Research graph
References from Exogenous IFN-α delivered as an intranasal adjunct to systemic vaccination directs vaccine-specific T-cell responses to the upper respiratory tract. Local targets link to admitted publications; unresolved targets remain external evidence.
Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children
10.1038/s41587-021-01037-9 · 2022 · External reference
Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers
10.1016/j.xcrm.2021.100421 · 2021 · External reference
Mucosal correlates of protection after influenza viral challenge of vaccinated and unvaccinated healthy volunteers
10.1128/mbio.02372-23 · 2024 · External reference
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination
10.1016/j.ebiom.2022.104402 · 2023 · External reference
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
10.1038/s41586-020-2608-y · 2020 · External reference
Respiratory mucosal immunity against SARS-CoV-2 following mRNA vaccination
10.1126/sciimmunol.add4853 · 2022 · External reference
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity
10.1084/jem.20220780 · 2022 · External reference
Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines
10.1016/j.molmed.2023.01.003 · 2023 · External reference
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses
10.1126/science.abo2523 · 2022 · External reference
A "prime-pull" vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in mice
10.1371/journal.pone.0080559 · 2013 · External reference
Successful application of prime and pull strategy for a therapeutic HSV vaccine
10.1038/s41541-019-0129-1 · 2019 · External reference
Resident memory CD8(+) T cells in the upper respiratory tract prevent pulmonary influenza virus infection
10.1126/sciimmunol.aam6970 · 2017 · External reference
Generation of B-cell-based cellular vaccine for cancer in murine models
10.1016/j.xpro.2023.102219 · 2023 · External reference
Type I IFNs enhance the terminal differentiation of dendritic cells
10.4049/jimmunol.161.4.1947 · 1998 · External reference
Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics
10.1084/jem.20210583 · 2021 · External reference
Advances in anti-viral immune defence: revealing the importance of the IFN JAK/STAT pathway
10.1007/s00018-017-2520-2 · 2017 · External reference
Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors
10.1038/s41385-018-0097-1 · 2019 · External reference
Mechanisms of transendothelial migration of leukocytes
10.1161/circresaha.109.200717 · 2009 · External reference
CXCR3 ligands: redundant, collaborative and antagonistic functions
10.1038/icb.2010.158 · 2011 · External reference
Type I interferons produced by dendritic cells promote their phenotypic and functional activation
10.1182/blood.v99.9.3263 · 2002 · External reference
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells
10.1084/jem.20102545 · 2011 · External reference
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin
10.1038/ni.2744 · 2013 · External reference
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
10.1038/35005534 · 1999 · External reference
Inflammation induces dermal Vγ4+ γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17-driven responses
10.1073/pnas.1508990112 · 2015 · External reference
IL-17-producing γδ T cells switch migratory patterns between resting and activated states
10.1038/ncomms15632 · 2017 · External reference
Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells
10.1038/ni.2745 · 2013 · External reference
Intramuscular vaccination targeting mucosal tumor draining lymph node enhances integrins-mediated CD8+ T cell infiltration to control mucosal tumor growth
10.1080/2162402x.2018.1463946 · 2018 · External reference
Intramuscular inoculation of mice with the live-attenuated recombinant rabies virus TriGAS results in a transient infection of the draining lymph nodes and a robust, long-lasting protective immune response against rabies
10.1128/jvi.02589-12 · 2013 · External reference
Near-infrared fluorescence imaging directly visualizes lymphatic drainage pathways and connections between superficial and deep lymphatic systems in the mouse hindlimb
10.1038/s41598-018-25383-y · 2018 · External reference
Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells
10.4049/jimmunol.178.3.1512 · 2007 · External reference
Specialized immune responses in the peritoneal cavity and omentum
10.1002/jlb.5mir0720-271rr · 2021 · External reference
Peritoneal Administration of a Subunit Vaccine Encapsulated in a Nanodelivery System Not Only Augments Systemic Responses against SARS-CoV-2 but Also Stimulates Responses in the Respiratory Tract
10.3390/v13112202 · 2021 · External reference
Unresolved reference
External reference
Imperfect vaccination can enhance the transmission of highly virulent pathogens
10.1371/journal.pbio.1002198 · 2015 · External reference
Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains
10.1038/s41598-021-95025-3 · 2021 · External reference
Specialized immune responses in the peritoneal cavity and omentum
10.1002/jlb.5mir0720-271rr · ExternalCitation · doi-reference
Advances in anti-viral immune defence: revealing the importance of the IFN JAK/STAT pathway
10.1007/s00018-017-2520-2 · ExternalCitation · doi-reference
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination
10.1016/j.ebiom.2022.104402 · ExternalCitation · doi-reference
Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines
10.1016/j.molmed.2023.01.003 · ExternalCitation · doi-reference
Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers
10.1016/j.xcrm.2021.100421 · ExternalCitation · doi-reference
Generation of B-cell-based cellular vaccine for cancer in murine models
10.1016/j.xpro.2023.102219 · ExternalCitation · doi-reference
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
10.1038/35005534 · ExternalCitation · doi-reference
CXCR3 ligands: redundant, collaborative and antagonistic functions
10.1038/icb.2010.158 · ExternalCitation · doi-reference
IL-17-producing γδ T cells switch migratory patterns between resting and activated states
10.1038/ncomms15632 · ExternalCitation · doi-reference
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin
10.1038/ni.2744 · ExternalCitation · doi-reference
Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells
10.1038/ni.2745 · ExternalCitation · doi-reference
Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors
10.1038/s41385-018-0097-1 · ExternalCitation · doi-reference
Successful application of prime and pull strategy for a therapeutic HSV vaccine
10.1038/s41541-019-0129-1 · ExternalCitation · doi-reference
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
10.1038/s41586-020-2608-y · ExternalCitation · doi-reference
Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children
10.1038/s41587-021-01037-9 · ExternalCitation · doi-reference
Near-infrared fluorescence imaging directly visualizes lymphatic drainage pathways and connections between superficial and deep lymphatic systems in the mouse hindlimb
10.1038/s41598-018-25383-y · ExternalCitation · doi-reference
Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains
10.1038/s41598-021-95025-3 · ExternalCitation · doi-reference
Inflammation induces dermal Vγ4+ γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17-driven responses
10.1073/pnas.1508990112 · ExternalCitation · doi-reference
Intramuscular vaccination targeting mucosal tumor draining lymph node enhances integrins-mediated CD8+ T cell infiltration to control mucosal tumor growth
10.1080/2162402x.2018.1463946 · ExternalCitation · doi-reference
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells
10.1084/jem.20102545 · ExternalCitation · doi-reference
Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics
10.1084/jem.20210583 · ExternalCitation · doi-reference
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity
10.1084/jem.20220780 · ExternalCitation · doi-reference
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses
10.1126/science.abo2523 · ExternalCitation · doi-reference
Resident memory CD8(+) T cells in the upper respiratory tract prevent pulmonary influenza virus infection
10.1126/sciimmunol.aam6970 · ExternalCitation · doi-reference
Respiratory mucosal immunity against SARS-CoV-2 following mRNA vaccination
10.1126/sciimmunol.add4853 · ExternalCitation · doi-reference
Intramuscular inoculation of mice with the live-attenuated recombinant rabies virus TriGAS results in a transient infection of the draining lymph nodes and a robust, long-lasting protective immune response against rabies
10.1128/jvi.02589-12 · ExternalCitation · doi-reference
Mucosal correlates of protection after influenza viral challenge of vaccinated and unvaccinated healthy volunteers
10.1128/mbio.02372-23 · ExternalCitation · doi-reference
Mechanisms of transendothelial migration of leukocytes
10.1161/circresaha.109.200717 · ExternalCitation · doi-reference
Type I interferons produced by dendritic cells promote their phenotypic and functional activation
10.1182/blood.v99.9.3263 · ExternalCitation · doi-reference
Imperfect vaccination can enhance the transmission of highly virulent pathogens
10.1371/journal.pbio.1002198 · ExternalCitation · doi-reference
A "prime-pull" vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in mice
10.1371/journal.pone.0080559 · ExternalCitation · doi-reference
Peritoneal Administration of a Subunit Vaccine Encapsulated in a Nanodelivery System Not Only Augments Systemic Responses against SARS-CoV-2 but Also Stimulates Responses in the Respiratory Tract
10.3390/v13112202 · ExternalCitation · doi-reference
Type I IFNs enhance the terminal differentiation of dendritic cells
10.4049/jimmunol.161.4.1947 · ExternalCitation · doi-reference
Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells
10.4049/jimmunol.178.3.1512 · ExternalCitation · doi-reference