Research graph
References from Enrichment of the TRIM21-IgG complex in placental villi during HIV-1 infection. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
10.1002/14651858.cd003510.pub2 · 2011 · External reference
Vertical transmission of HIV-1 infection
10.1016/s0035-9203(00)90413-9 · 2000 · External reference
Increased expression on innate immune factors in placentas from HIV-infected mothers concurs with dampened systemic immune activation
10.3389/fimmu.2020.01822 · 2020 · External reference
Upregulation of innate antiviral restricting factor expression in the cord blood and decidual tissue of HIV-infected mothers
10.1371/journal.pone.0084917 · 2013 · External reference
TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
10.1002/bies.20304 · 2005 · External reference
TRIM proteins in blood cancers
10.1007/s12079-017-0423-5 · 2018 · External reference
Antiretroviral potential of human tripartite motif-5 and related proteins
10.1016/j.virol.2006.05.035 · 2006 · External reference
TRIM family proteins and their emerging roles in innate immunity
10.1038/nri2413 · 2008 · External reference
TRIM family proteins: retroviral restriction and antiviral defence
10.1038/nrmicro1248 · 2005 · External reference
Restriction of HIV-1 and other retroviruses by TRIM5
10.1038/s41579-019-0225-2 · 2019 · External reference
A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
10.7554/elife.39823 · 2018 · External reference
The interferon-stimulated gene TRIM22: A double-edged sword in HIV-1 infection
10.1016/j.cytogfr.2018.02.001 · 2018 · External reference
TRIM21-from intracellular immunity to therapy
10.3389/fimmu.2019.02049 · 2019 · External reference
Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors
10.1371/journal.pone.0011776 · 2010 · External reference
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3
10.4049/jimmunol.181.3.1780 · 2008 · External reference
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
10.1084/jem.21210oia77 · 2015 · External reference
TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity
10.15252/embr.201847528 · 2020 · External reference
CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins
10.1080/15548627.2023.2281128 · 2024 · External reference
TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin
10.1007/s00018-015-2040-x · 2016 · External reference
TRIM8/GERP RING finger protein interacts with SOCS-1
10.1074/jbc.m205900200 · 2002 · External reference
TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells
10.1126/sciadv.aax3511 · 2019 · External reference
TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination
10.1007/s10565-022-09768-4 · 2023 · External reference
HIV, placental pathology, and birth outcomes-a brief overview
10.1201/9781420039368.ch1 · 2021 · External reference
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
10.1093/nar/gkq537 · 2010 · External reference
g:Profiler-interoperable web service for functional enrichment analysis and gene identifier mapping (2023 update)
10.1093/nar/gkad347 · 2023 · External reference
TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization
10.3389/fimmu.2024.1401471 · 2024 · External reference
Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting
10.1038/s41419-021-03989-x · 2021 · External reference
Differential impact of antiretroviral therapy initiated before or during pregnancy on placenta pathology in HIV-positive women
10.1097/qad.0000000000002824 · 2021 · External reference
Placental pathology in HIV infection at term: a comparison with HIV-uninfected women
10.1111/tmi.12858 · 2017 · External reference
The emerging roles of ubiquitin-like modifications in regulating HIV replication and host defense
10.3389/fcimb.2025.1593445 · 2025 · External reference
Role of the ubiquitin proteasome system (UPS) in the HIV-1 life cycle
10.3390/ijms20122984 · 2019 · External reference
The broad-spectrum antiviral functions of IFIT and IFITM proteins
10.1038/nri3344 · 2013 · External reference
ISG15 in antiviral immunity and beyond
10.1038/s41579-018-0020-5 · 2018 · External reference
N-Myc and STAT interactor as a context-dependent switch in innate antiviral immunity
10.3389/fimmu.2026.1864248 · 2026 · External reference
HIV-related differences in placental immunology: Data from the PRACHITi cohort in Pune, India
10.1093/ofid/ofaf047 · 2025 · External reference
Maternal HIV infection and placental malaria reduce transplacental antibody transfer and tetanus antibody levels in newborns in Kenya
10.1086/519845 · 2007 · External reference
HIV-1 is associated with lower Group B Streptococcus capsular and surface-protein IgG antibody levels and reduced transplacental antibody transfer in pregnant women
10.1097/qco.0000000000000266 · 2015 · External reference
Maternally acquired immunity in newborns from women infected by the human immunodeficiency virus
10.1111/j.1651-2227.1993.tb12805.x · 1993 · External reference
Placental transfer and maternally acquired neonatal IgG immunity in human immunodeficiency virus infection
10.1093/infdis/173.5.1077 · 1996 · External reference
Fc characteristics mediate selective placental transfer of IgG in HIV-infected women
10.1016/j.cell.2019.05.046 · 2019 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events
10.4161/cc.28401 · 2014 · External reference
Quick-and-clean article figures with FigureJ
10.1111/jmi.12069 · 2013 · External reference
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
10.1002/14651858.cd003510.pub2 · ExternalCitation · doi-reference
TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
10.1002/bies.20304 · ExternalCitation · doi-reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · ExternalCitation · doi-reference
TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin
10.1007/s00018-015-2040-x · ExternalCitation · doi-reference
TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination
10.1007/s10565-022-09768-4 · ExternalCitation · doi-reference
TRIM proteins in blood cancers
10.1007/s12079-017-0423-5 · ExternalCitation · doi-reference
Fc characteristics mediate selective placental transfer of IgG in HIV-infected women
10.1016/j.cell.2019.05.046 · ExternalCitation · doi-reference
The interferon-stimulated gene TRIM22: A double-edged sword in HIV-1 infection
10.1016/j.cytogfr.2018.02.001 · ExternalCitation · doi-reference
Antiretroviral potential of human tripartite motif-5 and related proteins
10.1016/j.virol.2006.05.035 · ExternalCitation · doi-reference
Vertical transmission of HIV-1 infection
10.1016/s0035-9203(00)90413-9 · ExternalCitation · doi-reference
TRIM family proteins and their emerging roles in innate immunity
10.1038/nri2413 · ExternalCitation · doi-reference
The broad-spectrum antiviral functions of IFIT and IFITM proteins
10.1038/nri3344 · ExternalCitation · doi-reference
TRIM family proteins: retroviral restriction and antiviral defence
10.1038/nrmicro1248 · ExternalCitation · doi-reference
Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting
10.1038/s41419-021-03989-x · ExternalCitation · doi-reference
ISG15 in antiviral immunity and beyond
10.1038/s41579-018-0020-5 · ExternalCitation · doi-reference
Restriction of HIV-1 and other retroviruses by TRIM5
10.1038/s41579-019-0225-2 · ExternalCitation · doi-reference
TRIM8/GERP RING finger protein interacts with SOCS-1
10.1074/jbc.m205900200 · ExternalCitation · doi-reference
CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins
10.1080/15548627.2023.2281128 · ExternalCitation · doi-reference
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
10.1084/jem.21210oia77 · ExternalCitation · doi-reference
Maternal HIV infection and placental malaria reduce transplacental antibody transfer and tetanus antibody levels in newborns in Kenya
10.1086/519845 · ExternalCitation · doi-reference
Placental transfer and maternally acquired neonatal IgG immunity in human immunodeficiency virus infection
10.1093/infdis/173.5.1077 · ExternalCitation · doi-reference
g:Profiler-interoperable web service for functional enrichment analysis and gene identifier mapping (2023 update)
10.1093/nar/gkad347 · ExternalCitation · doi-reference
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
10.1093/nar/gkq537 · ExternalCitation · doi-reference
HIV-related differences in placental immunology: Data from the PRACHITi cohort in Pune, India
10.1093/ofid/ofaf047 · ExternalCitation · doi-reference
Differential impact of antiretroviral therapy initiated before or during pregnancy on placenta pathology in HIV-positive women
10.1097/qad.0000000000002824 · ExternalCitation · doi-reference
HIV-1 is associated with lower Group B Streptococcus capsular and surface-protein IgG antibody levels and reduced transplacental antibody transfer in pregnant women
10.1097/qco.0000000000000266 · ExternalCitation · doi-reference
Maternally acquired immunity in newborns from women infected by the human immunodeficiency virus
10.1111/j.1651-2227.1993.tb12805.x · ExternalCitation · doi-reference
Quick-and-clean article figures with FigureJ
10.1111/jmi.12069 · ExternalCitation · doi-reference
Placental pathology in HIV infection at term: a comparison with HIV-uninfected women
10.1111/tmi.12858 · ExternalCitation · doi-reference
TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells
10.1126/sciadv.aax3511 · ExternalCitation · doi-reference
HIV, placental pathology, and birth outcomes-a brief overview
10.1201/9781420039368.ch1 · ExternalCitation · doi-reference
Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors
10.1371/journal.pone.0011776 · ExternalCitation · doi-reference
Upregulation of innate antiviral restricting factor expression in the cord blood and decidual tissue of HIV-infected mothers
10.1371/journal.pone.0084917 · ExternalCitation · doi-reference
TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity
10.15252/embr.201847528 · ExternalCitation · doi-reference
The emerging roles of ubiquitin-like modifications in regulating HIV replication and host defense
10.3389/fcimb.2025.1593445 · ExternalCitation · doi-reference
TRIM21-from intracellular immunity to therapy
10.3389/fimmu.2019.02049 · ExternalCitation · doi-reference
Increased expression on innate immune factors in placentas from HIV-infected mothers concurs with dampened systemic immune activation
10.3389/fimmu.2020.01822 · ExternalCitation · doi-reference
TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization
10.3389/fimmu.2024.1401471 · ExternalCitation · doi-reference
N-Myc and STAT interactor as a context-dependent switch in innate antiviral immunity
10.3389/fimmu.2026.1864248 · ExternalCitation · doi-reference
Role of the ubiquitin proteasome system (UPS) in the HIV-1 life cycle
10.3390/ijms20122984 · ExternalCitation · doi-reference
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3
10.4049/jimmunol.181.3.1780 · ExternalCitation · doi-reference
Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events
10.4161/cc.28401 · ExternalCitation · doi-reference
A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
10.7554/elife.39823 · ExternalCitation · doi-reference
