Research graph
References from T cell exhaustion in parasitic infections. Local targets link to admitted publications; unresolved targets remain external evidence.
Viral immune evasion due to persistence of activated T cells without effector function
10.1084/jem.188.12.2205 · 1998 · External reference
Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
10.1084/jem.187.9.1383 · 1998 · External reference
T-cell exhaustion in HIV infection
10.1111/imr.12823 · 2019 · External reference
CD8+ T cell exhaustion and cancer immunotherapy
10.1016/j.canlet.2022.216043 · 2023 · External reference
Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer
10.1016/j.ccell.2024.11.005 · 2024 · External reference
T-cell exhaustion in multiple myeloma
10.1080/17474086.2024.2370552 · 2024 · External reference
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer
10.1016/j.cmet.2022.11.013 · 2023 · External reference
T-cell exhaustion in COVID-19: what do we know
10.3389/fimmu.2025.1678149 · 2025 · External reference
Integrated single-cell transcriptome and T cell receptor profiling reveals defects of T cell exhaustion in pulmonary tuberculosis
10.1016/j.jinf.2024.106158 · 2024 · External reference
Guidelines for T cell nomenclature
10.1038/s41577-025-01238-2 · 2026 · External reference
T cell exhaustion
10.1038/ni.2035 · 2011 · External reference
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
10.1128/jvi.77.8.4911-4927.2003 · 2003 · External reference
Redefining chronic viral infection
10.1016/j.cell.2009.06.036 · 2009 · External reference
T-cell exhaustion: characteristics, causes and conversion
10.1111/j.1365-2567.2010.03255.x · 2010 · External reference
Cellular and molecular mechanisms of CD8+ T cell differentiation, dysfunction and exhaustion
10.3390/ijms21197357 · 2020 · External reference
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
10.1016/j.immuni.2007.09.006 · 2007 · External reference
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection
10.1128/jvi.02524-08 · 2009 · External reference
Inhibitory pattern recognition receptors
10.1084/jem.20211463 · 2022 · External reference
Inhibitory receptors on lymphocytes: insights from infections
10.4049/jimmunol.1100038 · 2012 · External reference
Cell surface signaling molecules in the control of immune responses: a tide model
10.1016/j.immuni.2011.04.008 · 2011 · External reference
Targeting T cell exhaustion: emerging strategies in non-small cell lung cancer
10.3389/fimmu.2024.1507501 · 2024 · External reference
Neoadjuvant PD-1 and LAG-3-targeting bispecific antibody and other immune checkpoint inhibitor combinations in resectable melanoma: the randomized phase 1b/2 Morpheus-Melanoma trial
10.1038/s41591-025-03967-2 · 2025 · External reference
The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial
10.1038/s41591-023-02593-0 · 2023 · External reference
Homeostasis of naive and memory T lymphocytes
10.1101/cshperspect.a037879 · 2021 · External reference
The basis of distinctive IL-2- and IL-15-dependent signaling: weak CD122-dependent signaling favors CD8+ T central-memory cell survival but not T effector-memory cell development
10.4049/jimmunol.1003961 · 2011 · External reference
Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice
10.1084/jem.20061871 · 2007 · External reference
Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection
10.1084/jem.20061937 · 2007 · External reference
Antigen-independent memory CD8 T cells do not develop during chronic viral infection
10.1073/pnas.0407192101 · 2004 · External reference
Exhausted PD-1+ TOX+ CD8+ T cells arise only in long-term experimental Trypanosoma cruzi infection
10.3389/fimmu.2022.866179 · 2022 · External reference
TOX is a critical regulator of tumour-specific T cell differentiation
10.1038/s41586-019-1324-y · 2019 · External reference
Metabolic dynamics instruct CD8+ T-cell differentiation and functions
10.1002/eji.202149486 · 2022 · External reference
Guardians of silence: transcriptional networks in T cell quiescence
10.1038/s12276-025-01516-y · 2025 · External reference
Enhanced fatty acid oxidation by selective activation of PPARα alleviates autoimmunity through metabolic transformation in T-cells
10.1016/j.clim.2024.110357 · 2024 · External reference
Oxidative and glycolytic metabolism: their reciprocal regulation and dysregulation in cancer
10.3390/cells14151177 · 2025 · External reference
Energy metabolism in health and diseases
10.1038/s41392-025-02141-x · 2025 · External reference
T cell metabolism drives immunity
10.1084/jem.20151159 · 2015 · External reference
CD8+ T cell metabolism in infection and cancer
10.1038/s41577-021-00537-8 · 2021 · External reference
Exhausted CD8 + T cell in HIV infection exhibits an impaired bioenergetic metabolism driven by mitochondrial dysfunction
10.1111/imm.70054 · 2026 · External reference
Metabolic reprogramming in cancer: implications for immunosuppressive microenvironment
10.1111/imm.13871 · 2025 · External reference
Targeting pyruvate metabolism generates distinct CD8+ T cell responses to gammaherpesvirus and B lymphoma
10.1172/jci.insight.187680 · 2025 · External reference
Upregulation of CD244 promotes CD8+ T cell exhaustion in patients with alveolar echinococcosis and a murine model
10.1186/s13071-024-06573-2 · 2024 · External reference
Exhausted CD4+ T cells during malaria exhibit reduced mTORc1 activity correlated with loss of T-bet expression
10.4049/jimmunol.2000450 · 2020 · External reference
Leishmania mediated regulation of host metabolism: impact on host immunity
10.3389/fimmu.2026.1750304 · 2026 · External reference
Does endoplasmic reticulum (ER) stress contribute to T-cell exhaustion in B-ALL
10.22034/iji.2025.105453.2949 · 2025 · External reference
Endoplasmic reticulum stress and its role in metabolic reprogramming of cancer
10.3390/metabo15040221 · 2025 · External reference
Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8(+) T cell exhaustion
10.1016/j.immuni.2016.07.008 · 2016 · External reference
Metabolic competition in the tumor microenvironment is a driver of cancer progression
10.1016/j.cell.2015.08.016 · 2015 · External reference
Defining 'T cell exhaustion'
10.1038/s41577-019-0221-9 · 2019 · External reference
Are senescence and exhaustion intertwined or unrelated processes that compromise immunity
10.1038/nri2959 · 2011 · External reference
Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression
10.1126/sciimmunol.adn1945 · 2025 · External reference
The current state and future of T-cell exhaustion research
10.1093/oxfimm/iqad006 · 2023 · External reference
Application of ATAC-seq in tumor-specific T cell exhaustion
10.1038/s41417-022-00495-w · 2023 · External reference
Schrödinger's T cells: Molecular insights into stemness and exhaustion
10.3389/fimmu.2021.725618 · 2021 · External reference
The epigenetic landscape of T cell exhaustion
10.1126/science.aae0491 · 2016 · External reference
A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection
10.1002/eji.201344098 · 2014 · External reference
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans
10.1038/s41590-021-00979-1 · 2021 · External reference
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation
10.1038/s41590-021-00975-5 · 2021 · External reference
Faithful modeling of terminal CD8+T cell dysfunction and epigenetic stabilization in vitro
10.1172/jci.insight.191220 · 2025 · External reference
Epigenetic regulation of CD8+ T cell exhaustion: recent advances and update
10.3389/fimmu.2025.1700039 · 2025 · External reference
Schistosomiasis induces persistent DNA methylation and tuberculosis-specific immune changes
10.4049/jimmunol.1800101 · 2018 · External reference
CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element
10.1038/s41467-022-28914-4 · 2022 · External reference
T cell exhaustion.
10.1146/annurev-immunol-090222-110914 · 2024 · External reference
Biomechanics of T cell dysfunctions in chronic diseases
10.3389/fimmu.2021.600829 · 2021 · External reference
Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives
10.1002/jlb.49.1.73 · 1991 · External reference
Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani
10.1084/jem.189.4.741 · 1999 · External reference
Neutrophils, dendritic cells and Toxoplasma
10.1016/j.ijpara.2003.11.001 · 2004 · External reference
PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection
10.1093/infdis/jis304 · 2012 · External reference
Leishmania amazonensis infection induces PD-L1 expression on dendritic cells and impairs Th1 responses in vitro and in vivo
10.1038/s41598-025-21669-0 · 2025 · External reference
Characteristics of splenic PD-1+ γδT cells in Plasmodium yoelii Nigeriensis infection
10.1007/s12026-023-09441-w · 2024 · External reference
Combinatorial Tim-3 and PD-1 activity sustains antigen-specific Th1 cell numbers during blood-stage malaria
10.1111/pim.12723 · 2020 · External reference
Temporal and spatial distribution of Toxoplasma gondii differentiation into Bradyzoites and tissue cyst formation in vivo
10.1128/iai.00254-08 · 2008 · External reference
Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade
10.1073/pnas.1015298108 · 2011 · External reference
Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease
10.1038/nm1744 · 2008 · External reference
Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients
10.1093/intimm/dxh387 · 2006 · External reference
Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites
10.1038/s41577-023-00942-1 · 2024 · External reference
Th2 cell responses in immunity and inflammation following helminth infection
10.1007/978-1-4939-2911-5_4 · 2015 · External reference
A contributory role for activated hepatic stellate cells in the dynamics of Schistosoma japonicum egg-induced fibrosis
10.1016/j.ijpara.2006.04.015 · 2006 · External reference
Polyinosinic-polycytidylic acid attenuates hepatic fibrosis in C57BL/6 mice with Schistosoma japonicum infection
10.1016/j.actatropica.2011.10.008 · 2012 · External reference
Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni
10.1084/jem.173.1.159 · 1991 · External reference
Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression
10.1172/jci36534 · 2009 · External reference
Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection
10.1371/journal.ppat.1003215 · 2013 · External reference
Neuroimmune-endocrine modulation of T-cell exhaustion in central nervous system parasitic diseases: Insights from toxoplasmosis and neurocysticercosis
10.1159/000548276 · 2025 · External reference
Immunotherapeutic potential of a PD-1-blocking monoclonal antibody in experimental chronic infection caused by Leishmania mexicana through the enhancement of progenitor-like CXCR5+ and intermediate CXCR5+TIM-3+ subsets of exhausted T cells
10.3389/fimmu.2026.1827753 · 2026 · External reference
Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease
10.1371/journal.pone.0035966 · 2012 · External reference
Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells
10.1371/journal.pone.0035466 · 2012 · External reference
Increased expression of multiple co-inhibitory molecules on malaria-induced CD8+ T cells are associated with increased function instead of exhaustion
10.3389/fimmu.2022.878320 · 2022 · External reference
Author correction: Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade
10.1038/s41467-024-51832-6 · 2024 · External reference
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
10.1038/nature05115 · 2006 · External reference
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection
10.1084/jem.20132577 · 2014 · External reference
The role of TNF superfamily members in T-cell function and diseases
10.1038/nri2526 · 2009 · External reference
Mechanisms of costimulation
10.1111/j.1600-065x.2009.00784.x · 2009 · External reference
Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy
10.1172/jci13220 · 2001 · External reference
Second signals for cancer immunotherapy
10.1136/jitc-2024-010530 · 2025 · External reference
The B7:CD28 family and friends: Unraveling coinhibitory interactions
10.1016/j.immuni.2024.01.013 · 2024 · External reference
Immune tolerance regulation is critical to immune homeostasis
10.1155/jimr/5006201 · 2025 · External reference
Modulation of experimental blood stage malaria through blockade of the B7/CD28 T-cell costimulatory pathway
10.1046/j.1365-2567.1999.00718.x · 1999 · External reference
Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD44 T cell responses
10.1371/journal.ppat.1003906 · 2014 · External reference
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent
10.1126/science.aaf0683 · 2017 · External reference
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
10.1038/s41586-019-1325-x · 2019 · External reference
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
10.1016/j.immuni.2023.11.005 · 2023 · External reference
T-cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor-exhausted T cells to terminally exhausted T cells
10.1002/ctm2.70609 · 2026 · External reference
Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection
10.1016/j.celrep.2025.115861 · 2025 · External reference
The transcription factor NFAT1 participates in the induction of CD4+ T cell functional exhaustion during Plasmodium yoelii infection
10.1128/iai.00364-17 · 2017 · External reference
Redefining chronic toxoplasmosis--a T cell exhaustion perspective
10.1371/journal.ppat.1002903 · 2012 · External reference
Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis
10.1084/jem.20151995 · 2016 · External reference
Toxoplasma gondii: CD8 T cells cry for CD4 help
10.3389/fcimb.2019.00136 · 2019 · External reference
Regulatory T cells in parasite infections: Susceptibility, specificity and specialisation
10.1016/j.pt.2023.04.002 · 2023 · External reference
The development and function of regulatory T cells
10.1007/s00018-009-0026-2 · 2009 · External reference
The dynamics of Treg/Th17 and the imbalance of Treg/Th17 in Clonorchis sinensis-infected mice
10.1371/journal.pone.0143217 · 2015 · External reference
Suppressive mechanisms by Heligmosomoides polygyrus-induced Tregs in C57BL/6 mice change over time and differ to that of naïve mice
10.1002/eji.201948392 · 2020 · External reference
Regulatory T cells and parasites
10.1155/2011/520940 · 2011 · External reference
Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection
10.4049/jimmunol.1202502 · 2014 · External reference
CD4+CD25hiFOXP3+ regulatory T cells and cytokine responses in human schistosomiasis before and after treatment with praziquantel
10.1371/journal.pntd.0003995 · 2015 · External reference
CD39 expression by regulatory T cells participates in CD8+ T cell suppression during experimental Trypanosoma cruzi infection
10.1371/journal.ppat.1012191 · 2024 · External reference
Immunoendocrine dysbalance during uncontrolled T. cruzi infection is associated with the acquisition of a Th-1-like phenotype by Foxp3(+) T cells
10.1016/j.bbi.2014.11.016 · 2015 · External reference
A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria
10.2353/ajpath.2007.061033 · 2007 · External reference
CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo
10.1371/journal.ppat.1001221 · 2010 · External reference
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
10.1038/nature01152 · 2002 · External reference
Regulatory T-cell profile in early and late lesions of cutaneous leishmaniasis due to Leishmania major
2012 · External reference
Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice
10.1371/journal.ppat.1010596 · 2022 · External reference
PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection
10.1038/s41590-022-01170-w · 2022 · External reference
Take my breath away-mitochondrial dysfunction drives CD8+ T cell exhaustion
10.1038/s41435-023-00233-8 · 2024 · External reference
The TOX subfamily: All-round players in the immune system
10.1093/cei/uxac037 · 2022 · External reference
Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: Potential impact for immunotherapy
10.1007/s00432-022-04440-0 · 2023 · External reference
Hypoxia supports differentiation of terminally exhausted CD8 T cells
10.3389/fimmu.2021.660944 · 2021 · External reference
Hypoxia-driven immunosuppressive metabolites in the tumor microenvironment: New approaches for combinational immunotherapy
10.3389/fimmu.2018.01591 · 2018 · External reference
Combination immunotherapy in hepatocellular carcinoma: Synergies among immune checkpoints, TKIs, and chemotherapy
10.1186/s13045-025-01739-6 · 2025 · External reference
Dysregulation in CD39/CD73 axis may trigger the upsurge of the immune suppressive agent adenosine in OSA patients
10.1016/j.arbres.2024.02.013 · 2024 · External reference
A2A adenosine receptor gene deletion or synthetic A2A antagonist liberate tumor-reactive CD8+ T cells from tumor-induced immunosuppression
10.4049/jimmunol.1700850 · 2018 · External reference
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming
10.1038/s41467-023-42634-3 · 2023 · External reference
PD-1+ CD4 T cell immune response is mediated by HIF-1α/NFATc1 pathway after P. yoelii infection
10.3389/fimmu.2022.942862 · 2022 · External reference
HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis
10.1371/journal.ppat.1006616 · 2017 · External reference
HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis
10.1038/s41598-018-21891-z · 2018 · External reference
Virtual memory CD8+ T cells: Origin and beyond
10.1089/jir.2022.0053 · 2022 · External reference
Similar but different: Virtual memory CD8 T cells as a memory-like cell population
10.1111/imcb.12277 · 2019 · External reference
Roles of virtual memory T cells in diseases
10.4110/in.2023.23.e11 · 2023 · External reference
Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection
10.1038/s41385-018-0100-x · 2019 · External reference
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection
10.1038/s41467-018-06978-5 · 2018 · External reference
UFL1 promotes survival and function of virtual memory CD8 T cells
10.1093/jimmun/vkae042 · 2025 · External reference
IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells
10.1126/sciimmunol.adk4841 · 2025 · External reference
LCMV-mediated loss of virtual memory CD8 T cells yields a functionally enhanced T cell subset
10.1016/j.isci.2025.113893 · 2025 · External reference
Evolution of our understanding of myeloid regulatory cells: From MDSCs to Mregs
10.3389/fimmu.2014.00303 · 2014 · External reference
History of myeloid-derived suppressor cells
10.1038/nrc3581 · 2013 · External reference
A Schistosoma japonicum infection promotes the expansion of myeloid-derived suppressor cells by activating the JAK/STAT3 pathway
10.4049/jimmunol.1601860 · 2017 · External reference
Myeloid-derived suppressor cells: The expanding world of helminth modulation of the immune system
10.3389/fimmu.2022.874308 · 2022 · External reference
Modulation of CD8(+) T-cell activation events by monocytic and granulocytic myeloid-derived suppressor cells
10.1016/j.imbio.2013.07.003 · 2013 · External reference
Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer
10.18632/oncotarget.3682 · 2015 · External reference
Emerging role of MDSCs as novel biomarkers and therapeutic targets for cancer immunotherapy
10.2147/itt.s485642 · 2025 · External reference
Myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment and their targeting in cancer therapy
10.1186/s12943-024-02208-3 · 2025 · External reference
IRF4 regulates myeloid-derived suppressor cells expansion and function in Schistosoma japonicum-infected mice
10.1186/s13071-024-06543-8 · 2024 · External reference
Proliferation of MDSCs may indicate a lower CD4+ T cell immune response in schistosomiasis japonica. La prolifération des MDSC peut indiquer une réponse immunitaire des lymphocytes T CD4+ plus faible dans la schistosomiase japonica
10.1051/parasite/2024050 · 2024 · External reference
The expression of CTLA-4 in hepatic alveolar echinococcosis patients and blocking CTLA-4 to reverse T cell exhaustion in Echinococcus multilocularis-infected mice
10.3389/fimmu.2024.1358361 · 2024 · External reference
Immune exhaustion of T cells in alveolar echinococcosis patients and its reversal by blocking checkpoint receptor TIGIT in a murine model
10.1002/hep.30896 · 2020 · External reference
Role of the PD-1/PD-L1 pathway in experimental Trypanosoma cruzi infection and potential therapeutic options
10.3389/fimmu.2022.866120 · 2022 · External reference
The expression of PD-1 and its ligands increases in Leishmania infection and its blockade reduces the parasite burden
10.1016/j.cyto.2022.155839 · 2022 · External reference
Blockade of Tim-3 pathway in a mouse model of toxoplasmosis: impact on brain leukocyte infiltration, parasite burden, and neuroinflammation
10.1038/s41598-026-49283-8 · 2026 · External reference
Upregulation of LAG3 modulates the immune imbalance of CD4+ T-cell subsets and exacerbates disease progression in patients with alveolar echinococcosis and a mouse model
10.1371/journal.ppat.1011396 · 2023 · External reference
T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function in mice
10.1002/eji.202149424 · 2022 · External reference
Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses
10.3389/fimmu.2020.576743 · 2021 · External reference
PARP1-NFATc1-PD1 pathway of maturation and stability of CD8+T cells is beneficial against chronic Trypanosoma cruzi infection
10.1016/j.isci.2025.112926 · 2025 · External reference
mRNA vaccination overcomes hemozoin-mediated impairment of whole parasite vaccine efficacy for malaria
10.1101/2025.10.29.685344 · 2025 · External reference
CD8+ T-cell exhaustion phenotype in chronic hepatitis C virus infection is associated with epitope sequence variation
10.3389/fimmu.2022.832206 · 2022 · External reference
Human T-cell lymphotropic/leukemia virus type 1 (HTLV-1) Tax-specific T-cell exhaustion in HTLV-1-infected individuals
10.1111/cas.13654 · 2018 · External reference
Early effects of HTLV-1 infection on the activation, exhaustion, and differentiation of T-cells in humanized NSG mice
10.3390/cells10102514 · 2021 · External reference
Cytokine storm promoting T cell exhaustion in severe COVID-19 revealed by single cell sequencing data analysis
10.1093/pcmedi/pbac014 · 2022 · External reference
CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection
10.1128/iai.01184-15 · 2015 · External reference
Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing Malignancy
10.1371/journal.pone.0093523 · 2014 · External reference
TIM3 mediates T cell exhaustion during Mycobacterium tuberculosis infection
10.1371/journal.ppat.1005490 · 2016 · External reference
Restoration of T cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration
10.1371/journal.pone.0199497 · 2018 · External reference
Targeting the host response in sepsis: current approaches and future evidence
10.1186/s13054-023-04762-6 · 2023 · External reference
Acute viral respiratory infection rapidly induces a CD8+ T cell exhaustion-like phenotype
10.4049/jimmunol.1403004 · 2015 · External reference
Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis
10.4049/jimmunol.180.11.7506 · 2008 · External reference
Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity
10.4049/jimmunol.0803557 · 2009 · External reference
Precursors of exhausted T cells are pre-emptively formed in acute infection
10.1038/s41586-024-08451-4 · 2025 · External reference
