor progression and immune resistance through circ_0004140/miR-1184/CCL22 axis
10.1038/s41420-022-00983-w · 2022 · External reference
Immunoregulatory role of exosomal circRNAs in the tumor microenvironment
10.3389/fonc.2025.1453786 · 2025 · External reference
Exosomal circular RNAs in tumor microenvironment: An emphasis on signaling pathways and clinical opportunities
10.1002/mco2.70019 · 2024 · External reference
Role of circular RNAs in regulating tumor microenvironment, epithelial mesenchymal transition, and resistance to cancer therapy
10.1016/j.critrevonc.2025.104942 · 2025 · External reference
Targeting the circC16orf62/miR-1299/PHF8 axis to suppress metastasis and overcome immune evasion in triple-negative breast cancer
10.1016/j.biopha.2026.119392 · 2026 · External reference
CircLRBA promotes epithelial-mesenchymal transition, immune evasion, chemoimmunotherapy resistance and metastasis through stabilizing Twist1
10.1002/advs.202508918 · 2025 · External reference
What role does PDL1 play in EMT changes in tumors and fibrosis
10.3389/fimmu.2023.1226038 · 2023 · External reference
The binding of PD-L1 and Akt facilitates glioma cell invasion upon starvation via Akt/Autophagy/F-Actin signaling
10.3389/fonc.2019.01347 · 2019 · External reference
Circular RNA hsa_circ_0067842 facilitates tumor metastasis and immune escape in breast cancer through HuR/CMTM6/PD-L1 axis
10.1186/s13062-023-00397-3 · 2023 · External reference
Abstract P5-07-12: Circular RNA NCAPG promotes breast cancer metastasis through acting as the sponge of miR-200s
10.1158/1538-7445.sabcs18-p5-07-12 · 2019 · External reference
CircNSD2 promotes metastasis and immune escape by increasing the USP10/SRSF6-mediated alternative splicing of TPM1 in TNBC
10.1186/s12943-026-02627-4 · 2026 · External reference
Hypoxic exosomal circPLEKHM1-mediated crosstalk between tumor cells and macrophages drives lung cancer metastasis
10.1002/advs.202309857 · 2024 · External reference
Exosomal Circsafb2 reshaping tumor environment to promote renal cell carcinoma progression by mediating M2 macrophage polarization
10.3389/fonc.2022.808888 · 2022 · External reference
The crosstalk and clinical implications of circRNAs and glucose metabolism in gastrointestinal cancers
10.3390/cancers15082229 · 2023 · External reference
Lactate metabolic reprogramming mediated by circRNA-LDHA complex facilitates innate immune evasion of liver cancer
10.1002/advs.202509989 · 2025 · External reference
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma
10.1186/s12931-023-02563-7 · 2023 · External reference
CircRUNX1 enhances the Warburg effect and immune evasion in non-small cell lung cancer through the miR-145/HK2 pathway
10.1016/j.canlet.2025.217639 · 2025 · External reference
The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment
10.1038/s41467-024-55577-0 · 2025 · External reference
Best practices to ensure robust investigation of circular RNAs: pitfalls and tips
10.15252/embr.202052072 · 2021 · External reference
Assessing the impacts of various factors on circular RNA reliability
10.26508/lsa.202201793 · 2023 · External reference
Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs
10.1186/s13059-021-02263-9 · 2021 · External reference
Circulating liquid biopsy biomarkers in glioblastoma: advances and challenges
10.3390/ijms25147974 · 2024 · External reference
Identification of circRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy
10.1038/s41467-023-38232-y · 2023 · External reference
The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy
10.7150/thno.64096 · 2022 · External reference
CircRNA knockout/knockdown tools in molecular biology research
10.1016/j.bbrc.2025.152607 · 2025 · External reference
Synergistic immunoregulation: harnessing circRNAs and piRNAs to amplify PD-1/PD-L1 inhibition therapy
10.2147/ijn.s461289 · 2024 · External reference
The circular RNA circFGFR4 facilitates resistance to anti-PD-1 of triple-negative breast cancer by targeting the miR-185-5p/CXCR4 axis
10.2147/cmar.s411901 · 2023 · External reference
Tumour circular RNAs elicit anti-tumour immunity by encoding cryptic peptides
10.1038/s41586-023-06834-7 · 2024 · External reference
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
10.1002/jev2.12404 · 2024 · External reference
MIQE 2.0: Revision of the minimum information for publication of quantitative real-time PCR experiments guidelines
10.1093/clinchem/hvaf043 · 2025 · External reference
How laboratory guidelines promote the validity of circulating extracellular vesicle-associated nucleic acid biomarker signatures in liquid biopsy
10.3390/ijms262412115 · 2025 · External reference
Circular RNA vaccine in disease prevention and treatment
10.1038/s41392-023-01561-x · 2023 · External reference
Hypoxic exosomal circPLEKHM1-mediated crosstalk between tumor cells and macrophages drives lung cancer metastasis
10.1002/advs.202309857 · ExternalCitation · doi-reference
CircSATB1 promotes colorectal cancer liver metastasis through facilitating FKBP8 degradation via RNF25-mediated ubiquitination
10.1002/advs.202406962 · ExternalCitation · doi-reference
CircLRBA promotes epithelial-mesenchymal transition, immune evasion, chemoimmunotherapy resistance and metastasis through stabilizing Twist1
10.1002/advs.202508918 · ExternalCitation · doi-reference
Lactate metabolic reprogramming mediated by circRNA-LDHA complex facilitates innate immune evasion of liver cancer
10.1002/advs.202509989 · ExternalCitation · doi-reference
Circular RNA ciRS-7 inhibits autophagy of ESCC cells by functioning as miR-1299 sponge to target EGFR signaling
10.1002/jcb.29339 · ExternalCitation · doi-reference
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
10.1002/jev2.12404 · ExternalCitation · doi-reference
Exosomal circular RNAs in tumor microenvironment: An emphasis on signaling pathways and clinical opportunities
10.1002/mco2.70019 · ExternalCitation · doi-reference
State-of-the-art strategies for circular RNA in cancers: Opportunity and challenge
10.1002/mco2.70608 · ExternalCitation · doi-reference
Circular RNAs: key players in tumor immune evasion
10.1007/s11010-024-05186-8 · ExternalCitation · doi-reference
Advances in the roles and molecular mechanisms of exosomal circular RNAs in regulating the pre-metastatic niche of tumors
10.1007/s12672-025-02374-w · ExternalCitation · doi-reference
CircRNA knockout/knockdown tools in molecular biology research
10.1016/j.bbrc.2025.152607 · ExternalCitation · doi-reference
Unlocking the potential of extracellular vesicle circRNAs in breast cancer: From molecular mechanisms to therapeutic horizons
10.1016/j.biopha.2024.117480 · ExternalCitation · doi-reference
Circular RNAs as central regulators of metabolic reprogramming and immune responses in the breast cancer microenvironment: A comprehensive review
10.1016/j.biopha.2025.118682 · ExternalCitation · doi-reference
Targeting the circC16orf62/miR-1299/PHF8 axis to suppress metastasis and overcome immune evasion in triple-negative breast cancer
10.1016/j.biopha.2026.119392 · ExternalCitation · doi-reference
CircRNA in cancer: Fundamental mechanism and clinical potential
10.1016/j.canlet.2021.02.004 · ExternalCitation · doi-reference
CircRUNX1 enhances the Warburg effect and immune evasion in non-small cell lung cancer through the miR-145/HK2 pathway
10.1016/j.canlet.2025.217639 · ExternalCitation · doi-reference
Complementary sequence-mediated exon circularization
10.1016/j.cell.2014.09.001 · ExternalCitation · doi-reference
CircRNAs in the tumor microenvironment: new frontiers in cancer progression and therapy
10.1016/j.critrevonc.2025.104754 · ExternalCitation · doi-reference
Role of circular RNAs in regulating tumor microenvironment, epithelial mesenchymal transition, and resistance to cancer therapy
10.1016/j.critrevonc.2025.104942 · ExternalCitation · doi-reference
N6-methyladenosine-modified circular RNA QSOX1 promotes colorectal cancer resistance to anti-CTLA-4 therapy through induction of intratumoral regulatory T cells
10.1016/j.drup.2022.100886 · ExternalCitation · doi-reference
RBM24-mediated biogenesis of circ23679 protects cardiomyocytes against apoptosis via sponging miR-15b-5p
10.1016/j.ijbiomac.2025.143242 · ExternalCitation · doi-reference
Circular RNA CDYL facilitates hepatocellular carcinoma stemness and PD-L1(+) exosomes-mediated immunotherapy resistance via stabilizing hornerin protein by blocking synoviolin 1-mediated ubiquitination
10.1016/j.ijbiomac.2025.143246 · ExternalCitation · doi-reference
Functional roles of conserved lncRNAs and circRNAs in eukaryotes
10.1016/j.ncrna.2024.06.014 · ExternalCitation · doi-reference
Emerging roles of CircRNA-miRNA networks in cancer development and therapeutic response
10.1016/j.ncrna.2024.09.006 · ExternalCitation · doi-reference
Circ_CDR1as: a circular RNA with roles in the carcinogenesis
10.1016/j.prp.2022.153968 · ExternalCitation · doi-reference
Circular RNAs as the pivotal regulators of epithelial-mesenchymal transition in gastrointestinal tumor cells
10.1016/j.prp.2023.154472 · ExternalCitation · doi-reference
Alternative splicing in EMT and TGF-β signaling during cancer progression
10.1016/j.semcancer.2024.04.001 · ExternalCitation · doi-reference
Circular RNAs: Emerging regulators of signaling pathways in epithelial-mesenchymal transition and angiogenesis during breast cancer progression
10.1016/j.seminoncol.2025.152340 · ExternalCitation · doi-reference
Features and biomedical relevance of circular RNA biogenesis
10.1016/j.tig.2025.11.001 · ExternalCitation · doi-reference
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways
10.1016/j.yexcr.2020.112290 · ExternalCitation · doi-reference
Circular RNA circSnx5 controls immunogenicity of dendritic cells through the miR-544/SOCS1 axis and PU.1 activity regulation
10.1016/j.ymthe.2020.07.001 · ExternalCitation · doi-reference
Molecular mechanisms of circular RNA translation
10.1038/s12276-024-01220-3 · ExternalCitation · doi-reference
Going circular: history, present, and future of circRNAs in cancer
10.1038/s41388-023-02780-w · ExternalCitation · doi-reference
Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer
10.1038/s41388-025-03627-2 · ExternalCitation · doi-reference
Circular RNA vaccine in disease prevention and treatment
10.1038/s41392-023-01561-x · ExternalCitation · doi-reference
Multi-stage mechanisms of tumor metastasis and therapeutic strategies
10.1038/s41392-024-01955-5 · ExternalCitation · doi-reference
127aa encoded by circSpdyA promotes FA synthesis and NK cell repression in breast cancers
10.1038/s41418-024-01396-1 · ExternalCitation · doi-reference
circTGFBR2(3-6) acts as an assembly platform for RNA-binding protein IGF2BP3 and TGFBR1 mRNA to enhance breast cancer cell plasticity
10.1038/s41418-025-01597-2 · ExternalCitation · doi-reference
circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma
10.1038/s41419-020-2230-9 · ExternalCitation · doi-reference
circ_0004140 promotes LUAD tumor progression and immune resistance through circ_0004140/miR-1184/CCL22 axis
10.1038/s41420-022-00983-w · ExternalCitation · doi-reference
Hypoxia induced exosomal Circ-ZNF609 promotes pre-metastatic niche formation and cancer progression via miR-150-5p/VEGFA and HuR/ZO-1 axes in esophageal squamous cell carcinoma
10.1038/s41420-024-01905-8 · ExternalCitation · doi-reference
Identification of circRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy
10.1038/s41467-023-38232-y · ExternalCitation · doi-reference
A circular RNA activated by TGFβ promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stability
10.1038/s41467-023-42571-1 · ExternalCitation · doi-reference
The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment
10.1038/s41467-024-55577-0 · ExternalCitation · doi-reference
Circular RNA in cancer
10.1038/s41568-024-00721-7 · ExternalCitation · doi-reference
Steering research on mRNA splicing in cancer towards clinical translation
10.1038/s41568-024-00750-2 · ExternalCitation · doi-reference
The emerging roles of circRNAs in cancer and oncology
10.1038/s41571-021-00585-y · ExternalCitation · doi-reference
Tumour circular RNAs elicit anti-tumour immunity by encoding cryptic peptides
10.1038/s41586-023-06834-7 · ExternalCitation · doi-reference
Circular RNA HIPK3 mediates epithelial-mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs
10.1038/s41598-024-71119-6 · ExternalCitation · doi-reference
Mechanisms and therapeutic implications of gene expression regulation by circRNA-protein interactions in cancer
10.1038/s42003-024-07383-z · ExternalCitation · doi-reference
Tumor cell-intrinsic circular RNA circFNDC3B attenuates CD8(+) T cells infiltration in non-small cell lung cancer
10.1038/s42003-025-08108-6 · ExternalCitation · doi-reference
The molecular landscape of T cell exhaustion in the tumor microenvironment and reinvigoration strategies
10.1080/08830185.2024.2401352 · ExternalCitation · doi-reference
Insights into circular RNA biology
10.1080/15476286.2016.1271524 · ExternalCitation · doi-reference
EIciRNAs in focus: current understanding and future perspectives
10.1080/15476286.2024.2443876 · ExternalCitation · doi-reference
Molecular basis of backsplicing regulation and its application to manipulate circRNA levels
10.1080/15476286.2025.2525914 · ExternalCitation · doi-reference
Toward precision oncology: deciphering the circRNA-EMT axis in cancer and its therapeutic implications
10.1080/15476286.2026.2639611 · ExternalCitation · doi-reference
Aberrant pre-mRNA processing in cancer
10.1084/jem.20230891 · ExternalCitation · doi-reference
MIQE 2.0: Revision of the minimum information for publication of quantitative real-time PCR experiments guidelines
10.1093/clinchem/hvaf043 · ExternalCitation · doi-reference
A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs
10.1101/gad.314856.118 · ExternalCitation · doi-reference
Intron lariat spliceosomes convert lariats to true circles: implications for intron transposition
10.1101/gad.351764.124 · ExternalCitation · doi-reference
Systematic identification and characterization of exon-intron circRNAs
10.1101/gr.278590.123 · ExternalCitation · doi-reference
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells
10.1111/cas.15365 · ExternalCitation · doi-reference
Abstract P5-07-12: Circular RNA NCAPG promotes breast cancer metastasis through acting as the sponge of miR-200s
10.1158/1538-7445.sabcs18-p5-07-12 · ExternalCitation · doi-reference
CircNF1 modulates the progression and immune evasion of esophageal squamous cell carcinoma through dual regulation of PD-L1
10.1186/s11658-025-00712-y · ExternalCitation · doi-reference
The emerging roles and functions of circular RNAs and their generation
10.1186/s12929-019-0523-z · ExternalCitation · doi-reference
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma
10.1186/s12931-023-02563-7 · ExternalCitation · doi-reference
Circular RNA circ_0000284 plays an oncogenic role in the progression of non-small cell lung cancer through the miR-377-3p-mediated PD-L1 promotion
10.1186/s12935-020-01310-y · ExternalCitation · doi-reference
Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma
10.1186/s12943-020-01191-9 · ExternalCitation · doi-reference
Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma
10.1186/s12943-020-01222-5 · ExternalCitation · doi-reference
TGF-β signaling promotes cervical cancer metastasis via CDR1as
10.1186/s12943-023-01743-9 · ExternalCitation · doi-reference
Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
10.1186/s12943-023-01759-1 · ExternalCitation · doi-reference
CircTRIM1 encodes TRIM1-269aa to promote chemoresistance and metastasis of TNBC via enhancing CaM-dependent MARCKS translocation and PI3K/AKT/mTOR activation
10.1186/s12943-024-02019-6 · ExternalCitation · doi-reference
Targeting circ-0034880-enriched tumor extracellular vesicles to impede SPP1(high)CD206(+) pro-tumor macrophages mediated pre-metastatic niche formation in colorectal cancer liver metastasis
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CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11
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