Research graph
References from Integrated single-cell analysis characterizes malignant epithelial programs and context-dependent immune associations of MP7/SERINC2 in colorectal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
10.3322/caac.21834 · 2024 · External reference
Comprehensive molecular characterization of human colon and rectal cancer
10.1038/nature11252 · 2012 · External reference
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
10.1016/s0140-6736(18)30789-x · 2018 · External reference
Pembrolizumab in microsatellite-instability-high advanced colorectal cancer
10.1056/nejmoa2017699 · 2020 · External reference
The consensus molecular subtypes of colorectal cancer
10.1038/nm.3967 · 2015 · External reference
Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer
10.1038/s41588-022-01100-4 · 2022 · External reference
Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer
10.1038/s41588-020-0636-z · 2020 · External reference
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer
10.15252/emmm.202114123 · 2021 · External reference
Spatially organized multicellular immune hubs in human colorectal cancer
10.1016/j.cell.2021.08.003 · 2021 · External reference
Refining colorectal cancer classification and clinical stratification through a single-cell atlas
10.1186/s13059-022-02677-z · 2022 · External reference
Single-cell chromatin accessibility analysis reveals the epigenetic basis and signature transcription factors for the molecular subtypes of colorectal cancers
10.1158/2159-8290.cd-23-1445 · 2024 · External reference
Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-seq
10.7554/elife.43803 · 2019 · External reference
SCENIC: single-cell regulatory network inference and clustering
10.1038/nmeth.4463 · 2017 · External reference
A scalable SCENIC workflow for single-cell gene regulatory network analysis
10.1038/s41596-020-0336-2 · 2020 · External reference
D-SPIN constructs regulatory network models from scRNA-seq that reveal organizing principles of perturbation response
10.1016/j.cell.2026.04.028 · 2026 · External reference
An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types
10.1007/s00109-009-0467-y · 2009 · External reference
Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study
10.1371/journal.pone.0103159 · 2014 · External reference
Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value
10.1371/journal.pmed.1001453 · 2013 · External reference
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer
10.1053/j.gastro.2009.11.005 · 2010 · External reference
Scrublet: computational identification of cell doublets in single-cell transcriptomic data
10.1016/j.cels.2018.11.005 · 2019 · External reference
Solo: doublet identification in single-cell RNA-seq via semi-supervised deep learning
10.1016/j.cels.2020.05.010 · 2020 · External reference
Deep generative modeling for single-cell transcriptomics
10.1038/s41592-018-0229-2 · 2018 · External reference
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
10.1126/science.1254257 · 2014 · External reference
scMalignantFinder distinguishes Malignant cells in single-cell and spatial transcriptomics by leveraging cancer signatures
10.1038/s42003-025-07942-y · 2025 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
The Molecular Signatures Database (MSigDB) hallmark gene set collection
10.1016/j.cels.2015.12.004 · 2015 · External reference
Improved reconstruction of single-cell developmental potential with CytoTRACE 2
10.1038/s41592-025-02857-2 · 2025 · External reference
GSVA: gene set variation analysis for microarray and RNA-seq data
10.1186/1471-2105-14-7 · 2013 · External reference
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression
10.1186/s13059-016-1070-5 · 2016 · External reference
CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models
10.1038/s41598-017-16747-x · 2017 · External reference
Regularization paths for generalized linear models via coordinate descent
10.18637/jss.v033.i01 · 2010 · External reference
Random survival forests
10.1214/08-aoas169 · 2008 · External reference
XGBoost: a scalable tree boosting system
10.1145/2939672.2939785 · 2016 · External reference
From local explanations to global understanding with explainable AI for trees
10.1038/s42256-019-0138-9 · 2020 · External reference
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
10.1186/1471-2105-9-14 · 2008 · External reference
SCANPY: large-scale single-cell gene expression data analysis
10.1186/s13059-017-1382-0 · 2018 · External reference
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
10.1007/s10238-024-01515-9 · 2025 · External reference
Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer
10.1016/j.ccell.2024.06.009 · 2024 · External reference
Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies
10.3389/fonc.2023.1193665 · 2023 · External reference
Prognostic value of microRNAs in colorectal cancer: a meta-analysis
10.2147/cmar.s157493 · 2018 · External reference
A pair-wise meta-analysis highlights circular RNAs as potential biomarkers for colorectal cancer
10.1186/s12885-019-6136-9 · 2019 · External reference
Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis
10.1074/jbc.m505712200 · 2005 · External reference
SERINC2-knockdown inhibits proliferation, migration and invasion in lung adenocarcinoma
10.3892/ol.2018.9403 · 2018 · External reference
Serinc2 drives the progression of cervical cancer through regulating Myc pathway
10.1002/cam4.70296 · 2024 · External reference
SERINC2-mediated serine metabolism promotes cervical cancer progression and drives T cell exhaustion
10.7150/ijbs.105572 · 2025 · External reference
